EE04496B1 - Tetrahüdro-gamma-karboliinid, nende valmistamine ja kasutamine ravimina ning neid sisaldavad kompositsioonid - Google Patents
Tetrahüdro-gamma-karboliinid, nende valmistamine ja kasutamine ravimina ning neid sisaldavad kompositsioonidInfo
- Publication number
- EE04496B1 EE04496B1 EEP200000059A EEP200000059A EE04496B1 EE 04496 B1 EE04496 B1 EE 04496B1 EE P200000059 A EEP200000059 A EE P200000059A EE P200000059 A EEP200000059 A EE P200000059A EE 04496 B1 EE04496 B1 EE 04496B1
- Authority
- EE
- Estonia
- Prior art keywords
- optionally substituted
- preparation
- compositions containing
- carbolines
- medicaments
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Anesthesiology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP97202761A EP0905136A1 (en) | 1997-09-08 | 1997-09-08 | Tetrahydro gamma-carbolines |
PCT/EP1998/005710 WO1999012926A1 (en) | 1997-09-08 | 1998-09-01 | Tetrahydro gamma-carbolines |
Publications (2)
Publication Number | Publication Date |
---|---|
EE200000059A EE200000059A (et) | 2000-10-16 |
EE04496B1 true EE04496B1 (et) | 2005-06-15 |
Family
ID=8228715
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EEP200000059A EE04496B1 (et) | 1997-09-08 | 1998-09-01 | Tetrahüdro-gamma-karboliinid, nende valmistamine ja kasutamine ravimina ning neid sisaldavad kompositsioonid |
Country Status (28)
Country | Link |
---|---|
US (2) | US6303614B1 (ru) |
EP (2) | EP0905136A1 (ru) |
JP (1) | JP2001515899A (ru) |
KR (1) | KR100603896B1 (ru) |
CN (1) | CN1110496C (ru) |
AT (1) | ATE243209T1 (ru) |
AU (1) | AU752410B2 (ru) |
BR (1) | BR9811769A (ru) |
CA (1) | CA2301807A1 (ru) |
CZ (1) | CZ297220B6 (ru) |
DE (1) | DE69815700T2 (ru) |
EE (1) | EE04496B1 (ru) |
ES (1) | ES2202902T3 (ru) |
HK (1) | HK1029107A1 (ru) |
HR (1) | HRP20000108A2 (ru) |
HU (1) | HUP0003577A3 (ru) |
ID (1) | ID23954A (ru) |
IL (1) | IL134894A (ru) |
MY (1) | MY129176A (ru) |
NO (1) | NO315236B1 (ru) |
NZ (1) | NZ503096A (ru) |
PL (1) | PL191863B1 (ru) |
RU (1) | RU2208614C2 (ru) |
SK (1) | SK285594B6 (ru) |
TR (1) | TR200000616T2 (ru) |
TW (1) | TW531539B (ru) |
WO (1) | WO1999012926A1 (ru) |
ZA (1) | ZA988161B (ru) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1944306A1 (en) * | 2003-09-17 | 2008-07-16 | Janssen Pharmaceutica, N.V. | Fused heterocyclic compounds as serotonin receptor modulators |
CN1882590B (zh) * | 2003-09-17 | 2014-03-05 | 詹森药业有限公司 | 作为血清素受体调节剂的稠合杂环化合物 |
CN103788089A (zh) * | 2003-09-17 | 2014-05-14 | 詹森药业有限公司 | 作为血清素受体调节剂的稠合杂环化合物 |
EP1757605A4 (en) * | 2004-04-12 | 2007-12-19 | Taisho Pharmaceutical Co Ltd | CYCLIC AMINE COMPOUND |
EP1856126A2 (en) | 2005-02-17 | 2007-11-21 | Wyeth a Corporation of the State of Delaware | Cycloalkylfused indole, benzothiophene, benzofuran and indene derivatives |
FR2885905A1 (fr) * | 2005-05-23 | 2006-11-24 | Trophos Sa | Nouveaux composes chimiques et leurs utilisations comme medicament |
WO2007009485A1 (en) * | 2005-07-22 | 2007-01-25 | Pharma C S.A. | Substituted 8-phenoxy-y-carboline derivatives with 5ht1 activity |
WO2007058580A1 (en) * | 2005-11-15 | 2007-05-24 | Astrazeneca Ab | Novel 2-aminopyrimidinone derivatives and their use |
US7637410B2 (en) * | 2006-10-06 | 2009-12-29 | Tyco Healthcare Group Lp | Surgical instrument including a locking assembly |
MX2010003149A (es) * | 2007-09-20 | 2010-11-10 | D2E Llc | Derivados que contienen fluor de pirido[4,3-b]indoles hidrogenados con propiedades neuroprotectoras y de mejoramiento de cognicion, proceso de preparacion y uso. |
WO2009082268A2 (ru) | 2007-12-21 | 2009-07-02 | Alla Chem, Llc | ЛИГАНДЫ α-АДРЕНОЦЕПТОРОВ, ДОПАМИНОВЫХ, ГИСТАМИНОВЫХ, ИМИДАЗОЛИНОВЫХ И СЕРОТОНИНОВЫХ РЕЦЕПТОРОВ И ИХ ПРИМЕНЕНИЕ |
