EP1129008A2 - Spitzengestaltung und direktzugriffsmatrix für mikro-flüssigkeitstransfer - Google Patents
Spitzengestaltung und direktzugriffsmatrix für mikro-flüssigkeitstransferInfo
- Publication number
- EP1129008A2 EP1129008A2 EP99932267A EP99932267A EP1129008A2 EP 1129008 A2 EP1129008 A2 EP 1129008A2 EP 99932267 A EP99932267 A EP 99932267A EP 99932267 A EP99932267 A EP 99932267A EP 1129008 A2 EP1129008 A2 EP 1129008A2
- Authority
- EP
- European Patent Office
- Prior art keywords
- fluid
- tip
- tips
- transfer
- contact
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N35/1011—Control of the position or alignment of the transfer device
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0241—Drop counters; Drop formers
- B01L3/0262—Drop counters; Drop formers using touch-off at substrate or container
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0241—Drop counters; Drop formers
- B01L3/0268—Drop counters; Drop formers using pulse dispensing or spraying, eg. inkjet type, piezo actuated ejection of droplets from capillaries
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1081—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane
- G01N35/109—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane with two horizontal degrees of freedom
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00306—Reactor vessels in a multiple arrangement
- B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
- B01J2219/00315—Microtiter plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00306—Reactor vessels in a multiple arrangement
- B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
- B01J2219/00315—Microtiter plates
- B01J2219/00317—Microwell devices, i.e. having large numbers of wells
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00364—Pipettes
- B01J2219/00367—Pipettes capillary
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00364—Pipettes
- B01J2219/00367—Pipettes capillary
- B01J2219/00369—Pipettes capillary in multiple or parallel arrangements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00378—Piezo-electric or ink jet dispensers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00527—Sheets
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00608—DNA chips
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/0061—The surface being organic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00612—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports the surface being inorganic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00614—Delimitation of the attachment areas
- B01J2219/00621—Delimitation of the attachment areas by physical means, e.g. trenches, raised areas
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00722—Nucleotides
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00178—Special arrangements of analysers
- G01N2035/00237—Handling microquantities of analyte, e.g. microvalves, capillary networks
Applications Claiming Priority (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9192898P | 1998-07-07 | 1998-07-07 | |
US91928P | 1998-07-07 | ||
US10671998P | 1998-11-02 | 1998-11-02 | |
US106719P | 1998-11-02 | ||
US11306298P | 1998-12-21 | 1998-12-21 | |
US113062P | 1998-12-21 | ||
US13846499P | 1999-06-10 | 1999-06-10 | |
US138464P | 1999-06-10 | ||
US13902499P | 1999-06-14 | 1999-06-14 | |
US139024P | 1999-06-14 | ||
PCT/US1999/015214 WO2000001798A2 (en) | 1998-07-07 | 1999-07-07 | Tip design and random access array for microfluidic transfer |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1129008A2 true EP1129008A2 (de) | 2001-09-05 |
EP1129008A4 EP1129008A4 (de) | 2001-12-05 |
Family
ID=27536617
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP99932267A Withdrawn EP1129008A4 (de) | 1998-07-07 | 1999-07-07 | Spitzengestaltung und direktzugriffsmatrix für mikro-flüssigkeitstransfer |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1129008A4 (de) |
CN (1) | CN1315913A (de) |
AU (1) | AU4861099A (de) |
