EP0063472B1 - Composition de nettoyage pour des surfaces optiques et procédé pour nettoyer une lentille de contact - Google Patents

Composition de nettoyage pour des surfaces optiques et procédé pour nettoyer une lentille de contact Download PDF

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Publication number
EP0063472B1
EP0063472B1 EP82301936A EP82301936A EP0063472B1 EP 0063472 B1 EP0063472 B1 EP 0063472B1 EP 82301936 A EP82301936 A EP 82301936A EP 82301936 A EP82301936 A EP 82301936A EP 0063472 B1 EP0063472 B1 EP 0063472B1
Authority
EP
European Patent Office
Prior art keywords
cleansing composition
range
mixture
grams
polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
EP82301936A
Other languages
German (de)
English (en)
Other versions
EP0063472A2 (fr
EP0063472A3 (en
Inventor
Kai Chiang Su
Leslie Frank Stebbins
Rajkumar Pahlajrai Bhatia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Vision LLC
Original Assignee
Alcon Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Laboratories Inc filed Critical Alcon Laboratories Inc
Priority to AT82301936T priority Critical patent/ATE32270T1/de
Publication of EP0063472A2 publication Critical patent/EP0063472A2/fr
Publication of EP0063472A3 publication Critical patent/EP0063472A3/en
Application granted granted Critical
Publication of EP0063472B1 publication Critical patent/EP0063472B1/fr
Expired legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/0005—Other compounding ingredients characterised by their effect
    • C11D3/0078—Compositions for cleaning contact lenses, spectacles or lenses
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D17/00—Detergent materials or soaps characterised by their shape or physical properties
    • C11D17/0008—Detergent materials or soaps characterised by their shape or physical properties aqueous liquid non soap compositions
    • C11D17/0013—Liquid compositions with insoluble particles in suspension
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/37—Polymers

