EP0711135B2 - Stent - Google Patents

Stent Download PDF

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Publication number
EP0711135B2
EP0711135B2 EP95922468A EP95922468A EP0711135B2 EP 0711135 B2 EP0711135 B2 EP 0711135B2 EP 95922468 A EP95922468 A EP 95922468A EP 95922468 A EP95922468 A EP 95922468A EP 0711135 B2 EP0711135 B2 EP 0711135B2
Authority
EP
European Patent Office
Prior art keywords
stent
ribs
stent according
area
vessel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP95922468A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP0711135B1 (de
EP0711135A1 (de
Inventor
Josef Lindenberg
Wolfram Schnepp-Presch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Angiomed GmbH and Co Medizentechnik KG
Original Assignee
Angiomed GmbH and Co Medizentechnik KG
Angiomed AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6518991&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP0711135(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Angiomed GmbH and Co Medizentechnik KG, Angiomed AG filed Critical Angiomed GmbH and Co Medizentechnik KG
Publication of EP0711135A1 publication Critical patent/EP0711135A1/de
Publication of EP0711135B1 publication Critical patent/EP0711135B1/de
Application granted granted Critical
Publication of EP0711135B2 publication Critical patent/EP0711135B2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/91533—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other characterised by the phase between adjacent bands
    • A61F2002/91541—Adjacent bands are arranged out of phase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/9155—Adjacent bands being connected to each other
    • A61F2002/91558—Adjacent bands being connected to each other connected peak to peak
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0028—Shapes in the form of latin or greek characters
    • A61F2230/0054—V-shaped

