EE04054B1 - Tetrasoolderivaadid, nende kasutamine ravimite valmistamiseks ja neid sisaldav ravim - Google Patents

Tetrasoolderivaadid, nende kasutamine ravimite valmistamiseks ja neid sisaldav ravim

Info

Publication number
EE04054B1
EE04054B1 EEP200000033A EEP200000033A EE04054B1 EE 04054 B1 EE04054 B1 EE 04054B1 EE P200000033 A EEP200000033 A EE P200000033A EE P200000033 A EEP200000033 A EE P200000033A EE 04054 B1 EE04054 B1 EE 04054B1
Authority
EE
Estonia
Prior art keywords
medicaments
manufacture
tetrazole derivatives
medicaments containing
tetrazole
Prior art date
Application number
EEP200000033A
Other languages
English (en)
Estonian (et)
Inventor
Amschler Hermann
Flockerzi Dieter
Ulrich Wolf-R�diger
B�r Thomas
Martin Thomas
Schudt Christian
Hatzelmann Armin
Beume Rolf
H�fner Dietrich
Boss Hildegard
Kley Hans-Peter
Gutterer Beate
Original Assignee
Byk Gulden Lomberg Chemische Fabrik Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chemische Fabrik Gmbh filed Critical Byk Gulden Lomberg Chemische Fabrik Gmbh
Publication of EE200000033A publication Critical patent/EE200000033A/xx
Publication of EE04054B1 publication Critical patent/EE04054B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
EEP200000033A 1997-07-25 1998-07-18 Tetrasoolderivaadid, nende kasutamine ravimite valmistamiseks ja neid sisaldav ravim EE04054B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97112792 1997-07-25
PCT/EP1998/004477 WO1999005111A1 (en) 1997-07-25 1998-07-18 Novel tetrazole derivatives

Publications (2)

Publication Number Publication Date
EE200000033A EE200000033A (et) 2000-10-16
EE04054B1 true EE04054B1 (et) 2003-06-16

Family

ID=8227116

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200000033A EE04054B1 (et) 1997-07-25 1998-07-18 Tetrasoolderivaadid, nende kasutamine ravimite valmistamiseks ja neid sisaldav ravim

Country Status (17)

