EP0109434A1 - Procedes diagnostics in vitro utilisant des anticorps monoclonaux contre les proteines des tissus connectifs - Google Patents

Procedes diagnostics in vitro utilisant des anticorps monoclonaux contre les proteines des tissus connectifs

Info

Publication number
EP0109434A1
EP0109434A1 EP83902045A EP83902045A EP0109434A1 EP 0109434 A1 EP0109434 A1 EP 0109434A1 EP 83902045 A EP83902045 A EP 83902045A EP 83902045 A EP83902045 A EP 83902045A EP 0109434 A1 EP0109434 A1 EP 0109434A1
Authority
EP
European Patent Office
Prior art keywords
connective tissue
collagen
cell
human
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP83902045A
Other languages
German (de)
English (en)
Other versions
EP0109434A4 (fr
Inventor
Steffen Gay
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP0109434A1 publication Critical patent/EP0109434A1/fr
Publication of EP0109434A4 publication Critical patent/EP0109434A4/fr
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

On décrit des anticorps monoclonaux contre les protéines des tissus connectifs, pouvant être utilisés pour déterminer le profil de collagène d'échantillons de fluides biologiques, d'échantillons cytologiques et d'échantillons hystologiques. Des combinaisons de ces anticorps monoclonaux peuvent être utilisées dans un but diagnostique ou thérapeutique.
EP19830902045 1982-05-19 1983-05-16 Procedes diagnostics in vitro utilisant des anticorps monoclonaux contre les proteines des tissus connectifs. Ceased EP0109434A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37970482A 1982-05-19 1982-05-19
US379704 1982-05-19

Publications (2)

Publication Number Publication Date
EP0109434A1 true EP0109434A1 (fr) 1984-05-30
EP0109434A4 EP0109434A4 (fr) 1986-09-23

Family

ID=23498331

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19830902045 Ceased EP0109434A4 (fr) 1982-05-19 1983-05-16 Procedes diagnostics in vitro utilisant des anticorps monoclonaux contre les proteines des tissus connectifs.

Country Status (8)

Country Link
EP (1) EP0109434A4 (fr)
CA (1) CA1251729A (fr)
ES (1) ES522508A0 (fr)
GR (1) GR78570B (fr)
MX (1) MX197328A (fr)
NZ (1) NZ204255A (fr)
WO (1) WO1983004104A1 (fr)
ZA (1) ZA833483B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4628027A (en) * 1982-05-19 1986-12-09 Molecular Engineering Associates, Ltd. Vitro diagnostic methods using monoclonal antibodies against connective tissue proteins
SE8304836D0 (sv) * 1983-09-09 1983-09-09 Pharmacia Ab Sett att bestemma forendringar i ledbrosk
GB2205643B (en) * 1987-05-08 1991-03-13 Farmos Group Limited Type iii collagen degradation assay
US6110689A (en) 1994-01-21 2000-08-29 Osteometer A/S Method of assaying collagen fragments in body fluids, a test kit and means for carrying out the method and use of the method to diagnose the presence of disorders associated with the metabolism of collagen
WO1996012193A1 (fr) 1994-10-17 1996-04-25 Osteometer Bio Tech A/S Evaluation du schema de fragmentation du collagene dans des fluides corporels et diagnostic des troubles associes au metabolisme du collagene
GB9506050D0 (en) 1995-03-24 1995-05-10 Osteometer A S Assaying collagen fragments in body fluids
WO1996012192A1 (fr) * 1994-10-18 1996-04-25 Amdl, Inc. Anticorps anti-complexes de matrices extracellulaires et leur utilisation dans la detection du cancer
US6107047A (en) * 1996-03-21 2000-08-22 Osteometer Biotech A/S Assaying protein fragments in body fluids
GB9617616D0 (en) 1996-08-22 1996-10-02 Osteometer Biotech As Assaying protein fragments in body fluids
EP0944833B1 (fr) 1996-12-09 2001-06-27 Osteometer Biotech AS Dosages en sandwich de fragments de collagene
EP0878480A1 (fr) * 1997-05-14 1998-11-18 H.W. Prof. Dr. Müller Procédé pour ameliorer la régénération nerveuse
US6117646A (en) * 1997-09-22 2000-09-12 Osteometer Biotech A/S Assaying protein fragments in body fluids

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2816841A1 (de) * 1978-04-18 1979-10-31 Max Planck Gesellschaft Radioimmunologische bestimmung von prokollagen (typ iii) und prokollagen- peptid (typ iii)

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 106, no. 1, 14th May 1982, pages 48-57, Academic Press, Inc.; N. SUNDARRAJ et al.: "Development and characterization of monoclonal antibodies to human type III procollagen" *
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 92, no. 2, 29th January 1980, pages 440-446, Academic Press, Inc.; T.F. LINSENMAYER et al.: "Monoclonal antibodies to connective tissue macromolecules: type II collagen" *
FEDERATION PROCEEDINGS, vol. 40, no. 3, part 1, 1981, page 794, abstract no. 3213; H. FOELLMER et al.: "Monoclonal antibodies to type IV collagen from human placenta and bovine lung" *
FEDERATION PROCEEDINGS, vol. 41, no. 3, 1982, page 616, abstract no. 2027; H.G. FOELLMER et al.: "Production and characterization of monoclonal antibodies to type V collagen from human placental villi" *
PROC. NATL. ACAD. SCI. USA, vol. 76, no. 8, August 1979, pages 3703-3707; T.F. LINSENMAYER et al.: "Production and characterization of a monoclonal antibody to chicken type I collagen" *
See also references of WO8304104A1 *

Also Published As

Publication number Publication date
GR78570B (fr) 1984-09-27
CA1251729A (fr) 1989-03-28
NZ204255A (en) 1986-10-08
WO1983004104A1 (fr) 1983-11-24
ES8501630A1 (es) 1984-12-01
MX197328A (es) 1994-02-28
EP0109434A4 (fr) 1986-09-23
ES522508A0 (es) 1984-12-01
ZA833483B (en) 1984-06-27

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

AK Designated contracting states

Designated state(s): AT BE CH DE FR GB LI LU NL SE

17P Request for examination filed

Effective date: 19840326

A4 Supplementary search report drawn up and despatched

Effective date: 19860923

17Q First examination report despatched

Effective date: 19870716

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED

18R Application refused

Effective date: 19920807