EP0999432B2 - Procédé d' opération d' un système de dosage électronique et système de dosage pour la mise en oeuvre du procédé - Google Patents
Procédé d' opération d' un système de dosage électronique et système de dosage pour la mise en oeuvre du procédé Download PDFInfo
- Publication number
- EP0999432B2 EP0999432B2 EP99120656A EP99120656A EP0999432B2 EP 0999432 B2 EP0999432 B2 EP 0999432B2 EP 99120656 A EP99120656 A EP 99120656A EP 99120656 A EP99120656 A EP 99120656A EP 0999432 B2 EP0999432 B2 EP 0999432B2
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- European Patent Office
- Prior art keywords
- proportioning
- data
- charging
- electronic control
- anyone
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
- B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
- B01L3/0227—Details of motor drive means
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/02—Identification, exchange or storage of information
- B01L2300/025—Displaying results or values with integrated means
- B01L2300/027—Digital display, e.g. LCD, LED
Definitions
- the invention relates to a method for operating an electronic dosing system with an electronic hand dosing device and to a dosing system for carrying out the method.
- Dosing devices are used in laboratories for dosing liquids. They are known in different versions. Dosing devices operating on the principle of the air cushion have an integrated piston-cylinder unit, by means of which an air column can be displaced in order to suck in and eject sample liquid into a dosing tip. In this case, the piston-cylinder unit does not come into contact with the liquid. Only the dosing tip, which is usually made of plastic, is contaminated and can be replaced after use.
- a syringe In direct displacement metering, however, a syringe is filled directly with sample liquid. Piston and cylinder of the syringe are so contaminated by the liquid, so that the syringe usually has to be replaced or cleaned by a new syringe before changing the liquid.
- the syringe is usually made of plastic.
- Microdosing devices may have a micromembrane pump and / or a free jet dispenser, wherein at least one of these components is designed microsystem technology, in particular in silicon, glass, plastic injection molding and / or plastic embossing technique.
- the dosage is achieved by deformation of a wall of a chamber which is filled with liquid.
- the electric drive for deforming the wall may be piezoelectric, thermoelectric, electromagnetic, electrostatic, electromechanical, magneto-restrictive, etc.
- Air-cushion, direct-displacement, piston-less and micro-metering devices may have a fixed or variable metering volume.
- a change in the metering volume is achieved by adjusting the displacement of the displacement device, d. H. the displacement of the piston or the degree of deformation of the balloon-like end portion or the chamber wall.
- Dispensers are dosing devices that can deliver a recorded volume of liquid repetitively in small quantities.
- All dosing devices can be designed as handsets.
- All of the aforementioned metering devices may be electronic metering devices of an electronic metering system in the sense of this application.
- they have a drive device with an electric drive for driving the displacement device.
- they have an electronic control and / or regulating device, in particular for the drive, which may be an electric drive motor, an electric linear drive or one of the drives mentioned in connection with microdosing devices.
- they have an electrical voltage source for supplying control and / or regulating device and drive, which can be rechargeable.
- Electronic metering devices have the advantage of high reproducibility of dosages.
- pre-set dosing speeds ( ⁇ / s) can achieve more accurate results than with manually driven devices.
- they can have the benefit of multi-functionality, as they can perform pipetting, dispensing, titration, mixing, etc. functions.
- Applicants' known electronic hand dispensers Response® operate on the air-cushion principle and are available in single-channel or multi-channel designs. Four models cover the dosing range from 0.5 ⁇ l to 5 ml.
- This metering device can operate in various modes, i.a. pipette and dispense. Dispensing is possible in up to 25 steps. The user can choose between three different dosing speeds.
- the metering device can be used for charging the battery cells in a charging station.
- EP 0 864 364 A2 discloses a similar electronic manual dosing device with rechargeable batteries and a charging station for charging them.
- the handheld dosing device may be operated in various modes including hands-free operation other than pipetting and dispensing.
- the manual dosing device is programmed to control the aspiration, dispensing, and time delays to exchange or treat the dosing tip. It executes these program steps over a specified number of cycles.
- the previously known electronic manual dosing devices have the disadvantage that the specific operating parameters (eg step widths of the piston feed, metering speeds, state of charge criteria, display outputs) and the program are predefined.
- the electronic control device comprises a microcomputer which operates according to a permanently stored program in which these parameters are contained.
- a special software is required for each model and a subsequent change of the parameters hardly possible.
- the programming of the freehand operation must be carried out laboriously on the keyboard of the manual dosing and that in the freehand mode, the programmed steps are executed rigidly and the operation is not influenced.
