EP0150172A2 - Blood-sampling tube - Google Patents
Blood-sampling tube Download PDFInfo
- Publication number
- EP0150172A2 EP0150172A2 EP85890006A EP85890006A EP0150172A2 EP 0150172 A2 EP0150172 A2 EP 0150172A2 EP 85890006 A EP85890006 A EP 85890006A EP 85890006 A EP85890006 A EP 85890006A EP 0150172 A2 EP0150172 A2 EP 0150172A2
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- EP
- European Patent Office
- Prior art keywords
- tube
- cap
- closure element
- jacket
- heat
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5082—Test tubes per se
- B01L3/50825—Closing or opening means, corks, bungs
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D51/00—Closures not otherwise provided for
- B65D51/002—Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means
Definitions
- the invention relates to a sealed, evacuable blood sample tube for a blood collection device with a hollow cylindrical holder, which has a double-ended hollow needle at one end and in the other, open end of which the blood sample tube can be inserted to such an extent that one needle end pierces the seal.
- a closure element which is adjacent to a sealing membrane made of rubber-elastic material, for example Silicone rubber, is arranged and that of a flat, preferably constant wall thickness film, e.g. consists of aluminum, which is provided on its side facing the inside of the tube with a continuous heat-sealable layer.
- a tube for a vacuum blood collection system is known from DE-OS 29 08 817.
- the closure element there forms a screw-on cap, which has an opening, the edge of which presses a membrane forming the seal from a material which can be pierced by one end of the needle, sealingly against the open end of the blood sample tube.
- threads have to be made at its opening and at its closure cap, and furthermore, when the cap is screwed on, a careful sealing of the membrane between the cap and the end of the tube must be made.
- Access to the sample taken with such a tube ultimately requires unscrewing the cap again, which is cumbersome and time consuming; moreover, it cannot be determined from the tube whether an unwanted opening has been carried out.
- a tube similar to the type mentioned is known from DE-OS 22 43 593.
- a metal cap shaped in the manner of a crown fastener is provided, which has a circular crown part in its central part and then an outwardly hanging cuff with an inverted U-profile, which ends in an upturned edge.
- the central part of the circular crown part is designed with a smaller thickness in order to be easily pierced by the hollow needle.
- At least the inner surface of the metal cap, preferably its entire lower surface, is covered with a thin protective coating made of vinyl in order to prevent contamination of the tube contents.
- the seal is attached to the outer surface of the metal cap, and the cap with its U-profile is attached to the end of the tube using a hot-melt material, such as polyamide, which forms an adhesive bond between the butt surface of the sleeve and the outer surface of the tube end.
- a hot-melt material such as polyamide
- the tube of the latter type is improved according to AT-PS 368 389 in that the closure consists of a flat, preferably constant wall thickness film, which is provided on one side with a continuous heat-sealable layer, which provides a tight connection between the film and the Forms end face of the tube and insulates the interior of the tube against the film.
- a tube in which the closure element carries the sealing membrane on the outside that this closure element is fixed by means of the heat-sealable layer on a flange of a cap having a double jacket, which cap has the open end of Includes tube inside and outside and is stored in this by means of a press fit.
- a cap with a double jacket is provided, which is attached to the end of the tube, and the double jacket provides a particularly good seal with the tube, so that vacuum losses are avoided.
- this cap can in turn be used to very easily close the blood samples by simply pushing them into the tube, so that this enables closed storage.
- the object of the invention is to eliminate the difficulties mentioned even in the case of evacuable tubes made of glass.
- the closure element is fixed by means of the heat-sealable layer on the end face of a cap having a double jacket, which covers the open end of the tube from the outside, and in that the sealing membrane which is arranged on the heat-sealable layer of the closure element is also designed as a cap having a double jacket, the outer jacket of which rests against the inside of the end of the tube and which receives the inner jacket of the closure element cap, the caps being mounted on the end of the tube by means of a press fit.
- two caps each having a double jacket, are thus provided, and are inserted such that the open end of the tube is surrounded on the outside by the inner surface of the outer jacket of the closure element cap and on the inside by the outer surface of the outer jacket of the sealing membrane cap. This ensures one excellent tightness against the inside of the tube when it has been placed under vacuum.
- heat-sealable layer is also connected to the end face of the sealing membrane cap.
- the strength of the end wall of the sealing membrane cap is increased in this way.
- the outer jacket of the closure element cap is longer than the sealing membrane cap. This causes an increased strength of the outer jacket of the closure element cap.
- a last feature of the invention is that protrusions, e.g. V-ribs are arranged, which engage in the central part of the cap designed as a directional cushion. This results in an increased bond effect between the two nested caps.
- the plastic outer cap 1 here the cylindrical element, which carries the closure element, has an outer jacket 2, an end wall 3 and an inner jacket 4.
- This inner jacket 4 is provided on its inner surface with two circumferential V-ribs 5.
