EP0671937A4 - Compositions pour emulsions pharmaceutiques. - Google Patents

Compositions pour emulsions pharmaceutiques.

Info

Publication number
EP0671937A4
EP0671937A4 EP93923918A EP93923918A EP0671937A4 EP 0671937 A4 EP0671937 A4 EP 0671937A4 EP 93923918 A EP93923918 A EP 93923918A EP 93923918 A EP93923918 A EP 93923918A EP 0671937 A4 EP0671937 A4 EP 0671937A4
Authority
EP
European Patent Office
Prior art keywords
emulsion compositions
pharmaceutical emulsion
pharmaceutical
compositions
emulsion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP93923918A
Other languages
German (de)
English (en)
Other versions
EP0671937A1 (fr
Inventor
Panayiotis Peri Constantinides
Seang Huoth Yiv
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Affinity Biotech Inc
SmithKline Beecham Corp
Original Assignee
Affinity Biotech Inc
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Affinity Biotech Inc, SmithKline Beecham Corp filed Critical Affinity Biotech Inc
Publication of EP0671937A1 publication Critical patent/EP0671937A1/fr
Publication of EP0671937A4 publication Critical patent/EP0671937A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/25—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
EP93923918A 1992-10-16 1993-10-15 Compositions pour emulsions pharmaceutiques. Withdrawn EP0671937A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US96295592A 1992-10-16 1992-10-16
US962955 1992-10-16
PCT/US1993/009916 WO1994008610A1 (fr) 1992-10-16 1993-10-15 Compositions pour emulsions pharmaceutiques

Publications (2)

Publication Number Publication Date
EP0671937A1 EP0671937A1 (fr) 1995-09-20
EP0671937A4 true EP0671937A4 (fr) 1996-09-18

Family

ID=25506549

Family Applications (1)

Application Number Title Priority Date Filing Date
EP93923918A Withdrawn EP0671937A4 (fr) 1992-10-16 1993-10-15 Compositions pour emulsions pharmaceutiques.

Country Status (3)

Country Link
EP (1) EP0671937A4 (fr)
JP (1) JPH08505367A (fr)
WO (1) WO1994008610A1 (fr)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE921212A1 (en) * 1991-04-19 1992-10-21 Affinity Biotech Inc Convertible microemulsion formulations
US5688761A (en) * 1991-04-19 1997-11-18 Lds Technologies, Inc. Convertible microemulsion formulations
TW438603B (en) * 1993-04-19 2001-06-07 Advanced Skin Res Kenkyusho Kk Microemulsion preparation containing peptide pharmaceuticals
WO1995025504A1 (fr) * 1994-03-18 1995-09-28 Pharmavene, Inc. Systemes d'administration de medicaments emulsionnes
CA2369594A1 (fr) * 1999-05-07 2000-11-16 Pharmasol Gmbh Particules lipidiques a base de melanges de lipides liquides et solides et procede pour les produire
US6790435B1 (en) 1999-10-01 2004-09-14 Unilever Home & Personal Care Usa Division Of Conopco, Inc. Antiperspirant compositions comprising microemulsions
IT1318539B1 (it) * 2000-05-26 2003-08-27 Italfarmaco Spa Composizioni farmaceutiche a rilascio prolungato per lasomministrazione parenterale di sostanze idrofile biologicamente
US6623765B1 (en) 2000-08-01 2003-09-23 University Of Florida, Research Foundation, Incorporated Microemulsion and micelle systems for solubilizing drugs
EP1414497A4 (fr) * 2001-08-08 2007-11-21 Univ Florida Nouveaux systemes de micelles et de micro-emulsions pour la solubilisation de medicaments
PT1660047E (pt) 2003-08-13 2014-02-27 Biocon Ltd Formulação de dosagem sólida de sais de ácidos gordos em micropartículas para agentes terapêuticos
KR20080009201A (ko) 2005-04-15 2008-01-25 클라루스 쎄러퓨틱스, 아이엔씨. 소수성 약물의 약물전달시스템 및 이를 포함하는 조성물
US8492369B2 (en) 2010-04-12 2013-07-23 Clarus Therapeutics Inc Oral testosterone ester formulations and methods of treating testosterone deficiency comprising same
ES2383303T3 (es) 2005-11-10 2012-06-20 Chemi S.P.A. Formulaciones de inhibidores de la liberación prolongada de la hormona del crecimiento análogos de la somatostatina
ITMI20060618A1 (it) 2006-03-31 2007-10-01 Enitecnologie Spa Procedimento per la preparazione di nanoemulsioni acqua ion olio e olio in acqua
EP1961412A1 (fr) 2006-12-27 2008-08-27 LEK Pharmaceuticals D.D. Systèmes auto-microémulsifiants pour l'administration de médicaments
GB0716385D0 (en) * 2007-08-22 2007-10-03 Camurus Ab Formulations
US11304960B2 (en) 2009-01-08 2022-04-19 Chandrashekar Giliyar Steroidal compositions
ES2424492T3 (es) * 2009-07-30 2013-10-02 Evonik Röhm Gmbh Composición pulverulenta o granulada que comprende un copolímero, una sal de un ácido monocarboxílico graso y un ácido monocarboxílico graso y/o un alcohol graso
IE20100174A1 (en) * 2010-03-25 2012-02-29 Trinity College Dublin Transdermal administration of peptides
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
WO2016033549A2 (fr) 2014-08-28 2016-03-03 Lipocine Inc. Compositions de (17-ss)-3-oxoandrost-4-èn-17-yl tridécanoate et leurs procédés de préparation et d'utilisation
WO2016033556A1 (fr) 2014-08-28 2016-03-03 Lipocine Inc. Esters de (17-β)-hydroxy-4-androstène-3-one biodisponibles à l'état solide
US20180147215A1 (en) 2016-11-28 2018-05-31 Lipocine Inc. Oral testosterone undecanoate therapy
AU2018236349B2 (en) 2017-03-15 2021-03-11 Cerecin Inc. Pharmaceutical compositions having high drug loadings of medium chain triglycerides and methods related thereto
WO2019161263A1 (fr) * 2018-02-16 2019-08-22 Ohio State Innovation Foundation Nanoparticules de lipide-tensioactif pour l'administration de médicament, et leurs procédés de fabrication et d'utilisation
US20200215027A1 (en) * 2018-12-28 2020-07-09 Robert K. Prud'homme Dihydromyricetin nanoemulsion formulations and methods for forming them
AU2022283278A1 (en) * 2021-05-25 2024-01-18 Cerecin Inc. Stable liquid pharmaceutical compositions having high drug loadings of medium chain triglycerides and methods related thereto
CN113952301A (zh) * 2021-11-17 2022-01-21 胡振华 中链脂肪酸作为促吸收剂制备药物组合物乳剂的应用

