EE9400071A - Pregnaanskeletiga steroidid, neid sisaldavad farmatseutilised kompositsioonid ja nende valmistamise protsess - Google Patents

Pregnaanskeletiga steroidid, neid sisaldavad farmatseutilised kompositsioonid ja nende valmistamise protsess

Info

Publication number
EE9400071A
EE9400071A EE9400071A EE9400071A EE9400071A EE 9400071 A EE9400071 A EE 9400071A EE 9400071 A EE9400071 A EE 9400071A EE 9400071 A EE9400071 A EE 9400071A EE 9400071 A EE9400071 A EE 9400071A
Authority
EE
Estonia
Prior art keywords
pregnant
steroids
skeletal
preparation
pharmaceutical compositions
Prior art date
Application number
EE9400071A
Other languages
English (en)
Estonian (et)
Inventor
Maho S�ndor
Tuba Zolt�n
Gere Anik
Vittay P�l
Kiss Bla
P�losi �va
Szporny L�zl�
Francsics Erzs�bet
Bo�r Anna
Balogh G�bor
G�r�g S�ndor
Original Assignee
Richter Gedeon Vegy�Szeti Gy�R Rt.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegy�Szeti Gy�R Rt. filed Critical Richter Gedeon Vegy�Szeti Gy�R Rt.
Publication of EE9400071A publication Critical patent/EE9400071A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/50Three nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
EE9400071A 1992-06-09 1994-06-29 Pregnaanskeletiga steroidid, neid sisaldavad farmatseutilised kompositsioonid ja nende valmistamise protsess EE9400071A (et)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU9201910A HU212308B (en) 1992-06-09 1992-06-09 Process for producing novel pregnane steroids and pharmaceutical compositions containing the same

Publications (1)

Publication Number Publication Date
EE9400071A true EE9400071A (et) 1995-12-15

Family

ID=10982020

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9400071A EE9400071A (et) 1992-06-09 1994-06-29 Pregnaanskeletiga steroidid, neid sisaldavad farmatseutilised kompositsioonid ja nende valmistamise protsess

Country Status (17)

Country Link
US (1) US5547949A (sv)
EP (1) EP0646126A1 (sv)
JP (1) JPH07507792A (sv)
KR (1) KR950701933A (sv)
AU (1) AU4352393A (sv)
CA (1) CA2136546A1 (sv)
CZ (1) CZ308094A3 (sv)
EE (1) EE9400071A (sv)
FI (1) FI945781A (sv)
HR (1) HRP930956A2 (sv)
HU (1) HU212308B (sv)
IL (1) IL105943A0 (sv)
NO (1) NO944749L (sv)
RU (1) RU94046369A (sv)
SI (1) SI9300311A (sv)
WO (1) WO1993025570A1 (sv)
ZA (1) ZA934036B (sv)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999061055A1 (en) 1998-05-22 1999-12-02 The Board Of Trustees Of The Leland Stanford Junior University Bifunctional molecules and therapies based thereon
US7081470B2 (en) * 2001-01-31 2006-07-25 H. Lundbeck A/S Use of GALR3 receptor antagonists for the treatment of depression and/or anxiety and compounds useful in such methods
US20040127502A1 (en) * 2001-01-31 2004-07-01 Synaptic Pharmaceutical Corporation Use of GAL3 antagonist for treatment of depression
MY141867A (en) * 2002-06-20 2010-07-16 Vertex Pharma Substituted pyrimidines useful as protein kinase inhibitors
WO2006116718A2 (en) 2005-04-28 2006-11-02 Proteus Biomedical, Inc. Pharma-informatics system
WO2007035716A2 (en) 2005-09-16 2007-03-29 Raptor Pharmaceutical Inc. Compositions comprising receptor-associated protein (rap) variants specific for cr-containing proteins and uses thereof
NL2000323C2 (nl) * 2005-12-20 2007-11-20 Pfizer Ltd Pyrimidine-derivaten.
ES2744879T3 (es) 2008-05-28 2020-02-26 Reveragen Biopharma Inc Moduladores esteroideos no hormonales de NF-kappaB para el tratamiento de enfermedades
ES2919563T3 (es) 2009-02-20 2022-07-27 Enhanx Biopharm Inc Sistema de administración de medicamentos a base de glutatión
EA024559B1 (ru) 2009-05-06 2016-09-30 Лаборэтори Скин Кэа, Инк. Композиции для нанесения на кератинизированную поверхность кожи млекопитающего и способ доставки
WO2011127048A2 (en) 2010-04-05 2011-10-13 Validus Biopharma NON-HORMONAL STEROID MODULATORS OF NF-ĸB FOR TREATMENT OF DISEASE
US10799514B2 (en) 2015-06-29 2020-10-13 Reveragen Biopharma, Inc. Non-hormonal steroid modulators of NF-kappa beta for treatment of disease
US11382922B2 (en) 2019-03-07 2022-07-12 Reveragen Biopharma, Inc. Aqueous oral pharmaceutical suspension compositions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5099019A (en) * 1985-09-12 1992-03-24 Upjohn Company Amines useful in producing pharmaceutically active CNS compounds
EP0263213B1 (en) * 1986-10-09 1995-09-06 The Upjohn Company C20 Through C26 amino steroids
FR2644787B1 (fr) * 1989-03-22 1995-02-03 Roussel Uclaf Nouveaux steroides 21 aminosubstitues, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant
FR2644789B1 (fr) * 1989-03-22 1995-02-03 Roussel Uclaf Nouveaux steroides 19-nor, 3-ceto comportant une chaine en 17 aminosubstituee, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant
CA2071000A1 (en) * 1990-01-26 1991-07-27 John M. Mccall 5-oxygenated-2,4,6-triaminopyrimidines