- the end face 3 of the cap 1 carries the closure element 6, which is formed in the form of a circuit board from an aluminum foil 8 provided with a heat-sealing layer 7 and having a constant wall thickness.
- Such films are known per se.
- a 0.3 mm thick aluminum foil is expediently used.
- the closure element 6 is firmly and tightly connected to the end wall 3 of the cap 1 via the layer 7 by its heat sealing.
- Adjacent to the closure element 6 or its hot seal Gel layer 7 is also provided within the inner shell 4 of the outer cap 1, an approximately 2-4 mm thick sealing pad 9, which consists of a rubber-elastic material, preferably silicone rubber, and forms the central part of a further, inner sealing membrane cap 10.
- This second cap 10 has an inner, downwardly extending jacket 11, following the cushion 9, and an outer, outer jacket 12 at the end thereof. The arrangement is such that the inner cap 10 is inserted into the outer cap 1 at the bottom, such that the inner shell 4 of the outer cap 1 lies between the outer shell 12 on the one hand and the inner shell 11 or cushion 9 of the inner cap 10.
- an annular space remains between the inner surface of the outer shell 2 of the cap 1 and the outside of the outer shell 12 of the inner cap 10, which is intended to receive the free end 13 of the tube 14 made of glass.
- the cap 10 made of the elastic material resiliently deforms due to the press fit of the two caps 1, 10 on the end 13 of the tube 14, so that a particularly good seal of the tube interior can be achieved when this is evacuated and then stored under vacuum until use.
- the sealing pad 9 vulcanized onto the cap 1 in an airtight manner has the property that when one end of the double-ended needle of the hollow cylindrical holder is pierced and the needle is withdrawn again after the blood has been drawn, it closes completely.
- the outside of the outer jacket 2 of the cap 1 can, as shown, be provided with grooves 15.
- the tube 14 can also consist of plastic. It is also possible to provide a plastic film 8 on the closure element 6 see.
- the layer 7 can also be heat-sealed with the cushion 9.
- the cap 1 expediently consists of thermoplastic or thermosetting plastic, e.g. impact-resistant polystyrene, polypropylene, thermoplastic polyesters or polyamides, polymethyl methacrylate or the like.
- thermoplastic or thermosetting plastic e.g. impact-resistant polystyrene, polypropylene, thermoplastic polyesters or polyamides, polymethyl methacrylate or the like.
- the inner cap 10 is shaped by injection molding, preferably into the outer cap 1.
- the tube designed according to the invention can be used not only for taking blood, but also for taking or storing other body fluids or infusion solutions and also for similar purposes.
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Devices For Use In Laboratory Experiments (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
Dieses mit einer Dichtung verschlossene, evakuierbare Blutprobenröhrchen (14) ist für ein Blutabnahmegerät mit einem hohlzylindrischen Harter bestimmt, der an einem Ende eine doppelendige Hohlnadel aufweist und in dessen anderes, offenes Ende das Blutprobenröhrchen (14) soweit einschiebbar ist, daß das eine Nadelende die Dichtung durchstößt. Dabei ist das Röhrchen (14) an seinem offenen Ende (13) durch ein Verschlußelement (6) abgedeckt, das benachbart zu einer diese Dichtung bildenden Dichtungsmembran (9) aus gummielastischem Werkstoff, z.B. Silikonkautschuk, angeordnet ist und das aus einer ebenen, vorzugsweise gleichbleibende Wandstärke aufweisenden Folie, z.B. aus Aluminium, besteht. Diese Folie ist an ihrer dem Röhrcheninneren zugewandten Seite mit einer durchgehenden heißsiegelbaren Schicht (7) versehen. Um eine besonders hohe Vakuumdichtheit, auch bei Herstellungstoleranzen aufweisenden, insbesondere aus Glas hergestellten Röhrchen (14) zu erhalten, ist das Verschlußelement (6) mittels der heißsiegelbaren Schicht (7) an der Stirnfläche (3) einer einen Doppelmantel (2, 4) aufweisenden Kappe (1) festgelegt. Diese Kappe (1) umfaßt das offene Ende (13) des Röhrchens (14) von außen. Die anschließend an die heißsiegelbare Schicht (7) des Verschlußelementes (6) angeordnete Dichtungsmembran (9) ist ebenfalls als eine einen Doppelmantel aufweisende Kappe (10) ausgebildet, deren Außenmantel (12) an der Innenseite des Endes (13) des Röhrchens (14) anliegt und die den Innenmantel (4) der Verschlußelementkappe (1) aufnimmt. Beide Kappen (1, 10) sind mittels Preßsitz am Ende (13) des Röhrchens (14) gelagert.This sealed with a seal, evacuable blood sample tube (14) is intended for a blood collection device with a hollow cylindrical harder, which has a double-ended hollow needle at one end and in the other, open end of the blood sample tube (14) can be inserted so far that one end of the needle Seal pierces. The tube (14) is covered at its open end (13) by a closure element (6) which is adjacent to a sealing membrane (9) which forms this seal and is made of rubber-elastic material, e.g. Silicone rubber, is arranged and that from a flat, preferably constant wall thickness film, e.g. made of aluminum. This film is provided on its side facing the inside of the tube with a continuous heat-sealable layer (7). In order to obtain a particularly high vacuum tightness, even in the case of tubes (14) having manufacturing tolerances, in particular made of glass, the closure element (6) is provided with a double jacket (2, 4) on the end face (3) by means of the heat-sealable layer (7) Cap (1) set. This cap (1) encompasses the open end (13) of the tube (14) from the outside. The sealing membrane (9) which is arranged next to the heat-sealable layer (7) of the closure element (6) is likewise designed as a cap (10) having a double jacket, the outer jacket (12) of which on the inside of the end (13) of the tube (14) abuts and which receives the inner jacket (4) of the closure element cap (1). Both caps (1, 10) are press-fitted at the end (13) of the tube (14).
