EP0730710B1 - Inhalator mit einrichtung für drehmomentübertragung in einer drehrichtung - Google Patents
Inhalator mit einrichtung für drehmomentübertragung in einer drehrichtung Download PDFInfo
- Publication number
- EP0730710B1 EP0730710B1 EP95903582A EP95903582A EP0730710B1 EP 0730710 B1 EP0730710 B1 EP 0730710B1 EP 95903582 A EP95903582 A EP 95903582A EP 95903582 A EP95903582 A EP 95903582A EP 0730710 B1 EP0730710 B1 EP 0730710B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- shaft
- annular member
- outer annular
- inhaler
- driving
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16D—COUPLINGS FOR TRANSMITTING ROTATION; CLUTCHES; BRAKES
- F16D41/00—Freewheels or freewheel clutches
- F16D41/18—Freewheels or freewheel clutches with non-hinged detent
Definitions
- This invention relates to an inhaler comprising a device for the transmission of one-way torque and in particular to a device which may readily be moulded from plastics and can transmit high driving forces.
- Devices for transmission of one-way torque are well known, common examples include a socket wrench and the winding mechanism of a clockwork motor, watch, clock etc.
- Generally such devices comprise at least one metal part and a biasing spring to bias a pawl in engagement with the teeth of a ratchet wheel.
- W090/13328 discloses a dry powder inhalation device comprising a housing defining a chamber in communication with a patient port in the form of a mouthpiece or nasal adaptor, and an elongate carrier bearing a powdered medicament, the device being constructed and arranged such that areas of predetermined size of the elongate carrier may sequentially be exposed within the chamber, the device comprising one or more air inlets such that when a patient inhales through the patient port an air flow is established from the air inlet(s) to the patient port through the chamber such that particles of the powdered medicament of respirable size from said exposed area of the elongate carrier are entrained within the air flow.
- the elongate carrier is preferably in the form of a tape having a surface with grooves, pores, apertures or other embossed features which contain particles of medicament.
- the tape is conveniently wound on a supply spool and preferably contained within a cassette having a supply and take-up spool.
- the tape may contain many doses of the drug e.g. 200 doses.
- areas of the tape are sequentially advanced into the chamber to dispense the medicament contained within that area of tape. It is essential that the tape is advanced in well defined steps from the supply to the take-up spool to facilitate accurate, reproducible dosing and to prevent drug wastage.
- the advancement of the tape is conveniently facilitated by pivotal movement of a lever, either in a similar manner to the winder lever of a camera, or more preferably in the form of a mouthpiece cover, such that the tape is automatically advanced when the patient opens the cover.
- Such arrangements require an efficient one-way drive providing precisely controlled advancement and so that closure of the cover causes no movement of the tape.
- the requirements of such a drive mechanism for use in an inhaler are manifold. It is desirable that the mechanism be cheap, preferably injection moulded in a minimum number of plastic parts.
- the device should be compact and lightweight, able to transmit large drive forces in relation to the torque needed to reverse the mechanism, capable of achieving low levels of variation in any lost motion, reliable, able to withstand temperatures of -20°C to +70°C for several hours without creeping or stress relaxing when "parked” in any configuration, able to resist wear and tear after prolonged usage (several thousand operations in each direction), reasonably immune to dirt or powder ingress, cheap to assemble, and quiet in operation.
- an inhaler having an elongate carrier bearing powdered medicament and an advancement means for moving the carrier to position an area of the carrier in a predetermined place for dispensing medicament, characterised in that the advancement means comprises a device for the transmission of one-way torque comprising:
- the driving surfaces of the teeth and slider or pawl are preferably substantially radial and the length of the slider or pawl allows engagement of only one of the drive elements at a time.
- Either the shaft or the outer annular member may be connected to a drive means e.g. lever, inhaler cover etc.
- the drive means is connected to the shaft.
- the outer annular member may be axially connected to a spool etc. or may comprise gear teeth moulded onto its radially outer surface which may be used to drive a spool etc. via a gear wheel.
- Figure 1 shows a cross-section through a transmission device for use in the invention comprising an outer annular member (2) having 16 inwardly projecting teeth (4) each comprising a driving surface (6) and a cam surface (8).
