EP0999432B1 - Procédé d' opération d' un système de dosage électronique et système de dosage pour la mise en oeuvre du procédé - Google Patents

Procédé d' opération d' un système de dosage électronique et système de dosage pour la mise en oeuvre du procédé Download PDF

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Publication number
EP0999432B1
EP0999432B1 EP99120656A EP99120656A EP0999432B1 EP 0999432 B1 EP0999432 B1 EP 0999432B1 EP 99120656 A EP99120656 A EP 99120656A EP 99120656 A EP99120656 A EP 99120656A EP 0999432 B1 EP0999432 B1 EP 0999432B1
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Prior art keywords
data
proportioning
charging
electronic control
interfaces
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German (de)
English (en)
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EP0999432A2 (fr
EP0999432A3 (fr
EP0999432B2 (fr
Inventor
Dirk Jansen
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Eppendorf SE
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Eppendorf SE
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/0227—Details of motor drive means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/02—Identification, exchange or storage of information
    • B01L2300/025—Displaying results or values with integrated means
    • B01L2300/027—Digital display, e.g. LCD, LED

Definitions

  • the invention relates to a method for operating an electronic Dosing system with an electronic manual dosing device and to a dosing system for carrying out the method.
  • Electronic dosing devices are dosed in laboratories used by liquids. They are in different versions known. After the air cushion principle working metering devices have an integrated piston-cylinder unit, by means of which an air column can be displaced is to suck sample liquid into a dosing tip and off to launch this. In this case, the piston-cylinder unit does not come in Contact with the liquid. Only the dosing tip, which is usually off Plastic is contaminated and can be replaced after use become.
  • Pistonless dosing devices can be a dosing tip with a balloon-like Have end portion, for sucking liquid expanded and compressed for ejection.
  • Such metering tips are also been designed as a replacement part.
  • Microdosing devices may be a micromembrane pump and / or have a free jet dispenser, wherein at least one of these components microsystem technology, especially in silicon, glass, Plastic injection molding and / or plastic embossing technology.
  • the dosage will achieved by deformation of a wall of a chamber containing liquid is filled.
  • the electrical drive for deforming the wall may be piezoelectric, thermoelectric, electromagnetic, electrostatic, electromechanical, magneto-restrictive etc.
  • Air cushion, direct displacement, pistonless and microdosing devices may have a fixed or a variable metering volume. A change in the dosing volume is achieved by adjusting the displacement reaches the displacement device, d. H. of the displacement path the piston or the degree of deformation of the balloon-like end portion or the chamber wall.
  • Dispensers are dosing devices that absorb a volume of fluid can deliver repetitive in small subsets.
  • All dosing devices can be designed as handsets.
  • All of the aforementioned metering devices may be electronic metering devices an electronic dosing system in the sense of this application.
  • they have a drive device with an electric drive for driving the displacement device.
  • They also have one electronic control and / or regulating device, in particular for the Drive, which is an electric drive motor, an electric linear drive or one of those mentioned in connection with microdosing devices Can be drives.
  • They also have an electrical power source for supplying control and / or regulating device and drive, the can be rechargeable.
  • Electronic dosing devices have the advantage the high reproducibility of doses. In particular, by default Dosing speeds ( ⁇ l / s) can produce more accurate results be considered with manually powered devices. Besides, they can do the Advantage of multifunctionality, since they have pipetting, dispensing, titration, Can perform mixed etc. functions.
  • the well-known electronic Handdosiervortechnischen Response® the Applicant work according to the air-cushion principle and work in single-channel or multi-channel version available.
  • This metering device can be in different Operating modes, i.a. pipette and dispense.
  • the Dispensing is possible in up to 25 steps.
  • the user can choose between three different dosing speeds.
  • the dosing device is used to charge the battery cells in a charging station.
  • EP 0 864 364 A2 is a similar electronic hand metering device with rechargeable batteries and a charging station for charging them known.
