EE04054B1 - Tetrasoolderivaadid, nende kasutamine ravimite valmistamiseks ja neid sisaldav ravim - Google Patents

Tetrasoolderivaadid, nende kasutamine ravimite valmistamiseks ja neid sisaldav ravim

Info

Publication number
EE04054B1
EE04054B1 EEP200000033A EEP200000033A EE04054B1 EE 04054 B1 EE04054 B1 EE 04054B1 EE P200000033 A EEP200000033 A EE P200000033A EE P200000033 A EEP200000033 A EE P200000033A EE 04054 B1 EE04054 B1 EE 04054B1
Authority
EE
Estonia
Prior art keywords
medicaments
manufacture
tetrazole derivatives
medicaments containing
tetrazole
Prior art date
Application number
EEP200000033A
Other languages
English (en)
Estonian (et)
Inventor
Amschler Hermann
Flockerzi Dieter
Ulrich Wolf-R�diger
B�r Thomas
Martin Thomas
Schudt Christian
Hatzelmann Armin
Beume Rolf
H�fner Dietrich
Boss Hildegard
Kley Hans-Peter
Gutterer Beate
Original Assignee
Byk Gulden Lomberg Chemische Fabrik Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chemische Fabrik Gmbh filed Critical Byk Gulden Lomberg Chemische Fabrik Gmbh
Publication of EE200000033A publication Critical patent/EE200000033A/xx
Publication of EE04054B1 publication Critical patent/EE04054B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Otolaryngology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
EEP200000033A 1997-07-25 1998-07-18 Tetrasoolderivaadid, nende kasutamine ravimite valmistamiseks ja neid sisaldav ravim EE04054B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97112792 1997-07-25
PCT/EP1998/004477 WO1999005111A1 (en) 1997-07-25 1998-07-18 Novel tetrazole derivatives

Publications (2)

Publication Number Publication Date
EE200000033A EE200000033A (et) 2000-10-16
EE04054B1 true EE04054B1 (et) 2003-06-16

Family

ID=8227116

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200000033A EE04054B1 (et) 1997-07-25 1998-07-18 Tetrasoolderivaadid, nende kasutamine ravimite valmistamiseks ja neid sisaldav ravim

Country Status (17)