Description
Die Erfindung bezieht sich auf ein mit einer Dichtung verschlossenes, evakuierbares Blutprobenröhrchen für ein Blutabnahmegerät mit einem hohlzylindrischen Halter, der an einem Ende eine doppelendige Hohlnadel aufweist und in dessen anderes, offenes Ende das Blutprobenröhrchen soweit einschiebbar ist, daß das eine Nadelende die Dichtung durchstößt, wobei das Röhrchen an seinem offenen Ende durch ein Verschlußelement abgedeckt ist, das benachbart zu einer Dichtungsmembran aus gummielastischem Werkstoff, z.B. Silikonkautschuk, angeordnet ist und das aus einer ebenenen, vorzugsweise gleichbleibende Wandstärke aufweisenden Folie, z.B. aus Aluminium besteht, die an ihrer dem Röhrcheninneren zugewandten Seite mit einer durchgehenden heißsiegelbaren Schicht versehen ist.The invention relates to a sealed, evacuable blood sample tube for a blood collection device with a hollow cylindrical holder, which has a double-ended hollow needle at one end and in the other, open end of which the blood sample tube can be inserted to such an extent that one needle end pierces the seal. wherein the tube is covered at its open end by a closure element, which is adjacent to a sealing membrane made of rubber-elastic material, for example Silicone rubber, is arranged and that of a flat, preferably constant wall thickness film, e.g. consists of aluminum, which is provided on its side facing the inside of the tube with a continuous heat-sealable layer.
Ein Röhrchen für ein Vakuum-Blutentnahmesystem ist aus der DE-OS 29 08 817 bekannt. Das Verschlußelement bildet dort eine aufschraubbare Kappe, die eine öffnung aufweist, deren Rand eine die Dichtung bildende Membrane aus einem Material, das vom einen Ende der Nadel durchstechbar ist, an das offene Ende des Blutprobenröhrchens abdichtend andrückt. Bei diesem Röhrchen müssen also an seiner Öffnung und an seiner Verschlußkappe Gewinde hergestellt werden, und ferner muß beim Aufschrauben der Kappe eine sorgfältige Dichtung der Membrane zwischen der Kappe und dem Röhrchenende hergestellt werden. Der Zugang zu der mit einem solchen Röhrchen entnommenen Probe erfordert letztlich wieder das Abschrauben der Kappe, was umständlich und zeitraubend ist; außerdem kann am Röhrchen nicht festgestellt werden, ob ein ungewolltes Offnen vorgenommen ist. Ferner hat sich herausgestellt, daß bei längerer Lagerung dieser Röhrchen, insbesondere wenn sie aus mikroporösem Kunststoff bestehen, das Vakuum nicht mehr oder nur mehr ungenügend vorhanden ist.A tube for a vacuum blood collection system is known from DE-OS 29 08 817. The closure element there forms a screw-on cap, which has an opening, the edge of which presses a membrane forming the seal from a material which can be pierced by one end of the needle, sealingly against the open end of the blood sample tube. With this tube, therefore, threads have to be made at its opening and at its closure cap, and furthermore, when the cap is screwed on, a careful sealing of the membrane between the cap and the end of the tube must be made. Access to the sample taken with such a tube ultimately requires unscrewing the cap again, which is cumbersome and time consuming; moreover, it cannot be determined from the tube whether an unwanted opening has been carried out. Furthermore, it has been found that when these tubes are stored for a prolonged period, particularly if they are made of microporous plastic, the vacuum is no longer or only insufficiently present.