- Dosing devices are test equipment within the meaning of the GLP (Good Laboratory Practice) guidelines and comparable QA standards (ISO 9000 ff, EN 45000 ff). According to the GLP guidelines, the error limits published by the manufacturer must be checked at regular intervals. By the applicant, a system has become known, with which the calibration of metering devices can be done quickly, conveniently and inexpensively.
- This system is based on a calibration software PICASO®, which runs on a PC.
- a measuring structure is required, which includes weighing containers, adapters and carrier sleeves as well as an evaporation trap and a semi-microbalance. All relevant data of the dosing devices to be tested are stored in the software. Deviations from these nominal values are determined immediately after transfer of the weighing values to the computer. A series of measurements covers up to 15 individual weighings. From this mean value, incorrectness, imprecision and standard deviation are determined and compared with predetermined target values. All measurement and reference data can be logged in accordance with GLP-DIN.
- the dosing data are entered and their operation is controlled via the control panel of the electronic manual dosing device.
- the weighing values are typed into the PC. This is troublesome and can lead to mistakes.
- a method for filling and emptying a pipette with quantitative accuracy in which the distance traveled by a piston path is measured during the movement of the piston and the piston is stopped when a distance corresponding to the desired amount of liquid has been achieved has been achieved.
- a pipette with elements for measuring the piston stroke and elements for controlling the movements of the piston is known.
- the pipette has a data input device, such as a keyboard, a display and an interface.
- the data input device serves to supply the control device with data or commands.
- the display is used to display the entered data and / or the steps performed.
- the interface allows the controller to be connected to an external device, for example for data transmission or data processing.
- the object of the invention is to provide a method for operating an electronic dosing system in which the ability to influence programs is improved.
- advantageous metering systems are to be provided for carrying out the method.
- the external data processing system can be used to access the read-write memory of the manual dosing device.
- routines for the execution of operating sequences in the read-write memory of the manual dosing device by means of the external data processing system so that the program-controlled electronic control and / or regulating device makes use of it.
- routines can be created by the user and serve to control operations composed of multiple operations, especially if they are to be repeated. For example, by means of such a "short program" it is possible to control the picking, mixing and dispensing of specific quantities of liquid or a series of dilutions in which the dispensing volume dispensed is halved from one dilution step to the next. This facilitates the use of routines for the user.
- the memory is preferably a flash memory of a processor.
- a flash memory processor has implemented a proprietary program that can initiate communication for data exchange over an interface. This makes it possible to load a partially or completely different program from the outside via the data interfaces into each hand-dose device or to change the program completely or partially.
- These may be device-type-specific parameters, in particular those that are intended for carrying out operating procedures.
- these may be the parameters of the movement of the piston of a displacement device (eg acceleration characteristic, piston speed, driving force, holding torque).
- these may be, for example, quantity-determining parameters (for example: basic values and limit values of metered quantities, possible numbers of metering steps, overspill volume for discharging residual liquid).
- other device-type specific parameters may relate to the monitoring of operating conditions (eg, evaluation criteria for the state of charge of an accumulator, for the actuation of a limit switch or for the duration of a rest in order to switch off to a "sleep state").
- Device-specific parameters can be, in particular, an identification of the device, an identification code for a respectively stored parameter set, etc.
- User parameters are data that can also be input manually by the user via a keyboard of the manual dosing device. These include, in particular, the metering volume, metering rates, etc. Further application parameters relate to the calibration of the manual metering device. In a simple case, this may be a correction factor for the conversion of the set dosing amounts to the actually dispensed dosing quantities. In particular, these may also be coefficients of a function which includes the deviation of the set metering quantities actually delivered with different quantity settings.
- a remote control of the manual dosing device is possible.
- This favors, in particular, the calibration by transferring the respective dosing data to the manual dosing device by means of the data processing system and, if appropriate, by completely controlling the operation by means of the data processing system.
- the data processing system can log the respective dosing data. Optionally, this can be done together with the respective measured values, if they are detected and recorded in the data processing system.
- a wired or a wireless remote control of the manual dosing device take place. This favors, in particular, an automation of the dosing operations, the use of the manual dosing device in a higher-level automation process or a safe dosing in a contaminated environment.
- the invention makes it possible to determine the specific parameters of the metering device only after the device assembly, even if this includes the installation of a block with permanently programmed software. This makes it possible to use the same software and electronic hardware for different device models.
- the respective parameters can be set as required or even changed.
- a device-type-specific or device-specific definition or modification of program parts or of the entire program is possible.
- the storability of user parameters by means of an external data processing system creates an additional, advantageous operating option.
