EP1073450A4 - Proteine de surface pneumococcique c(pspc), regions epitopes et selection de souches d'une telle proteine, et utilisations correspondantes - Google Patents

Proteine de surface pneumococcique c(pspc), regions epitopes et selection de souches d'une telle proteine, et utilisations correspondantes

Info

Publication number
EP1073450A4
EP1073450A4 EP99919991A EP99919991A EP1073450A4 EP 1073450 A4 EP1073450 A4 EP 1073450A4 EP 99919991 A EP99919991 A EP 99919991A EP 99919991 A EP99919991 A EP 99919991A EP 1073450 A4 EP1073450 A4 EP 1073450A4
Authority
EP
European Patent Office
Prior art keywords
pspc
surface protein
uses therefor
pneumococcal surface
strain selection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99919991A
Other languages
German (de)
English (en)
Other versions
EP1073450A1 (fr
Inventor
David E Briles
Susan K Hollingshead
Alexis Brooks-Walter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UAB Research Foundation
Original Assignee
UAB Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UAB Research Foundation filed Critical UAB Research Foundation
Publication of EP1073450A1 publication Critical patent/EP1073450A1/fr
Publication of EP1073450A4 publication Critical patent/EP1073450A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP99919991A 1998-04-23 1999-04-23 Proteine de surface pneumococcique c(pspc), regions epitopes et selection de souches d'une telle proteine, et utilisations correspondantes Withdrawn EP1073450A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8272898P 1998-04-23 1998-04-23
US82728P 1998-04-23
PCT/US1999/008895 WO1999053940A1 (fr) 1998-04-23 1999-04-23 Proteine de surface pneumococcique c(pspc), regions epitopes et selection de souches d'une telle proteine, et utilisations correspondantes

Publications (2)

Publication Number Publication Date
EP1073450A1 EP1073450A1 (fr) 2001-02-07
EP1073450A4 true EP1073450A4 (fr) 2003-04-23

Family

ID=22173049

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99919991A Withdrawn EP1073450A4 (fr) 1998-04-23 1999-04-23 Proteine de surface pneumococcique c(pspc), regions epitopes et selection de souches d'une telle proteine, et utilisations correspondantes

Country Status (5)