Also Published As

Publication number Publication date
NO944749D0 (no) 1994-12-08
FI945781A0 (sv) 1994-12-08
EP0646126A1 (en) 1995-04-05
HU9201910D0 (en) 1992-09-28
RU94046369A (ru) 1996-09-27
AU4352393A (en) 1994-01-04
JPH07507792A (ja) 1995-08-31
CA2136546A1 (en) 1993-12-23
NO944749L (no) 1995-02-08
CZ308094A3 (en) 1995-11-15
HU212308B (en) 1996-05-28
HRP930956A2 (hr) 1995-02-28
SI9300311A (sl) 1993-12-31
US5547949A (en) 1996-08-20
WO1993025570A1 (en) 1993-12-23
IL105943A0 (en) 1993-10-20
KR950701933A (ko) 1995-05-17
HUT64562A (en) 1994-01-28
FI945781A (sv) 1994-12-08
ZA934036B (en) 1994-01-06

Similar Documents

Publication Publication Date Title
IL84135A0 (en) 9-alpha-hydroxy steroids,process for their preparation,process for the preparation of the corresponding 9(11)-dehydro derivatives and pharmaceutical preparations containing said steroids
EE9500080A (et) Erütromütsiini derivaadid, nende valmistamismeetod ja neid sisaldav farmatseutiline kompositsioon
PT85329A (en) Process for the preparation of tetrahydronaphtaline and indane derivatives and of pharmaceutical compositions containing the same
EE9700333A (et) Substitueeritud 4-fenüülaminotiasoolid, nende valmistamise meetod ja neid sisaldavad farmakoloogilised kompositsioonid
CZ8895A3 (en) Derivatives of parathyroid hormone, process of their preparation and pharmaceutical compositions containing thereof
IL93423A0 (en) Piperidine compounds,their preparation and pharmaceutical compositions containing them
EE03110B1 (et) Steroidi estrid, nende valmistamise protsess ja neid sisaldavad ravimpreparaadid
IL116486A0 (en) Novel piperidine derivatives processes for their preparation and pharmaceutical compositions containing them
IL84021A0 (en) Piperidine compounds,their preparation and pharmaceutical compositions containing them
EE9400071A (et) Pregnaanskeletiga steroidid, neid sisaldavad farmatseutilised kompositsioonid ja nende valmistamise protsess
EP0470617A3 (en) 17-substituted corticoid-17-alkylcarbonates, a process for their preparation and pharmaceutical compositions containing them
EP0251453A3 (en) Substituted amino-dihydrooxazoles, -thiazoles and -imidazoles, process for their preparation and pharmaceutical compositions containing them
KR880700814A (ko) 아미노글리코사이드 스테로이드, 이의 제조방법, 이의 용도 및 이를 함유하는 약제학적 조성물
IL110157A (en) (1-Heteroazolyl-1-heterocyclyl) alkane derivatives a process for their preparation and pharmaceutical compositions containing them
HUT35478A (en) Pesticide compositions containing benzoyl-urea derivatives and process for producing benzoyl-urea derivatives and pharmaceutical compositions containing them
IL96366A0 (en) Steroids,their manufacture and pharmaceutical compositions containing them
IL107611A0 (en) Steroid compounds and pharmaceutical compositions containing them
EE9400148A (et) Tienotiasiini derivaadid, nende valmistamise meetod ja neid sisaldavad farmatseutilised preparaadid
HUT44527A (en) Process for producing new alkylene-diamine derivatives and pharmaceutical compositions containing them
FI951561A0 (sv) Nya 17 -substituerade 4-androstanderivat, farmaceutiska sammansättningar innehållande dessa samt förfarande för framställning av desamma
IL107994A0 (en) Steroids process for their preparation and pharmaceutical compositions containing them
ZA901753B (en) Steroid derivatives,pharmaceutical compositions containing them and process for preparing same
ZA901752B (en) Steroid diols,pharmaceutical compositions containing them and process for preparing same
IL84791A0 (en) Substituted aminopropionamides,process for their preparation and pharmaceutical compositions containing them
IL82332A (en) Substituted 2-phenylbenzothiazin(-3-)one derivatives,process for their preparation and pharmaceutical compositions containing them