EP0493434A4 - Tsh receptor - Google Patents
Tsh receptorInfo
- Publication number
- EP0493434A4 EP0493434A4 EP19900913766 EP90913766A EP0493434A4 EP 0493434 A4 EP0493434 A4 EP 0493434A4 EP 19900913766 EP19900913766 EP 19900913766 EP 90913766 A EP90913766 A EP 90913766A EP 0493434 A4 EP0493434 A4 EP 0493434A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- tsh receptor
- tsh
- receptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US40489989A | 1989-09-08 | 1989-09-08 | |
US404899 | 1989-09-08 | ||
US56566990A | 1990-08-10 | 1990-08-10 | |
US565669 | 1990-08-10 |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0493434A1 EP0493434A1 (en) | 1992-07-08 |
EP0493434A4 true EP0493434A4 (en) | 1993-05-05 |
Family
ID=27018824
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP19900913766 Withdrawn EP0493434A4 (en) | 1989-09-08 | 1990-09-07 | Tsh receptor |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0493434A4 (ja) |
JP (1) | JP3181582B2 (ja) |
CA (1) | CA2066263C (ja) |
WO (1) | WO1991003483A1 (ja) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU5732190A (en) * | 1989-05-05 | 1990-11-29 | Genentech Inc. | Glycoprotein hormone receptor molecules |
US6261800B1 (en) | 1989-05-05 | 2001-07-17 | Genentech, Inc. | Luteinizing hormone/choriogonadotropin (LH/CG) receptor |
US5744348A (en) * | 1989-09-08 | 1998-04-28 | New England Medical Center Hospitals, Inc. | TSH receptor |
US5614363A (en) * | 1990-01-25 | 1997-03-25 | New England Medical Center Hospitals, Inc. | TSH receptor |
EP0433509B1 (en) * | 1989-12-14 | 1996-11-13 | B.R.A.H.M.S Diagnostica GmbH | Polypeptides having thyrotropin receptor activity, nucleic acid sequences coding for such receptors and polypeptides, and applications of these polypeptides |
EP0506890A4 (en) * | 1989-12-20 | 1993-06-30 | Nichols Institute Diagnostics | Recombinant thyrotropin receptor |
DE19645729C1 (de) * | 1996-11-06 | 1998-06-04 | Brahms Diagnostica Gmbh | Rezeptorbindungsassay, für den Rezeptorbindungsassay geeigneter rekombinanter Fusionsrezeptor, Vektor zu dessen Herstellung sowie Reagenziensatz für die Durchführung des Rezeptorbindungsassays |
DE19651093C2 (de) * | 1996-12-09 | 1999-06-10 | Brahms Diagnostica Gmbh | Rezeptorbindungsassay zum Nachweis von TSH-Rezeptor-Autoantikörpern sowie Reagenziensatz für die Durchführung eines solchen Rezeptorbindungsassays |
EP1017709A4 (en) * | 1997-09-24 | 2001-12-12 | Merck & Co Inc | HOMMAL GLYCOPROTEIC RECEPTOR AOMF05 COUPLED BY G PROTEINS |
GB9823397D0 (en) | 1998-10-27 | 1998-12-23 | Rsr Ltd | Assays for thyroid autoantibodies |
DE50306067D1 (de) | 2002-11-26 | 2007-02-01 | Brahms Ag | Nachweis von tsh-rezeptor-autoantikörpern mit affinitätsgereinigten antikörpern |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990013643A2 (en) * | 1989-05-05 | 1990-11-15 | Genentech, Inc. | Glycoprotein hormone receptor molecules |
WO1991009121A2 (en) * | 1989-12-14 | 1991-06-27 | Henning Berlin Gmbh Chemie- Und Pharmawerk | Polypeptides having thyrotropin-receptor activity, nucleic acid sequences coding for such receptors and polypeptides, and applications of these polypeptides |
WO1991009137A1 (en) * | 1989-12-20 | 1991-06-27 | Basil Rapoport | Recombinant thyrotropin receptor |
