EP0727490A4 - Prostacyclinsynthase aus mensch - Google Patents

Prostacyclinsynthase aus mensch

Info

Publication number
EP0727490A4
EP0727490A4 EP95917481A EP95917481A EP0727490A4 EP 0727490 A4 EP0727490 A4 EP 0727490A4 EP 95917481 A EP95917481 A EP 95917481A EP 95917481 A EP95917481 A EP 95917481A EP 0727490 A4 EP0727490 A4 EP 0727490A4
Authority
EP
European Patent Office
Prior art keywords
pgis
human
dna
originated
vector
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP95917481A
Other languages
English (en)
French (fr)
Other versions
EP0727490A1 (de
EP0727490B1 (de
Inventor
Tadashi Tanabe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP0727490A1 publication Critical patent/EP0727490A1/de
Publication of EP0727490A4 publication Critical patent/EP0727490A4/de
Application granted granted Critical
Publication of EP0727490B1 publication Critical patent/EP0727490B1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Curing Cements, Concrete, And Artificial Stone (AREA)
  • Silicon Polymers (AREA)
EP95917481A 1994-04-28 1995-04-27 Humane prostacyclinsynthase Expired - Lifetime EP0727490B1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP114316/94 1994-04-28
JP11431694 1994-04-28
PCT/JP1995/000838 WO1995030013A1 (en) 1994-04-28 1995-04-27 Human-origin prostacyclin synthase

Publications (3)

Publication Number Publication Date
EP0727490A1 EP0727490A1 (de) 1996-08-21
EP0727490A4 true EP0727490A4 (de) 2002-05-29
EP0727490B1 EP0727490B1 (de) 2006-06-28

Family

ID=14634811

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95917481A Expired - Lifetime EP0727490B1 (de) 1994-04-28 1995-04-27 Humane prostacyclinsynthase

Country Status (6)

Country Link
US (2) US5814509A (de)
EP (1) EP0727490B1 (de)
AT (1) ATE331794T1 (de)
CA (1) CA2166328C (de)
DE (1) DE69535091T2 (de)
WO (1) WO1995030013A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030118567A1 (en) * 1999-03-26 2003-06-26 Stewart Duncan John Cell-based therapy for the pulmonary system
AU6893100A (en) * 1999-08-02 2001-02-19 Avigen, Inc. Use of recombinant adeno-associated virus vector (raav) for the prevention of smooth muscle cell proliferation in vascular graft
JP4632481B2 (ja) * 2000-05-22 2011-02-16 忠 田邉 プロスタサイクリン合成酵素遺伝子含有医薬組成物
CN1274365C (zh) * 2000-06-27 2006-09-13 安增子摩祺株式会社 用于血管形成治疗的药物组合物
US7622260B2 (en) 2001-09-05 2009-11-24 The Brigham And Women's Hospital, Inc. Diagnostic and prognostic tests
JP2005120069A (ja) * 2003-10-13 2005-05-12 Anges Mg Inc 炎症性疾患治療薬
US20120156170A1 (en) 2009-08-31 2012-06-21 Tadashi Tanabe Drug composition for angiogenesis therapy

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
GRYGLEWSKI RJ ET AL: "Prostacyclin and vascular disease", PHILOS TRANS R SOC LOND B BIOL SCI, vol. 294, no. 1072, 18 August 1981 (1981-08-18), pages 383 - 388, XP001062949 *
PEREIRA B ET AL: "BOVINE PROSTACYCLIN SYNTHASE: PURIFICATION AND ISOLATION OF PARTIAL CDNA", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 197, no. 3, 30 December 1993 (1993-12-30), pages 1041 - 1048, XP000570379, ISSN: 0006-291X *
SATOH K ET AL: "Role of prostaglandins in pregnancy-induced hypertension", AM J KIDNEY, vol. 17, no. 2, February 1991 (1991-02-01), pages 133 - 138, XP001062950 *

Also Published As

Publication number Publication date
ATE331794T1 (de) 2006-07-15
EP0727490A1 (de) 1996-08-21
DE69535091D1 (en) 2006-08-10
WO1995030013A1 (en) 1995-11-09
DE69535091T2 (de) 2007-01-04
US5814509A (en) 1998-09-29
US20040049015A1 (en) 2004-03-11
EP0727490B1 (de) 2006-06-28
CA2166328C (en) 2007-08-14
CA2166328A1 (en) 1995-11-09

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