- the annular member (2) may be a gear wheel having gear teeth (not shown) projecting radially outwardly.
- a shaft (10) is concentrically mounted within the outer annular member (2) and is associated with two drive elements (12,14) which are joined to form a slider (16).
- Each drive element (12,14) comprises a driving surface (18,20) and a cam surface (22,24).
- the slider (16) is located within channel (26) within the shaft (10) and is free to reciprocate in the radial direction. In order to minimise friction between the slider (16) and the walls of the channel the surface areas in contact are reduced by the presence of rounded projections (28) extending from the wall of the channel (26). It will be appreciated such projections may equally well be present on the slider (16).
- the shaft (10) may be attached to a lever (not shown) e.g. the pivoting cover of an inhaler, to cause rotional movement of the shaft (10).
- a further advantage of the device is the lack of potential creep of such a plastic ratchet mechanism.
- Most known ratchets require springs of some nature for them to operate correctly. The choice is usually either a metal spring, which can be expensive, hard to produce accurately to small tolerances, and may cause substantial wear of other fine plastics parts, or a plastics spring which will suffer from creep or stress relaxation if parked under any significant loading force at elevated temperatures.
- Most simple fine scale plastics ratchet mechanisms are unable to ensure that parking cannot occur with a spring in a loaded configuration and leaving most such mechanisms in a hot car in bright sunshine, a few hours at 50°C, for example, would be sufficient for enough creep to occur to prevent the ratchet functioning properly again.
- the device of Figure 1 has no spring function, however, so is not susceptible to such a creep problem.
- Figure 2 shows the slider (16) provided with two plastic spring wings (30), the ends of which are retained within recesses (32).
- the wings (30) may be formed integrally with the slider (16).
- the wings (30) have a bistable action tending to move the slider (16) towards one of its ends or the other with a snap action.
- Full engagement of a drive element at the end of the slider with a tooth (4) will thus tend to be more assured, reducing the possibility of tip wear of the slider due to large torques being transmitted via too small a tip/tooth overlap.
Landscapes
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Transmission Devices (AREA)
- Retarders (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Lubricants (AREA)
- External Artificial Organs (AREA)
- Basic Packing Technique (AREA)
- Gear Transmission (AREA)
- Power Steering Mechanism (AREA)
Claims (6)
- Inhaliergerät mit einem länglichen Träger, der ein pulverförmiges Medikament aufnimmt, und einem Fortbewegungsmittel zum Bewegen des Trägers, um einen Bereich des Trägers an einem vorbestimmten Ort zur Ausgabe des Medikamentes zu positionieren, dadurch gekennzeichnet, dass das Fortbewegungsmittel eine Vorrichtung zur Übertragung eines Drehmomentes in einer Richtung aufweist, die folgendes umfasst:ein äußeres Ringelement (2) mit einer Mehrzahl von radial nach innen vorstehenden Zähnen (4), wobei jeder Zahn (4) eine Mitnahmefläche (6) und eine Nockenfläche (8) aufweist,eine Welle (10), die konzentrisch in Bezug auf das äußere Ringelement montiert ist, wobei die Welle eine Mehrzahl von Antriebselementen (12, 14) umfasst, die jeweils eine Mitnahmefläche (18, 20) und eine Nockenfläche (22, 24) aufweisen, wobei zwei der genannten Antriebselemente miteinander verbunden sind und einen Schieber (16) bilden, der im wesentlichen diametral über die Welle verläuft, wobei die genannten Antriebselemente so auf der Welle montiert sind, dass eine radiale Bewegung relativ zur Welle möglich ist, sodass:eine Rotation der Welle oder des äußeren Ringelementes in seiner Mitnahmerichtung ein Eingreifen einer Mitnahmefläche (18, 20) von wenigstens einem Antriebselement (12, 14) in eine Mitnahmefläche (6) von wenigstens einem Zahn (4) bewirkt, wodurch sich eine gemeinsame Rotation der Welle und des äußeren Ringelementes ergibt, undeine Rotation der Welle oder des äußeren Ringelementes in der der Mitnahmerichtung entgegengesetzten Richtung einen Eingriff der Nockenfläche (22, 24) von wenigstens einem Antriebselement (12, 14) in die Nockenfläche (8) von wenigstens einem Zahn bewirkt, was eine zusätzliche relative, im wesentlichen radiale, Bewegung zwischen dem genannten Antriebselement und dem genannten Zahn ergibt, wodurch verhindert wird, dass eine Drehbewegung zwischen der genannten Welle und dem genannten äußeren Ringelement übertragen wird,
wobei der genannte Eingriff der Mitnahmeflächen in die Nockenflächen keine Federvorspannmittel erfordert. - Inhaliergerät nach Anspruch 1, bei dem der Schieber in einem Kanal (26) in der Welle gehalten wird.