- the invention favors automation of calibration and final inspection in manufacturing. The service will be able to easily update to new operating parameters.
- the OEM customer can in turn carry out a parameterization for special OEM metering parts. The user is facilitated the GLP parameter documentation and a simplified calibration with a PC software is made possible. It also facilitates integration into automation processes and enables remote control.
- the data interfaces of the manual dosing device and the data transfer device may be interconnected temporarily or permanently. It may be data interfaces that can only be connected to each other when the hand-held dosing device is inserted into the data transfer device. However, the data interfaces can also be connected to one another independently of whether the manual dosing device is inserted in the data transfer device.
- the data interfaces of the manual dosing device and the data transfer device may be connected by radio transmitters and radio receivers communicating with each other. Also, the data interfaces may include communicating IR transmitters and IR receivers. This promotes a permanent connection of the data interfaces or a wireless remote control. In addition or instead, the data interfaces may have interconnectable electrical contacts that may be connectable by inserting the handheld dosing device into the data transfer device.
- the electronic control device a microcomputer, in particular a microcontroller on.
- the data transfer device can be connected to a separate data processing system, for example with a PC, or have an integrated data processing system, in particular a microcomputer or Mikrocontoller
- the electronic control and / or regulating device and / or the data processing system may have conventional input and output and memory devices, including an exchangeable storage medium.
- a program for the remote control and / or the calibration of the manual dosing device can be present on the exchangeable storage medium. This favors the equipment of the dosing system with software as needed and their update.
- the manual dosing device can work independently of the mains.
- it may be provided with a rechargeable voltage source, for example one or more rechargeable batteries.
- the data transfer device may comprise a charging part for charging the voltage source and a charging interface connected to the charging part for connecting to the charging interface of the hand metering device.
- the charging interfaces of the hand-held meter and the data transfer device may have cooperating electrical charging contacts. These can coincide with the contacts of the data interfaces.
- the data transmission can be carried out in particular on the charging voltage or the charging current of the charging part. By modulating the charging voltage or charging current, data transmission can be realized on the same physical channel.
- the data transfer device can be designed as a stationary device.
- the manual dosing device can also be used as a stationary device or as a dosing machine when it is inserted into the data transfer device. Then the power supply of the manual dosing device can be ensured via the charging part.
- the electronic hand-held meter essentially consists of six functional areas, namely a drive device 1, a displacement device 2, an electronic control and / or regulating device 3, an electrical voltage source 4, an operating device 5 and a display device 6.
- the drive device 1- has an electric drive motor, which is designed as a stepping motor 7. By means of the stepping motor 7, an axis 8 is linearly displaceable back and forth.
- the drive device includes an engine stage in the form of two H-bridges 9, which serves to control the stepping motor 7. This includes, in a manner known to those skilled in eight H-connected power transistors with which the stepper motor, 7 can be operated via supply lines 10 in the forward and reverse directions.
- the displacement device 2 has a piston 11 which is fixed to the axis 8.
- the piston 11 is displaceable in a cylinder 12. This is connected via a channel 13 with a metering tip 14 which is separable from the device.
- the electronic control and / or regulating device 3 includes a microcontroller 15, which in particular has integrated a timer, a main memory and a nonvolatile memory.
- the microcontroller controls the H-bridges via control lines 16.
- the electronic control and / or regulating device 3 includes a bidirectional serial interface 17 which has electrical sliding contacts 18 and is connected to the microcontoller 15 via data lines 19. Furthermore, this includes an EEPROM 20, which is connected via data lines 21 to the microcontroller 15.
- the electronic control and / or regulating device 3 has an up-converter 22 for generating the supply voltage of the stepping motor 7, which feeds the H-bridges 9 via supply lines 23.
- Control lines 24 connect the microcontroller 15 to the boost converter 22.
- boost converter 25 Another component of the control and / or regulating device 3 is another boost converter 25 which supplies the microcontroller 15 via further supply lines 26.
- the axis 8 of the stepping motor 7 is associated with a limit switch 27 which is monitored by a control line 28 from the microcontroller 15 to allow a zero point adjustment.
- the electrical voltage source 4 comprises two NiMH batteries 29, whose supply voltage is fed via feed lines 30 to the up-converter 22 and the further boost converter 25.
- the supply voltage of the two batteries 29 is supplied via control lines 31 to the microcontroller 15.
- the electrical voltage source 4 includes a charging current control 32 which is connectable to an external power source via charging contacts 33, which are designed as sliding contacts, and is connected to the batteries 29 via charging lines 34.
- the charge current controller 32 is also connected to the microcontroller 15 via control lines 35 for the charging voltage and via charging current control lines 36, respectively.
