EP0386109A1 - Knochenbildungssbeschleunigung durch gm-csf - Google Patents
Knochenbildungssbeschleunigung durch gm-csfInfo
- Publication number
- EP0386109A1 EP0386109A1 EP88910226A EP88910226A EP0386109A1 EP 0386109 A1 EP0386109 A1 EP 0386109A1 EP 88910226 A EP88910226 A EP 88910226A EP 88910226 A EP88910226 A EP 88910226A EP 0386109 A1 EP0386109 A1 EP 0386109A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- bone
- csf
- treatment
- stimulators
- administration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/23—Calcitonins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/193—Colony stimulating factors [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/29—Parathyroid hormone (parathormone); Parathyroid hormone-related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11961187A | 1987-11-12 | 1987-11-12 | |
US119611 | 1987-11-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
EP0386109A1 true EP0386109A1 (de) | 1990-09-12 |
Family
ID=22385326
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP88910226A Pending EP0386109A1 (de) | 1987-11-12 | 1988-11-10 | Knochenbildungssbeschleunigung durch gm-csf |
EP88310594A Withdrawn EP0318184A1 (de) | 1987-11-12 | 1988-11-10 | Knochenbildungbeschleunigung durch GM-CSF |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP88310594A Withdrawn EP0318184A1 (de) | 1987-11-12 | 1988-11-10 | Knochenbildungbeschleunigung durch GM-CSF |
Country Status (6)
Country | Link |
---|---|
EP (2) | EP0386109A1 (de) |
JP (1) | JPH0649655B2 (de) |
AU (1) | AU638204B2 (de) |
DK (1) | DK116390A (de) |
IL (1) | IL88344A (de) |
WO (1) | WO1989004173A1 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE89737T1 (de) * | 1989-01-30 | 1993-06-15 | Schering Corp | Behandlung von leukozytstoerungen mit gm-csf. |
NZ236618A (en) | 1990-01-03 | 1997-06-24 | Ciba Geigy Ag | Treating and preventing osteoporosis using insulin-like growth factor i (igf i) in conjunction with a bone antiresorptive active compound |
US5206023A (en) * | 1991-01-31 | 1993-04-27 | Robert F. Shaw | Method and compositions for the treatment and repair of defects or lesions in cartilage |
US5118667A (en) * | 1991-05-03 | 1992-06-02 | Celtrix Pharmaceuticals, Inc. | Bone growth factors and inhibitors of bone resorption for promoting bone formation |
JPH0517367A (ja) * | 1991-07-08 | 1993-01-26 | Green Cross Corp:The | 骨粗鬆症治療剤 |
US5270300A (en) * | 1991-09-06 | 1993-12-14 | Robert Francis Shaw | Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone |
DE69233329T2 (de) * | 1991-12-18 | 2004-08-05 | Icu Medical, Inc., Irvine | Verfahren zum Flüssigkeitstransfer |
TW267102B (de) | 1992-03-13 | 1996-01-01 | Ciba Geigy | |
SE9702401D0 (sv) | 1997-06-19 | 1997-06-19 | Astra Ab | Pharmaceutical use |
EP0891779A1 (de) * | 1997-06-19 | 1999-01-20 | Roche Diagnostics GmbH | Pharmazeutische Kombinationspräparate enthaltend Parathyroidhormon und Calcium- und/oder Phosphatverbindungen |
JP4709440B2 (ja) * | 2001-08-20 | 2011-06-22 | 高山産業株式会社 | 通気路形成用のスペーサーおよびそのスペーサーを用いた壁体の通気路形成方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR893138A (fr) * | 1940-04-05 | 1944-05-31 | Procédé de préparation d'un produit destiné à guérir les fractures des os | |
IL78342A (en) * | 1985-04-04 | 1991-06-10 | Gen Hospital Corp | Pharmaceutical composition for treatment of osteoporosis in humans comprising a parathyroid hormone or a fragment thereof |
US5078996A (en) * | 1985-08-16 | 1992-01-07 | Immunex Corporation | Activation of macrophage tumoricidal activity by granulocyte-macrophage colony stimulating factor |
DE3545568A1 (de) * | 1985-12-21 | 1987-07-16 | Hoechst Ag | Gm-csf-protein, seine derivate, herstellung solcher proteine und ihre verwendung |
AU626530B2 (en) * | 1987-07-17 | 1992-08-06 | Schering Biotech Corporation | Human granulocyte-macrophage colony stimulating factor and muteins thereof |
-
1988
- 1988-11-10 WO PCT/US1988/003922 patent/WO1989004173A1/en not_active Application Discontinuation