  • the manual dosing device can be in different Operate modes other than pipetting and dispensing include a hands-free operation. In it, the hand-dose device becomes like this programmed them to suck in, output and time delays for exchanging or treating the dosing tip controls. She leads this Program steps over a predetermined number of cycles.
  • the prior art electronic Handdosiervoriquesen have the Disadvantage that the specific operating parameters (eg step sizes of the Piston feeds, dosing speeds, state of charge criteria, display outputs) and the program are fixed.
  • the electronic Namely control means comprises a microcomputer, which after a fixed stored program works in which these parameters are included.
  • each model requires special software and one Subsequent change of parameters hardly possible.
  • Dosing devices are test equipment in the sense of the GLP (Good Laboratory Practice) guidelines and comparable QS standards (ISO 9000 ff, EN 45000 ff). According to the GLP guidelines, those published by the manufacturer Error limits are checked at regular intervals. By the applicant, a system has become known, with which the Calibration of dosing devices fast, convenient and cost-effective can accomplish.
  • This system is based on a calibration software PICASO®, which is based on a PC is running.
  • a measuring structure, the weighing vessels, Adapters and carrier sleeves and an evaporation trap and a Semi-microbalance included.
  • All relevant data are to testing dosing devices deposited. Deviations from these nominal values after transfer of the weighing values to the computer immediately determined.
  • a series of measurements covers up to 15 individual weighings. It will become Mean, inaccuracy, imprecision and standard deviation and compared with predetermined setpoints. All measurement and reference data can be logged in accordance with GLP-DIN.
  • From US 5,343,769 A is a method for filling and emptying a Pipette with quantitative accuracy known in which of a Piston traveled distance measured during the movement of the piston and the piston is stopped when a path corresponding to the desired Amount of liquid to be transferred has been reached. Further is from this document a pipette with elements for measuring the piston stroke and elements for controlling the movements of the piston.
  • the Pipette has a data input device, such as a keyboard, a display and an interface.
  • the data input device is used to supply the Control device with data or commands.
  • the display is for display the entered data and / or the steps performed.
  • the interface allows the controller connected to an external device to become, for example for data transmission or data processing.
  • the invention is based on the object, a method to provide an electronic dosing system in which the Influencing of Programs is improved.
  • Dosing provided for performing the method become.
  • the program the program-controlled electronic control and / or regulating device inscribed in the read-write memory and possibly read out of this. That's what the memory is for prefers a flash memory of a processor.
  • a processor with flash memory has implemented a proprietary program, the for communication via an interface, initiate the communication can. This makes it possible, in each Handdosiervoriques a partial or completely different program from the outside via the data interfaces or to change the program in whole or in part.
  • parameters may be device type specific parameters, especially those that intended for the performance of operations.
  • This can be the movement of the piston of a displacement device determining parameters (eg acceleration characteristics, piston velocity, Driving force, holding torque).
  • quantity determining parameters eg basic values and Limit values of dosing quantities, possible numbers of dosing steps, overspill volume for the discharge of residual liquid.
  • parameters can be the monitoring of operating states (eg evaluation criteria for the state of charge of an accumulator, for the operation of a limit switch or for the duration of a rest break for shutdown in a "sleep state").
  • operating states eg evaluation criteria for the state of charge of an accumulator, for the operation of a limit switch or for the duration of a rest break for shutdown in a "sleep state"
  • parameters can be an identification of the device, an identification code for a stored parameter set, etc.
  • User parameters are data that can also be manually entered by the user via a Keyboard of the manual dosing device can be entered. For this In particular, the dosing volume, dosing rates, etc. Further application parameters relate to the calibration of the manual dosing device. In a simple case, this may be a correction factor to convert the set dosing to the actual act dispensed dosing. This can especially Coefficients of a function will be the deviation of the set of the actually dispensed dosage at different volume settings includes.
  • a remote control the Handdosiervorraum possible.
  • the data processing system the respective Log dosing data. If necessary this can be done together with the respective measured values happen, if they are detected and in the data processing system be recorded.