- the operating device 5 comprises an input keyboard 37, which is connected via lines 38 to the microcontroller 15. It also includes release buttons 39, which is connected via lines 40 to the microcontroller 15.
- the display device 6 is an LCD display, which is connected via lines 41 to the microcontroller 15, which contains a display control
- the control software is stored in the microcontroller 15. Dosing data can be entered before dosing by means of the input keyboard 37. By means of the release buttons 39 individual dosing operations are triggered.
- the display 6 displays input data, control commands and operating states of the manual dosing device 42.
- the total supply voltage of the two battery cells 29 is 2.4 volts. This is regulated by the further boost converter 25 to 3.3 volts supply voltage for the microcontroller 15.
- the microcontroller 15 controls the operation of the stepper motor 7 via the control lines 16, it knows its respective voltage requirement and controls the boost converter 22 accordingly.
- the supply voltage is controlled by the microcontroller 15 via the control lines 31. If it jumps below a permissible value, the display 6 outputs a corresponding information.
- the charging contacts 33 By connecting the charging contacts 33 to an external power supply can be done in case of need, a charge of the battery 29.
- the charging current is controlled according to the determined via the control lines 31 state of charge of the battery 29.
- Manual dosing devices 42 of the above type are used - in some cases somewhat modified - in the dosing systems discussed below.
- a manual dosing device 42 cooperates with a charging station 43'.
- the charging contacts 33 of the manual dosing device 42 ' are associated with corresponding charging contacts 44 of the charging station 43.
- the RF transmitter and receiver 46 is connected to an external PC 49 via a serial interface 48 of the charging station 43.
- This configuration allows the accumulators 29 to be charged by inserting the hand meter 42 'into the charging station 43'.
- Data can be exchanged between the PC 49 and the manual dosing device 42 'via the radio connection between the antennas 45, 47, both when the manual dosing device 42' is inserted into the charging station 43 'and when it is spatially separated therefrom.
- the PC 49 operating parameters, routines, programs or program parts can be written into the EEPROM 20 of the manual dosing device 42 and possibly read out from this. Also, by means of the PC 49, a remote control of the manual dosing device 42 'possible.
- the hand-dose device 42 "and the charging station 43" again have connectable charging contacts 43, 44.
- the data interface 17 has an IR transmitter 49 and an IR receiver 50.
- the data interface 46 of the charging station 43 "comprises an IR receiver 51 and an IR transmitter 52.
- the PC 49 and the manual dosing device 42 can in turn exchange data, in principle both when the manual dosing device 42" is inserted into the charging station 43 °, and when they are outside of the same located.
- Fig. 4 comes a hand meter 42 according to Fig. 1 for use.
- Charging contacts 43 of the charging station 43 are in turn associated with the charging contacts 43 of the charging station 43.
- the electrical contacts 18 of the data interface 17 are associated with electrical contacts 53 of the data interface 46 of the charging station 43.
- the execution according to Fig. 5 differs from the according to Fig. 4 in that the charging station 43 "'has an integrated micro-controller system 54 with a non-volatile memory 55 and a keyboard 56, a display 57, a serial interface 58 and a removable storage medium 59.
- the removable storage medium 59 may be an EEPROM card, a SMART Card, a FLASH card, a disk, etc.
- the handheld dosing device 42 can control the data traffic to the handheld dosing device 42, initiate dosing functions of the hand dosing device 42, store data in internal and external memories 55, 59, 20 of the charging station 43 "'and the hand-held dosing device 42, the data input and release of the Häriddosienrorcardi 42 via the keyboard 56, the display of data on the display 57 and the communication with an external controller (PC) via the serial interface 58 are used.
- PC external controller
Claims (24)
- Procédé pour exploiter un système de dosage électronique avec- un dispositif de dosage manuel électronique (42), présentant- un dispositif d'entraînement (1) présentant un entraînement électrique (7),- au moins un dispositif de refoulement (2) pouvant être entraîné par le dispositif d'entraînement (1) pour le dosage de liquide, dans lequel le dispositif de refoulement présente un piston (11) mobile dans un cylindre (12) pour déplacer une colonne d'air et le cylindre est relié à travers un canal (13) à un cône de dosage (14) pour aspirer un liquide d'échantillonnage dans le cône de dosage et l'expulser hors de celui-ci, ou le dispositif de refoulement est une seringue présentant un piston et un cylindre et étant remplie directement avec un liquide d'échantillonnage,- un dispositif de commande et/ou de régulation électronique programmable (3) pour l'entraînement (7),- au moins une mémoire d'écriture/lecture non volatile (20),- une source de tension électrique (29) en particulier pour l'entraînement électrique (7) et le dispositif de commande et/ou de régulation électronique (3), et- une interface de données (17) reliée au dispositif de commande et/ou de régulation électronique,avec- un équipement informatique externe (49),et avec- un dispositif de transfert de données (43), présentant- une interface de données (46) pour relier l'interface de données (17) du dispositif de dosage (42) à l'équipement informatique (49),caractérisé en ce qu'au moyen de l'équipement informatique (49), à travers les interfaces de données (17, 46)- des routines pour l'exécution de séquences d'opérations du dispositif de dosage manuel (42), auxquelles le dispositif de commande et/ou de régulation électronique programmable (3) fait appel, sont écrites dans la mémoire d'écriture/lecture (20).
