EP0850057A4 - Composes pharmaceutiques - Google Patents
Composes pharmaceutiquesInfo
- Publication number
- EP0850057A4 EP0850057A4 EP96929780A EP96929780A EP0850057A4 EP 0850057 A4 EP0850057 A4 EP 0850057A4 EP 96929780 A EP96929780 A EP 96929780A EP 96929780 A EP96929780 A EP 96929780A EP 0850057 A4 EP0850057 A4 EP 0850057A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- pharmaceutical compounds
- pharmaceutical
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US293595P | 1995-08-30 | 1995-08-30 | |
US2935 | 1995-08-30 | ||
PCT/US1996/013855 WO1997007798A1 (fr) | 1995-08-30 | 1996-08-30 | Composes pharmaceutiques |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0850057A1 EP0850057A1 (fr) | 1998-07-01 |
EP0850057A4 true EP0850057A4 (fr) | 2001-04-11 |
Family
ID=21703268
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP96932217A Withdrawn EP0850316A4 (fr) | 1995-08-30 | 1996-08-30 | Cryptophycines obtenues a partir d'une biosynthese aberrante |
EP96929780A Withdrawn EP0850057A4 (fr) | 1995-08-30 | 1996-08-30 | Composes pharmaceutiques |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP96932217A Withdrawn EP0850316A4 (fr) | 1995-08-30 | 1996-08-30 | Cryptophycines obtenues a partir d'une biosynthese aberrante |
Country Status (6)
Country | Link |
---|---|
EP (2) | EP0850316A4 (fr) |
JP (2) | JP2000501067A (fr) |
AU (2) | AU709828B2 (fr) |
BR (1) | BR9610214A (fr) |
CA (2) | CA2246117A1 (fr) |
WO (2) | WO1997008334A1 (fr) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997008334A1 (fr) * | 1995-08-30 | 1997-03-06 | University Of Hawaii | Cryptophycines obtenues a partir d'une biosynthese aberrante |
DE69626544T2 (de) * | 1995-12-22 | 2004-01-15 | Lilly Co Eli | Arzneistoffe |
CZ64599A3 (cs) * | 1996-08-30 | 1999-10-13 | Eli Lilly And Company | Farmaceutické sloučeniny |
JP2001500484A (ja) * | 1996-08-30 | 2001-01-16 | イーライ・リリー・アンド・カンパニー | 医薬化合物の製造法 |
WO1998008506A1 (fr) * | 1996-08-30 | 1998-03-05 | Eli Lilly And Company | Composes pharmaceutiques |
US6680311B1 (en) | 1996-08-30 | 2004-01-20 | Eli Lilly And Company | Cryptophycin compounds |
WO1998009974A1 (fr) * | 1996-09-06 | 1998-03-12 | Eli Lilly And Company | Procede et nouveaux intermediaires |
HUP0000212A3 (en) * | 1996-09-06 | 2001-12-28 | Wayne State University Detroit | Process to prepare cryptophycin derivatives and intermediates thereof |
WO1998038178A1 (fr) * | 1997-02-26 | 1998-09-03 | Eli Lilly And Company | Composes pharmaceutiques a base de tripeptides et de tetrapeptides |
PL335478A1 (en) * | 1997-02-26 | 2000-04-25 | Lilly Co Eli | Method of obtaining pharmaceutic compounds |
EP0870501A1 (fr) * | 1997-04-11 | 1998-10-14 | Eli Lilly And Company | Utilisation de dérivés spécifiques de la cryptophycine dans la fabrication d'un médicametn destiné au traitement des mycoses |
EP0870506A1 (fr) * | 1997-04-11 | 1998-10-14 | Eli Lilly And Company | Compositions comprenant un dérivé de la cryptophycine associé à un agent de synchronisation ou d'activation pour le traitement du cancer |
US6180679B1 (en) * | 1998-04-07 | 2001-01-30 | Eli Lilly And Company | Method for treating fungal infections |
US6103913A (en) * | 1998-10-16 | 2000-08-15 | Eli Lilly And Company | Process for preparing enollactone derivatives |
US6376230B1 (en) | 1998-10-16 | 2002-04-23 | Eli Lilly And Company | Stereoselective process for producing intermediates of cryptophycins |
AU775373B2 (en) | 1999-10-01 | 2004-07-29 | Immunogen, Inc. | Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents |
AU2002238939A1 (en) * | 2002-03-18 | 2003-09-29 | Nihon University | Cyclic etheramine derivatives as medicaments for malignant tumors |
US7229814B2 (en) * | 2004-05-05 | 2007-06-12 | Regents Of The University Of Minnesota | Nucleic acids and polypeptides involved in the production of cryptophycin |
WO2007000994A1 (fr) * | 2005-06-28 | 2007-01-04 | Chugai Seiyaku Kabushiki Kaisha | Procede de production d’un compose dote d’une action anti-hcv |