Ein Röhrchen ähnlich der eingangs genannten Art ist aus der DE-OS 22 43 593 bekannt. Bei einer besonderen Ausführungsform wird dabei eine nach Art eines Kronenverschlusses geformte Metallkappe vorgesehen, die in ihrem Mittelteil einen kreisförmigen Kronenteil und daran nach außen anschließend eine ringförmige herabhängende Manschette mit umgekehrtem U-Profil aufweist, das in einen nach oben umgekröpften Rand endet. Der Mittelteil des kreisförmigen Kronenteiles ist mit geringerer Dicke ausgebildet, um leicht von der Hohlnadel durchstochen werden zu können. Wenigstens die Innenfläche der Metallkappe, vorzugsweise ihre gesamte Unterfläche, ist dabei mit einem dünnen Schutzüberzug aus Vinyl überzogen, um eine Verunreinigung des Röhrcheninhaltes hintanzuhalten. Die Dichtung ist an der Außenfläche der Metallkappe befestigt,und die Festlegung der Kappe mit ihrem U-Profil am Röhrchenende erfolgt mit Hilfe eines heißschmelzenden Materials, wie Polyamid, das eine Klebebindung zwischen der Stoßfläche der Manschette und der Außenfläche des Rohrendes bildet. In dieser Weise kann die Metallkappe mit einem Kronenkorkenöffner abgenommen werden. Auch diese bekannte Lösung weist nicht nur eine Vielzahl von kompliziert geformten bzw. herzustellenden Einzelteilen auf, sondern auch einen umständlichen Aufwand beim Zusammenbau und bei der Handhabung.A tube similar to the type mentioned is known from DE-OS 22 43 593. In a special embodiment, a metal cap shaped in the manner of a crown fastener is provided, which has a circular crown part in its central part and then an outwardly hanging cuff with an inverted U-profile, which ends in an upturned edge. The central part of the circular crown part is designed with a smaller thickness in order to be easily pierced by the hollow needle. At least the inner surface of the metal cap, preferably its entire lower surface, is covered with a thin protective coating made of vinyl in order to prevent contamination of the tube contents. The seal is attached to the outer surface of the metal cap, and the cap with its U-profile is attached to the end of the tube using a hot-melt material, such as polyamide, which forms an adhesive bond between the butt surface of the sleeve and the outer surface of the tube end. In this way, the metal cap can be removed with a crown cap opener. This known solution also not only has a large number of intricately shaped or to be produced individual parts, but also a complicated outlay in terms of assembly and handling.
Das Röhrchen der letzterwähnten Art wird nach der AT-PS 368 389 dadurch verbessert, daß der Verschluß aus einer ebenen, vorzugsweise gleichbleibende Wandstärke aufweisenden Folie, besteht, die einseitig mit einer durchgehenden heißsiegelbaren Schicht versehen ist, welche eine dichte Verbindung zwischen der Folie und der Endstirnfläche des Röhrchens bildet und den Röhrcheninnenraum gegen die Folie isoliert.The tube of the latter type is improved according to AT-PS 368 389 in that the closure consists of a flat, preferably constant wall thickness film, which is provided on one side with a continuous heat-sealable layer, which provides a tight connection between the film and the Forms end face of the tube and insulates the interior of the tube against the film.
Nach einem eigenen, nicht zum Stand der Technik gehörenden Vorschlag, ist bei einem Röhrchen, bei dem das Verschlußelement außen die Dichtungsmembrane trägt, vorgesehen, daß dieses Verschlußelement mittels der heißsiegelbaren Schicht an einem Flansch einer einen Doppelmantel aufweisenden Kappe festgelegt ist, die das offene Ende des Röhrchens von innen und außen umfaßt und mittels Preßsitz in diesem gelagert ist. Nach dem Wesen dieses Vorschlages ist sohin eine Kappe mit Doppelmantel vorgesehen, die an das Ende des Röhrchens aufgesteckt ist, und es wird durch den Doppelmantel eine besonders gute Abdichtung zum Röhrchen erzielt, sodaß damit Vakuumverluste vermieden werden. Weiters kann man mit dieser Kappe wiederum sehr leicht durch einfaches Eindrücken in das Röhrchen die Blutproben verschließen, so daß damit ein verschlossenes Aufbewahren ermöglicht wird.According to its own proposal, which is not part of the prior art, it is provided in a tube in which the closure element carries the sealing membrane on the outside that this closure element is fixed by means of the heat-sealable layer on a flange of a cap having a double jacket, which cap has the open end of Includes tube inside and outside and is stored in this by means of a press fit. According to the nature of this proposal, a cap with a double jacket is provided, which is attached to the end of the tube, and the double jacket provides a particularly good seal with the tube, so that vacuum losses are avoided. Furthermore, this cap can in turn be used to very easily close the blood samples by simply pushing them into the tube, so that this enables closed storage.
Wiewohl sich solche Röhrchen ausgezeichnet bewährt haben, wenn sie aus Kunststoff bestehen, ergeben sich manchmal Schwierigkeiten, wenn sie aus Glas bestehen, da die dann erheblichen Herstellungstoleranzen im Innen- und Außendurchmesser des offenen Röhrchenendes bezüglich der geforderten hohen Vakuumdichtheit schwer zu beherrschen sind.Although such tubes have proven to be excellent when they are made of plastic, difficulties sometimes arise when they are made of glass, since the then considerable manufacturing tolerances in the inside and outside diameter of the open tube end are difficult to control with regard to the high vacuum tightness required.