  • a wired or a wireless remote control of Hand metering done. This favors in particular an automation dosing operations, the use of hand dosing in a higher-level automation process or safe dosing in contaminated environment.
  • the invention enables the specific parameters of the metering device only after the device assembly, even if they are the Installation of a module with permanently programmed software.
  • This makes it possible for different device models one and the same Software and electronics hardware to use.
  • the respective ones Parameters can be set or even changed as needed.
  • Due to the storability of user parameters by means of an external data processing system is a additional advantageous operating option created.
  • the service will have a light update to new operating parameters allows.
  • the OEM customer can in turn set a parameter for Carry out special OEM dosing parts.
  • the user gets the GLP parameter documentation facilitated and a simplified calibration with PC software. He also gets involved in automation processes facilitates and allows remote control.
  • the data interfaces of Handdosiervoriques and the data transfer device can be connected with each other temporarily or permanently. It can be data interfaces that are only linked together can be when the Handdosiervorsch in the data transfer device is used. The data interfaces can also be independent be connected with each other, whether the manual dosing in the Data transfer device is used.
  • the data interfaces of Handdosiervoriques and the data transfer device can communicate with each other through radio transmitters and Radio receiver be connected. Also, the data interfaces can work together have communicating IR transmitter and IR receiver. hereby becomes a permanent connection of the data interfaces or a wireless remote control favors. In addition or instead, the Data interfaces have interconnectable electrical contacts, by inserting the Handdosiervoroplasty in the data transfer device can be connected.
  • the electronic control device has a microcomputer, in particular a microcontroller.
  • the data transfer device can be connected to a separate data processing system, for example with a PC, or an integrated data processing system have, in particular a microcomputer or Mikrocontoller.
  • the electronic control and / or regulating device and / or the data processing system can usual input and output and memory devices including an exchangeable storage medium.
  • an exchangeable storage medium On the removable storage medium, a program for the Remote control and / or the calibration of Handdosiervorraum available be. This favors the equipment of the dosing system with software as needed and updating it.
  • the manual dosing device can work independently of the mains. Especially it may be provided with a rechargeable voltage source, for example one or more batteries.
  • a rechargeable voltage source for example one or more batteries.
  • she can be one with the rechargeable voltage source and can have connected charging interface the data transfer device is a charging part for charging the power source and a charging interface connected to the charging member for connecting having the charging interface of Handdosiervorraum.
  • the Charge interfaces of Handdosiervorraum and the data transfer device can have cooperative electrical charging contacts. These can coincide with the contacts of the data interfaces.
  • the Data transmission can in particular on the charging voltage or the charging current the loading part done. By modulation of the charging voltage or the Charge current can be on the same physical channel data transfer will be realized.
  • the data transfer device can be designed as a stationary device.
  • the hand-dose device can also be used as a stationary Device or used as a metering machine, when in the data transfer device is used. Then the power supply of the Hand metering be ensured on the charger.
  • the electronic hand-metering device is substantially from six functional areas, namely a drive device 1, a displacement device 2, an electronic control and / or Control device 3, an electrical voltage source 4, an operating device 5 and a display device 6.
  • the drive device 1 has an electric drive motor which is designed as a stepping motor 7.
  • the stepping motor 7 is an axis. 8 linearly displaceable back and forth.
  • the drive device an engine stage in the form of two H-bridges 9, the driving the stepping motor 7 is used. This comprises in a known to the expert Way eight power transistors connected in H-arrangement, with which the Stepper motor 7 via supply lines 10 in the forward and reverse directions can be operated.
  • the displacement device 2 has a piston 11 which on the axis 8 is fixed.
  • the piston 11 is displaceable in a cylinder 12. This is connected via a channel 13 with a metering tip 14, which from the device is separable.
  • the electronic control and / or regulating device 3 includes a microcontroller 15, in particular a timer, a working memory and a integrated non-volatile memory.
  • the microcontroller controls the H-bridges via control lines 16.
  • the electronic control and / or regulating device 3 includes a bidirectional serial interface 17, the electrical sliding contacts 18 has and is connected via data lines 19 to the Mikrocontoller 15. Further This includes an EEPROM 20, which via data lines 21 to the Mikrocontoller 15 is connected.