RU2374245C1 (ru) | 2008-08-22 | 2009-11-27 | Андрей Александрович Иващенко | Лиганд с широким спектром одновременной рецепторной активности, фармацевтическая композиция, способ ее получения и лекарственное средство |
CN105399674B (zh) | 2015-12-31 | 2017-02-15 | 青岛清原化合物有限公司 | 吡唑类化合物或其盐、制备方法、除草剂组合物及用途 |
CN106631941B (zh) * | 2016-12-30 | 2018-09-28 | 青岛瀚生生物科技股份有限公司 | 一种2-甲基-3氯苯基甲硫醚的制备方法 |
GB201704325D0 (en) * | 2017-03-17 | 2017-05-03 | Argonaut Therapeutics Ltd | Compounds |
CN110698474B (zh) * | 2019-11-14 | 2021-11-02 | 福州大学 | 一种α位取代四氢-γ-咔啉类化合物及其制备方法和应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3410286C2 (de) * | 1984-03-21 | 1986-01-23 | Fresenius AG, 6380 Bad Homburg | Verfahren zur Trennung von Blut sowie Vorrichtung zur Durchführung des Verfahrens |
US4672117A (en) * | 1985-09-16 | 1987-06-09 | American Home Products Corporation | Antipsychotic gamma-carbolines |
US4798896A (en) * | 1988-01-19 | 1989-01-17 | American Home Products Corporation | Antipsychotic gamma-carboline N-oxides |
EP0705832B1 (en) * | 1994-09-12 | 2003-08-13 | Eli Lilly And Company Limited | Serotonergic modulators |
-
1997
- 1997-09-08 EP EP97202761A patent/EP0905136A1/en not_active Withdrawn
-
1998
- 1998-09-01 CZ CZ20000726A patent/CZ297220B6/cs not_active IP Right Cessation
- 1998-09-01 TR TR2000/00616T patent/TR200000616T2/xx unknown
- 1998-09-01 CA CA002301807A patent/CA2301807A1/en not_active Abandoned
- 1998-09-01 WO PCT/EP1998/005710 patent/WO1999012926A1/en active IP Right Grant
- 1998-09-01 EE EEP200000059A patent/EE04496B1/xx not_active IP Right Cessation
- 1998-09-01 AU AU97421/98A patent/AU752410B2/en not_active Ceased
- 1998-09-01 RU RU2000109310/04A patent/RU2208614C2/ru not_active IP Right Cessation
- 1998-09-01 JP JP2000510733A patent/JP2001515899A/ja not_active Withdrawn
- 1998-09-01 ES ES98951365T patent/ES2202902T3/es not_active Expired - Lifetime
- 1998-09-01 CN CN98808818A patent/CN1110496C/zh not_active Expired - Fee Related
- 1998-09-01 KR KR1020007000970A patent/KR100603896B1/ko not_active IP Right Cessation
- 1998-09-01 PL PL339143A patent/PL191863B1/pl not_active IP Right Cessation
- 1998-09-01 BR BR9811769-6A patent/BR9811769A/pt not_active Application Discontinuation
- 1998-09-01 US US09/508,240 patent/US6303614B1/en not_active Expired - Fee Related
- 1998-09-01 DE DE69815700T patent/DE69815700T2/de not_active Expired - Fee Related
- 1998-09-01 EP EP98951365A patent/EP1015451B1/en not_active Expired - Lifetime
- 1998-09-01 NZ NZ503096A patent/NZ503096A/en unknown
- 1998-09-01 AT AT98951365T patent/ATE243209T1/de not_active IP Right Cessation
- 1998-09-01 IL IL13489498A patent/IL134894A/xx not_active IP Right Cessation
- 1998-09-01 SK SK299-2000A patent/SK285594B6/sk unknown
- 1998-09-01 ID IDW20000432A patent/ID23954A/id unknown
- 1998-09-02 TW TW087114508A patent/TW531539B/zh not_active IP Right Cessation
- 1998-09-07 ZA ZA9808161A patent/ZA988161B/xx unknown
- 1998-09-07 MY MYPI98004080A patent/MY129176A/en unknown
- 1998-09-08 HU HU0003577A patent/HUP0003577A3/hu unknown
-
2000
- 2000-02-14 NO NO20000737A patent/NO315236B1/no unknown
- 2000-02-29 HR HR20000108A patent/HRP20000108A2/xx not_active Application Discontinuation
- 2000-11-10 HK HK00107165A patent/HK1029107A1/xx not_active IP Right Cessation
-
2001
- 2001-08-15 US US09/930,005 patent/US6506768B2/en not_active Expired - Fee Related
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB4A | Valid patent at the end of a year |
Effective date: 20051231 |
|
KB4A | Valid patent at the end of a year |
Effective date: 20061231 |
|
KB4A | Valid patent at the end of a year |
Effective date: 20071231 |
|
MM4A | Lapsed by not paying the annual fees |
Effective date: 20070901 |