Definitions

  • This invention relates to a cleansing composition for optical surfaces such as contact lenses and similar optic apparatuses.
  • Cleansing compositions containing various abrasive materials have been used in the past.
  • the abradant material is added to the composition to increase the effectiveness of the composition in removing undesired matter from the surface being cleaned.
  • the abradants even when in fine particle form, were harsh and had a tendency to scratch optical surfaces.
  • Encrustations that form on contact lenses may be proteinaceous in nature or may be lipids or other materials foreign to the eye such as lady's mascara which usually is a soap or wax in gelatin. Success in wearing and properly using contact lenses is a function of maintaining them in a clean condition without the buildup of foreign matter, particularly encrustations which physically or chemically attach to the lens surface. Buildup of such material is gradual, but will ultimately render the lens opaque. Even before the lens becomes opaque, however, the presence of encrustations on the lens causes the wearer of the lens increased discomfort and irritation.
  • Hard contact lenses may be buffed to remove encrustations, but such a process requires skill and is not easily done by the user at home without the considerable danger of scratching the lens.
  • the surface of a soft contact lens is particularly prone to develop encrustations and presents particularly difficult cleaning problems since soft contact lenses cannot be cleaned except by professionals and then only with limited success.
  • compositions are primarily directed to disinfecting lenses and generally do not remove encrustations.
  • Those compositions that have been formulated for the purpose of removing encrustations have met with limited success.
  • Soft contact lenses may be divided into two broad categories, namely, hydrophilic and hydrophobic lenses.
  • Hydrophobic contact lenses are usually based on elastic and flexible silicone rubber (polysiloxane), and are generally made from cross-linked dimethyl polysiloxane.
  • Hydrophilic soft contact lenses are a hydrated gel, and the ability to absorb water results in swelling to a transparent soft mass of good mechanical strength which is very comfortable to the wearer.
  • Hydrated gel lenses can contain: hydroxyethylmethacrylate (HEMA) or its analogs, ethylene-glycol dimethacrylate (EGMA) or its analogs, polymethylmethacrylate (PMMA) or its analogs, polyvinylpyrrolidone (PVP) or its analogs, monomers, inhibitors, traces of catalysts and water. Hydrophilic groups of these plastic lenses attract and hold large amounts of water in the gel. These virtues, however, lead to difficulties in cleaning and sterilizing the lenses.
  • HEMA hydroxyethylmethacrylate
  • EGMA ethylene-glycol dimethacrylate
  • PMMA polymethylmethacrylate
  • PVP polyvinylpyrrolidone
  • Hydrophilic soft lenses may be disinfected by chemical treatment or by boiling. As indicated, neither procedure is entirely successful in removing encrustations. Some chemicals are ineffective in removing proteins, others in removing lipids. Boiling may even denature proteinaceous material on the lenses thereby attaching encrustations all the more firmly to the lenses.
  • United States Patent No. 3,910,296 to Karageozian et al. discusses a method for removing proteinaceous deposits from contact lenses with the use of a protease. However, lenses may become encrusted and contaminated with other deleterious materials such as lipids which protease enzyme will not remove.
  • the present invention provides a cleansing composition for cleaning optical surfaces comprising from 1 to 25% by weight of a particulate polymer which is an organic polymer, polysiloxane polymer or a mixture thereof wherein the polymer has a particle size in the range of from 1 to 600 micrometers and a Rockwell hardness in the range of from R30 to M105 or a Shore hardness in the range from A15 to D100, and a carrier comprising water and a thickener, which carrier is compatible with ocular tissue and has a viscosity sufficient to keep the particulate polymer in suspension.
  • a particulate polymer which is an organic polymer, polysiloxane polymer or a mixture thereof wherein the polymer has a particle size in the range of from 1 to 600 micrometers and a Rockwell hardness in the range of from R30 to M105 or a Shore hardness in the range from A15 to D100