Country Link
EP (1) EP1073450A4 (fr)
JP (1) JP2002516251A (fr)
AU (1) AU770378B2 (fr)
CA (1) CA2328399A1 (fr)
WO (1) WO1999053940A1 (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7078042B2 (en) * 1995-09-15 2006-07-18 Uab Research Foundation Pneumococcal surface protein C (PspC), epitopic regions and strain selection thereof, and uses therefor
HU229664B1 (en) * 1998-12-23 2014-04-28 Id Biomedical Corp Quebec Streptococcus antigens
BR0011478A (pt) * 1999-06-10 2002-03-19 Uab Research Foundation Composição de combinação imunológica, métodos de induzir uma resposta imunológica em um animal, e de imunizar um hospedeiro contra infecção pneumocócica, e, composição imunogênica para administração intranasal
GB0022742D0 (en) 2000-09-15 2000-11-01 Smithkline Beecham Biolog Vaccine
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
GB0607088D0 (en) 2006-04-07 2006-05-17 Glaxosmithkline Biolog Sa Vaccine
EP3020411A1 (fr) 2005-12-22 2016-05-18 GlaxoSmithKline Biologicals s.a. Vaccin
UA92782C2 (ru) 2006-01-17 2010-12-10 Арне Форсгрен Новый поверхностный белок haemophilus influenzae (белок е; ре)
PT2167121E (pt) 2007-06-26 2015-12-02 Glaxosmithkline Biolog Sa Vacina compreendendo conjugados de polissacáridos capsulares de streptococcus pneumoniae
GB0714963D0 (en) 2007-08-01 2007-09-12 Novartis Ag Compositions comprising antigens
US8466167B2 (en) 2008-03-03 2013-06-18 Irm Llc Compounds and compositions as TLR activity modulators
PT2271360E (pt) 2008-04-16 2015-12-07 Glaxosmithkline Biolog Sa Vacina
EP2411045A1 (fr) 2009-03-24 2012-02-01 Novartis AG Combinaisons de protéine liant le facteur h de méningocoque et de conjugués de saccharide de pneumocoque
CA2765112A1 (fr) 2009-06-10 2010-12-16 Novartis Ag Vaccins contenant de la benzonaphtyridine
JO3257B1 (ar) 2009-09-02 2018-09-16 Novartis Ag مركبات وتركيبات كمعدلات لفاعلية tlr
CA2772916C (fr) 2009-09-02 2019-01-15 Novartis Ag Compositions immunogenes comprenant des modulateurs de l'activite tlr
CN102695523A (zh) 2009-09-10 2012-09-26 诺华有限公司 针对呼吸道疾病的组合疫苗
WO2011057148A1 (fr) 2009-11-05 2011-05-12 Irm Llc Composés et compositions permettant de moduler l'activité des tlr-7
CN102762206A (zh) 2009-12-15 2012-10-31 诺华有限公司 免疫增强化合物的均匀悬液及其用途
GB201003924D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Immunogenic composition
CN102905703B (zh) 2010-03-23 2016-09-28 诺华股份有限公司 作为tlr2激动剂用于治疗感染、炎症、呼吸疾病等的化合物(基于半胱氨酸的脂肽)和组合物
WO2012072769A1 (fr) 2010-12-01 2012-06-07 Novartis Ag Epitopes rrgb de pneumocoque et combinaisons de variantes
SG194733A1 (en) 2011-05-17 2013-12-30 Glaxosmithkline Biolog Sa Vaccine against streptococcus pneumoniae
JP2015510872A (ja) 2012-03-07 2015-04-13 ノバルティス アーゲー Ｓｔｒｅｐｔｏｃｏｃｃｕｓｐｎｅｕｍｏｎｉａｅ抗原の増強された製剤
US9827190B2 (en) 2013-02-01 2017-11-28 Glaxosmithkline Biologicals Sa Intradermal delivery of immunological compositions comprising toll-like receptor 7 agonists
GB201318170D0 (en) * 2013-10-14 2013-11-27 Univ Edinburgh Proteins with Diagnostic and Therapeutic Uses
GB201518684D0 (en) 2015-10-21 2015-12-02 Glaxosmithkline Biolog Sa Vaccine
BR112020016314A2 (pt) 2018-02-12 2020-12-15 Inimmune Corporation Compostos ou um sais farmaceuticamente aceitáveis, composição farmacêutica, kit, e, métodos para elicitar, intensificar ou modificar uma resposta imunológica, para tratar, prevenir ou reduzir a suscetibilidade a câncer, para tratar, prevenir ou reduzir a suscetibilidade a uma doença infecciosa, para tratar, prevenir ou reduzir a suscetibilidade a uma alergia, para tratar, prevenir ou reduzir a suscetibilidade a uma afecção autoimune, para tratar, prevenir ou reduzir a suscetibilidade em um sujeito à infecção bacteriana, viral, priônica, autoimunidade, câncer ou alergia, para tratar, prevenir ou reduzir a suscetibilidade à autoimunidade, alergia, reperfusão de isquemia ou sepse, para tratar, prevenir ou reduzir a gravidade de ataques epiléticos e para tratar, prevenir ou reduzir a suscetibilidade a doenças oculares como degeneração macular, hipertensão ocular e infecção ocular
WO2022096596A1 (fr) 2020-11-04 2022-05-12 Eligo Bioscience Phages recombinants de cutibacterium acnes, leur procédé de production et leurs utilisations

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0622081A2 (fr) * 1993-04-20 1994-11-02 The Uab Research Foundation Sites épitopiques de la protéine A de surface de pneumocoque
WO1997009994A1 (fr) * 1995-09-15 1997-03-20 Uab Research Foundation Genes pneumococciques, parties de ces genes, leurs produits d'expression, et utilisations de ces genes, parties et produits

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5476929A (en) * 1991-02-15 1995-12-19 Uab Research Foundation Structural gene of pneumococcal protein

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0622081A2 (fr) * 1993-04-20 1994-11-02 The Uab Research Foundation Sites épitopiques de la protéine A de surface de pneumocoque
WO1997009994A1 (fr) * 1995-09-15 1997-03-20 Uab Research Foundation Genes pneumococciques, parties de ces genes, leurs produits d'expression, et utilisations de ces genes, parties et produits

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ALEXIS BROOKS-WALTER ET AL: "The pspC gene of Streptococcus pneumonia encodes a polymorphic protein, PspC, which elicits cross-reactive antibodies to PspA and provides immunity to pneumococcal bacteremia", INFECTION AND IMMUNITY, AMERICAN SOCIETY FOR MICROBIOLOGY. WASHINGTON, US, vol. 67, no. 12, December 1999 (1999-12-01), pages 6533 - 6542, XP002190970, ISSN: 0019-9567 *
See also references of WO9953940A1 *

Also Published As

Publication number Publication date
AU770378B2 (en) 2004-02-19
JP2002516251A (ja) 2002-06-04
CA2328399A1 (fr) 1999-10-28
AU3758499A (en) 1999-11-08
EP1073450A1 (fr) 2001-02-07
WO1999053940A1 (fr) 1999-10-28

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