EP0218696A4 - Menschliches antientzündungs-phospholipase-inhibitorprotein. - Google Patents

Menschliches antientzündungs-phospholipase-inhibitorprotein.

Info

Publication number
EP0218696A4
EP0218696A4 EP19860902722 EP86902722A EP0218696A4 EP 0218696 A4 EP0218696 A4 EP 0218696A4 EP 19860902722 EP19860902722 EP 19860902722 EP 86902722 A EP86902722 A EP 86902722A EP 0218696 A4 EP0218696 A4 EP 0218696A4
Authority
EP
European Patent Office
Prior art keywords
ignition
human anti
inhibitor protein
phospholipase inhibitor
phospholipase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19860902722
Other languages
English (en)
French (fr)
Other versions
EP0218696A1 (de
Inventor
Lorin F Johnson
John P Longenecker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biotechnology Research Partners Ltd
Original Assignee
Biotechnology Research Partners Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotechnology Research Partners Ltd filed Critical Biotechnology Research Partners Ltd
Publication of EP0218696A1 publication Critical patent/EP0218696A1/de
Publication of EP0218696A4 publication Critical patent/EP0218696A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4721—Lipocortins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/71—Expression systems using regulatory sequences derived from the trp-operon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
EP19860902722 1985-04-15 1986-04-14 Menschliches antientzündungs-phospholipase-inhibitorprotein. Withdrawn EP0218696A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72304685A 1985-04-15 1985-04-15
US723046 1985-04-15

Publications (2)

Publication Number Publication Date
EP0218696A1 EP0218696A1 (de) 1987-04-22
EP0218696A4 true EP0218696A4 (de) 1989-08-16

Family

ID=24904592

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19860902722 Withdrawn EP0218696A4 (de) 1985-04-15 1986-04-14 Menschliches antientzündungs-phospholipase-inhibitorprotein.

Country Status (6)

Country Link
EP (1) EP0218696A4 (de)
JP (2) JP2757987B2 (de)
AU (1) AU5770786A (de)
CA (1) CA1290267C (de)
ES (1) ES8800691A1 (de)
WO (1) WO1986006100A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4879224A (en) * 1985-01-10 1989-11-07 Biogen, Inc. DNA sequences, recombinant DNA molecules and processes for producing human phospholipase inhibitor polypeptides
US4874743A (en) * 1985-01-10 1989-10-17 Biogen, Inc. DNA sequences, recombinant DNA molecules and processes for producing human phospholipase inhibitor-like polypeptides
AU601676B2 (en) * 1985-01-10 1990-09-20 Biogen, Inc. Dna sequences recombinant dna molecules and processes for producing human lipocorton-like polypeptides
US5081019A (en) * 1985-01-10 1992-01-14 Biogen, Inc. DNA sequences, recombinant DNA molecules and processes for producing lipocortin-like polypeptides
US4950646A (en) * 1985-01-10 1990-08-21 Biogen, Inc. DNA sequences, recombinant DNA molecules and processes for producing human lipocortin-like polypeptides
JPS6256429A (ja) * 1985-09-04 1987-03-12 Teijin Ltd フオスフオリパ−ゼａ↓２阻害活性を有する蛋白
PT87083B (pt) * 1987-03-28 1992-07-31 Boehringer Ingelheim Int Processo para a preparacao de uma proteina anticoagulante vascular, de adn que codifica para esta proteina e de composicoes farmaceuticas que a contem
JPH06799B2 (ja) * 1987-04-02 1994-01-05 帝人株式会社 起炎性フオスフオリパ−ゼａ▲下２▼阻害活性を有する蛋白
DE68923107T2 (de) * 1988-02-26 1996-01-18 Biogen Inc DNA-Sequenzen, rekombinante DNA-Moleküle und Verfahren zur Herstellung von Lipocortin III, IV, V, und VI.
US5519120A (en) * 1989-04-07 1996-05-21 Cancerforskningsfondet Af 1989 Urokinase-type plasminogen activator receptor antibodies
DE69033653T2 (de) * 1989-04-07 2001-06-07 Cancerforskningsfonden Af 1989 (Fonden Til Fremme Af Eksperimental Cancerforskning), Kopenhagen Plasminogen-aktivator-rezeptor vom urokinasetyp
US5891664A (en) * 1989-04-07 1999-04-06 Cancerforskningsfondet Af 1989 Vectors and methods for recombinant production of uPA-binding fragments of the human urokinase-type plasminogen receptor (uPAR)
US5344764A (en) * 1989-08-03 1994-09-06 Teijin Limited Protein inhibitors of phospholipase A2 purified from inflammatory sites and production process
WO1991001999A1 (fr) * 1989-08-03 1991-02-21 Teijin Limited Proteine d'inhibition de la phospholipase a2 naissant dans une region inflammee, sa production et gene prevu a cet effet
WO1991003544A1 (en) * 1989-08-29 1991-03-21 The Regents Of The University Of California Novel hydrolytic enzyme inhibitors and substrates and assays, methods and kits embodying same
DE69432608T2 (de) 1993-06-01 2004-02-26 Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville Expression von inhibitoren vom plasminogenaktivator vom urokinasetyp
US6248715B1 (en) 1993-06-01 2001-06-19 Chiron Corporation Method of treating a urokinase-type plasminogen activator-mediated disorder
AU7036398A (en) * 1997-03-20 1998-10-20 Fondazione Centro San Raffaele Del Monte Tabor Upar mimicking peptide

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986004094A1 (en) * 1985-01-10 1986-07-17 Biogen .N.V. Dna sequences, recombinant dna molecules and processes for producing human lipocortin-like polypeptides
EP0213916A2 (de) * 1985-09-04 1987-03-11 Teijin Limited Protein mit Phospholipase-A2 hemmender Aktivität

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986004094A1 (en) * 1985-01-10 1986-07-17 Biogen .N.V. Dna sequences, recombinant dna molecules and processes for producing human lipocortin-like polypeptides
EP0213916A2 (de) * 1985-09-04 1987-03-11 Teijin Limited Protein mit Phospholipase-A2 hemmender Aktivität

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO8606100A1 *

Also Published As

Publication number Publication date
ES8800691A1 (es) 1987-11-16
JPS63500561A (ja) 1988-03-03
JP2637709B2 (ja) 1997-08-06
JP2757987B2 (ja) 1998-05-25
CA1290267C (en) 1991-10-08
JPH08187087A (ja) 1996-07-23
EP0218696A1 (de) 1987-04-22
ES553961A0 (es) 1987-11-16
AU5770786A (en) 1986-11-05
WO1986006100A1 (en) 1986-10-23

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19870109

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE FR GB IT LI LU NL SE

RIN1 Information on inventor provided before grant (corrected)

Inventor name: JOHNSON, LORIN, F.

Inventor name: LONGENECKER, JOHN, P.

A4 Supplementary search report drawn up and despatched

Effective date: 19890816

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19901103

RIN1 Information on inventor provided before grant (corrected)

Inventor name: LONGENECKER, JOHN, P.

Inventor name: JOHNSON, LORIN, F.