  • a carrier comprising water and a thickener, which carrier is compatible with ocular tissue and has
  • the particulate polymer is mixed with a carrier containing a thickening agent such as Carbopol (a registered trademark of B. F. Goodrich Chemical Co.), cellulose, hydroxyethyl cellulose having a molecular weight of approximately 15,000 or polyethylene glycol with a molecular weight distribution of 400 to 4000 to form a suspension.
  • a carrier containing a thickening agent such as Carbopol (a registered trademark of B. F. Goodrich Chemical Co.), cellulose, hydroxyethyl cellulose having a molecular weight of approximately 15,000 or polyethylene glycol with a molecular weight distribution of 400 to 4000 to form a suspension.
  • the carrier can be any ocular compatible composition in which the polymeric particulates remain in suspension. Most generally the carrier is water to which various optional ingredients may be added.
  • the end product may be a fluid or may be a thixotropic ointment or gel.
  • a surfactant such as Pluronic, (a registered trademark of Wyandotte Chemicals Co.), Tween, (a registered trademark of Atlas Powder Company) or Tyloxapol (registered trademark) may optionally be added to the cleaning composition to increase its effectiveness.
  • Thimerosal a product of Eli ' Lilly & Co.
  • sorbic acid or ethylenediamintetraacetic acid (EDTA)
  • EDTA ethylenediamintetraacetic acid
  • preservatives or bactericides sodium chloride
  • purified water may be optionally employed as is known in the art to provide a sterile, buffered, isotonic cleaning composition for contact lenses.
  • the thickening agent is preferably present in an amount to give the suspension a viscosity of between about 150 and about 1500 mPas.
  • the thickener keeps the polymeric particles in suspension and any viscosity suspension that will accomplish this result may be used.
  • the polymeric particles are preferably spherical, have a particle size range preferably between about 20 and 100 micrometers, and preferably from 5 to 20 percent by weight of the suspension. A particle size above and below the 20 to 100 micrometer range will function; however, the smaller size particles will take longer to complete their cleaning function and larger particles will feel gritty to the user.
  • Nylon 6 which has the formula +CH 2 CH 2 CH 2 CH 2 CH 2 CO-NH+
  • Nylon 11 which has the formula ( ⁇ CH 2 (CH 2 ) 8 ⁇ CH 2 CO ⁇ NH) ⁇
  • Nylon 12 which has the formula ( ⁇ CH 2 (CH 2 ) 9 CH 2 CO ⁇ NH) ⁇ or mixtures thereof with Rockwell hardnesses of R80­83, R-108, and R-106, respectively, and particle size ranges of 1 to 80 pm, 1 to 80 ⁇ m and 20 to 45 pm, respectively, all may be used as polymeric particulates.
  • Nylon 11 is a preferred polymer.
  • Polyethylene glycol is a preferred thickener in amounts of between about 20 and about 80 percent by weight of the suspension, preferably between about 25 and about 50 percent by weight.
  • Nylon is a registered trade mark.
  • the following polymers with their hardnesses as indicated in Table 1 will serve as a suitable particulate polymer. * ASTM test method D785 applies to the Rockwell Hardness figure given, and ASTM test method D22450 applies to the Shore Hardness figures given.
  • Pluronic F-127 is a preferred surfactant and is an ethylene oxide-propylene oxide-propylene glycol condensation product sold by Wyandotte Chemical Corporation.
  • the surfactant as a 20% gel by weight in purified water is optionally added to the suspension in an amount of between about 5 to 15 percent by weight of the suspension, preferably between about 8 and about 12 percent by weight.
  • the particulate polymer, the polyethylene glycol and Pluronic F-127, as a 20% gel in purified water, may be mixed with Thimerosal, sorbic acid, EDTA, sodium chloride, and purified water to provide a sterile isotonic cleaning suspension.
  • polyethylene glycol having a molecular weight range from 400 to 4,000 is melted by suspending a suitable sized container, such as a beaker, containing the glycol in hot water.
  • a suitable sized container such as a beaker
  • the Pluronic F-127 is added with stirring until the mixture is cooled to room temperature.
  • the particulate polymer is added with stirring.
  • the optional salts and preservative are then added together with the required amount of water to provide a cleansing suspension of the desired viscosity.