- Procédé selon la revendication 1, dans lequel au moyen de l'équipement informatique (49), à travers les interfaces de données (17, 46), en plus des paramètres spécifiques au type d'appareil et/ou des paramètres spécifiques à l'appareil et/ou des paramètres d'application sont écrits dans la mémoire d'écriture/lecture (20) et/ou sont lus à partir de celle-ci et/ou le dispositif de dosage manuel (42) peut être télécommandé.
- Procédé selon la revendication 1 ou 2, dans lequel les interfaces de données (17, 46) communiquent ensemble par contact.
- Procédé selon l'une quelconque des revendications 1 à 3, dans lequel les interfaces de données (17, 46) communiquent ensemble sans fil.
- Procédé selon la revendication 5, dans lequel les interfaces de données (17, 46) communiquent ensemble par radiocommunication, de façon optique, de façon inductive et/ou de façon capacitive.
- Système de dosage, adapté pour exécuter le procédé selon l'une quelconque des revendications 1 à 5, avec- un dispositif de dosage manuel électronique (42), présentant- un dispositif d'entraînement (1) présentant un entraînement électrique (7),- au moins un dispositif de refoulement (2) pouvant être entraîné par le dispositif d'entraînement (1) pour le dosage de liquide, dans lequel le dispositif de refoulement présente un piston (11) mobile dans un cylindre (12) pour déplacer une colonne d'air et le cylindre est relié à travers un canal (13) à un cône de dosage (14) pour aspirer un liquide d'échantillonnage dans le cône de dosage et l'expulser hors de celui-ci, ou le dispositif de refoulement est une seringue présentant un piston et un cylindre et étant remplie directement avec un liquide d'échantillonnage,- un dispositif de commande et/ou de régulation électronique programmable (3) pour l'entraînement (7),- au moins une mémoire d'écriture/lecture non volatile (20),- une source de tension électrique (29) en particulier pour l'entraînement électrique (7) et le dispositif de commande et/ou de régulation électronique (3), et- une interface de données (17) reliée au dispositif de commande et/ou de régulation électronique,avec- un équipement informatique externe (49),et avec- un dispositif de transfert de données (43), présentant une interface de données (46) pour relier l'interface de données (17) du dispositif de dosage (42) à l'équipement informatique (49),caractérisé en ce que- le dispositif de commande et/ou de régulation électronique programmable (3) est conçu de telle sorte qu'au moyen de l'équipement informatique (49), à travers les interfaces de données (17, 46), des routines pour l'exécution de séquences d'opérations du dispositif de dosage manuel (42), auxquelles le dispositif de commande et/ou de régulation électronique programmable (3) fait appel, peuvent être écrites dans la mémoire d'écriture/lecture (20).
- Système de dosage adapté pour exécuter le procédé selon l'une quelconque des revendications 1 à 5 selon le préambule de la revendication 6, dans lequel les interfaces de données (17, 46) du dispositif de dosage (42) et du dispositif de transfert de données (43) comportent des émetteurs radio et des récepteurs radio et/ou des émetteurs IF (49, 52) et des récepteurs IF (50, 51).
- Système de dosage adapté pour exécuter le procédé selon l'une quelconque des revendications 1 à 5 selon le préambule de la revendication 6, en particulier selon la revendication 6 ou 7, dans lequel les interfaces de données (17, 46) du dispositif de dosage (42) et du dispositif de transfert de données (43) sont des interfaces de données série.
- Système de dosage adapté pour exécuter le procédé selon l'une quelconque des revendications 1 à 5 selon le préambule de la revendication 6, en particulier selon l'une quelconque des revendications 6 à 8, dans lequel le dispositif de commande et/ou de régulation électronique (3) présente un micro-ordinateur ou un microcontrôleur (15).
- Système de dosage selon la revendication 9, dans lequel la mémoire d'écriture/lecture non volatile est une mémoire flash du micro-ordinateur ou du microcontrôleur.