  • the electronic control and / or regulating device 3 a boost converter 22 for generating the supply voltage of the Stepping motor 7, which feeds the H-bridges 9 via supply lines 23.
  • Control lines 24 connect the microcontroller 15 to the boost converter 22nd
  • Another component of the control and / or regulating device 3 is another Boost converter 25, the microcontroller 15 via other supply lines 26 supplied.
  • the axis 8 of the stepping motor 7 is associated with a limit switch 27, the is monitored via a control line 28 from the microcontroller 15 to to allow a zero point adjustment.
  • the electrical voltage source 4 comprises two NiMH batteries 29, whose Supply voltage via feed lines 30 the boost converter 22 and the further boost converter 25 is supplied.
  • the supply voltage of the two Batteries 29 is supplied via control lines 31 to the microcontroller 15.
  • part of the electrical voltage source 4 is a charging current control 32, on the one hand via charging contacts 33, which serve as sliding contacts are executed, is connectable to an external power source and on the other hand is connected via charging lines 34 to the battery 29.
  • the charging current control 32 is also on control lines 35 for the charging voltage and via charging current control lines 36 each to the microcontroller 15th connected.
  • the operating device 5 comprises an input keyboard 37, which via lines 38 is connected to the microcontroller 15. It also includes release buttons 39, which is connected via lines 40 to the microcontroller 15.
  • the display device 6 is an LCD display, which via lines 41 with the microcontroller 15 is connected, which contains a display control
  • the control software is stored in the microcontroller 15. Dosing data can entered before a dosing by means of the input keyboard 37 become. By means of the shutter buttons 39 individual dosing can be triggered.
  • the display 6 shows input data, control commands and operating states the Handdosiervorraum 42 on.
  • the total supply voltage of the two battery cells 29 is 2.4 volts. These from the further boost converter 25 to 3.3 volts supply voltage regulated for the microcontroller 15.
  • the boost converter switches 22, the supply voltage of the battery 29 as a supply voltage the supply lines 23 by or increased to 6 or 8 volts.
  • the microcontroller 15 the operation of the stepping motor 7 via the control lines 16 controls, he knows its respective voltage requirements and controls the boost converter 22 accordingly.
  • the supply voltage is from the microcontroller 15 via the control lines 31 controlled. If it jumps below a permissible value, the display will show 6 a corresponding information issued.
  • a charge of the Batteries 29 take place.
  • the charging current control lines 36 the charging current in accordance with the charge state determined via the control lines 31 the battery 29 controlled.
  • Hand dosing devices 42 of the above type come - in part slightly modified - used in the dosing systems discussed below.
  • a manual dosing device 42 ' operates with a charging station 43 'together.
  • the serial interface 17 includes a RF transmitter and receiver coupled to an antenna 45.
  • the Charging station 43 ' has a corresponding RF transmitter and receiver 46th and an associated antenna 47 for radio communication with the Hand metering device 42 'on
  • the RF transmitter and receiver 46 is via a serial interface 48 of Charging station 43 connected to an external PC 49.
  • This configuration allows charging of the accumulators 29 by Inserting the manual dosing 42 'in the charging station 43'.
  • About the Radio communication between the antennas 45, 47 may be data between the PC 49 and the hand dispenser 42 'are exchanged, both when the Handdosiervoriques 42 'is inserted into the charging station 43' as even if it is spatially separated from it.
  • the PC 49 can Operating parameters, routines, programs or program parts in the EEPROM 20 of the manual dosing 42 enrolled and possibly from this be read out. Also, by means of the PC 49 is a remote control of Manual dosing 42 'possible.
  • the data interface 17 an IR transmitter 49 and an IR receiver 50.
  • Deviation includes the data interface 46 of the charging station 43 "an IR receiver 51 and an IR transmitter 52.
  • a manual dosing device 42 according to FIG. 1 is used.