Country Link
US (1) US6410551B1 (de)
EP (1) EP0998460B1 (de)
JP (1) JP2001510825A (de)
AT (1) ATE260899T1 (de)
AU (1) AU753615B2 (de)
CA (1) CA2297923A1 (de)
CZ (1) CZ293725B6 (de)
DE (1) DE69822162T2 (de)
DK (1) DK0998460T3 (de)
EE (1) EE04054B1 (de)
ES (1) ES2217575T3 (de)
HU (1) HUP0002510A3 (de)
IL (1) IL133824A (de)
PL (1) PL190685B1 (de)
PT (1) PT998460E (de)
SI (1) SI0998460T1 (de)
WO (1) WO1999005111A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA003780B1 (ru) * 1999-01-15 2003-08-28 Алтана Фарма Аг Фенилфенантридины с ингибирующей фдэ-4 активностью
CA2359404A1 (en) 1999-01-15 2000-07-20 Beate Gutterer Phenanthridine-n-oxides with pde-iv inhibiting activity
JP2002534507A (ja) 1999-01-15 2002-10-15 ビイク グルデン ロンベルク ヒエーミツシエ フアブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング 新規６−アリールフェナントリジン
AU2904300A (en) 1999-01-15 2000-08-01 Byk Gulden Lomberg Chemische Fabrik Gmbh Polysubstituted 6-phenylphenanthridines with pde-iv inhibiting activity
DE60019894T2 (de) * 1999-01-15 2006-01-12 Altana Pharma Ag Phenantrhridin-n-oxides mit pde-iv hemmender wirkung
SK287231B6 (sk) 1999-08-21 2010-04-07 Nycomed Gmbh Liečivo zahŕňajúce PDE inhibítor a agonistu beta2 adrenoreceptora
DE60133879D1 (de) 2000-01-11 2008-06-19 Nycomed Gmbh Phenanthridin -n- oxide
SI1303506T1 (en) 2000-07-14 2005-06-30 Altana Pharma Ag 6-heteroarylphenanthridines
AU2001281965A1 (en) * 2000-07-14 2002-01-30 Byk Gulden Lomberg Chemische Fabrik G.M.B.H. Novel 6-phenylphenanthridines
AU2001267589A1 (en) * 2000-07-14 2002-01-30 Byk Gulden Lomberg Chemische Fabrik G.M.B.H. Cycloalkyl - or cycloalkylmethyl-substituted 6-phenylphenanthridines
WO2002006239A1 (en) * 2000-07-14 2002-01-24 Altana Pharma Ag Phenanthridine n-oxides
JP2005537312A (ja) * 2002-08-17 2005-12-08 アルタナ　ファルマ　アクチエンゲゼルシャフト 新規のフェナントリジン
US7423046B2 (en) * 2002-08-29 2008-09-09 Nycomed Gmbh 3-hydroxy-6-phenylphenanthridines as pde-4 inhibitors
US7329676B2 (en) 2002-08-29 2008-02-12 Nycomed Gmbh 2-hydroxy-6-phenylphenanthridines as PDE-4 inhibitors
RU2282615C2 (ru) * 2002-11-20 2006-08-27 Пфайзер Продактс Инк. Способ получения индан-1,3-дикарбоновой кислоты
AU2004226353A1 (en) 2003-04-01 2004-10-14 Laboratoires Serono Sa Inhibitors of phosphodiesterases in infertility
US20060189641A1 (en) * 2003-07-31 2006-08-24 Beate Schmidt Novel 6-phenlyphenanthridines
US20060189645A1 (en) * 2003-07-31 2006-08-24 Altana Pharma Ag Novel 6-phenylphenantridines
JP4728259B2 (ja) * 2004-02-18 2011-07-20 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 効果的なホスホジエステラーゼ（ｐｄｅ）４インヒビターとしての新規のグアニジニル置換されたヒドロキシ−６−フェニルフェナントリジン
AR049419A1 (es) * 2004-03-03 2006-08-02 Altana Pharma Ag Hidroxi-6-fenilfenantridinas sustituidas con heterociclilo
RS52916B (sr) 2004-03-03 2014-02-28 Takeda Gmbh Novi hidroksi-6-heteroarilfenantridini i njihova primena kao pde4 inhibitori
AU2005220034A1 (en) * 2004-03-09 2005-09-15 Nycomed Gmbh Novel isoamido-substituted hydroxy-6-phenylphenanthridines and their use as PDE4 inhibitors
EP1725532A1 (de) * 2004-03-10 2006-11-29 Altana Pharma AG Neue difluorethoxysubstituierte hydroxy-6-phenylphenanthridine und deren verwendung als pde4-inhibitoren
AU2005221831A1 (en) * 2004-03-10 2005-09-22 Nycomed Gmbh Novel thio-containing hydroxy-6-phenylphenanthridines and their use as PDE4 inhibitors
EP1725534A1 (de) * 2004-03-10 2006-11-29 Altana Pharma AG Neue amidosubstituierte hydroxy-6-phenylphenanthridine und deren verwendung als pde4-inhibitoren
SI1856093T1 (sl) 2005-03-02 2010-03-31 Nycomed Gmbh Hidrokloridna sol R aR bR dimetoksipiridin il etoksi metoksi a b heksahidrofenantridin ola
ES2460897T3 (es) 2007-10-04 2014-05-14 F. Hoffmann-La Roche Ag Derivados de ciclopropil aril amida y usos de los mismos

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9027055D0 (en) 1990-12-13 1991-02-06 Sandoz Ltd Organic compounds
JP4138003B2 (ja) * 1996-01-31 2008-08-20 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規のフェナントリジン
ES2184077T3 (es) * 1996-03-26 2003-04-01 Altana Pharma Ag Nuevas fenantridinas sustituidas en la posicion 6.

Also Published As

Publication number Publication date
PT998460E (pt) 2004-07-30
DE69822162T2 (de) 2005-01-27
IL133824A (en) 2005-12-18
CZ293725B6 (cs) 2004-07-14
CA2297923A1 (en) 1999-02-04
HUP0002510A3 (en) 2002-10-28
AU8977098A (en) 1999-02-16
US6410551B1 (en) 2002-06-25
HUP0002510A2 (hu) 2000-12-28
ATE260899T1 (de) 2004-03-15
DE69822162D1 (de) 2004-04-08
PL190685B1 (pl) 2005-12-30
PL338339A1 (en) 2000-10-23
CZ2000282A3 (cs) 2000-08-16
SI0998460T1 (en) 2004-08-31
IL133824A0 (en) 2001-04-30
EP0998460B1 (de) 2004-03-03
WO1999005111A1 (en) 1999-02-04
DK0998460T3 (da) 2004-07-05
EP0998460A1 (de) 2000-05-10
EE200000033A (et) 2000-10-16
JP2001510825A (ja) 2001-08-07
AU753615B2 (en) 2002-10-24
ES2217575T3 (es) 2004-11-01

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Legal Events

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KB4A Valid patent at the end of a year

Effective date: 20031231

KB4A Valid patent at the end of a year

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KB4A Valid patent at the end of a year

Effective date: 20051231

KB4A Valid patent at the end of a year

Effective date: 20061231

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KB4A Valid patent at the end of a year

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Effective date: 20091231

MM4A Lapsed by not paying the annual fees

Effective date: 20090718