- 1988-11-10 IL IL8834488A patent/IL88344A/en not_active IP Right Cessation
- 1988-11-10 EP EP88910226A patent/EP0386109A1/de active Pending
- 1988-11-10 JP JP63509410A patent/JPH0649655B2/ja not_active Expired - Lifetime
- 1988-11-10 EP EP88310594A patent/EP0318184A1/de not_active Withdrawn
- 1988-11-10 AU AU27103/88A patent/AU638204B2/en not_active Ceased
-
1990
- 1990-05-10 DK DK116390A patent/DK116390A/da not_active Application Discontinuation
Non-Patent Citations (1)
Title |
---|
See references of WO8904173A1 * |
Also Published As
Publication number | Publication date |
---|---|
DK116390D0 (da) | 1990-05-10 |
WO1989004173A1 (en) | 1989-05-18 |
AU638204B2 (en) | 1993-06-24 |
IL88344A0 (en) | 1989-06-30 |
DK116390A (da) | 1990-05-10 |
EP0318184A1 (de) | 1989-05-31 |
IL88344A (en) | 1994-06-24 |
AU2710388A (en) | 1989-06-01 |
JPH02502642A (ja) | 1990-08-23 |
JPH0649655B2 (ja) | 1994-06-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Nakamura et al. | Recombinant human basic fibroblast growth factor accelerates fracture healing by enhancing callus remodeling in experimental dog tibial fracture | |
US7638486B2 (en) | Method for promoting hard tissue formation | |
Foster et al. | Advances in defining regulators of cementum development and periodontal regeneration | |
AU599031B2 (en) | Regulation of degradation processes in bone | |
Wang et al. | Thrombin peptide (TP508) promotes fracture repair by up‐regulating inflammatory mediators, early growth factors, and increasing angiogenesis | |
Guizzardi et al. | Polydeoxyribonucleotide (PDRN) promotes human osteoblast proliferation: a new proposal for bone tissue repair | |
JPH09510209A (ja) | 骨の成長を刺激するための繊維芽細胞成長因子の用途 | |
EP0386109A1 (de) | Knochenbildungssbeschleunigung durch gm-csf | |
Yamashita et al. | Effects of Intermittent Administration of Parathyroid Hormone and Parathyroid Hormone Related Protein on Fracture Healing: A Narrative Review of Animal and Human Studies | |
Lucas et al. | Stimulation of systemic bone formation induced by experimental blood loss. | |
EP1313440B1 (de) | Dentalzubereitungen enthaltend peptide, die das knochenwachstum fördern | |
Bail et al. | Recombinant species-specific growth hormone increases hard callus formation in distraction osteogenesis | |
Yao et al. | CCL2 is a critical mechano-responsive mediator in crosstalk between osteoblasts and bone mesenchymal stromal cells | |
Schneider et al. | The anabolic effects of vitamin D-binding protein-macrophage activating factor (DBP-MAF) and a novel small peptide on bone | |
Feng et al. | Small blood stem cells for enhancing early osseointegration formation on dental implants: a human phase I safety study | |
WO2015057836A2 (en) | Bone anabolic parathyroid hormone and parathyroid hormone related-protein analogs | |
CN111632147A (zh) | 骨细胞Wnt激活剂在制备骨折加速愈合、防治骨不连及不运动或失重骨丢失药物中的应用 | |
Gandhi et al. | Platelet releasate enhances healing in patients with a non-union | |
Laurina et al. | Growth factors/cytokines/defensins and apoptosis in periodontal pathologies | |
Yuli et al. | Effect of Aloe vera gel on the expression of FGF-2, TGF-β, and Smad3 in the root surface of rat teeth after Traumatic avulsion | |
Drakopoulos et al. | Off-label use of teriparatide in spine | |
Chunxiao et al. | Pharmacological effects of a recombinant hPTH (1− 34) derived peptide on ovariectomized rats | |
Morshed et al. | Fracture healing | |
JPH07504160A (ja) | 骨の再生 | |
US20160220639A1 (en) | Methods and compositions for treating bone diseases |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
|
17P | Request for examination filed |
Effective date: 19900515 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE FR GB IT LI LU NL SE |
|
XX | Miscellaneous (additional remarks) |
Free format text: VERFAHREN ABGESCHLOSSEN INFOLGE VERBINDUNG MIT 88310594.2/0318184 (EUROPAEISCHE ANMELDENUMMER/VEROEFFENTLICHUNGSNUMMER) VOM 24.04.91. |