EE04093B1 - HIV proteaasi inhibiitorit VX 478 ja vees lahustuva vitamiin E derivaati vitamiin E-TPGSi sisaldavad preparaadid - Google Patents

HIV proteaasi inhibiitorit VX 478 ja vees lahustuva vitamiin E derivaati vitamiin E-TPGSi sisaldavad preparaadid

Info

Publication number
EE04093B1
EE04093B1 EE9800323A EE9800323A EE04093B1 EE 04093 B1 EE04093 B1 EE 04093B1 EE 9800323 A EE9800323 A EE 9800323A EE 9800323 A EE9800323 A EE 9800323A EE 04093 B1 EE04093 B1 EE 04093B1
Authority
EE
Estonia
Prior art keywords
vitamin
tpgs
water
protease inhibitor
hiv protease
Prior art date
Application number
EE9800323A
Other languages
English (en)
Other versions
EE9800323A (et
Inventor
Gary Tillman Lloyd
K. Roy Arup
Original Assignee
Glaxo Group Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9606372.2A external-priority patent/GB9606372D0/en
Priority claimed from US08/820,848 external-priority patent/US6730679B1/en
Application filed by Glaxo Group Limited filed Critical Glaxo Group Limited
Priority claimed from PCT/EP1997/001438 external-priority patent/WO1997035587A1/en
Publication of EE9800323A publication Critical patent/EE9800323A/et
Publication of EE04093B1 publication Critical patent/EE04093B1/et

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
EE9800323A 1996-03-22 1997-03-21 HIV proteaasi inhibiitorit VX 478 ja vees lahustuva vitamiin E derivaati vitamiin E-TPGSi sisaldavad preparaadid EE04093B1 (et)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US1389396P 1996-03-22 1996-03-22
GBGB9606372.2A GB9606372D0 (en) 1996-03-26 1996-03-26 Pharmaceutical formulations
US08/820,848 US6730679B1 (en) 1996-03-22 1997-03-20 Pharmaceutical formulations
PCT/EP1997/001438 WO1997035587A1 (en) 1996-03-22 1997-03-21 Compositions comprising an hiv protease inhibitor such as vx 478 and a water soluble vitamin e compound such as vitamin e-tpgs

Publications (2)

Publication Number Publication Date
EE9800323A EE9800323A (et) 1999-04-15
EE04093B1 true EE04093B1 (et) 2003-08-15

Family

ID=27268205

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9800323A EE04093B1 (et) 1996-03-22 1997-03-21 HIV proteaasi inhibiitorit VX 478 ja vees lahustuva vitamiin E derivaati vitamiin E-TPGSi sisaldavad preparaadid

Country Status (24)

Country Link
EP (1) EP0906107B1 (et)
CN (1) CN1225587A (et)
AP (1) AP1150A (et)
AT (1) ATE230602T1 (et)
AU (1) AU724239B2 (et)
BR (1) BR9708238A (et)
CA (1) CA2249336C (et)
CY (1) CY2444B1 (et)
CZ (1) CZ289958B6 (et)
DE (1) DE69718315T2 (et)
DK (1) DK0906107T3 (et)
EA (1) EA001484B1 (et)
EE (1) EE04093B1 (et)
ES (1) ES2190528T3 (et)
GE (1) GEP20012464B (et)
HK (1) HK1016896A1 (et)
IS (1) IS2066B (et)
NO (1) NO317639B1 (et)
NZ (1) NZ331645A (et)
RO (1) RO119923B1 (et)
SI (1) SI0906107T1 (et)
SK (1) SK284244B6 (et)
TR (1) TR199801881T2 (et)
UY (1) UY25926A1 (et)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114366808B (zh) * 2021-12-14 2023-10-13 南京农业大学 一种多糖和病毒抗原共递送纳米疫苗、其制备方法及应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IS2334B (is) * 1992-09-08 2008-02-15 Vertex Pharmaceuticals Inc., (A Massachusetts Corporation) Aspartyl próteasi hemjari af nýjum flokki súlfonamíða
GB9409778D0 (en) * 1994-05-16 1994-07-06 Dumex Ltd As Compositions
EP0825849A1 (en) * 1995-05-19 1998-03-04 Abbott Laboratories Self-emulsifying formulations of lipophilic drugs

Also Published As

Publication number Publication date
EA199800755A1 (ru) 1999-06-24
SK126998A3 (en) 1999-10-08
CZ289958B6 (cs) 2002-05-15
RO119923B1 (ro) 2005-06-30
SK284244B6 (sk) 2004-12-01
CN1225587A (zh) 1999-08-11
DE69718315T2 (de) 2003-10-30
DK0906107T3 (da) 2003-05-05
EP0906107B1 (en) 2003-01-08
TR199801881T2 (xx) 1999-01-18
CA2249336A1 (en) 1997-10-02
ATE230602T1 (de) 2003-01-15
NZ331645A (en) 2000-02-28
NO984386L (no) 1998-11-20
IS4840A (is) 1998-08-28
EE9800323A (et) 1999-04-15
IS2066B (is) 2005-11-15
CZ303598A3 (cs) 1999-03-17
DE69718315D1 (de) 2003-02-13
AU724239B2 (en) 2000-09-14
NO984386D0 (no) 1998-09-21
CA2249336C (en) 2005-11-22
SI0906107T1 (en) 2003-08-31
GEP20012464B (en) 2001-06-25
BR9708238A (pt) 1999-08-03
CY2444B1 (en) 2004-11-12
HK1016896A1 (en) 1999-11-12
AP1150A (en) 2003-03-14
AP9801343A0 (en) 1998-09-30
AU2159197A (en) 1997-10-17
EA001484B1 (ru) 2001-04-23
NO317639B1 (no) 2004-11-29
UY25926A1 (es) 2000-09-29
ES2190528T3 (es) 2003-08-01
EP0906107A1 (en) 1999-04-07

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Legal Events

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KB4A Valid patent at the end of a year

Effective date: 20031231

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