EE01561U1 - Meetod vedelas proovis vähemalt ühe orgaanilise analüüdi tuvastamiseks ja kvantifitseerimiseks. - Google Patents

Meetod vedelas proovis vähemalt ühe orgaanilise analüüdi tuvastamiseks ja kvantifitseerimiseks.

Info

Publication number
EE01561U1
EE01561U1 EEU201900011U EEU201900011U EE01561U1 EE 01561 U1 EE01561 U1 EE 01561U1 EE U201900011 U EEU201900011 U EE U201900011U EE U201900011 U EEU201900011 U EE U201900011U EE 01561 U1 EE01561 U1 EE 01561U1
Authority
EE
Estonia
Prior art keywords
detection
analyte
quantification
organic
liquid sample
Prior art date
Application number
EEU201900011U
Other languages
English (en)
Inventor
Sergei BABITSHENKO
Jaak Järv
Aleksei Kuznetsov
Anton MASTITSKI
Original Assignee
Qanikdx Oü
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Qanikdx Oü filed Critical Qanikdx Oü
Priority to EEU201900011U priority Critical patent/EE01561U1/et
Priority to EP20703391.1A priority patent/EP3924734A1/en
Priority to US17/251,536 priority patent/US11650205B2/en
Priority to EA202192229A priority patent/EA202192229A1/ru
Priority to PCT/EP2020/051268 priority patent/WO2020164863A1/en
Priority to CA3129896A priority patent/CA3129896A1/en
Priority to AU2020220593A priority patent/AU2020220593A1/en
Publication of EE01561U1 publication Critical patent/EE01561U1/et
Priority to US18/308,219 priority patent/US11899011B2/en
Priority to US18/417,845 priority patent/US20240192203A1/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/588—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with semiconductor nanocrystal label, e.g. quantum dots
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • G01N2021/6441—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks with two or more labels

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Nanotechnology (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Käesolev leiutis käsitleb meetodit vedelas proovis orgaaniliste analüütide tuvastamiseks ja kvantifitseerimiseks ning analüüsisubstraati analüüdi mõõtmiste tegemiseks. Nimetatud meetodit rakendatakse orgaaniliste analüütide ja mitmekihilisele analüüsisubstraadile immobiliseeritud selektiivsete sidumiskohtade vahelise spetsiifilise interaktsiooni kasutamisel, mis põhineb sellise analüüsisubstraadi fluorestsentsi indutseerimisel ja registreerimisel, biokeemiliste, geneetiliste ja keskkonnaalaste analüüside läbiviimiseks. Leiutise eesmärk on suurendada analüüdi tuvastamise tundlikkust, et määrata korraga proovis nii analüüdi olemasolu kui ka selle kontsentratsioon. Tuvastamine põhineb analüüdi molekuli spetsiifilisel interaktsioonil analüüsisubstraadi pinnale immobiliseeritud mitmekihilisenanostruktuuriga seotud sensormolekuli spetsiifilise sidumiskohaga.
EEU201900011U 2019-02-11 2019-02-11 Meetod vedelas proovis vähemalt ühe orgaanilise analüüdi tuvastamiseks ja kvantifitseerimiseks. EE01561U1 (et)

Priority Applications (9)

Application Number Priority Date Filing Date Title
EEU201900011U EE01561U1 (et) 2019-02-11 2019-02-11 Meetod vedelas proovis vähemalt ühe orgaanilise analüüdi tuvastamiseks ja kvantifitseerimiseks.
EP20703391.1A EP3924734A1 (en) 2019-02-11 2020-01-20 Selective optical detection of organic analytes in liquids
US17/251,536 US11650205B2 (en) 2019-02-11 2020-01-20 Selective optical detection of organic analytes in liquids
EA202192229A EA202192229A1 (ru) 2019-02-11 2020-01-20 Селективное оптическое обнаружение органических анализируемых веществ в жидкостях
PCT/EP2020/051268 WO2020164863A1 (en) 2019-02-11 2020-01-20 Selective optical detection of organic analytes in liquids
CA3129896A CA3129896A1 (en) 2019-02-11 2020-01-20 Selective optical detection of organic analytes in liquids
AU2020220593A AU2020220593A1 (en) 2019-02-11 2020-01-20 Selective optical detection of organic analytes in liquids
US18/308,219 US11899011B2 (en) 2019-02-11 2023-04-27 Selective optical detection of organic analytes in liquids
US18/417,845 US20240192203A1 (en) 2019-02-11 2024-01-19 Selective optical detection of organic analytes in liquids

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EEU201900011U EE01561U1 (et) 2019-02-11 2019-02-11 Meetod vedelas proovis vähemalt ühe orgaanilise analüüdi tuvastamiseks ja kvantifitseerimiseks.

Publications (1)

Publication Number Publication Date
EE01561U1 true EE01561U1 (et) 2022-03-15

Family

ID=69467499

Family Applications (1)

Application Number Title Priority Date Filing Date
EEU201900011U EE01561U1 (et) 2019-02-11 2019-02-11 Meetod vedelas proovis vähemalt ühe orgaanilise analüüdi tuvastamiseks ja kvantifitseerimiseks.

Country Status (7)

Country Link
US (3) US11650205B2 (et)
EP (1) EP3924734A1 (et)
AU (1) AU2020220593A1 (et)
CA (1) CA3129896A1 (et)
EA (1) EA202192229A1 (et)
EE (1) EE01561U1 (et)
WO (1) WO2020164863A1 (et)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EE01561U1 (et) * 2019-02-11 2022-03-15 Qanikdx Oü Meetod vedelas proovis vähemalt ühe orgaanilise analüüdi tuvastamiseks ja kvantifitseerimiseks.
CN114674900B (zh) * 2022-04-02 2023-09-22 湖北大学 基于小分子探针的光电化学微传感器及其制备方法与应用

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US20090227043A1 (en) * 2008-02-19 2009-09-10 Wei Huang Fluorescence Resonance Energy Transfer Assay Based on Modified Solid Surface
KR100970584B1 (ko) * 2008-02-28 2010-07-16 한국과학기술원 당단백질 분석용 바이오칩 세트

Also Published As

Publication number Publication date
US11899011B2 (en) 2024-02-13
US20240192203A1 (en) 2024-06-13
US20210356463A1 (en) 2021-11-18
CA3129896A1 (en) 2020-08-20
AU2020220593A1 (en) 2021-10-07
WO2020164863A1 (en) 2020-08-20
EA202192229A1 (ru) 2021-12-20
EP3924734A1 (en) 2021-12-22
US11650205B2 (en) 2023-05-16
US20230258631A1 (en) 2023-08-17

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Legal Events

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EXFP Utility model extended to 8 or 10 years after payment of fee

Expiry date: 20270211