- Système de dosage adapté pour exécuter le procédé selon l'une quelconque des revendications 1 à 5 selon le préambule de la revendication 6, en particulier selon l'une quelconque des revendications 6 à 10, dans lequel l'équipement informatique (49) relié à l'interface de données (46) du dispositif de transfert de données (43) présente un PC connecté au dispositif de transfert de données (43).
- Système de dosage adapté pour exécuter le procédé selon l'une quelconque des revendications 1 à 5 selon le préambule de la revendication 6, en particulier selon l'une quelconque des revendications 6 à 11, dans lequel l'interface de données (46) du dispositif de transfert de données (43) est reliée à un équipement informatique (54) intégré dans le dispositif de transfert de données (43).
- Système de dosage selon la revendication 12, dans lequel l'équipement informatique (49, 54) comprend un micro-ordinateur ou un microcontrôleur.
- Système de dosage adapté pour exécuter le procédé selon l'une quelconque des revendications 1 à 5 selon le préambule de la revendication 6, en particulier selon l'une quelconque des revendications 6 à 13, dans lequel le dispositif de commande électronique (3) et/ou l'équipement informatique (49, 54) présentent une mémoire non volatile (20, 55) et/ou un clavier (37, 39 ; 56) et/ou un affichage (6, 57) et/ou une interface série (17, 58) et/ou un support de mémoire échangeable (59).
- Système de dosage adapté pour exécuter le procédé selon l'une quelconque des revendications 1 à 5 selon le préambule de la revendication 6, en particulier selon l'une quelconque des revendications 6 à 14, dans lequel le dispositif de dosage manuel (42) comporte une interface de charge (33) reliée à une source de tension rechargeable (29) et le dispositif de transfert de données (43) comporte un chargeur pour recharger la source de tension (29) et une interface de charge (44) reliée au chargeur (43) pour la connexion avec l'interface de charge (33) du dispositif de dosage manuel (42).
- Système de dosage selon la revendication 15, dans lequel le dispositif de dosage (42) et le dispositif de transfert de données (43) comportent respectivement des interfaces de charge (33, 44) et de données (17, 46) communes.
- Système de dosage selon l'une des revendications 15 ou 16, dans lequel le dispositif de commande et/ou de régulation électronique (3) coopère avec une commande de courant de charge (32) du dispositif de dosage (42) pour commander le courant de charge selon l'état de charge de la source de tension (29).
- Système de dosage selon la revendication 17, dans lequel le dispositif de commande et/ou de régulation électronique (3) détermine l'état de charge par surveillance de la tension d'alimentation électrique de la source de tension (29).
- Système de dosage pour exécuter le procédé selon l'une quelconque des revendications 1 à 5 selon le préambule de la revendication 6, en particulier selon l'une quelconque des revendications 15 à 18, dans lequel le dispositif de transfert de données (43) présente plusieurs interfaces de charge (44) pour recharger simultanément les sources de tension (29) de plusieurs dispositifs de dosage (42) et/ou plusieurs interfaces de données (46) pour communiquer simultanément avec les interfaces de données (17) de plusieurs dispositifs de dosage (42).
- Dispositif de dosage selon l'une quelconque des revendications 15 à 19, dans lequel le dispositif de transfert de données (43) présente au moins une interface de charge (44) pour une source de tension électrique (29) rechargeable, extractible du dispositif de dosage (42).
- Système de dosage selon l'une quelconque des revendications 15 à 20, dans lequel les interfaces de charge (33, 44) du dispositif de dosage (42) et du dispositif de transfert de données (43) et/ou de la source de tension extractible (29) présentent des contacts de charge électriques pouvant être reliés ensemble.
- Système de dosage pour exécuter le procédé selon l'une quelconque des revendications 1 à 5 selon le préambule de la revendication 6, en particulier selon l'une quelconque des revendications 6 à 21, dans lequel le dispositif de dosage manuel (42) est indépendant du secteur.
- Système de dosage adapté pour exécuter le procédé selon l'une quelconque des revendications 1 à 5 selon le préambule de la revendication 6, en particulier selon l'une quelconque des revendications 6 à 22, dans lequel le dispositif de transfert de données est un appareil stationnaire.