  • the particulate polymer which is commercially purchased, has a range of particle sizes. A certain percentage of the substance may have a particle size below 5 or even 1 um. Hence, the particle sizes expressed in the Examples will be set forth as a range from between 0 and a size at the larger end of the range.
  • a mixture of 25 grams of polyethylene glycol of a molecular weight of approximatley 4000 and 30 grams of polyethylene glycol of a molecular weight of approximately 400 was melted and thoroughly mixed. With stirring 20 grams of a 20% gel in purified water of Pluronic F-127 was added to the polyethylene glycol mix. The resulting mixture was stirred until cooled to room temperature. Upon cooling 10 grams of Natural (10/ 15 ) ES (which is a trademark of Rislan Corporation and is Nylon-11 electrostatic extrude of a particle size range between 0 to 44 pm) was added with stirring to the polyethylene glycol and Pluronic mixture. With stirring 15 ml of purified water was added to the mixture and stirring was continued until a smooth suspension was formed.
  • Natural (10/ 15 ) ES which is a trademark of Rislan Corporation and is Nylon-11 electrostatic extrude of a particle size range between 0 to 44 pm
  • Example I 25 grams of Pluronic F-127 20% gel was added with stirring to a melted mixture of 25 grams of polyethylene glycol of a molecular weight of approximately 4000, and 30 grams of polyethylene glycol of a molecular weight of approximately 400. The resulting mixture was stirred until cooled to room temperature, whereupon 10 grams of Polymer H0050/80 (which is a trademark of Rislan Corporation and is Nylon-11 of a particle size range between 0 to 80 pm) was added with stirring to the polyethylene glycol and Pluronic mixture. With stirring 10 ml of purified water was added to the mixture and stirring was continued until a smooth suspension was formed.
  • Polymer H0050/80 which is a trademark of Rislan Corporation and is Nylon-11 of a particle size range between 0 to 80 pm
  • Example I 35 grams of Pluronic F-127 20% gel was added with stirring to a melted mixture of 25 grams of polyethylene glycol of a molecular weight of approximately 4000, and 30 grams of polyethylene glycol of a molecular weight of approximately 400. The resulting mixture was stirred until cooled to room temperature, whereupon 10 grams of French-Naturelle ES (which is a trademark of Rislan Corporation and is Nylon-11 electrostatic extrude of a particle size range between 0 to 80 pm) was added with stirring to the polyethylene glycol and Pluronic mixture. Stirring of the mixture was continued until a smooth suspension was formed.
  • French-Naturelle ES which is a trademark of Rislan Corporation and is Nylon-11 electrostatic extrude of a particle size range between 0 to 80 pm
  • Example I 35 grams of Pluronic F-127 20% gel was added with stirring to a melted mixture of 25 grams of polyethylene glycol of a molecular weight of approximately 4000, and 30 grams of polyethylene glycol of a molecular weight of approximately 400. The resulting mixture was stirred until cooled to room temperature, whereupon 10 grams of CAB 381-20 (which is a trademark of Eastman Chemical Co. and is cellulose acetate butyrate of a particle size range between 0 to 120 pm) was added to the polyethylene glycol and Pluronic mixture. Stirring of the mixture was continued until a smooth suspension was formed.
  • CAB 381-20 which is a trademark of Eastman Chemical Co. and is cellulose acetate butyrate of a particle size range between 0 to 120 pm
  • Example I 25 grams of Pluronic F-127 20% gel was added with stirring to a melted mixture of 25 grams of polyethylene glycol of a molecular weight of approximately 4000 and 30 grams of polyethylene glycol of a molecular weight of approximately 400. The resulting mixture was stirred until cooled to room temperature, whereupon 12.5 grams of Naturell Fine (which is a trademark of Rislan Corporation and is Nylon-11 of a particle size range between 0 to 45 pm) was added with stirring to the polyethylene glycol and Pluronic mixture. With constant agitation 0.02 grams of a 1.0% aqueous solution of Thimerosal and 0.9 grams of sodium chloride were mixed into the glycol-Pluronic-Naturell Fine mixture to form the cleaning composition. After addition of the Thimerosal and sodium chloride, with continued stirring purified water was added to bring the total weight of the composition to 100 grams and a smooth suspension was formed.
