EE9900187A - HIV proteaasi inhibiitorina kasulik 1-(3-aminoindasool-5-üül)-3-butüül-tsükliline uurea - Google Patents

HIV proteaasi inhibiitorina kasulik 1-(3-aminoindasool-5-üül)-3-butüül-tsükliline uurea

Info

Publication number
EE9900187A
EE9900187A EEP199900187A EE9900187A EE9900187A EE 9900187 A EE9900187 A EE 9900187A EE P199900187 A EEP199900187 A EE P199900187A EE 9900187 A EE9900187 A EE 9900187A EE 9900187 A EE9900187 A EE 9900187A
Authority
EE
Estonia
Prior art keywords
aminoindazol
butyl
protease inhibitor
hiv protease
cyclic urea
Prior art date
Application number
EEP199900187A
Other languages
English (en)
Estonian (et)
Inventor
David Rodgers James
Yuk-Sun Lam Patrick
Original Assignee
Dupont Pharmaceuticals Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dupont Pharmaceuticals Company filed Critical Dupont Pharmaceuticals Company
Publication of EE9900187A publication Critical patent/EE9900187A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • AIDS & HIV (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EEP199900187A 1996-11-08 1997-11-04 HIV proteaasi inhibiitorina kasulik 1-(3-aminoindasool-5-üül)-3-butüül-tsükliline uurea EE9900187A (et)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US74710396A 1996-11-08 1996-11-08
US2974696P 1996-11-08 1996-11-08
PCT/US1997/020036 WO1998020009A1 (en) 1996-11-08 1997-11-04 (4r,5s,6s,7r)-hexahydro-1- [5-(3-aminoinazole)methyl] -3-butyl-5,6-dihydroxy-4,7-bis [phaenylmethyl] -2h-1,3-diazepin-2-one, its preparation and its use as hiv protease inhibitor

Publications (1)

Publication Number Publication Date
EE9900187A true EE9900187A (et) 1999-12-15

Family

ID=26705295

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP199900187A EE9900187A (et) 1996-11-08 1997-11-04 HIV proteaasi inhibiitorina kasulik 1-(3-aminoindasool-5-üül)-3-butüül-tsükliline uurea

Country Status (19)

Country Link
EP (1) EP0937066A1 (xx)
JP (1) JP2001503429A (xx)
KR (1) KR20000053123A (xx)
CN (1) CN1235601A (xx)
AU (1) AU722489B2 (xx)
BR (1) BR9712755A (xx)
CA (1) CA2270963A1 (xx)
CZ (1) CZ157499A3 (xx)
EA (1) EA001154B1 (xx)
EE (1) EE9900187A (xx)
HU (1) HUP9904143A3 (xx)
IL (1) IL129726A0 (xx)
LV (1) LV12374B (xx)
NO (1) NO992229L (xx)
NZ (1) NZ335919A (xx)
PL (1) PL333412A1 (xx)
SI (1) SI9720071A (xx)
SK (1) SK59599A3 (xx)
WO (1) WO1998020009A1 (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0973767A1 (en) * 1997-03-31 2000-01-26 Dupont Pharmaceuticals Company Indazoles of cyclic ureas useful as hiv protease inhibitors
AU4716299A (en) * 1998-06-24 2000-01-10 Emory University Use of 3'-azido-2',3'-dideoxyuridine in combination with further anti-hiv drugs for the manufacture of a medicament for the treatment of hiv
FR2810039B1 (fr) 2000-06-13 2007-05-25 Centre Nat Rech Scient Composes urees cycliques et leur procede de preparation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5610294A (en) * 1991-10-11 1997-03-11 The Du Pont Merck Pharmaceutical Company Substituted cyclic carbonyls and derivatives thereof useful as retroviral protease inhibitors
DE69221309T2 (de) * 1991-10-11 1997-12-11 The Du Pont Merck Pharmaceutical Co., Wilmington, Del. Cyclische harnstoffe und analoga verwendbar als retrovirale proteasehemmer

Also Published As

Publication number Publication date
NO992229D0 (no) 1999-05-07
CN1235601A (zh) 1999-11-17
EA199900451A1 (ru) 1999-12-29
KR20000053123A (ko) 2000-08-25
SK59599A3 (en) 1999-12-10
WO1998020009A1 (en) 1998-05-14
NZ335919A (en) 2000-09-29
JP2001503429A (ja) 2001-03-13
IL129726A0 (en) 2000-02-29
AU5103398A (en) 1998-05-29
LV12374A (lv) 1999-11-20
CZ157499A3 (cs) 1999-11-17
PL333412A1 (en) 1999-12-06
LV12374B (en) 2000-04-20
EA001154B1 (ru) 2000-10-30
HUP9904143A3 (en) 2002-11-28
BR9712755A (pt) 1999-10-19
EP0937066A1 (en) 1999-08-25
NO992229L (no) 1999-06-07
SI9720071A (sl) 1999-12-31
AU722489B2 (en) 2000-08-03
CA2270963A1 (en) 1998-05-14
HUP9904143A2 (hu) 2000-06-28

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