CN103724290B (zh) * | 2013-11-15 | 2015-04-29 | 浙江大学 | 一种环肽化合物clavatustide A及其产生菌、制备方法和应用 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4845086A (en) * | 1988-08-09 | 1989-07-04 | Merck & Co., Inc. | Antifungal agent |
WO1996040184A1 (fr) * | 1995-03-07 | 1996-12-19 | University Of Hawaii | Nouvelles cryptophycines obtenues par synthese |
WO1996039829A1 (fr) * | 1995-06-07 | 1996-12-19 | University Of Hawaii | Nouvelles cryptophycines |
WO1997008334A1 (fr) * | 1995-08-30 | 1997-03-06 | University Of Hawaii | Cryptophycines obtenues a partir d'une biosynthese aberrante |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4868208A (en) * | 1988-07-15 | 1989-09-19 | Merck & Co., Inc. | Antifungal agent and method |
US4946835A (en) * | 1988-07-15 | 1990-08-07 | Merck & Co., Inc. | Antifungal fermentation product and method |
US4845085A (en) * | 1988-08-09 | 1989-07-04 | Merck & Co., Inc. | Antifungal agent |
-
1996
- 1996-08-30 WO PCT/US1996/014670 patent/WO1997008334A1/fr not_active Application Discontinuation
- 1996-08-30 WO PCT/US1996/013855 patent/WO1997007798A1/fr not_active Application Discontinuation
- 1996-08-30 EP EP96932217A patent/EP0850316A4/fr not_active Withdrawn
- 1996-08-30 EP EP96929780A patent/EP0850057A4/fr not_active Withdrawn
- 1996-08-30 AU AU71090/96A patent/AU709828B2/en not_active Ceased
- 1996-08-30 AU AU69048/96A patent/AU6904896A/en not_active Abandoned
- 1996-08-30 JP JP9510549A patent/JP2000501067A/ja active Pending
- 1996-08-30 JP JP9510664A patent/JP2000507805A/ja active Pending
- 1996-08-30 CA CA002246117A patent/CA2246117A1/fr not_active Abandoned
- 1996-08-30 BR BR9610214A patent/BR9610214A/pt not_active Application Discontinuation
- 1996-08-30 CA CA002230540A patent/CA2230540A1/fr not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4845086A (en) * | 1988-08-09 | 1989-07-04 | Merck & Co., Inc. | Antifungal agent |
WO1996040184A1 (fr) * | 1995-03-07 | 1996-12-19 | University Of Hawaii | Nouvelles cryptophycines obtenues par synthese |
WO1996039829A1 (fr) * | 1995-06-07 | 1996-12-19 | University Of Hawaii | Nouvelles cryptophycines |
WO1997008334A1 (fr) * | 1995-08-30 | 1997-03-06 | University Of Hawaii | Cryptophycines obtenues a partir d'une biosynthese aberrante |
Non-Patent Citations (4)
Title |
---|
BARROW, RUSSELL A. ET AL: "Total Synthesis of Cryptophycins. Revision of the Structures of Cryptophycins A and C", J. AM. CHEM. SOC. (1995), 117(9), 2479-90, XP002066281 * |
KOBAYASHI, MOTOMASA ET AL: "The absolute stereostructure of arenastatin A, a potent cytotoxic depsipeptide from the Okinawan marine sponge Dysidea arenaria", CHEM. PHARM. BULL. (1994), 42(10), 2196-8, XP002159595 * |
See also references of WO9707798A1 * |
TRIMURTULU, GOLAKOTI ET AL: "Total Structures of Cryptophycins, Potent Antitumor Depsipeptides from th Blue-Green Alga Nostoc sp. Strain GSV 224", J. AM. CHEM. SOC. (1994), 116(11), 4729-37, XP002159594 * |
Also Published As
Publication number | Publication date |
---|---|
CA2230540A1 (fr) | 1997-03-06 |
WO1997007798A1 (fr) | 1997-03-06 |
AU6904896A (en) | 1997-03-19 |
WO1997008334A1 (fr) | 1997-03-06 |
AU7109096A (en) | 1997-03-19 |
EP0850316A4 (fr) | 2000-08-23 |
CA2246117A1 (fr) | 1997-03-06 |
BR9610214A (pt) | 1999-06-15 |
EP0850057A1 (fr) | 1998-07-01 |
EP0850316A1 (fr) | 1998-07-01 |
JP2000501067A (ja) | 2000-02-02 |
AU709828B2 (en) | 1999-09-09 |
JP2000507805A (ja) | 2000-06-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19980226 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI NL PT SE |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20010222 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI NL PT SE |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: WAYNE STATE UNIVERSITY Owner name: UNIVERSITY OF HAWAII |
|
17Q | First examination report despatched |
Effective date: 20030826 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20040106 |