  • Naturell Fine which is a trademark of Rislan Corporation and is Nylon-11 of a particle size range between 0 to
  • Example I 25 grams of Pluronic F-127 20% gel was added with stirring to a melted mixture of 25 grams of polyethylene glycol of a molecular weight of approximately 4000 and 30 grams of polyethylene glycol of a molecular weight of approximately 400. The resulting mixture was stirred until cooled to room temperature, whereupon 10.0 grams of polyethylene F-N500 (which is a product of S. Industrial Chemicals and is low density polyethylene of a particle size of less than 20 pm) was added with stirring to the polyethylene glycol and Pluronic mixture. With constant agitation 0.02 grams of an aqueous solution of Thimerosal and 0.9 grams of sodium chloride were mixed into the glycol-Pluronic-polyethylene mixture to form the cleaning composition. After the addition of the Thimerosal and sodium chloride, with continuous stirring purified water was added to bring the total weight of the composition to 100 grams and a smooth suspension was formed.
  • polyethylene F-N500 which is a product of S. Industrial Chemicals and is low density polyethylene of a particle size
  • a mixture of 30 grams of polyethylene glycol of a molecular weight of approximately 4000 and 40 grams of polyethylene glycol of a molecular weight of approximately 400 was melted in a beaker by suspending the beaker into hot water. After the polyethylene glycol was completely melted, it was thoroughly mixed with a glass rod to form a smooth ointment base. The ointment base was transferred onto a porcelain tile and was mixed with a spatula with 15 grams of Natural ES (10/15) to form an ointment. With continued stirring purified water was incorporated into the ointment to bring the total weight of the composition to 100 grams and to soften and smooth the resulting cleansing ointment.
  • Example VIII A mixture of 50 grams of polyethylene glycol of a molecular weight of approximately 4000 and 30 grams of polyethylene glycol of a molecular weight of 400 was melted and mixed as in Example VIII. After mixing and melting, as in Example VIII, the glycol mixture was mixed with 10 grams of Natural ES and further mixed with purified water to bring the total weight of the composition to 100 grams and to provide a soft smooth cleansing ointment.
  • a mixture of 25 grams of polyethylene glycol of a molecular weight of approximately 4000, and 30 grams of polyethylene glycol of a molecular weight of 400 was melted and mixed as in Example VII. After mixing and melting, 25 grams of a 20% gel in purified water of Pluronic F-127 and 10 grams of polymer H0050/80 were added and mixed into the polyethylene glycol to provide an ointment. With continued mixing purified water was incorporated into the ointment to bring the total weight of the composition to 100 grams and to soften and smooth the resulting cleansing ointment.
  • Each brand of lenses was then cycled through a cleaning regimen.
  • the lens was rubbed with 2 to 3 drops of polymeric cleaner of Example VIII in the palm of the hand with the index finger for a total of 20 seconds and rinsed with normal saline. This procedure was repeated for a total of fifty cycles on each lens.
  • the lenses were viewed for scratches after 5,10,20,30,40 and 50 cleaning cycles using the Bausch & Lomb Optical Microscope under 20x and 100x magnifications. Photographs were taken.
  • the lens photographs indicate no sign of new cuts and/or scratches on the lens surfaces under study.
  • soft contact lenses were soiled with artificial deposition model solution, containing 0.05 percent by weight lysozyme 3x protein and 0.05% percent by weight mucin type 2 in isotonic solution to pH 7.0.
  • the deposition of clean lenses involved heating the lenses with a 5 ml of deposition model solution in stoppered glass vial for one hour at 92°C. The above procedure was repeated two times with fresh depositions model solution to obtain heavier deposits of protein on the lens surface.
  • the deposited lens was then rubbed with 2 to 3 drops of the polymer cleaner of Example VIII in the palm of the hand with the index finger for a total of 20 seconds (both sides of the lens) and rinsed with normal saline.
  • polymeric cleaner of Example VIII was needed to clean the protein from the lens.