Von diesem bekannten Stand der Technik ausgehend, stellt sich die Erfindung die Aufgabe, die genannten Schwierigkeiten auch bei aus Glas bestehenden, evakuierbaren Röhrchen zu beseitigen.Starting from this known state of the art, the object of the invention is to eliminate the difficulties mentioned even in the case of evacuable tubes made of glass.
Die Lösung dieser Aufgabe besteht gemäß der Erfindung darin, daß das Verschlußelement mittels der heißsiegelbaren Schicht an der Stirnfläche einer einen Doppelmantel aufweisenden Kappe festgelegt ist, die das offene Ende des Röhrchens von außen umfaßt, und daß die anschließend an die heißsiegelbare Schicht des Verschlußelementes angeordnete Dichtungsmembran ebenfalls als eine einen Doppelmantel aufweisende Kappe ausgebildet ist, deren Außenmantel an der Innenseite des Endes des Röhrchens anliegt und die den Innenmantel der Verschlußelementkappe aufnimmt, wobei die Kappen mittels Preßsitz am Ende des Röhrchens gelagert sind.This object is achieved according to the invention in that the closure element is fixed by means of the heat-sealable layer on the end face of a cap having a double jacket, which covers the open end of the tube from the outside, and in that the sealing membrane which is arranged on the heat-sealable layer of the closure element is also designed as a cap having a double jacket, the outer jacket of which rests against the inside of the end of the tube and which receives the inner jacket of the closure element cap, the caps being mounted on the end of the tube by means of a press fit.
Nach dem Wesen der Erfindung werden also zwei jeweils einen Doppelmantel aufweisende Kappen vorgesehen, und zwar so ineinandergesteckt, daß das offene Ende des Röhrchens außen von der Innenfläche des Außenmantels der Verschlußelementkappe und innen von der Außenfläche des Außenmantels der Dichtungsmembrankappe umfaßt ist. Dies sichert eine hervorragende Dichtheit gegenüber dem Röhrcheninneren, wenn dieses unter Vakuum gesetzt worden ist.According to the essence of the invention, two caps, each having a double jacket, are thus provided, and are inserted such that the open end of the tube is surrounded on the outside by the inner surface of the outer jacket of the closure element cap and on the inside by the outer surface of the outer jacket of the sealing membrane cap. This ensures one excellent tightness against the inside of the tube when it has been placed under vacuum.
Ein weiteres Merkmal der Erfindung ist, daß die heißsiegelbare Schicht auch mit der Stirnfläche der Dichtungsmembrankappe verbunden ist. Beim Durchstechen mit der Hohlnadel wird in dieser Weise die Festigkeit der Stirnwand der Dichtungsmembrankappe erhöht.Another feature of the invention is that the heat-sealable layer is also connected to the end face of the sealing membrane cap. When piercing with the hollow needle, the strength of the end wall of the sealing membrane cap is increased in this way.
Ferner ist es von Vorteil, daß der Außenmantel der Verschlußelementkappe länger ist als die Dichtungsmembrankappe. Dies bewirkt eine erhöhte Festigkeit des Außenmantels der Verschlußelementkappe.It is also advantageous that the outer jacket of the closure element cap is longer than the sealing membrane cap. This causes an increased strength of the outer jacket of the closure element cap.
Ein letztes Merkmal der Erfindung ist, daß an der Innenseite der Verschlußelementkappe Vorragungen, z.B. Keilrippen, angeordnet sind, die in den als Richtungspolster ausgebildeten Mittelteil der Kappe eingreifen. So ergibt sich eine erhöhte Verbundwirkung zwischen den beiden ineinanderliegenden Kappen.A last feature of the invention is that protrusions, e.g. V-ribs are arranged, which engage in the central part of the cap designed as a directional cushion. This results in an increased bond effect between the two nested caps.
Weitere Einzelheiten der Erfindung ergeben sich aus der folgenden Beschreibung eines Ausführungsbeispieles anhand der Zeichnung, in deren einziger Figur eine das Verschlußelement tragende äußere und die zugehörige innere Kappe, aufgesteckt auf ein Blutprobenröhrchen, im Vertikalschnitt bzw. zum Teil in Seitenansicht, dargestellt sind.Further details of the invention will become apparent from the following description of an exemplary embodiment with reference to the drawing, in the single figure of which an outer cap carrying the closure element and the associated inner cap, attached to a blood test tube, are shown in vertical section or partly in side view.