- Inhaliergerät nach Anspruch 1 oder Anspruch 2, bei dem das äußere Ringelement wenigstens acht feste, radial nach innen vorstehende Zähne umfasst.
- Inhaliergerät nach einem der vorherigen Ansprüche, bei dem der Schieber bis zu seinen äußersten Radialpositionen bistabil ist.
- Inhaliergerät nach einem der vorherigen Ansprüche, bei dem das Fortbewegungsmittel vollkommen aus Kunststoff hergestellt ist.
- Inhaliergerät nach Anspruch 5, bei dem der Kunststoff Polyacetal ist.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB939324391A GB9324391D0 (en) | 1993-11-26 | 1993-11-26 | Device for transmission of one-way torque |
GB9324391 | 1993-11-26 | ||
PCT/US1994/013464 WO1995014867A1 (en) | 1993-11-26 | 1994-11-21 | Device for transmission of one-way torque |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0730710A1 EP0730710A1 (de) | 1996-09-11 |
EP0730710B1 true EP0730710B1 (de) | 2000-09-20 |
Family
ID=10745785
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP95903582A Expired - Lifetime EP0730710B1 (de) | 1993-11-26 | 1994-11-21 | Inhalator mit einrichtung für drehmomentübertragung in einer drehrichtung |
Country Status (14)
Country | Link |
---|---|
US (1) | US6102179A (de) |
EP (1) | EP0730710B1 (de) |
JP (1) | JP3635308B2 (de) |
AT (1) | ATE196534T1 (de) |
AU (1) | AU687959B2 (de) |
CA (1) | CA2177360A1 (de) |
DE (1) | DE69425978T2 (de) |
DK (1) | DK0730710T3 (de) |
ES (1) | ES2152378T3 (de) |
GB (1) | GB9324391D0 (de) |
GR (1) | GR3035086T3 (de) |
PT (1) | PT730710E (de) |
SG (1) | SG49151A1 (de) |
WO (1) | WO1995014867A1 (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10218664A1 (de) * | 2002-04-26 | 2003-11-13 | Sram De Gmbh | Freilaufnabe |
GB0317374D0 (en) * | 2003-07-24 | 2003-08-27 | Glaxo Group Ltd | Medicament dispenser |
GB0418278D0 (en) * | 2004-08-16 | 2004-09-15 | Glaxo Group Ltd | Medicament dispenser |
GB0515584D0 (en) * | 2005-07-28 | 2005-09-07 | Glaxo Group Ltd | Medicament dispenser |
US8517019B2 (en) * | 2006-03-03 | 2013-08-27 | 3M Innovative Properties Company | Method and apparatus for metered dose dispensing |
GB0605150D0 (en) | 2006-03-14 | 2006-04-26 | Glaxo Group Ltd | Counter For Use With A Medicament Dispenser |
GB0605723D0 (en) | 2006-03-23 | 2006-05-03 | 3M Innovative Properties Co | Powder filling processes |
GB0622827D0 (en) * | 2006-11-15 | 2006-12-27 | Glaxo Group Ltd | Sheet driver for use in a drug dispenser |
EP2534958A1 (de) | 2007-12-14 | 2012-12-19 | AeroDesigns, Inc | Abgabe von Aerosol-sprühbaren Nahrungsmittelprodukten |
WO2010135253A2 (en) * | 2009-05-18 | 2010-11-25 | 3M Innovative Properties Company | Dry powder inhaler dose counters |
US20100301609A1 (en) * | 2009-05-30 | 2010-12-02 | Chong Hun Kim | River-Flow Electricity Generation |
EP2874928B1 (de) | 2012-07-19 | 2016-06-15 | Adamis Pharmaceuticals Corporation | Pulverzufuhrvorrichtung |
CN105324586B (zh) * | 2013-05-22 | 2018-12-07 | 舍弗勒技术股份两合公司 | 空程装置 |
DE102013219880B4 (de) * | 2013-10-01 | 2015-09-10 | Schaeffler Technologies AG & Co. KG | Freilauf, der einfach aufgebaut, kostengünstig herstellbar und montierbar ist |
DE102013227008B4 (de) | 2013-12-20 | 2021-08-12 | Seg Automotive Germany Gmbh | Andrehvorrichtung und Verfahren hierzu |
GB201702473D0 (en) * | 2017-02-15 | 2017-03-29 | Univ Newcastle | Gear |
JP6920728B2 (ja) * | 2017-09-14 | 2021-08-18 | 下西技研工業株式会社 | ワンウェイクラッチおよびワンウェイクラッチ付き回転ダンパ装置 |
JP7219948B2 (ja) * | 2018-06-11 | 2023-02-09 | 下西技研工業株式会社 | ワンウェイクラッチおよびワンウェイクラッチ付き回転ダンパ装置 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US203519A (en) * | 1878-05-07 | Improvement in pawl-and-ratchet devices | ||