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Detergent Compositions (AREA)
  • Eyeglasses (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Surface Treatment Of Optical Elements (AREA)

Claims (9)

1. Composition de nettoyage pour nettoyer des surfaces optiques, comprenant de 1 à 25% en poids d'un polymère particulaire qui est un polymère organique, un polymère polysiloxane ou un de leurs mélanges, dans laquelle le polymère a une granulomètrie comprise dans l'intervalle de 1 à 600 micromètres, et une dureté Rockwell comprise dans l'intervalle de R30 à M105, ou une dureté Shore comprise dans l'intervalle de A15 à D100, et un support comprenant de l'eau et un épaississant, lequel support est compatible avec les tissus oculaires et présente une viscosité suffisante pour maintenir en suspension le polymère particulaire.
2. Composition de nettoyage selon la revendication 1, dans laquelle l'épaississant est le polyéthylèneglycol, le Carbopol@, le cellulose, une hydroxyéthylcellulose ayant une masse moléculaire d'environ 15 000, ou un de leurs mélanges.
3. Composition de nettoyage selon la revendication 1 ou la revendication 2, dans laquelle le polymère particulaire a une dureté Rockwell comprise dans l'intervalle de R30 à M105.
4. Composition de nettoyage selon l'une quelconque des revendications précédentes, dans laquelle le polymère particulaire a une dureté Shore comprise dans l'intervalle de A15 à D100.
5. Composition de nettoyage selon l'une quelconque des revendications précédentes, dans laquelle le polymère particulaire est le polymère acétobutyrate de cellulose, polyéthylène, acrylonitrile-butadiène- styrène, acétal, poly(méthacrylate de méthyle), copolymère méthacrylate de méthyle/styrène, éthylcellulose, acétate de cellulose, acétobutyrate de cellulose, polychloro-trifluoréthylène, polyéthylène- tétrafluoréthylène modifié, Nylon 6@, Nylon 6/6@, Nylon 11@, Nylon 12@, polybutadiène, polyaryléther, polycarbonate, polyester PBT, polypropylène, polysulfone, polytétrafluoroéthylène, ionomère, polymère de fluoréthylène, silicone ou un de leurs mélanges.
6. Composition de nettoyage selon l'une quelconque des revendications précédentes, qui a une viscosité comprise dans l'intervalle de 150 à 1500 mPas.
7. Composition de nettoyage selon l'une quelconque des revendications précédentes, dans laquelle le polymère particulaire a une granulométrie comprise dans l'intervalle de 20 à 100 µm.
8. Composition de nettoyage selon l'une quelconque des revendications précédentes, dans laquelle on ajoute un tensioactif à la suspension.
9. Procédé pour le nettoyage de lentilles de contact, consistant à frotter la lentille de contact avec une composition de nettoyage selon l'une quelconque des revendications précédentes.
EP82301936A 1981-04-20 1982-04-15 Composition de nettoyage pour des surfaces optiques et procédé pour nettoyer une lentille de contact Expired EP0063472B1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT82301936T ATE32270T1 (de) 1981-04-20 1982-04-15 Reinigungszusammensetzung fuer optische oberflaechen und verfahren zur reinigung einer kontaktlinse.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25586181A 1981-04-20 1981-04-20
US255861 1981-04-20

Publications (3)

Publication Number Publication Date
EP0063472A2 EP0063472A2 (fr) 1982-10-27
EP0063472A3 EP0063472A3 (en) 1983-05-04
EP0063472B1 true EP0063472B1 (fr) 1988-01-27

Family

ID=22970167

Family Applications (1)

Application Number Title Priority Date Filing Date
EP82301936A Expired EP0063472B1 (fr) 1981-04-20 1982-04-15 Composition de nettoyage pour des surfaces optiques et procédé pour nettoyer une lentille de contact

Country Status (9)