Die aus Kunststoff bestehende äußere, das Verschlußelement tragende Kappe 1, hier zylindrischer Form, weist einen äußeren Mantel 2, eine Stirnwand 3 und einen inneren Mantel 4 auf. Dieser innere Mantel 4 ist an seiner Innenfläche mit zwei umfänglich verlaufenden Keilrippen 5 versehen. Die Stirnfläche 3 der Kappe 1 trägt das Verschlußelement 6, das in Form einer Platine aus einer mit einer Heißsiegelschicht 7 versehenen, gleichbleibende Wandstärke aufweisenden Aluminiumfolie 8 ausgebildet ist. Solche Folien sind an sich bekannt. Zweckmäßig wird eine 0,3 mm starke Aluminiumfolie verwendet.The plastic
Das Verschlußelement 6 ist über die Schicht 7 durch deren Heißsiegelung fest und dicht mit der Stirnwand 3 der Kappe 1 verbunden.The
Benachbart zum Verschlußelement 6 bzw. seiner Heißsiegelschicht 7 ist innerhalb des Innenmantels 4 der äußeren Kappe 1 ferner ein etwa 2 - 4 mm starkes Dichtungspolster 9 vorgesehen, das aus einem gummielastischen Werkstoff, vorzugsweise Silikonkautschuk, besteht und den Mittelteil einer weiteren, inneren Dichtungsmembrankappe 10 bildet. Diese zweite Kappe 10 weist nämlich, anschließend an das Polster 9, einen inneren, sich nach unten erstreckenden Mantel 11 und an dessen Ende einen sich wieder nach oben erstreckenden äußeren Mantel 12 auf. Die Anordnung ist dabei so getroffen, daß die Innenkappe 10 unten in die Außenkappe 1 gesteckt ist, dergestalt, daß der Innenmantel 4 der Außenkappe 1 zwischen dem Außenmantel 12 einerseits und dem Innenmantel 11 bzw. Polster 9 der Innenkappe 10 liegt. So verbleibt zwischen der Innenfläche des Außenmantels 2 der Kappe 1 und der Außenseite des Außenmantels 12 der Innenkappe 10 ein Ringraum, der dazu bestimmt ist, das freie Ende 13 des aus Glas bestehenden Röhrchens 14 aufzunehmen.Adjacent to the
Es ist erkenntlich, daß sich in dieser Weise die aus dem elastischen Werkstoff bestehende Kappe 10 nachgiebig verformt, bedingt durch den Preßsitz der beiden Kappen 1, 10 auf dem Ende 13 des Röhrchens 14, sodaß eine besonders gute Dichtung des Röhrcheninnenraumes erzielbar ist, wenn dieses evakuiert wird und sodann unter Vakuum bis zum Gebrauch aufbewahrt wird.It can be seen that in this way the
Das luftdicht der Kappe 1 aufvulkanisierte Dichtungspolster 9 hat die Eigenschaft, daß es sich, wenn man das eine Ende der doppelendigen Nadel des hohlzylindrischen Halters hindurchsticht und die Nadel nach der Blutabnahme wieder herauszieht, wieder ganz schließt.The
Die Außenseite des Außenmantels 2 der Kappe 1 kann, wie dargestellt, mit Riefen 15 versehen sein.The outside of the
Die Handhabung und Wirkungsweise dieses Röhrchens bezüglich der Blutabnahme ist wie in der genannten DE-OS 2 908 817 beschrieben.The handling and mode of operation of this tube with regard to blood collection is as described in the aforementioned DE-OS 2 908 817.
An dem beschriebenen Ausführungsbeispiel können Abänderungen vorgenommen werden. So kann das Röhrchen 14 z.B. auch aus Kunststoff bestehen. Es ist ferner möglich, am Verschlußelement 6 auch eine Folie 8 aus Kunststoff vorzusehen. Die Schicht 7 kann auch mit dem Polster 9 heißgesiegelt sein.Modifications can be made to the exemplary embodiment described. For example, the
Anstelle der Ringrippen 5 können auch zur besseren Verankerung mit dem Polster 9 am Innenmantel 4 der Kappe 1 einzelne Fortsätze beliebiger Formgestaltung vorgesehen werden, z.B. als Walzen, Halbkugeln, Pyramiden, od.dgl.Instead of the ring ribs 5, individual extensions of any shape can also be provided for better anchoring with the
Zweckmässig besteht die Kappe 1 aus thermoplastischem oder duroplastischem Kunststoff, z.B. schlagfestem Polystyrol, Polypropylen, thermoplastischen Polyestern oder Polyamiden, Polymethylmethacrylat od.dgl.The
Die Formgebung der Innenkappe 10 erfolgt durch Spritzgießen, vorzugsweise in die Außenkappe 1.The
Das erfindungsgemäß ausgebildete Röhrchen kann nicht nur zur Blutentnahme, sondern auch zur Entnahme oder Aufbewahrung von anderen Körperflüssigkeiten oder Infusionslösungen und auch für dazu ähnliche Zwecke eingesetzt werden.The tube designed according to the invention can be used not only for taking blood, but also for taking or storing other body fluids or infusion solutions and also for similar purposes.