WO (1) | WO2000001798A2 (de) |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2000157272A (ja) * | 1998-12-01 | 2000-06-13 | Hitachi Software Eng Co Ltd | バイオチップ及びその製造方法 |
NZ513390A (en) | 1999-03-19 | 2003-01-31 | Genencor Int | Multi-through hole testing plate for high throughput screening |
US6589791B1 (en) | 1999-05-20 | 2003-07-08 | Cartesian Technologies, Inc. | State-variable control system |
GB9916406D0 (en) * | 1999-07-13 | 1999-09-15 | Biorobotics Ltd | Liquid transfer pin |
DE19946525A1 (de) * | 1999-09-28 | 2001-05-03 | Fraunhofer Ges Forschung | Vorrichtung zur Aufnahme und Abgabe kleinster Flüssigkeitsmengen |
US20020151040A1 (en) | 2000-02-18 | 2002-10-17 | Matthew O' Keefe | Apparatus and methods for parallel processing of microvolume liquid reactions |
JP2004502923A (ja) * | 2000-02-22 | 2004-01-29 | ジェノスペクトラ,インコーポレイティド | マイクロアレイの製造方法と製造装置 |
JP2003529056A (ja) * | 2000-02-22 | 2003-09-30 | ジェノスペクトラ,インコーポレイティド | マイクロアレイ作製技術及び装置 |
US6447723B1 (en) | 2000-03-13 | 2002-09-10 | Packard Instrument Company, Inc. | Microarray spotting instruments incorporating sensors and methods of using sensors for improving performance of microarray spotting instruments |
US6878554B1 (en) * | 2000-03-20 | 2005-04-12 | Perkinelmer Las, Inc. | Method and apparatus for automatic pin detection in microarray spotting instruments |
US6756232B1 (en) * | 2000-03-20 | 2004-06-29 | Perkinelmer Las, Inc. | Method and apparatus for producing compact microarrays |
DE10017105A1 (de) * | 2000-04-06 | 2001-10-11 | Basf Ag | Verfahren und Vorrichtung zur Herstellung von Biopolymer-Feldern |
US6943035B1 (en) * | 2000-05-19 | 2005-09-13 | Genetix Limited | Liquid dispensing apparatus and method |
US7521245B1 (en) | 2000-06-05 | 2009-04-21 | Perkinelmer Las, Inc. | Method for washing and drying pins in microarray spotting instruments |
JP2004513376A (ja) * | 2000-11-17 | 2004-04-30 | テカン・トレーディング・アクチェンゲゼルシャフト | 液体サンプルを分配または吸引/分配するための装置およびシステム |
US6613284B2 (en) * | 2001-02-01 | 2003-09-02 | V&P Scientific, Inc. | Microarrayer |
DE60229173D1 (de) * | 2001-02-06 | 2008-11-13 | Parallel Synthesis Technologie | Durch mikrofabrikation hergestellte betupfungsvorrichtung zur herstellung von mikromatrizen |
CH694754A5 (de) * | 2001-03-15 | 2005-07-15 | Tecan Trading Ag | Pipettenspitze. |
CN1385518A (zh) * | 2001-04-23 | 2002-12-18 | 株式会社百尼尔 | 生物学试料的微细排列用点样装置及该装置中使用的点样针 |
US6558907B2 (en) | 2001-05-16 | 2003-05-06 | Corning Incorporated | Methods and compositions for arraying nucleic acids onto a solid support |
US6752182B2 (en) * | 2001-06-28 | 2004-06-22 | Genetix Limited | Microarraying apparatus, pin head therefor and spotting method |
JP2003043041A (ja) * | 2001-08-01 | 2003-02-13 | Canon Inc | 液体吐出装置及び試料担体の製造装置 |
EP1453600A1 (de) * | 2001-08-10 | 2004-09-08 | Oxford Genome Sciences (UK) Limited | Flüssigkeitszuführungsvorrichtung und verfahren |
EP1658894A1 (de) | 2002-02-22 | 2006-05-24 | Biodot, Inc. | Vorrichtung zur kontaktlosen Tröpfchenabgabe unterhalb einer fluidischen Oberfläche |
WO2003076076A2 (de) * | 2002-03-11 | 2003-09-18 | Axaron Bioscience Ag | Aufbringen eines stoffs auf ein substrat |
JP2003329680A (ja) * | 2002-05-10 | 2003-11-19 | Hitachi Software Eng Co Ltd | スポットピン、スポッティング装置及び生体分子スポット方法 |
US8277753B2 (en) * | 2002-08-23 | 2012-10-02 | Life Technologies Corporation | Microfluidic transfer pin |
DE10255595A1 (de) | 2002-11-26 | 2004-06-03 | Cybio Ag | Mehrkanaldosiervorrichtung mit automatischer Kalibrierung |
WO2004074818A2 (en) | 2002-12-20 | 2004-09-02 | Biotrove, Inc. | Assay apparatus and method using microfluidic arrays |
WO2004067700A2 (en) * | 2003-01-31 | 2004-08-12 | Apogent Robotics Limited | Liquid transfer system |
DE10316580A1 (de) * | 2003-04-10 | 2004-11-04 | Infineon Technologies Ag | Vorrichtung zum beschädigungsfreien Aufbringen von Bio-Molekülen in Lösung auf empfindlichen Substraten |
US7488604B2 (en) * | 2003-07-11 | 2009-02-10 | Genomic Solutions Inc. | Apparatus and methods for liquid sample handling based on capillary action |