GB314892A (en) * | 1928-07-04 | 1929-10-24 | Paul Duluc | An improved free-wheel mechanism |
BE354444A (de) * | 1928-09-24 | 1928-10-31 | ||
GB346548A (en) * | 1930-03-19 | 1931-04-16 | Jonas Arthur Knight | Improvements in power transmission mechanism |
GB556080A (en) * | 1941-02-12 | 1943-09-20 | Clemson Bros Inc | Improved free-wheel or ratchet clutch mechanism |
US2905294A (en) * | 1956-03-12 | 1959-09-22 | Clemson Bros Inc | Shuttle-pin clutch drive mechanism for lawn mowers |
GB908128A (en) * | 1958-06-10 | 1962-10-17 | Andre Duban | Improvements in or relating to ratchet-and-pawl devices |
US3300003A (en) * | 1964-11-25 | 1967-01-24 | Eastman Kodak Co | Unidirectional clutch mechanism |
US4570769A (en) * | 1981-11-26 | 1986-02-18 | Kabushiki Kaisha Sankyo Seiki Seisakusho | Ratchet mechanism |
DE3440264A1 (de) * | 1984-11-03 | 1986-05-15 | Rudolf Wittner Gmbh U. Co, 7972 Isny | Aufziehbares uhrwerk fuer metronom |
US5000721A (en) * | 1987-08-20 | 1991-03-19 | Itt Corporation | Clutch apparatus |
EP0705614B1 (de) * | 1989-04-28 | 2002-09-25 | Riker Laboratories, Inc. | Inhalationsvorrichtung für Trockenpulver |
GB8909891D0 (en) * | 1989-04-28 | 1989-06-14 | Riker Laboratories Inc | Device |
-
1993
- 1993-11-26 GB GB939324391A patent/GB9324391D0/en active Pending
-
1994
- 1994-11-21 CA CA002177360A patent/CA2177360A1/en not_active Abandoned
- 1994-11-21 DK DK95903582T patent/DK0730710T3/da active
- 1994-11-21 WO PCT/US1994/013464 patent/WO1995014867A1/en active IP Right Grant
- 1994-11-21 ES ES95903582T patent/ES2152378T3/es not_active Expired - Lifetime
- 1994-11-21 DE DE69425978T patent/DE69425978T2/de not_active Expired - Lifetime
- 1994-11-21 AU AU12586/95A patent/AU687959B2/en not_active Ceased
- 1994-11-21 PT PT95903582T patent/PT730710E/pt unknown
- 1994-11-21 JP JP51518195A patent/JP3635308B2/ja not_active Expired - Fee Related
- 1994-11-21 SG SG1996006882A patent/SG49151A1/en unknown
- 1994-11-21 AT AT95903582T patent/ATE196534T1/de not_active IP Right Cessation
- 1994-11-21 EP EP95903582A patent/EP0730710B1/de not_active Expired - Lifetime
-
1997
- 1997-05-05 US US08/850,439 patent/US6102179A/en not_active Expired - Lifetime
-
2000
- 2000-12-15 GR GR20000402774T patent/GR3035086T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JP3635308B2 (ja) | 2005-04-06 |
SG49151A1 (en) | 1998-05-18 |
AU1258695A (en) | 1995-06-13 |
PT730710E (pt) | 2001-03-30 |
US6102179A (en) | 2000-08-15 |
GB9324391D0 (en) | 1994-01-12 |
ES2152378T3 (es) | 2001-02-01 |
JPH10501869A (ja) | 1998-02-17 |
CA2177360A1 (en) | 1995-06-01 |
AU687959B2 (en) | 1998-03-05 |
DE69425978D1 (de) | 2000-10-26 |
GR3035086T3 (en) | 2001-03-30 |
WO1995014867A1 (en) | 1995-06-01 |
EP0730710A1 (de) | 1996-09-11 |
ATE196534T1 (de) | 2000-10-15 |
DK0730710T3 (da) | 2001-01-29 |
DE69425978T2 (de) | 2001-05-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP0730710B1 (de) | Inhalator mit einrichtung für drehmomentübertragung in einer drehrichtung | |
US7823824B2 (en) | Device for winding a safety belt | |
US5009338A (en) | Indicator cap for a medicine bottle | |
AU639877B2 (en) | One-way clutch | |
US6554800B1 (en) | Compact pump motor system and dispensing process | |
CA2100771C (en) | Indicator cap | |
CA2605937A1 (en) | Drive unit for medical devices | |
CZ18311U1 (cs) | Pocítadlo inhalátoru | |
US6189666B1 (en) | Ratchet mechanism | |
CN113904498B (zh) | 一种回转执行器 | |
US6286649B1 (en) | Unidirectional rotary drive mechanism for multi-part construction toy | |
US6488122B2 (en) | Apparatus for generating rotative force using spring | |
JP4007278B2 (ja) | 流体吐出装置 | |
US2528148A (en) | Overrunning clutch and pinion unit | |
JP2006153174A (ja) | 直線駆動装置 | |