Claims (4)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT61/84 | 1984-01-11 | ||
AT0006184A AT379069B (en) | 1984-01-11 | 1984-01-11 | BLOOD SAMPLES |
Publications (3)
Publication Number | Publication Date |
---|---|
EP0150172A2 true EP0150172A2 (en) | 1985-07-31 |
EP0150172A3 EP0150172A3 (en) | 1985-08-21 |
EP0150172B1 EP0150172B1 (en) | 1988-10-05 |
Family
ID=3480487
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP85890006A Expired EP0150172B1 (en) | 1984-01-11 | 1985-01-11 | Blood-sampling tube |
Country Status (11)
Country | Link |
---|---|
US (1) | US4652429A (en) |
EP (1) | EP0150172B1 (en) |
JP (1) | JPS60242367A (en) |
AT (1) | AT379069B (en) |
AU (1) | AU568179B2 (en) |
BR (1) | BR8500108A (en) |
CA (1) | CA1234770A (en) |
DE (1) | DE3565365D1 (en) |
ES (1) | ES292754Y (en) |
IL (1) | IL74024A (en) |
ZA (1) | ZA85194B (en) |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0295750A1 (en) * | 1987-06-17 | 1988-12-21 | Hendrik Dr. Kruijswijk | Safety means for blood collection systems |
WO1989009735A1 (en) * | 1988-04-15 | 1989-10-19 | C.A. Greiner & Söhne Gesellschaft M.B.H. | Closure device for an in particular evacuable cylindrical housing |
EP0454493A2 (en) * | 1990-04-26 | 1991-10-30 | Charles Terrence Macartney | Reinsertable closure for sample tubes |
US5275299A (en) * | 1988-04-15 | 1994-01-04 | C. A. Greiner & Sohne Gesellschaft Mbh | Closure device for an in particular evacuable cylindrical housing |
EP0623523A1 (en) * | 1993-05-06 | 1994-11-09 | Becton, Dickinson and Company | Combination stopper-shield closure |
EP0634339A1 (en) * | 1993-06-29 | 1995-01-18 | Becton, Dickinson and Company | Combination stopper-shield closure |
AT403369B (en) * | 1988-04-15 | 1998-01-26 | Greiner & Soehne C A | Closure arrangement for a cylindrical housing which, in particular, may be evacuated |
US7097057B2 (en) | 1999-12-23 | 2006-08-29 | Helvoet Pharma Belgium N.V. | Closure device for a vacuum sample collector |
WO2020231474A3 (en) * | 2018-12-17 | 2021-03-11 | Sio2 Medical Products, Inc. | Container and cap assembly for cryogenic storage |
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AT380392B (en) * | 1985-01-24 | 1986-05-12 | C A Greiner & S Hne Ges M B H | BLOOD SAMPLING! |
CA1236788A (en) * | 1985-04-17 | 1988-05-17 | Canadian Industrial Innovation Centre/Waterloo | Containers for culturing and testing of vertebrate lenses |
WO1988004154A1 (en) * | 1986-12-11 | 1988-06-16 | Terumo Kabushiki Kaisha | Blood sampling tube |
US4789639A (en) * | 1987-01-02 | 1988-12-06 | Becton, Dickinson And Company | Liquid recovery device |
JPS63315033A (en) * | 1987-06-18 | 1988-12-22 | Terumo Corp | Method and apparatus for collecting blood specimen |
JPH01219667A (en) * | 1988-02-29 | 1989-09-01 | Sanraizu Syst:Kk | Vessel for collecting blood |
DE3806875C1 (en) * | 1988-03-03 | 1989-11-16 | Franz Pohl, Metall- Und Kunststoffwarenfabrik Gmbh, 7500 Karlsruhe, De | |
AT391951B (en) * | 1988-12-23 | 1990-12-27 | Greiner & Soehne C A | Closure device for a housing |
US4896780A (en) * | 1988-05-09 | 1990-01-30 | Multi-Technology Inc. | Fail safe releasible locks for capped disposable centrifuge containers |
US4874102A (en) * | 1988-05-09 | 1989-10-17 | Multi-Technology Inc. | Medical fail safe releasible locks and/or seals for capped disposable centrifuge containers, cryogenic vials and the like |
US4953741A (en) * | 1988-05-09 | 1990-09-04 | Multi-Technology Inc. | Medical fail safe releasible locks and/or seals for capped disposable centrifuge containers, cryogenic vials and the like |
US4956103A (en) * | 1988-05-09 | 1990-09-11 | Multi-Technology Inc. | Fail safe releasible locks for capped disposable centrifuge containers |
US4830209A (en) * | 1988-05-09 | 1989-05-16 | Multi-Technology Inc. | Fail safe releasible locks for cappped disposable centrifuge containers |
JPH0260869U (en) * | 1988-10-28 | 1990-05-07 | ||