CA2559171A1 (en) | 2004-03-12 | 2005-09-29 | Biotrove, Inc. | Nanoliter array loading |
CA2564876C (en) | 2004-04-30 | 2013-04-16 | Bioforce Nanosciences, Inc. | Method and apparatus for depositing material onto a surface |
US7759062B2 (en) | 2006-06-09 | 2010-07-20 | Third Wave Technologies, Inc. | T-structure invasive cleavage assays, consistent nucleic acid dispensing, and low level target nucleic acid detection |
EP2541257A3 (de) | 2006-09-22 | 2013-01-16 | CLONDIAG GmbH | Ausgabevorrichtung für, und Verfahren zur Ausgabe einer Substanz auf ein Substrat |
US10753927B2 (en) | 2006-09-22 | 2020-08-25 | ALERE TECHNOLOGIES GmbH | Methods for detecting an analyte |
JP5632316B2 (ja) * | 2011-03-18 | 2014-11-26 | 株式会社日立ハイテクノロジーズ | 質量分析装置及びそれに用いられるイオン源 |
CN104759373B (zh) * | 2012-04-25 | 2017-08-01 | 艾博生物医药(杭州)有限公司 | 一种液体分配设备 |
CN103657548A (zh) * | 2012-08-31 | 2014-03-26 | 艾博生物医药(杭州)有限公司 | 一种自动添加液体试剂的方法及设备 |
CN106687221B (zh) * | 2014-07-25 | 2020-07-03 | 拜奥多特公司 | 具有纵向换能器和可置换毛细管的压电分配器 |
EP3197604A1 (de) * | 2014-09-23 | 2017-08-02 | Gencell Biosystems Limited | Druckbasierte ausgabe |
DE102016211496A1 (de) * | 2016-06-27 | 2017-12-28 | Robert Bosch Gmbh | Dispensnadel und System mit solch einer Dispensnadel |
EP3502650B1 (de) * | 2017-12-22 | 2023-07-19 | Universiteit Maastricht | Verfahren von und vorrichtung zum aufbringen von flüssigkeit auf einem substrat |
CN111989390A (zh) * | 2018-04-16 | 2020-11-24 | 南京金斯瑞生物科技有限公司 | 用于从样品提取生物分子的系统及相关方法 |
EP3599021B1 (de) * | 2018-07-23 | 2021-04-21 | Scienion AG | Vorrichtung und verfahren zum isolieren von einzelnen partikeln aus einer partikelsuspension |
US20210311081A1 (en) * | 2018-11-02 | 2021-10-07 | Hewlett-Packard Development Company, L.P. | Randomized dispensing order |
CN113382876B (zh) * | 2019-02-01 | 2023-04-07 | 艾斯提匹勒股份公司 | 流体打印设备 |
WO2020157548A1 (en) * | 2019-02-01 | 2020-08-06 | Xtpl S.A. | Method of printing fluid |
US20220305494A1 (en) * | 2019-08-30 | 2022-09-29 | Beijing Dawei Biotech Ltd. | Sample adding needle for preparing microdroplets and microdroplet preparation method |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR52270E (fr) * | 1942-06-04 | 1943-12-01 | Perfectionnements aux compte-gouttes, flacons, collyres, pipettes, etc. | |
WO1987007377A1 (en) * | 1986-05-20 | 1987-12-03 | Boots-Celltech Diagnostics Limited | Fluid dispensing apparatus |
GB2310006A (en) * | 1995-12-01 | 1997-08-13 | Genetix Ltd | Pneumatic actuator |
WO1997046319A1 (en) * | 1996-06-05 | 1997-12-11 | Molecular Dynamics, Inc. | High-speed liquid deposition device for biological molecule array formation |
US5741554A (en) * | 1996-07-26 | 1998-04-21 | Bio Dot, Inc. | Method of dispensing a liquid reagent |
US5743960A (en) * | 1996-07-26 | 1998-04-28 | Bio-Dot, Inc. | Precision metered solenoid valve dispenser |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3164304A (en) * | 1961-05-08 | 1965-01-05 | Standard Thomson Corp | Liquid dispensing apparatus for small quantities |
AU585033B2 (en) * | 1986-07-04 | 1989-06-08 | Tosoh Corporation | Quantitative dispenser for a liquid |
US5807522A (en) * | 1994-06-17 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for fabricating microarrays of biological samples |
-
1999
- 1999-07-07 CN CN 99810378 patent/CN1315913A/zh active Pending
- 1999-07-07 EP EP99932267A patent/EP1129008A4/de not_active Withdrawn
- 1999-07-07 WO PCT/US1999/015214 patent/WO2000001798A2/en not_active Application Discontinuation
- 1999-07-07 AU AU48610/99A patent/AU4861099A/en not_active Abandoned
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Title |
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See also references of WO0001798A2 * |
Also Published As
Publication number | Publication date |
---|---|
CN1315913A (zh) | 2001-10-03 |
WO2000001798A3 (en) | 2000-02-17 |
EP1129008A4 (de) | 2001-12-05 |
WO2000001798A2 (en) | 2000-01-13 |
AU4861099A (en) | 2000-01-24 |
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