JPH03189485A (ja) | 電動アクチユエータ | |
KR940000646B1 (ko) | 소형 데크 메커니즘의 릴 제동용 일방향 클러치장치 | |
KR940002963Y1 (ko) | 원웨이 클러치 장치 | |
JPS5929149Y2 (ja) | スプリングクラツチ用駆動軸 | |
JPS58214055A (ja) | 回転動力伝達装置 | |
JPS632904Y2 (de) | ||
JPH084945Y2 (ja) | サイクルミシンにおける送りカムのオーバーラン防止装置 | |
JPH07119753A (ja) | ヘリコイドクラッチ | |
JPH0253594B2 (de) | ||
SU434366A1 (ru) | Пружинный двигатель часов |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19960613 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE |
|
17Q | First examination report despatched |
Effective date: 19990701 |
|
GRAG | Despatch of communication of intention to grant |
Free format text: ORIGINAL CODE: EPIDOS AGRA |
|
RIC1 | Information provided on ipc code assigned before grant |
Free format text: 7F 16D 41/18 A |
|
RTI1 | Title (correction) |
Free format text: INHALER COMPRISING A DEVICE FOR TRANSMISSION OF ONE-WAY TORQUE |
|
17Q | First examination report despatched |
Effective date: 19990701 |
|
GRAG | Despatch of communication of intention to grant |
Free format text: ORIGINAL CODE: EPIDOS AGRA |
|
GRAH | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOS IGRA |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: ASTRAZENECA AB |
|
GRAH | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOS IGRA |
|
GRAA | (expected) grant |
Free format text: ORIGINAL CODE: 0009210 |
|
AK | Designated contracting states |
Kind code of ref document: B1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE |
|
REF | Corresponds to: |
Ref document number: 196534 Country of ref document: AT Date of ref document: 20001015 Kind code of ref document: T |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: EP |
|
REF | Corresponds to: |
Ref document number: 69425978 Country of ref document: DE Date of ref document: 20001026 |
|
REG | Reference to a national code |
Ref country code: IE Ref legal event code: FG4D |
|
ITF | It: translation for a ep patent filed |
Owner name: MODIANO & ASSOCIATI S.R.L. |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: NV Representative=s name: E. BLUM & CO. PATENTANWAELTE |
|
ET | Fr: translation filed | ||
REG | Reference to a national code |
Ref country code: DK Ref legal event code: T3 |
|
REG | Reference to a national code |
Ref country code: ES Ref legal event code: FG2A Ref document number: 2152378 Country of ref document: ES Kind code of ref document: T3 |
|
REG | Reference to a national code |
Ref country code: PT Ref legal event code: SC4A Free format text: AVAILABILITY OF NATIONAL TRANSLATION Effective date: 20001215 |
|
PLBE | No opposition filed within time limit |
Free format text: ORIGINAL CODE: 0009261 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT |
|
26N | No opposition filed | ||
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: SE Payment date: 20011101 Year of fee payment: 8 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: NL Payment date: 20011102 Year of fee payment: 8 Ref country code: DK Payment date: 20011102 Year of fee payment: 8 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: CH Payment date: 20011105 Year of fee payment: 8 Ref country code: AT Payment date: 20011105 Year of fee payment: 8 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: MC Payment date: 20011107 Year of fee payment: 8 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: LU Payment date: 20011115 Year of fee payment: 8 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: GR Payment date: 20011121 Year of fee payment: 8 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: PT Payment date: 20011123 Year of fee payment: 8 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: IE Payment date: 20011130 Year of fee payment: 8 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: BE Payment date: 20011218 Year of fee payment: 8 |