  • the charging contacts 43 thereof are in turn charging contacts 44 of Charging station 43 assigned.
  • the electrical contacts 18 of the data interface 17 are electrical contacts 53 of the data interface 46 of the charging station 43 assigned.
  • the embodiment according to FIG. 5 differs from that according to FIG. 4 in that the charging station 43 '' 'is an integrated microcontoller system 54 with a non-volatile memory 55 and a keyboard 56, a display 57, a serial interface 58 and a removable storage medium 59 having.
  • the removable storage medium 59 may be an EEPROM card, a SMART card, a FLASH card, a disk, etc.
  • the microcontoller system 54 can take over the functions of the PC 49. In particular, he can control the traffic to Handdosiervoriques 42, the triggering of metering functions of the manual dosing device 42, the storage of data in internal and external memories 55, 59, 20 of the charging station 43 '' 'and the Handdosiervoriques 42, the data input and triggering the manual dosing device 42 via the keyboard 56, the Display of data on the display 57 and communication with a external control (PC) via the serial interface 58 serve.
  • PC external control

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  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Stored Programmes (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Arrangements For Transmission Of Measured Signals (AREA)

Claims (24)

  1. Procédé pour la mise en oeuvre d'un système de dosage électronique, comprenant un dispositif de dosage manuel électronique (42) qui comporte
    un dispositif d'entraínement (1) à entraínement électrique (7)
    au moins un dispositif de déplacement (2) pour le dosage de liquide, entraínable par le dispositif d'entraínement (1),
    un dispositif de commande et/ou de réglage électronique (3) commandé par programme pour l'entraínement (7),
    au moins une mémoire de lecture/écriture (20) non volatile,
    une source de tension électrique (29) en particulier pour l'entraínement électrique (7) et le dispositif de commande et/ou de réglage électronique (3), et
    une interface de données (17) connectée au dispositif de commande et/ou de réglage électronique (3),
    et comprenant
    une installation externe de traitement de données (49), et
    un dispositif de transfert de données (43) qui comporte une interface de données (46) pour connecter l'interface de données (17) du dispositif de dosage (42) à l'installation de traitement de données (49),
    caractérisé en ce que des routines pour l'exécution de déroulements opérationnels du dispositif de dosage manuel (42) auxquelles recourt le dispositif de commande et/ou de réglage électronique (3), sont inscrites dans la mémoire à lecture/écriture (20) au moyen de l'installation de traitement de données (49) par l'intermédiaire des interfaces de données (17, 46).
  2. Procédé selon la revendication 1, dans lequel, au moyen de l'installation de traitement de données (49) par l'intermédiaire des interfaces de données (17, 46), des paramètres spécifiques du type de l'appareil et/ou de l'appareil et/ou des paramètres d'application sont additionnellement inscrits dans la mémoire de lecture/écriture (20) et/ou sont lus de celle-ci, et/ou le dispositif de dosage manuel (42) est apte à être télécommandé par l'installation de traitement de données (49).
  3. Procédé selon la revendication 1 ou 2, dans lequel les interfaces de données (17, 46) communiquent entre elles en étant reliées par contacts.
  4. Procédé selon l'une des revendications 1 à 3, dans lequel les interfaces de données (17, 46) communiquent entre elles sans fil.
  5. Procédé selon la revendication 5, dans lequel les interfaces de données (17, 46) communiquent entre elles par radio, par voie optique, de manière inductive et/ou capacitive.
