EP0757695A1 - Guamidino-substituierte verbindungen - Google Patents

Guamidino-substituierte verbindungen

Info

Publication number
EP0757695A1
EP0757695A1 EP95916540A EP95916540A EP0757695A1 EP 0757695 A1 EP0757695 A1 EP 0757695A1 EP 95916540 A EP95916540 A EP 95916540A EP 95916540 A EP95916540 A EP 95916540A EP 0757695 A1 EP0757695 A1 EP 0757695A1
Authority
EP
European Patent Office
Prior art keywords
compound
propylguanidine
dideoxy
hexoside
erythro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP95916540A
Other languages
English (en)
French (fr)
Inventor
Sumanas Rakhit
Abdelmalik Slassi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allelix Biopharmaceuticals Inc
Original Assignee
Allelix Biopharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allelix Biopharmaceuticals Inc filed Critical Allelix Biopharmaceuticals Inc
Publication of EP0757695A1 publication Critical patent/EP0757695A1/de
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/16—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/08—Polyoxyalkylene derivatives
EP95916540A 1994-04-28 1995-04-28 Guamidino-substituierte verbindungen Ceased EP0757695A1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23412194A 1994-04-28 1994-04-28
US234121 1994-04-28
PCT/CA1995/000250 WO1995029926A1 (en) 1994-04-28 1995-04-28 Guanidino-substituted compounds

Publications (1)

Publication Number Publication Date
EP0757695A1 true EP0757695A1 (de) 1997-02-12

Family

ID=22880020

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95916540A Ceased EP0757695A1 (de) 1994-04-28 1995-04-28 Guamidino-substituierte verbindungen

Country Status (4)

Country Link
EP (1) EP0757695A1 (de)
AU (1) AU2301295A (de)
CA (1) CA2188452C (de)
WO (1) WO1995029926A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2771092B1 (fr) * 1997-11-18 1999-12-17 Rhone Poulenc Rorer Sa Procede de preparation de derives de la classe des taxoides
US6525182B1 (en) * 2000-01-21 2003-02-25 Regents Of The University Of California Guanidinylation, guanidinoglycosides, uses, and methods of assaying their activity

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2032420A1 (en) * 1989-12-22 1991-06-23 Akira Okuyama Guanidinobenzene derivatives
US5627194A (en) * 1993-11-17 1997-05-06 Allelix Biopharmaceuticals Inc. Anti-viral guanidino-substituted compounds

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO9529926A1 *

Also Published As

Publication number Publication date
CA2188452A1 (en) 1995-11-09
CA2188452C (en) 2000-12-05
WO1995029926A1 (en) 1995-11-09
AU2301295A (en) 1995-11-29

Similar Documents

Publication Publication Date Title
KR100687809B1 (ko) 약제화합물들
WO2009071726A1 (es) Un procedimiento para la preparación de capecitabina e intermediarios utilizables en dicho procedimiento
Unverzagt et al. Stereoselective synthesis of glycosides and anomeric azides of glucosamine
US8399634B2 (en) Reagents and methods for preparing LPS antagonist B1287 and stereoisomers thereof
US6642365B1 (en) Anti-(retro)viral conjugates of saccharides and acetamidino or guanidino compounds
JP3918953B2 (ja) ２個の糖とスペーサーとを含んでなる二結合体
US4187297A (en) 3-De-O-methyl-2-N-acyl and alkyl fortimicins A and B
EP0909763B1 (de) Colchicin-derivate sowie ihre therapeutische Verwendung
CA1128039A (en) Pseudotrissaccharides, a process for their production and their use as medicaments
CA2188452C (en) Guanidino-substituted compounds
FI101796B (fi) Uusia -glukosidaasi-inhibiittoreita
US5627194A (en) Anti-viral guanidino-substituted compounds
JPH0567640B2 (de)
EP0716856A2 (de) Therapeutische Anwendungen von 2',5'-Oligoadenylat-Derivaten
JP2806621B2 (ja) 新規アントラサイクリン類及びその製造方法
EP2077847B1 (de) Sucralose monolaurat und sucralose monomyristat, pharmazeutische formulierungen, diagnosekits und behandlungsverfahren
Aaberg et al. Facile preparation of 1, 6-anhydrohexoses using solvent effects and a catalytic amount of a Lewis acid
US4187298A (en) 2'N-acyl and alkyl fortimicin B and derivatives, 4,2'-N,N'diacyl and dialkyl fortimicin B derivatives 4-N-acyl-2'-N-alkyl and 4-N-alkyl-2'-N-acyl fortimicin B derivatives
HU176891B (en) Process for preparing nitroso-carbamide derivatives
JPH0592987A (ja) ４′−デメチルエピポドフイロトキシングリコシド類
EP2289904A1 (de) Hemmer für mikrobielle Infektionen
US4196197A (en) 2'N-Acyl and alkyl-6'-N-alkyl- and 6',6'-di-N-alkyl derivatives of fortimicins A and B
CA2528223C (en) Colchicoside analogues
Tanahashi et al. Synthetic studies on selectin ligands/inhibitors: a systematic synthesis of sulfatide and its higher congeners carrying 2-(tetradecyl) hexadecyl group as a ceramide substitute
RU2065863C1 (ru) Производные дезацетилколхицина, способ их получения и противоопухолевая композиция

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19961114

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

17Q First examination report despatched

Effective date: 19970127

GRAG Despatch of communication of intention to grant

Free format text: ORIGINAL CODE: EPIDOS AGRA

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED

18R Application refused

Effective date: 19981019