|
REG | Reference to a national code |
Ref country code: GB Ref legal event code: IF02 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LU Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20021121 Ref country code: IE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20021121 Ref country code: AT Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20021121 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20021122 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LI Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20021130 Ref country code: CH Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20021130 Ref country code: BE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20021130 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: DK Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20021231 |
|
REG | Reference to a national code |
Ref country code: GB Ref legal event code: 732E |
|
BERE | Be: lapsed |
Owner name: *ASTRAZENECA A.B. Effective date: 20021130 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: PT Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20030531 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: NL Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20030601 Ref country code: MC Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20030601 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: GR Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20030609 |
|
EUG | Se: european patent has lapsed | ||
REG | Reference to a national code |
Ref country code: DK Ref legal event code: EBP |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: PL |
|
NLV4 | Nl: lapsed or anulled due to non-payment of the annual fee |
Effective date: 20030601 |
|
REG | Reference to a national code |
Ref country code: PT Ref legal event code: MM4A Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20030531 |
|
REG | Reference to a national code |
Ref country code: IE Ref legal event code: MM4A |
|
REG | Reference to a national code |
Ref country code: FR Ref legal event code: TP |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: ES Payment date: 20071126 Year of fee payment: 14 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: IT Payment date: 20071128 Year of fee payment: 14 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IT Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20081121 |
|
REG | Reference to a national code |
Ref country code: ES Ref legal event code: FD2A Effective date: 20081122 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: ES Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20081122 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: DE Payment date: 20131113 Year of fee payment: 20 Ref country code: GB Payment date: 20131120 Year of fee payment: 20 Ref country code: FR Payment date: 20131108 Year of fee payment: 20 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R071 Ref document number: 69425978 Country of ref document: DE |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R071 Ref document number: 69425978 Country of ref document: DE |
|
REG | Reference to a national code |
Ref country code: GB Ref legal event code: PE20 Expiry date: 20141120 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: GB Free format text: LAPSE BECAUSE OF EXPIRATION OF PROTECTION Effective date: 20141120 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R082 Ref document number: 69425978 Country of ref document: DE Representative=s name: PATENTANWAELTE LIPPERT, STACHOW & PARTNER, DE |