AT401341B (en) * | 1990-03-09 | 1996-08-26 | Greiner & Soehne C A | LOCKING DEVICE FOR A PARTICULARLY EVACUABLE HOUSING |
IT1274578B (en) * | 1992-05-13 | 1997-07-17 | Francesco Leopardi | SAFETY CLOSURE DEVICE FOR CONTAINERS FOR ORGANIC LIQUIDS |
US5871700A (en) * | 1993-12-21 | 1999-02-16 | C.A. Greiner & Sohne Gesellschaft M.B.H. | Holding device with a cylindrical container and blood sampling tube with such a holding device |
DE19703921C1 (en) * | 1997-02-03 | 1999-03-18 | Sarstedt Walter Geraete | Blood collection device |
US5897840A (en) * | 1997-07-16 | 1999-04-27 | Battelle Memorial Institute | Multi-chambered urine specimen container for automatic extraction and high forensic integrity |
US6565814B1 (en) * | 1998-03-18 | 2003-05-20 | Sekisui Chemical Co., Ltd. | Closure structure for vacuum specimen collection container, vacuum specimen collection container, vacuum specimen collection system, holder for vacuum specimen collection system and thermoplastic elastomer composition for forming closure structure |
US6716396B1 (en) * | 1999-05-14 | 2004-04-06 | Gen-Probe Incorporated | Penetrable cap |
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- 1985-01-08 IL IL74024A patent/IL74024A/en unknown
- 1985-01-09 AU AU37531/85A patent/AU568179B2/en not_active Ceased
- 1985-01-09 ZA ZA85194A patent/ZA85194B/en unknown
- 1985-01-10 US US06/690,148 patent/US4652429A/en not_active Expired - Fee Related
- 1985-01-10 BR BR8500108A patent/BR8500108A/en unknown
- 1985-01-10 ES ES1985292754U patent/ES292754Y/en not_active Expired
- 1985-01-11 CA CA000471968A patent/CA1234770A/en not_active Expired
- 1985-01-11 JP JP60002250A patent/JPS60242367A/en active Pending
- 1985-01-11 EP EP85890006A patent/EP0150172B1/en not_active Expired
- 1985-01-11 DE DE8585890006T patent/DE3565365D1/en not_active Expired
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Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0295750A1 (en) * | 1987-06-17 | 1988-12-21 | Hendrik Dr. Kruijswijk | Safety means for blood collection systems |
WO1989009735A1 (en) * | 1988-04-15 | 1989-10-19 | C.A. Greiner & Söhne Gesellschaft M.B.H. | Closure device for an in particular evacuable cylindrical housing |
US5275299A (en) * | 1988-04-15 | 1994-01-04 | C. A. Greiner & Sohne Gesellschaft Mbh | Closure device for an in particular evacuable cylindrical housing |
US5522518A (en) * | 1988-04-15 | 1996-06-04 | C.A. Greiner & Sohne Gesellschaft M.B.H | Closure device for a cylindrical housing |
AT403369B (en) * | 1988-04-15 | 1998-01-26 | Greiner & Soehne C A | Closure arrangement for a cylindrical housing which, in particular, may be evacuated |
EP0454493A2 (en) * | 1990-04-26 | 1991-10-30 | Charles Terrence Macartney | Reinsertable closure for sample tubes |
EP0454493A3 (en) * | 1990-04-26 | 1992-05-13 | Charles Terrence Macartney | Reinsertable closure for sample tubes |
EP0623523A1 (en) * | 1993-05-06 | 1994-11-09 | Becton, Dickinson and Company | Combination stopper-shield closure |
EP0634339A1 (en) * | 1993-06-29 | 1995-01-18 | Becton, Dickinson and Company | Combination stopper-shield closure |
US7097057B2 (en) | 1999-12-23 | 2006-08-29 | Helvoet Pharma Belgium N.V. | Closure device for a vacuum sample collector |
WO2020231474A3 (en) * | 2018-12-17 | 2021-03-11 | Sio2 Medical Products, Inc. | Container and cap assembly for cryogenic storage |
Also Published As
Publication number | Publication date |
---|---|
EP0150172A3 (en) | 1985-08-21 |
ZA85194B (en) | 1985-08-28 |
CA1234770A (en) | 1988-04-05 |
ES292754Y (en) | 1987-03-01 |
EP0150172B1 (en) | 1988-10-05 |
AT379069B (en) | 1985-11-11 |
JPS60242367A (en) | 1985-12-02 |
IL74024A (en) | 1988-07-31 |
ES292754U (en) | 1986-06-16 |
ATA6184A (en) | 1984-10-15 |
IL74024A0 (en) | 1985-04-30 |
AU568179B2 (en) | 1987-12-17 |
BR8500108A (en) | 1985-08-20 |
DE3565365D1 (en) | 1988-11-10 |
AU3753185A (en) | 1985-07-18 |
US4652429A (en) | 1987-03-24 |
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