Country Link
US (1) US6410551B1 (cs)
EP (1) EP0998460B1 (cs)
JP (1) JP2001510825A (cs)
AT (1) ATE260899T1 (cs)
AU (1) AU753615B2 (cs)
CA (1) CA2297923A1 (cs)
CZ (1) CZ293725B6 (cs)
DE (1) DE69822162T2 (cs)
DK (1) DK0998460T3 (cs)
EE (1) EE04054B1 (cs)
ES (1) ES2217575T3 (cs)
HU (1) HUP0002510A3 (cs)
IL (1) IL133824A (cs)
PL (1) PL190685B1 (cs)
PT (1) PT998460E (cs)
SI (1) SI0998460T1 (cs)
WO (1) WO1999005111A1 (cs)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2241571T3 (es) * 1999-01-15 2005-11-01 Altana Pharma Ag N-oxidos de fenantrinida con actividad inhividora de pde-iv.
WO2000042017A1 (en) 1999-01-15 2000-07-20 Byk Gulden Lomberg Chemische Fabrik Gmbh Phenanthridine-n-oxides with pde-iv inhibiting activity
PT1147088E (pt) 1999-01-15 2006-05-31 Altana Pharma Ag 6-arilfenantridinas com actividade inibitoria da pde-iv
ES2254132T3 (es) * 1999-01-15 2006-06-16 Altana Pharma Ag Fenilfenantridinas con actividad inhibidora de pde-iv.
JP2002534506A (ja) 1999-01-15 2002-10-15 ビイク グルデン ロンベルク ヒエーミツシエ フアブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング Ｐｄｅ−ｉｖ抑制作用を有する多重に置換された６−フェニルフェナントリジン
NZ517166A (en) 1999-08-21 2004-01-30 Altana Pharma Ag Synergistic combination of PDE inhibitors and beta 2 adrenoceptor agonists
AU782908B2 (en) 2000-01-11 2005-09-08 Altana Pharma Ag Phenanthridine-N-oxides
AU2001269126A1 (en) * 2000-07-14 2002-01-30 Byk Gulden Lomberg Chemische Fabrik G.M.B.H. Phenanthridine n-oxides
WO2002005616A1 (en) * 2000-07-14 2002-01-24 Altana Pharma Ag Novel 6-phenylphenanthridines
AU2001267589A1 (en) * 2000-07-14 2002-01-30 Byk Gulden Lomberg Chemische Fabrik G.M.B.H. Cycloalkyl - or cycloalkylmethyl-substituted 6-phenylphenanthridines
DK1303506T3 (da) 2000-07-14 2005-05-30 Altana Pharma Ag 6-heteroarylphenanthridiner
US20060116518A1 (en) * 2002-08-17 2006-06-01 Altana Pharma Ag Novel phenanthridines
ATE353217T1 (de) * 2002-08-29 2007-02-15 Altana Pharma Ag 3-hydroxy-6-phenylphenanthridine als pde-4 inhibitoren
CA2495827C (en) * 2002-08-29 2012-05-08 Altana Pharma Ag 2-hydroxy-6-phenylphenanthridines as pde-4 inhibitors
EP1565421B1 (en) * 2002-11-20 2008-07-23 Pfizer Products Inc. A method for preparing indan-1,3-dicarboxylic acid
EP1624893A2 (en) 2003-04-01 2006-02-15 Applied Research Systems ARS Holding N.V. Inhibitors of phosphodiesterases in infertility
EP1658270A1 (en) * 2003-07-31 2006-05-24 ALTANA Pharma AG Novel 6-phenylphenantridines
WO2005012253A1 (en) * 2003-07-31 2005-02-10 Altana Pharma Ag Novel 6-phenylphenanthridines
JP4728259B2 (ja) * 2004-02-18 2011-07-20 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 効果的なホスホジエステラーゼ（ｐｄｅ）４インヒビターとしての新規のグアニジニル置換されたヒドロキシ−６−フェニルフェナントリジン
AR049419A1 (es) * 2004-03-03 2006-08-02 Altana Pharma Ag Hidroxi-6-fenilfenantridinas sustituidas con heterociclilo
PT2589599E (pt) 2004-03-03 2014-09-02 Takeda Gmbh Novas hidroxi-6-heteroarilfenantridinas e sua utilização como inibidores de pde4
KR20060124784A (ko) * 2004-03-09 2006-12-05 알타나 파마 아게 신규한 이소아미도 치환된 히드록시-6-페닐페난트리딘 및ｐｄｅ４ 억제제로서의 이의 용도
EP1725533A1 (en) * 2004-03-10 2006-11-29 Altana Pharma AG Novel thio containing hydroxy-6-phenylphenanthridines and their use as pde4 inhibitors
BRPI0508471A8 (pt) * 2004-03-10 2019-01-15 Altana Pharma Ag compostos de hidróxi-6-fenilfenantidinas substituídas por difluoroetóxi, composição farmacêutica e uso para a produção dos mesmos
NZ549254A (en) * 2004-03-10 2010-06-25 Nycomed Gmbh Amido-substituted hydroxy-6-phenylphenanthridines and their use as PDE4 inhibitors
EA015376B1 (ru) 2005-03-02 2011-08-30 Никомед Гмбх СОЛИ ПРОИЗВОДНЫХ 6-ГЕТЕРОАРИЛ-(1,2,3,4,4a,10b)-ГЕКСАГИДРОФЕНАНТРИДИНА И ИХ ПРИМЕНЕНИЕ
CA2699625C (en) 2007-10-04 2016-02-02 F. Hoffmann-La Roche Ag Cyclopropyl aryl amide derivatives and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9027055D0 (en) 1990-12-13 1991-02-06 Sandoz Ltd Organic compounds
WO1997028131A1 (de) * 1996-01-31 1997-08-07 Byk Gulden Lomberg Chemische Fabrik Gmbh Neue phenanthridine
PT889886E (pt) * 1996-03-26 2003-02-28 Altana Pharma Ag Novas fenantridinas substituidas na posicao 6

Also Published As

Publication number Publication date
EP0998460A1 (en) 2000-05-10
CZ2000282A3 (cs) 2000-08-16
PL338339A1 (en) 2000-10-23
PL190685B1 (pl) 2005-12-30
DE69822162T2 (de) 2005-01-27
PT998460E (pt) 2004-07-30
HUP0002510A3 (en) 2002-10-28
HUP0002510A2 (hu) 2000-12-28
EP0998460B1 (en) 2004-03-03
ATE260899T1 (de) 2004-03-15
IL133824A0 (en) 2001-04-30
US6410551B1 (en) 2002-06-25
ES2217575T3 (es) 2004-11-01
DE69822162D1 (de) 2004-04-08
CZ293725B6 (cs) 2004-07-14
WO1999005111A1 (en) 1999-02-04
CA2297923A1 (en) 1999-02-04
EE200000033A (et) 2000-10-16
DK0998460T3 (da) 2004-07-05
AU753615B2 (en) 2002-10-24
SI0998460T1 (en) 2004-08-31
AU8977098A (en) 1999-02-16
IL133824A (en) 2005-12-18
JP2001510825A (ja) 2001-08-07

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