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4146499A (en) * 1976-09-18 1979-03-27 Rosano Henri L Method for preparing microemulsions
EP0278660A1 (fr) * 1987-02-03 1988-08-17 Stiefel Laboratories (Ireland) Limited Microémulsions
EP0387647A2 (fr) * 1989-03-13 1990-09-19 Desitin Arzneimittel GmbH Composition pharmaceutique à haute dispersion
WO1991018669A1 (fr) * 1990-06-08 1991-12-12 Affinity Biotech, Inc. Procede servant a preparer des microemulsions
WO1992018147A1 (fr) * 1991-04-19 1992-10-29 Affinity Biotech, Inc. Formulations de microemulsions a inversion de phase

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1171125A (en) * 1966-06-08 1969-11-19 Glaxo Lab Ltd Improvements in or relating to Injectable Preparations
FR2502951B1 (fr) * 1981-04-06 1985-12-06 Sandoz Sa Compositions pharmaceutiques topiques sous forme d'une micro-emulsion
DE3406497A1 (de) * 1984-02-23 1985-09-05 Mueller Bernhard Willi Werner Hochdisperse pharmazeutische mehrkomponentensysteme und verfahren zu ihrer herstellung

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4146499A (en) * 1976-09-18 1979-03-27 Rosano Henri L Method for preparing microemulsions
EP0278660A1 (fr) * 1987-02-03 1988-08-17 Stiefel Laboratories (Ireland) Limited Microémulsions
EP0387647A2 (fr) * 1989-03-13 1990-09-19 Desitin Arzneimittel GmbH Composition pharmaceutique à haute dispersion
WO1991018669A1 (fr) * 1990-06-08 1991-12-12 Affinity Biotech, Inc. Procede servant a preparer des microemulsions
WO1992018147A1 (fr) * 1991-04-19 1992-10-29 Affinity Biotech, Inc. Formulations de microemulsions a inversion de phase

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9408610A1 *

Also Published As

Publication number Publication date
JPH08505367A (ja) 1996-06-11
EP0671937A1 (fr) 1995-09-20
WO1994008610A1 (fr) 1994-04-28

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 19950510

AK Designated contracting states

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Designated state(s): BE CH DE FR GB IT LI NL

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Ipc: A61K 37/00

A4 Supplementary search report drawn up and despatched

Effective date: 19960730

AK Designated contracting states

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18D Application deemed to be withdrawn

Effective date: 19990205