- Système de dosage selon l'une quelconque des revendications 6 à 23, dans lequel, au moyen de l'équipement informatique (49) ou des interfaces de données, des paramètres spécifiques au type d'appareil et/ou des paramètres spécifiques à l'appareil et/ou des paramètres d'utilisateur peuvent être écrits dans la mémoire d'écriture/lecture (20) et/ou peuvent être lus à partir de celle-ci et/ou le dispositif de dosage manuel (42) peut être télécommandé.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19850841 | 1998-11-04 | ||
DE19850841A DE19850841A1 (de) | 1998-11-04 | 1998-11-04 | Verfahren zum Betreiben eines elektronischen Dosiersystems und Dosiersystem zur Durchführung des Verfahrens |
Publications (4)
Publication Number | Publication Date |
---|---|
EP0999432A2 EP0999432A2 (fr) | 2000-05-10 |
EP0999432A3 EP0999432A3 (fr) | 2001-02-28 |
EP0999432B1 EP0999432B1 (fr) | 2004-07-07 |
EP0999432B2 true EP0999432B2 (fr) | 2008-09-24 |
Family
ID=7886673
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP99120656A Expired - Lifetime EP0999432B2 (fr) | 1998-11-04 | 1999-10-19 | Procédé d' opération d' un système de dosage électronique et système de dosage pour la mise en oeuvre du procédé |
Country Status (4)
Country | Link |
---|---|
US (1) | US6778917B1 (fr) |
EP (1) | EP0999432B2 (fr) |
JP (1) | JP2000234948A (fr) |
DE (2) | DE19850841A1 (fr) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
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JP4672935B2 (ja) * | 2001-09-28 | 2011-04-20 | アロカ株式会社 | 分注装置 |
DE10239901A1 (de) * | 2002-08-30 | 2004-03-25 | Eppendorf Ag | Verfahren zum Handhaben von Daten einer Dosiervorrichtung und Dosiervorrichtung geeignet zur Durchführung des Verfahrens |
DE10307030A1 (de) * | 2003-02-20 | 2004-09-09 | Eppendorf Ag | Dosiersystem |
EP1452849B1 (fr) * | 2003-02-27 | 2016-02-24 | Mettler-Toledo GmbH | Appareil et méthode pour la préparation et/ou la dilution de solutions au laboratoire |
FR2862889B1 (fr) * | 2003-11-27 | 2006-09-22 | Gilson Sas | Pipette a main pour le prelevement d'un echantillon liquide sans derive de temperature |
US7976793B2 (en) | 2003-11-27 | 2011-07-12 | Gilson S.A.S. | Electronic pipette |
JP4719692B2 (ja) * | 2004-02-06 | 2011-07-06 | セヨニック エス.アー. | ピペット検査装置及びそれを取り付けたピペット |
FR2887982B1 (fr) * | 2005-07-01 | 2009-03-06 | Biomerieux Sa | Dispositif de pipetage automatique permettant de s'assurer de la tracabilite de l'analyse realisee |
DE102006028797A1 (de) * | 2006-06-23 | 2007-12-27 | Khs Ag | Austauschbares Antriebssystem |
DE102006032859A1 (de) * | 2006-07-14 | 2008-01-17 | Eppendorf Ag | Elektronische Dosiervorrichtung zum Dosieren von Flüssigkeiten |
DE102007010299B4 (de) | 2007-03-02 | 2009-01-29 | Eppendorf Ag | Handpipettiervorrichtung |
US7540205B2 (en) | 2007-09-17 | 2009-06-02 | Viaflo Corp. | Electronic pipettor |
DE102009051654B4 (de) | 2009-10-30 | 2013-01-03 | Eppendorf Ag | Dosiervorrichtung für Flüssigkeiten und Verfahren zum Dosieren von Flüssigkeiten |
DE102010047126A1 (de) | 2010-10-04 | 2012-04-05 | Eppendorf Ag | Pipette |
DE102010047828A1 (de) | 2010-10-04 | 2012-04-05 | Eppendorf Ag | Laborgerät zum Behandeln von Flüssigkeiten |
DE102010047829A1 (de) | 2010-10-04 | 2012-04-05 | Eppendorf Ag | Mechanische Pipette |
DE102010047826A1 (de) | 2010-10-04 | 2012-04-05 | Eppendorf Ag | Elektronische Pipette |
WO2013126343A2 (fr) | 2012-02-22 | 2013-08-29 | King Nutronics Corporation | Source de pression d'étalonnage de précision multifuide |
DE102012102918A1 (de) | 2012-04-03 | 2013-10-10 | Eppendorf Ag | Laborgerätesystem und Laborgerät zum Behandeln von Fluiden und Feststoffen sowie Verfahren zum Betreiben eines Laborgerätes |
EP2698202A3 (fr) | 2012-08-15 | 2017-07-19 | Integra Biosciences AG | Sample distribution system and process |