Definitions

  • the invention relates to a stent for expanding and holding open vessels, with a radially contracted state for introduction into the vessel and with a radially expanded state after insertion into the vessel, the one-piece stent having ribs and between these free spaces.
  • Such stents or implantable catheters insertable into a body cavity, vessel or the like may be made of plastic or inert metal such as steel or nickel-titanium alloys. Such stents are also referred to in particular as endovascular or endoluminal stents or endoprostheses.
  • the stents are used, for example, to dilate the ureter in the prostate area in benign prostatic hyperplasia (BPH) or in calcified blood vessels to expand and keep open the same stents have material areas and spaces between them. This allows the stent to grow around the wall tissue of the open-held organ.
  • Stents may be formed spirally or in the form of a helically wound coil; they may be woven or knitted wire or plastic material.
  • Such stents may have memory or memory properties, as given for example in certain nickel-titanium alloys (Nitinol).
  • a generic stent is known from WO 94/17754 A1.
  • No. 5,064,435 shows a two-part or multi-part.1 stent for expanding and holding vessels with a radially contracted state for introduction into the vessel and with a radially expanded state after introduction into the vessel.
  • the stent consists of at least two stent parts, each of which has a radial expansion at one end.
  • the stent parts are pushed together with their unexpanded end and form an overlap.
  • This two-part training is to be regarded as disadvantageous in production engineering, but also in medical terms, because the Gewebewachs in the overlap is different than in the area outside the same.
  • Another disadvantage is that the radial forces in the area of the expansion by the equally formed lozenges or spaces are fixed.
  • the invention has for its object to enable a secure anchoring of such a stent in the vessel to be dilated.
  • the length of the ribs in the face region is 120-190% of the length of the ribs in the main region of the stent.
  • ribs in the end-face regions extend radially further outward than the ribs in the main region of the stent and that the ribs in the end-face region form a finite angle to the main axis of the stent.
  • the free spaces can be either rhomboid or honeycomb-shaped.
  • the stent is preferably self-expanding and in a preferred embodiment not only due to elastic properties and insertion in a state under radial tension, but in that it consists of shape memory alloy (memory metal).
  • a further preferred embodiment provides that intermediate spaces, partly connecting areas, are provided between ribs arranged one behind the other in the axial direction.
  • intermediate spaces, partly connecting areas are provided between ribs arranged one behind the other in the axial direction.
  • the stent is formed in one layer, a high bending ability is achieved without metal intersection points, as is the case with knitted fabrics, braids, are given, which lead to a greater material thickness. There may be a better ingrowth of the stent according to the invention into the tissue. Furthermore, the risk of the occurrence of thromboses, especially in the vascular area, significantly reduced or practically excluded.
  • connection areas are offset from each other in the circumferential direction.
  • the stent 1 according to the invention has a cylindrical shape or outer contour in its radially contracted state for insertion into the vessel to be dilated, as shown in FIG.
  • the stent 1 according to the invention has the length L of its main body, i. its largest length, also a cylindrical outer contour;
  • the stent according to the invention is in the region of its two end faces 1 b, 1 c on the radial dimensions, i. the diameter D of the main body 1a, radially expanded, so that the stent 1 can anchor with its radially expanded ends 1b, 1c on the vessel wall.
  • the stent 1 consists of a series of meandering tracks A arranged one behind the other in the axial direction A, extending over the circumference of the stent 1 in the form of connecting or tip regions 3, 3a, 3'a, 3b angularly interconnected ribs 2 and 2a and 2b.
  • the meandering tracks or ribs 2, 2a, 2b are arranged such that in each case facing, adjacent connecting or tip portions 3, 3a and 3'a, 3b of respectively juxtaposed meandering tracks or ribs 2, 2a, 2b are aligned in the axial direction ,
  • the meandering tracks which follow one another in the axial direction and which each form the ribs 2, 2a, 2b in the region of their tip or connecting regions 3, 3a, 3'a, 3b are not interrupted by transitions 4, 4a, 4b , 4c. 4d are connected to each other, but that in the circumferential direction between such transitions 4-4d two adjacent, formed by the ribs 2, 2a meandering paths each have a plurality of gaps 5,5 ', 5a. 5b, 5b ', etc. are arranged.
  • the transitional regions 4-4d and gaps 5-5b ' are collectively referred to as nodal regions.
  • the stent according to the invention can be understood to be formed by ribs 2, 2a, 2b and free spaces 6, 6a formed between them, the free spaces 6, 6a in the illustrated embodiment basically being in the shape of a rhombus, i. are limited by four rib areas, in principle, may also have the shape of a honeycomb, wherein they are limited by six rib areas.
  • the nodal regions are partially left as compounds 4-4d, while in other regions they are cut through the gaps 5-5b '.
  • the connections or transitions 4-4d are not aligned in the axial direction, but are each angularly offset from each other or in the circumferential direction.
  • the stent 1 at bending perpendicular to its longitudinal axis A and thus bending of the longitudinal axis itself does not buckle in the central region such that it loses its cross-section substantially circular contour and flattened in the direction of action of the forces in the middle and perpendicular to the
  • the direction of action of the forces is widened approximately in the middle of its longitudinal extent, as is the case with conventional stents, in which all mutually facing, adjacent tip or connecting regions 3, 3a etc. in the axial direction of adjacent meandering turns by connecting areas or transitions 4, 4a fixed are connected.
  • the connecting regions or transitions 4, 4a ... are formed in one piece with the other parts of the stent, in particular the ribs 2, 2a... And their respective adjacent tip or connecting regions 3, 3a.
  • the length of the ribs 2 of the outer or frontal meandering regions is significantly greater than the ribs 2a, 2b in the main body 1a of the stent 1 according to the invention.
  • the length of the end ribs 2 can be between 120 and 200% of the ribs 2a to 2c of the main body 1a.
  • the aspect ratio is largely arbitrary; It is determined by the allowable strain, the required stent length and the desired radial expansion of the end portions 1b, 1c over the main body 1a of the stent 1 out.
  • the stent 1 according to the invention consists of a nickel-titanium alloy, such as Nitinol. It is produced in such a way that sheet metal is first etched with high accuracy, namely with a tolerance range of 0.001 mm, to the desired sheet thickness. Subsequently, the stent forming parts are cut out of large sheet metal. In these sheet metal parts, the openings or slots are then cut in such a way that circumferentially adjacent slots are each offset by half in their length in the axial direction. The cutting of the slots is done by means of a laser. In the middle area of each slot is this one with an extension provided so that the enlargement in the circumferential direction limiting material is reduced approximately to the width of the remaining between the slots itself material stock.
  • the bridges are then removed in the desired manner, so that the connecting areas or webs 4, 4a or the free spaces 5, 5 ', 5a, etc. are formed, as described above.
  • the following is then still a grinding and polishing, preferably in a rotary drum machine.
  • the stents are based on measurements. Function and setting checked. Finally, cleaning takes place in an ultrasonic bath, first with soap solution, then with distilled water and finally with alcohol.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Physics & Mathematics (AREA)
  • Vascular Medicine (AREA)
  • Optics & Photonics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Prostheses (AREA)
EP95922468A 1994-05-26 1995-05-20 Stent Expired - Lifetime EP0711135B2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4418336A DE4418336A1 (de) 1994-05-26 1994-05-26 Stent
DE4418336 1994-05-26
PCT/EP1995/001925 WO1995032688A1 (de) 1994-05-26 1995-05-20 Stent

Publications (3)

Publication Number Publication Date
EP0711135A1 EP0711135A1 (de) 1996-05-15
EP0711135B1 EP0711135B1 (de) 1999-12-01
EP0711135B2 true EP0711135B2 (de) 2007-07-04

Family

ID=6518991

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95922468A Expired - Lifetime EP0711135B2 (de) 1994-05-26 1995-05-20 Stent

Country Status (8)

Country Link
US (2) US5716393A (es)
EP (1) EP0711135B2 (es)
JP (1) JPH09501089A (es)
AT (1) ATE187054T1 (es)
CA (1) CA2168121C (es)
DE (2) DE4418336A1 (es)
ES (1) ES2141946T5 (es)
WO (1) WO1995032688A1 (es)

Families Citing this family (375)

* Cited by examiner, † Cited by third party
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DE4418336A1 (de) 1995-11-30
ATE187054T1 (de) 1999-12-15
EP0711135B1 (de) 1999-12-01
WO1995032688A1 (de) 1995-12-07
ES2141946T5 (es) 2008-02-01
US6053941A (en) 2000-04-25
ES2141946T3 (es) 2000-04-01
CA2168121A1 (en) 1995-12-07
CA2168121C (en) 2006-02-21
DE59507326D1 (en) 2000-01-05
US5716393A (en) 1998-02-10
EP0711135A1 (de) 1996-05-15
JPH09501089A (ja) 1997-02-04

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