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EP (1) EP0063472B1 (fr)
JP (1) JPS57192922A (fr)
AT (1) ATE32270T1 (fr)
AU (1) AU559965B2 (fr)
BR (1) BR8202239A (fr)
CA (2) CA1195127A (fr)
DE (1) DE3278049D1 (fr)
MX (1) MX166498B (fr)
ZA (1) ZA822496B (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4481126A (en) * 1982-07-26 1984-11-06 The Procter & Gamble Company No rinse liquid car cleaner with solid polymers
US4693840A (en) * 1982-07-26 1987-09-15 The Procter & Gamble Company No rinse liquid car cleaner with solid polymers
US4678698A (en) * 1983-04-12 1987-07-07 Minnesota Mining And Manufacturing Company Contact lens cleaning article
US4533399A (en) * 1983-04-12 1985-08-06 Minnesota Mining And Manufacturing Company Contact lens cleaning method
US4622258A (en) * 1983-04-12 1986-11-11 Minnesota Mining And Manufacturing Company Contact lens cleaning article
JPS60159721A (ja) * 1984-01-31 1985-08-21 Nippon Contact Lens Seizo Kk コンタクトレンズ用クリ−ナ−
US4655957A (en) * 1984-06-25 1987-04-07 Bausch & Lomb Incorporated Contact lens cleaning composition with polymeric beads
AT380897B (de) * 1984-12-10 1986-07-25 Koller Anton Mischung zur pflege und reinigung von kontaktlinsen
GB2188744B (en) * 1986-04-01 1989-11-15 Donald James Highgate Contact lens cleaners
JPH01501899A (ja) * 1986-12-24 1989-06-29 アルコン　ラボラトリーズ　インコーポレイテッド コンタクトレンズ用洗浄剤及びその使用方法
EP0292910B1 (fr) * 1987-05-28 1994-12-28 Colgate-Palmolive Company Composition de nettoyage pour surfaces dures
JPH01177014A (ja) * 1987-12-28 1989-07-13 Tome Sangyo Kk コンタクトレンズ用洗浄剤
WO1989012842A1 (fr) * 1988-06-18 1989-12-28 Tomei Sangyo Kabushiki Kaisha Detergent pour lentilles de contact et procede de lavage de lentilles de contact
US4855067A (en) * 1988-05-10 1989-08-08 Colgate-Palmolive Company Household cleaning composition
JPH01293314A (ja) * 1988-05-20 1989-11-27 Daicel Chem Ind Ltd コンタクトレンズ用洗浄剤
US4968447A (en) * 1988-08-11 1990-11-06 Gage Products Company Cleaning composition and method
JPH0633415B2 (ja) * 1988-12-02 1994-05-02 花王株式会社 皮膚洗浄剤組成物
US5128058A (en) * 1989-05-31 1992-07-07 Hoya Corporation Contact lens cleaner containing a microcapsular polishing agent
US5017238A (en) * 1989-08-30 1991-05-21 Dow Corning Corporation Aqueous cleaning dispersions using adsorptive polymeric powder and method of using
US5037485A (en) * 1989-09-14 1991-08-06 Dow Corning Corporation Method of cleaning surfaces
CA2039378A1 (fr) * 1990-04-03 1991-10-04 Toyoyasu Tanaka Dispositif de nettoyage des lentilles corneennes
DE19808054C2 (de) * 1998-02-26 2002-06-13 Boehme Chem Fab Kg Gegenstand zum Reinigen von Oberflächen
GB0004898D0 (en) 2000-03-02 2000-04-19 Ici Plc Extrusion process
CN1965066A (zh) * 2004-06-07 2007-05-16 宝洁公司 洗涤剂组合物
JP4896650B2 (ja) * 2006-09-29 2012-03-14 株式会社コーセー 新規な水溶性スクラブ剤及び該スクラブ剤を配合する油性皮膚洗浄料
DE102012222263A1 (de) * 2012-12-05 2014-06-05 Henkel Ag & Co. Kgaa Entfernung fettiger Anschmutzungen

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1295611A (fr) * 1970-07-16 1972-11-08
US3884826A (en) * 1973-07-20 1975-05-20 Barnes Hind Pharm Inc Thixotropic cleaning agent for hard contact lenses
US4048122A (en) * 1976-01-23 1977-09-13 Barnes-Hind Pharmaceuticals, Inc. Cleaning agents for contact lenses
CA1152843A (fr) * 1979-06-25 1983-08-30 Polymer Technology Corporation Nettoyant a teneur d'abrasifs pour verres d'optique

Also Published As

Publication number Publication date
MX166498B (es) 1993-01-12
AU8258782A (en) 1982-10-28
EP0063472A2 (fr) 1982-10-27
JPS632091B2 (fr) 1988-01-16
DE3278049D1 (en) 1988-03-03
JPS57192922A (en) 1982-11-27
ZA822496B (en) 1983-02-23
BR8202239A (pt) 1983-03-29
CA1270119B (fr) 1990-06-12
CA1195127A (fr) 1985-10-15
AU7372387A (en) 1987-10-08
ATE32270T1 (de) 1988-02-15
AU590848B2 (en) 1989-11-16
EP0063472A3 (en) 1983-05-04
AU559965B2 (en) 1987-03-26

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