AU2002211446A1 - 32144, a human fatty acid amide hydrolase and uses thereof - Google Patents

32144, a human fatty acid amide hydrolase and uses thereof

Info

Publication number
AU2002211446A1
AU2002211446A1 AU2002211446A AU1144602A AU2002211446A1 AU 2002211446 A1 AU2002211446 A1 AU 2002211446A1 AU 2002211446 A AU2002211446 A AU 2002211446A AU 1144602 A AU1144602 A AU 1144602A AU 2002211446 A1 AU2002211446 A1 AU 2002211446A1
Authority
AU
Australia
Prior art keywords
nucleic acid
fatty acid
acid amide
acid molecules
amide hydrolase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002211446A
Inventor
Rory A. J. Curtis
Kyle J. Macbeth
Laura A. Rudolph-Owen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Millennium Pharmaceuticals Inc
Original Assignee
Millennium Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharmaceuticals Inc filed Critical Millennium Pharmaceuticals Inc
Publication of AU2002211446A1 publication Critical patent/AU2002211446A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Abstract

The invention provides isolated nucleic acids molecules, designated 32144 nucleic acid molecules, which encode novel fatty acid amide hydrolase members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 32144 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 32144 gene has been introduced or disrupted. The invention still further provides isolated 32144 proteins, fusion proteins, antigenic peptides and anti-32144 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
AU2002211446A 2000-10-05 2001-09-27 32144, a human fatty acid amide hydrolase and uses thereof Abandoned AU2002211446A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23805400P 2000-10-05 2000-10-05
US60/238,054 2000-10-05
PCT/US2001/031188 WO2002029057A2 (en) 2000-10-05 2001-09-27 32144, a human fatty acid amide hydrolase and uses thereof

Publications (1)

Publication Number Publication Date
AU2002211446A1 true AU2002211446A1 (en) 2002-04-15

Family

ID=22896307

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002211446A Abandoned AU2002211446A1 (en) 2000-10-05 2001-09-27 32144, a human fatty acid amide hydrolase and uses thereof

Country Status (7)

Country Link
US (1) US20020164769A1 (en)
EP (1) EP1332214B1 (en)
AT (1) ATE449173T1 (en)
AU (1) AU2002211446A1 (en)
DE (1) DE60140559D1 (en)
ES (1) ES2335478T3 (en)
WO (1) WO2002029057A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO3598B1 (en) 2006-10-10 2020-07-05 Infinity Discovery Inc Boronic acids and esters as inhibitors of fatty acid amide hydrolase
TW201000107A (en) * 2008-04-09 2010-01-01 Infinity Pharmaceuticals Inc Inhibitors of fatty acid amide hydrolase
US8207226B1 (en) * 2008-06-03 2012-06-26 Alcon Research, Ltd. Use of FAAH antagonists for treating dry eye and ocular pain
AU2010234445A1 (en) 2009-04-07 2011-11-03 Infinity Pharmaceuticals, Inc. Inhibitors of fatty acid amide hydrolase
WO2010118159A1 (en) 2009-04-07 2010-10-14 Infinity Pharmaceuticals, Inc. Inhibitors of fatty acid amide hydrolase
US9062116B2 (en) 2009-04-23 2015-06-23 Infinity Pharmaceuticals, Inc. Anti-fatty acid amide hydrolase-2 antibodies and uses thereof
US8927551B2 (en) * 2009-05-18 2015-01-06 Infinity Pharmaceuticals, Inc. Isoxazolines as inhibitors of fatty acid amide hydrolase
US9149465B2 (en) * 2009-05-18 2015-10-06 Infinity Pharmaceuticals, Inc. Isoxazolines as inhibitors of fatty acid amide hydrolase
US8765735B2 (en) * 2009-05-18 2014-07-01 Infinity Pharmaceuticals, Inc. Isoxazolines as inhibitors of fatty acid amide hydrolase
RU2569061C2 (en) 2010-02-03 2015-11-20 Инфинити Фармасьютикалз, Инк. Inhibitors of amide-hydrolase of fatty acids
ES2893100T3 (en) 2015-10-12 2022-02-08 Advanced Cell Diagnostics Inc In situ detection of nucleotide variants in samples with a high level of noise, and related compositions and methods

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6069300A (en) * 1999-07-02 2001-01-22 Chiron Corporation Novel human genes and gene expression products
WO2001051628A2 (en) * 2000-01-14 2001-07-19 Millennium Pharmaceuticals, Inc. Genes compositions, kits, and methods for identification, assessment, prevention, and therapy of breast cancer
CA2407435A1 (en) * 2000-04-28 2001-11-08 Incyte Genomics, Inc. Rna metabolism proteins

Also Published As

Publication number Publication date
ES2335478T3 (en) 2010-03-29
EP1332214B1 (en) 2009-11-18
WO2002029057A3 (en) 2003-01-23
ATE449173T1 (en) 2009-12-15
WO2002029057A2 (en) 2002-04-11
DE60140559D1 (en) 2009-12-31
US20020164769A1 (en) 2002-11-07
EP1332214A2 (en) 2003-08-06

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