WO1991010735A2 (fr) * | 1990-01-15 | 1991-07-25 | Institut National De La Sante Et De La Recherche Medicale | Recepteur humain de la tsh. sequence codant pour ce recepteur |
-
1990
- 1990-09-07 CA CA002066263A patent/CA2066263C/en not_active Expired - Fee Related
- 1990-09-07 WO PCT/US1990/005066 patent/WO1991003483A1/en not_active Application Discontinuation
- 1990-09-07 JP JP51304090A patent/JP3181582B2/ja not_active Expired - Fee Related
- 1990-09-07 EP EP19900913766 patent/EP0493434A4/en not_active Withdrawn
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990013643A2 (en) * | 1989-05-05 | 1990-11-15 | Genentech, Inc. | Glycoprotein hormone receptor molecules |
WO1991009121A2 (en) * | 1989-12-14 | 1991-06-27 | Henning Berlin Gmbh Chemie- Und Pharmawerk | Polypeptides having thyrotropin-receptor activity, nucleic acid sequences coding for such receptors and polypeptides, and applications of these polypeptides |
WO1991009137A1 (en) * | 1989-12-20 | 1991-06-27 | Basil Rapoport | Recombinant thyrotropin receptor |
WO1991010735A2 (fr) * | 1990-01-15 | 1991-07-25 | Institut National De La Sante Et De La Recherche Medicale | Recepteur humain de la tsh. sequence codant pour ce recepteur |
Non-Patent Citations (8)
Title |
---|
64TH MEETING OF THE AMERICAN THYROID ASSOCIATION, 1989, abstract no. T-51; L. FRAZIER-SEABROOK et al.: "Isolation of a thyroid-specific cDNA with over 80% aminoacid homology with the luteinizing hormone receptor" * |
ACTA ENDOCRINOLOGICA, vol. 115, suppl. 281, 1987, pages 166-172, Copenhagen, DK; J. CHAN et al.: "TSH receptor structure" * |
BIOCHEM. BIOPHYS. RES. COMMUN., vol. 165, no. 3, 29th December 1989, pages 1184-1190, Academic Press, New York, US; Y. NAGAYAMA et al.: "Molecular cloning, sequence and functional expression of the cDNA for the human thyrotropin receptor" * |
BIOCHEM. BIOPHYS. RES. COMMUN., vol. 165, no. 3, 29th December 1989, pages 1250-1255, Academic Press, New York, US; F. LIBERT et al.: "Cloning, sequencing and expression of the human thyrotropin (TSH) receptor: evidence for binding of autoantibodies" * |
CLINICAL RESEARCH, vol. 29, no. 2, April 1981, page 294A, Thorofare, NJ, US; M.N. ISLAM et al.: "Purification of the human thyrotropin receptor" * |
ENDOCRINOLOGY, vol. 110, no. 4, April 1982, pages 1381-1391, The Endocrine Soc., Baltimore, US; Y. KOIZUMI et al.: "Solubilisation, purification, and partial characterization of thyrotropin receptor from bovine and human thyroid glands" * |
SCIENCE, vol. 246, 22nd December 1989, pages 1620-1622, AAAS, Washington, DC, US; M. PARMENTIER et al.: "Molecular cloning of the thyroid receptor" * |
See also references of WO9103483A1 * |
Also Published As
Publication number | Publication date |
---|---|
CA2066263A1 (en) | 1991-03-09 |
EP0493434A1 (en) | 1992-07-08 |
JPH05501952A (ja) | 1993-04-15 |
JP3181582B2 (ja) | 2001-07-03 |
CA2066263C (en) | 1999-11-02 |
WO1991003483A1 (en) | 1991-03-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19920310 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB IT LI LU NL SE |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 19930316 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB IT LI LU NL SE |
|
17Q | First examination report despatched |
Effective date: 19950613 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION HAS BEEN WITHDRAWN |
|
18W | Application withdrawn |
Withdrawal date: 20010618 |