  6. Système de dosage, approprié pour la mise en oeuvre du procédé selon l'une des revendications 1 à 5, comprenant un dispositif de dosage manuel électronique (42) qui comporte
    un dispositif d'entraínement (1) à entraínement électrique (7),
    au moins un dispositif de déplacement (2) pour le dosage de liquide, entraínable par le dispositif d'entraínement (1),
    un dispositif de commande et/ou de réglage électronique (3) commandé par programme pour l'entraínement électrique (7),
    au moins une mémoire de lecture/écriture (20) non volatile,
    une source de tension électrique (29) en particulier pour la entraínement électrique (7) et le dispositif de commande et/ou de réglage électronique (3), et
    une interface de données (17) connectée au dispositif de commande et/ou de réglage électronique (3),
    et comprenant
    une installation de traitement de données externe (49) et
    un dispositif de transfert de données (43) qui comporte une interface de données (46) pour connecter l'interface de données (17) du dispositif de dosage (42) à l'installation de traitement de données (49),
    caractérisé en ce que le dispositif de commande et/ou de réglage électronique (3) commandé par programme est agencé de telle façon que des routines pour l'exécution de déroulements opérationnels du dispositif de dosage manuel (42), auxquelles recourt le dispositif de commande et/ou de réglage électronique (3), peuvent être inscrites dans la mémoire à lecture/écriture (20) au moyen de l'installation de traitement de données (49) par l'intermédiaire des interfaces de données (17, 46).
  7. Système de dosage, approprié pour la mise en oeuvre du procédé selon l'une des revendications 1 à 5 et selon le préambule de la revendication 6, dans lequel les interfaces de données (17, 46) du dispositif de dosage (42) et du dispositif de transfert de données (43) comportent des émetteurs radio et des récepteurs radio et/ou des émetteurs (49, 52) et récepteurs (50, 51) infrarouges communiquant les uns avec les autres.
  8. Système de dosage, approprié pour la mise en oeuvre du procédé selon l'une des revendications 1 à 5 et selon le préambule de la revendication 6, en particulier selon la revendication 6 ou 7, dans lequel les interfaces de données (17, 46) du dispositif de dosage (42) et du dispositif de transfert de données (43) sont des interfaces de données série.
  9. Système de dosage, approprié pour la mise en oeuvre du procédé selon l'une des revendications 1 à 5 et selon le préambule de la revendication 6, en particulier selon l'une des revendications 6 à 8, dans lequel le dispositif de commande et/ou de réglage électronique (3) comprend un micro-ordinateur ou microcontrôleur (15).
  10. Système de dosage selon la revendication 9 dans lequel la mémoire à lecture/écriture non volatile est une mémoire flash du micro-ordinateur ou microcontrôleur.
  11. Système de dosage, approprié pour la mise en oeuvre du procédé selon l'une des revendications 1 à 5 et selon le préambule de la revendication 6, en particulier selon l'une des revendications 6 à 10, dans lequel l'installation de traitement de données (49) qui est connectée à l'interface de données (46) du dispositif de transfert de données (43) comprend un PC raccordé au dispositif de transfert de données (43).
  12. Système de dosage, approprié pour la mise en oeuvre du procédé selon l'une des revendications 1 à 5 et selon le préambule de la revendication 6, en particulier selon l'une des revendications 6 à 11, dans lequel l'interface de données (46) du dispositif de transfert de données (43) est connectée à une l'installation de traitement de données (54) intégrée dans le dispositif de transfert de données (43).
  13. Système de dosage selon la revendication 12 dans lequel l'installation de traitement de données (49, 54) contient un micro-ordinateur ou un microcontrôleur.
  14. Système de dosage, approprié pour la mise en oeuvre du procédé selon l'une des revendications 1 à 5 et selon le préambule de la revendication 6, en particulier selon l'une des revendications 6 à 13, dans lequel le dispositif de commande électronique (3) et/ou l'installation de traitement de données (49, 54) comprend une mémoire non volatile (20, 55) et/ou un clavier (37, 39; 56) et/ou un affichage (6, 57) et/ou une interface série (17, 58) et/ou un support d'enregistrement (59) interchangeable.
  15. Système de dosage, approprié pour la mise en oeuvre du procédé selon l'une des revendications 1 à 5 et selon le préambule de la revendication 6, en particulier selon l'une des revendications 6 à 14, dans lequel le dispositif de dosage manuel (42) comporte une interface de charge (33) reliée à une source de tension rechargeable (29), et le dispositif de transfert de données (43) comprend un élément de charge pour charger la source de tension (29) et une interface de charge (44) connectée à l'élément de charge pour la connexion à l'interface de charge (33) du dispositif de dosage manuel (42).
