EP0913473A4 - Verfahren zur herstellung von eicosapentaensäure durch genetische rekombination - Google Patents

Verfahren zur herstellung von eicosapentaensäure durch genetische rekombination

Info

Publication number
EP0913473A4
EP0913473A4 EP97930728A EP97930728A EP0913473A4 EP 0913473 A4 EP0913473 A4 EP 0913473A4 EP 97930728 A EP97930728 A EP 97930728A EP 97930728 A EP97930728 A EP 97930728A EP 0913473 A4 EP0913473 A4 EP 0913473A4
Authority
EP
European Patent Office
Prior art keywords
genetic recombination
icosapentaenoic acid
producing
producing icosapentaenoic
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP97930728A
Other languages
English (en)
French (fr)
Other versions
EP0913473A1 (de
Inventor
Kazunaga Yazawa
Akiko Yamada
Kiyosi Kondo
Seishi Kato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sagami Chemical Research Institute
Original Assignee
Sagami Chemical Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sagami Chemical Research Institute filed Critical Sagami Chemical Research Institute
Publication of EP0913473A1 publication Critical patent/EP0913473A1/de
Publication of EP0913473A4 publication Critical patent/EP0913473A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6432—Eicosapentaenoic acids [EPA]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
EP97930728A 1996-07-10 1997-07-09 Verfahren zur herstellung von eicosapentaensäure durch genetische rekombination Withdrawn EP0913473A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP180845/96 1996-07-10
JP18084596 1996-07-10
PCT/JP1997/002371 WO1998001565A1 (fr) 1996-07-10 1997-07-09 Procede de production d'acide icosapentaenoique par recombinaison genetique

Publications (2)

Publication Number Publication Date
EP0913473A1 EP0913473A1 (de) 1999-05-06
EP0913473A4 true EP0913473A4 (de) 2000-12-06

Family

ID=16090370

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97930728A Withdrawn EP0913473A4 (de) 1996-07-10 1997-07-09 Verfahren zur herstellung von eicosapentaensäure durch genetische rekombination

Country Status (5)

Country Link
EP (1) EP0913473A4 (de)
AU (1) AU727694B2 (de)
CA (1) CA2259942A1 (de)
NO (1) NO990083L (de)
WO (1) WO1998001565A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6566583B1 (en) * 1997-06-04 2003-05-20 Daniel Facciotti Schizochytrium PKS genes
US7217856B2 (en) 1999-01-14 2007-05-15 Martek Biosciences Corporation PUFA polyketide synthase systems and uses thereof
CN103451246B (zh) 2004-04-22 2018-02-16 联邦科学技术研究组织 用重组细胞合成长链多不饱和脂肪酸
CA3023314C (en) 2004-04-22 2019-12-10 Commonwealth Scientific And Industrial Research Organisation Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
JP4943678B2 (ja) * 2005-08-01 2012-05-30 国立大学法人北海道大学 細胞の脂肪酸組成を改変する方法およびその利用
AU2007226511A1 (en) 2006-03-15 2007-09-20 Dsm Ip Assets B.V. Plant seed oils containing polyunsaturated fatty acids
WO2008025068A1 (en) 2006-08-29 2008-03-06 Commonwealth Scientific And Industrial Research Organisation Synthesis of fatty acids
EP3260544A1 (de) 2008-11-18 2017-12-27 Commonwealth Scientific and Industrial Research Organisation Enzyme und verfahren zur herstellung von omega-3-fettsäuren
EP2408797B1 (de) 2009-03-19 2017-03-15 DSM IP Assets B.V. Nukleinsäuremoleküle und polypeptide aus pufa-synthasen, zusammensetzungen und verfahren zu ihrer herstellung und verwendung
JP6242882B2 (ja) 2012-06-15 2017-12-06 コモンウェルス サイエンティフィック アンド インダストリアル リサーチ オーガナイゼーション 植物細胞における長鎖多価不飽和脂肪酸の産生
KR102535223B1 (ko) 2013-12-18 2023-05-30 커먼웰쓰 사이언티픽 앤 인더스트리알 리서치 오거니제이션 장쇄 다중불포화 지방산을 포함하는 지질
WO2015196250A1 (en) 2014-06-27 2015-12-30 Commonwealth Scientific And Industrial Research Organisation Lipid comprising docosapentaenoic acid

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998055625A1 (en) * 1997-06-04 1998-12-10 Calgene, Llc Production of polyunsaturated fatty acids by expression of polyketide-like synthesis genes in plants

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0761272B2 (ja) * 1986-12-26 1995-07-05 財団法人相模中央化学研究所 エイコサペンタエン酸含有脂質の製造方法
JPH0646864A (ja) * 1992-05-15 1994-02-22 Sagami Chem Res Center イコサペンタエン酸合成酵素群をコードする遺伝子及びイコサペンタエン酸の製造方法
JPH08242867A (ja) * 1995-01-13 1996-09-24 Sagami Chem Res Center イコサペンタエン酸生合成酵素群をコードする遺伝子及びイコサペンタエン酸の製造法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998055625A1 (en) * 1997-06-04 1998-12-10 Calgene, Llc Production of polyunsaturated fatty acids by expression of polyketide-like synthesis genes in plants

Also Published As

Publication number Publication date
NO990083L (no) 1999-03-04
NO990083D0 (no) 1999-01-08
AU727694B2 (en) 2000-12-21
EP0913473A1 (de) 1999-05-06
CA2259942A1 (en) 1998-01-15
AU3458397A (en) 1998-02-02
WO1998001565A1 (fr) 1998-01-15

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