FR3002466A1 (fr) * | 2013-02-27 | 2014-08-29 | Gilson Sas | Pipette motorisee |
CH710350A2 (de) | 2014-11-10 | 2016-05-13 | Chemspeed Tech Ag | Dosiervorrichtung. |
US10532355B2 (en) | 2015-06-05 | 2020-01-14 | Mimetas B.V. | Microfluidic plate |
CH714486A1 (de) | 2017-12-21 | 2019-06-28 | Integra Biosciences Ag | Probenverteilsystem und Verfahren zum Verteilen von Proben. |
PL3539665T3 (pl) | 2018-03-16 | 2022-12-12 | Eppendorf Se | Elektroniczny laboratoryjny system dozowania cieczy oraz sposób działania elektronicznego laboratoryjnego systemu dozowania cieczy |
EP3851191A1 (fr) * | 2020-01-17 | 2021-07-21 | Eppendorf AG | Procédé de fonctionnement d'une pipette à course de piston, pipette à course de piston, appareil et système de traitement des données |
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US4333458A (en) * | 1981-02-09 | 1982-06-08 | Sterling Drug Inc. | Self-aspirating syringe with positively engaged locking collet |
US5187990A (en) * | 1984-02-16 | 1993-02-23 | Rainin Instrument Co., Inc. | Method for dispensing liquids with a pipette with compensation for air pressure and surface tension |
US4908017A (en) * | 1985-05-14 | 1990-03-13 | Ivion Corporation | Failsafe apparatus and method for effecting syringe drive |
KR870001472A (ko) * | 1985-07-05 | 1987-03-14 | 알버트 피. 할루인 | 자동 액체 처리 장치 및 그 방법 |
WO1987006008A2 (fr) * | 1986-03-26 | 1987-10-08 | Beckman Instruments, Inc. | Centre de traitement automatise multi-usages avec poste de travail en laboratoire pour chimie analytique |
US4810348A (en) * | 1987-03-16 | 1989-03-07 | Helena Laboratories Corporation | Automatic electrophoresis apparatus and method |
US4821586A (en) * | 1988-02-25 | 1989-04-18 | Medical Laboratory Automation, Inc. | Programmable pipette |
JPH0351760A (ja) * | 1989-07-19 | 1991-03-06 | Hitachi Ltd | 自動分析装置 |
FI87740C (fi) * | 1990-05-04 | 1994-04-08 | Biohit Oy | Pipett |
JPH0581034A (ja) * | 1991-08-03 | 1993-04-02 | Olympus Optical Co Ltd | 自動分析装置 |
JPH05126690A (ja) * | 1991-11-05 | 1993-05-21 | Tabai Espec Corp | 液体分注装置 |
WO1995002426A1 (fr) * | 1993-07-13 | 1995-01-26 | Sims Deltec, Inc. | Pompe medicale et procede de programmation de ladite pompe |
US5454268A (en) * | 1993-11-15 | 1995-10-03 | Kim; Young S. | Double-plunger liquid displacement syringe pipet |
CA2129284C (fr) * | 1993-11-24 | 1999-03-09 | Kenneth J. Niehoff | Regulation de l'entrainement du plongeur pour l'injection de liquides a des animaux |
DE69532045T2 (de) * | 1994-08-01 | 2004-07-08 | Abbott Laboratories, Abbott Park | Verfahren und Vorrichtung zur Vorbereitung einer Flüssigkeit |
US5602744A (en) * | 1994-09-29 | 1997-02-11 | Meek; Jean L. | Universal send/receive utility usage data gathering system |
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US6090348A (en) * | 1997-03-14 | 2000-07-18 | Becton, Dickinson And Company | Method for programming an electronic pipetter |
-
1998
- 1998-11-04 DE DE19850841A patent/DE19850841A1/de not_active Ceased
-
1999
- 1999-10-19 DE DE59909898T patent/DE59909898D1/de not_active Expired - Lifetime
- 1999-10-19 EP EP99120656A patent/EP0999432B2/fr not_active Expired - Lifetime
- 1999-11-01 US US09/431,457 patent/US6778917B1/en not_active Expired - Lifetime
- 1999-11-04 JP JP11313613A patent/JP2000234948A/ja active Pending
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Title |
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Also Published As
Publication number | Publication date |
---|---|
EP0999432B1 (fr) | 2004-07-07 |
EP0999432A2 (fr) | 2000-05-10 |
EP0999432A3 (fr) | 2001-02-28 |
DE59909898D1 (de) | 2004-08-12 |
US6778917B1 (en) | 2004-08-17 |
DE19850841A1 (de) | 2000-05-25 |
JP2000234948A (ja) | 2000-08-29 |
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