  16. Système de dosage selon la revendication 15 dans lequel le dispositif de dosage (42) et le dispositif de transfert de données (43) comportent respectivement des interfaces de charge (33, 44) et de données (17, 46) communes.
  17. Système de dosage selon la revendication 15 ou 16 dans lequel le dispositif de commande et/ou de réglage électronique (3) coopère avec un dispositif de commande de courant de charge (32) du dispositif de dosage (42) pour commander le courant de charge en fonction de l'état de charge de la source de tension (29).
  18. Système de dosage selon la revendication 17 dans lequel le dispositif de commande et/ou de réglage électronique (3) détermine l'état de charge par surveillance de la tension d'alimentation électrique de la source de tension (29).
  19. Système de dosage, approprié pour la mise en oeuvre du procédé selon l'une des revendications 1 à 5 et selon le préambule de la revendication 6, en particulier selon l'une des revendications 15 à 18, dans lequel le dispositif de transfert de données (43) comprend plusieurs interfaces de charge (44) pour la charge simultanée des sources de tension (29) de plusieurs dispositifs de dosage (42) et/ou de plusieurs interfaces de données (46) pour une communication simultanée avec les interfaces de données (17) de plusieurs dispositifs de dosage (42).
  20. Système de dosage selon l'une des revendications 15 à 19 dans lequel le dispositif de transfert de données (43) comprend au moins une interface de charge (44) pour une source de tension électrique rechargeable (29) pouvant être retirée du dispositif de dosage (42).
  21. Système de dosage selon l'une des revendications 15 à 20 dans lequel les interfaces de charge (33, 44) du dispositif de dosage (42) et du dispositif de transfert de données (43) et/ou de la source de tension amovible (29) comprennent des contacts de charge électrique aptes à être connectés les uns aux autres.
  22. Système de dosage pour la mise en oeuvre du procédé selon l'une des revendications 1 à 5 et selon le préambule de la revendication 6, en particulier selon les revendications 6 à 21, dans lequel le dispositif de dosage manuel (42) est indépendant du réseau.
  23. Système de dosage pour la mise en oeuvre du procédé selon l'une des revendications 1 à 5 et selon le préambule de la revendication 6, en particulier selon les revendications 6 à 22, dans lequel le dispositif de transfert de données est un appareil stationnaire.
  24. Système de dosage selon l'une des revendications 6 à 23 dans lequel, au moyen de l'installation de traitement des données (49) ou des interfaces de données, des paramètres spécifiques du type de l'appareil et/ou de l'appareil et/ou de l'utilisateur sont enregistrables dans la mémoire de lecture/écriture (20) et/ou lisibles de cette mémoire, et/ou le dispositif de dosage manuel (42) est apte à être télécommandé.
EP99120656A 1998-11-04 1999-10-19 Procédé d' opération d' un système de dosage électronique et système de dosage pour la mise en oeuvre du procédé Expired - Lifetime EP0999432B2 (fr)

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DE19850841A DE19850841A1 (de) 1998-11-04 1998-11-04 Verfahren zum Betreiben eines elektronischen Dosiersystems und Dosiersystem zur Durchführung des Verfahrens
DE19850841 1998-11-04

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DE102007010299A1 (de) 2007-03-02 2008-09-04 Eppendorf Ag Handpipettiervorrichtung
DE102010047826A1 (de) 2010-10-04 2012-04-05 Eppendorf Ag Elektronische Pipette
DE102010047828A1 (de) 2010-10-04 2012-04-05 Eppendorf Ag Laborgerät zum Behandeln von Flüssigkeiten
DE102010047829A1 (de) 2010-10-04 2012-04-05 Eppendorf Ag Mechanische Pipette
DE102010047126A1 (de) 2010-10-04 2012-04-05 Eppendorf Ag Pipette
DE102012102918A1 (de) 2012-04-03 2013-10-10 Eppendorf Ag Laborgerätesystem und Laborgerät zum Behandeln von Fluiden und Feststoffen sowie Verfahren zum Betreiben eines Laborgerätes
EP3539665A1 (fr) 2018-03-16 2019-09-18 Eppendorf AG Système de dosage de laboratoire électronique pour liquides et procédé de fonctionnement d'un système de dosage de laboratoire électronique pour liquides

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EP1452849B1 (fr) * 2003-02-27 2016-02-24 Mettler-Toledo GmbH Appareil et méthode pour la préparation et/ou la dilution de solutions au laboratoire
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DE102006028797A1 (de) * 2006-06-23 2007-12-27 Khs Ag Austauschbares Antriebssystem
DE102006032859A1 (de) * 2006-07-14 2008-01-17 Eppendorf Ag Elektronische Dosiervorrichtung zum Dosieren von Flüssigkeiten
US7540205B2 (en) 2007-09-17 2009-06-02 Viaflo Corp. Electronic pipettor
DE102009051654B4 (de) 2009-10-30 2013-01-03 Eppendorf Ag Dosiervorrichtung für Flüssigkeiten und Verfahren zum Dosieren von Flüssigkeiten
US9309898B2 (en) 2012-02-22 2016-04-12 King Nutronics Corporation Multi-fluid precision calibration pressure source
EP2698202A3 (fr) 2012-08-15 2017-07-19 Integra Biosciences AG Sample distribution system and process
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CH710350A2 (de) * 2014-11-10 2016-05-13 Chemspeed Tech Ag Dosiervorrichtung.
CN107847929B (zh) 2015-06-05 2020-08-11 米梅塔斯私人有限公司 微流体板
CH714486A1 (de) 2017-12-21 2019-06-28 Integra Biosciences Ag Probenverteilsystem und Verfahren zum Verteilen von Proben.
EP3851191A1 (fr) * 2020-01-17 2021-07-21 Eppendorf AG Procédé de fonctionnement d'une pipette à course de piston, pipette à course de piston, appareil et système de traitement des données

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DE102007010299A1 (de) 2007-03-02 2008-09-04 Eppendorf Ag Handpipettiervorrichtung
DE102007010299B4 (de) * 2007-03-02 2009-01-29 Eppendorf Ag Handpipettiervorrichtung
WO2012045415A1 (fr) 2010-10-04 2012-04-12 Eppendorf Ag Dispositif de laboratoire pour manipuler des liquides
DE102010047828A1 (de) 2010-10-04 2012-04-05 Eppendorf Ag Laborgerät zum Behandeln von Flüssigkeiten
DE102010047829A1 (de) 2010-10-04 2012-04-05 Eppendorf Ag Mechanische Pipette
DE102010047126A1 (de) 2010-10-04 2012-04-05 Eppendorf Ag Pipette
DE102010047826A1 (de) 2010-10-04 2012-04-05 Eppendorf Ag Elektronische Pipette
WO2012045417A2 (fr) 2010-10-04 2012-04-12 Eppendorf Ag Pipette électronique
WO2012045416A1 (fr) 2010-10-04 2012-04-12 Eppendorf Ag Pipette mécanique
WO2012045418A1 (fr) 2010-10-04 2012-04-12 Eppendorf Ag Pipette
WO2012045417A3 (fr) * 2010-10-04 2012-08-02 Eppendorf Ag Pipette électronique
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CN103249487B (zh) * 2010-10-04 2016-02-17 埃佩多夫股份公司 电子移液器
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EP3539665A1 (fr) 2018-03-16 2019-09-18 Eppendorf AG Système de dosage de laboratoire électronique pour liquides et procédé de fonctionnement d'un système de dosage de laboratoire électronique pour liquides

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EP0999432A2 (fr) 2000-05-10
DE59909898D1 (de) 2004-08-12
EP0999432A3 (fr) 2001-02-28
JP2000234948A (ja) 2000-08-29
US6778917B1 (en) 2004-08-17
DE19850841A1 (de) 2000-05-25
EP0999432B2 (fr) 2008-09-24

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