ECSP22051701A - Anticuerpos anti-cd73 y usos de estos - Google Patents
Anticuerpos anti-cd73 y usos de estosInfo
- Publication number
- ECSP22051701A ECSP22051701A ECSENADI202251701A ECDI202251701A ECSP22051701A EC SP22051701 A ECSP22051701 A EC SP22051701A EC SENADI202251701 A ECSENADI202251701 A EC SENADI202251701A EC DI202251701 A ECDI202251701 A EC DI202251701A EC SP22051701 A ECSP22051701 A EC SP22051701A
- Authority
- EC
- Ecuador
- Prior art keywords
- antibodies
- vectors
- cells
- methods
- nucleic acids
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Fats And Perfumes (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062956847P | 2020-01-03 | 2020-01-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP22051701A true ECSP22051701A (es) | 2022-08-31 |
Family
ID=74347717
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSENADI202251701A ECSP22051701A (es) | 2020-01-03 | 2022-07-01 | Anticuerpos anti-cd73 y usos de estos |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US12018089B2 (enExample) |
| EP (1) | EP4084825A1 (enExample) |
| JP (1) | JP2023509448A (enExample) |
| KR (1) | KR20220121850A (enExample) |
| CN (1) | CN115135341A (enExample) |
| AR (1) | AR120936A1 (enExample) |
| AU (1) | AU2020417804A1 (enExample) |
| BR (1) | BR112022013236A2 (enExample) |
| CA (1) | CA3166533A1 (enExample) |
| CL (2) | CL2022001769A1 (enExample) |
| CO (1) | CO2022009248A2 (enExample) |
| CR (1) | CR20220317A (enExample) |
| EC (1) | ECSP22051701A (enExample) |
| IL (1) | IL294436A (enExample) |
| MX (1) | MX2022007575A (enExample) |
| PE (1) | PE20221409A1 (enExample) |
| PH (1) | PH12022551636A1 (enExample) |
| TW (1) | TWI873265B (enExample) |
| WO (1) | WO2021138467A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI877770B (zh) | 2018-02-27 | 2025-03-21 | 美商英塞特公司 | 作為a2a / a2b抑制劑之咪唑并嘧啶及三唑并嘧啶 |
| EP3810610A1 (en) | 2018-05-18 | 2021-04-28 | Incyte Corporation | Fused pyrimidine derivatives as a2a / a2b inhibitors |
| WO2020010197A1 (en) | 2018-07-05 | 2020-01-09 | Incyte Corporation | Fused pyrazine derivatives as a2a / a2b inhibitors |
| TWI829857B (zh) | 2019-01-29 | 2024-01-21 | 美商英塞特公司 | 作為a2a / a2b抑制劑之吡唑并吡啶及三唑并吡啶 |
| PE20221409A1 (es) | 2020-01-03 | 2022-09-20 | Incyte Corp | Anticuerpos anti-cd73 y usos de estos |
| TW202135823A (zh) | 2020-01-03 | 2021-10-01 | 美商英塞特公司 | Cd73抑制劑及a2a/a2b腺苷受體抑制劑組合療法 |
| TW202241441A (zh) * | 2020-12-29 | 2022-11-01 | 美商英塞特公司 | 包含a2a/a2b抑制劑、pd-1/pd-l1抑制劑及抗cd73抗體之組合療法 |
| CN113025567A (zh) * | 2021-03-31 | 2021-06-25 | 中国人民解放军陆军特色医学中心 | 一种椎间盘单细胞的分离方法 |
| EP4413366A4 (en) * | 2021-10-08 | 2025-09-10 | Tiberias Tech Hk Limited | TIBTECH METHODS AND COMPOSITIONS FOR THE DETECTION OF CDH17 |
| JP2025512384A (ja) | 2022-04-13 | 2025-04-17 | ギリアード サイエンシーズ, インコーポレイテッド | Trop-2発現がんを治療するための併用療法 |
| WO2024040194A1 (en) | 2022-08-17 | 2024-02-22 | Capstan Therapeutics, Inc. | Conditioning for in vivo immune cell engineering |
| AU2024279278A1 (en) | 2023-05-31 | 2025-12-18 | Capstan Therapeutics, Inc. | Lipid nanoparticle formulations and compositions |
| WO2025025190A1 (zh) * | 2023-08-03 | 2025-02-06 | 贝达药业股份有限公司 | 抗cd73抗体及其应用 |
| WO2025076113A1 (en) | 2023-10-05 | 2025-04-10 | Capstan Therapeutics, Inc. | Ionizable cationic lipids with conserved spacing and lipid nanoparticles |
| US20250127728A1 (en) | 2023-10-05 | 2025-04-24 | Capstan Therapeutics, Inc. | Constrained Ionizable Cationic Lipids and Lipid Nanoparticles |
| WO2025135233A1 (ko) * | 2023-12-21 | 2025-06-26 | ㈜지아이이노베이션 | Cd73에 특이적으로 결합하는 항체 및 이의 용도 |
| WO2025137640A1 (en) | 2023-12-22 | 2025-06-26 | Gilead Sciences, Inc. | Azaspiro wrn inhibitors |
| US20250302763A1 (en) | 2024-02-22 | 2025-10-02 | Capstan Therapeutics, Inc. | Immune engineering amplification |
| WO2025217452A1 (en) | 2024-04-11 | 2025-10-16 | Capstan Therapeutics, Inc. | Constrained ionizable cationic lipids and lipid nanoparticles |
| WO2025217454A2 (en) | 2024-04-11 | 2025-10-16 | Capstan Therapeutics, Inc. | Ionizable cationic lipids and lipid nanoparticles |
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| US4634665A (en) | 1980-02-25 | 1987-01-06 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4399216A (en) | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
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| DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
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| RU2754058C2 (ru) | 2016-12-13 | 2021-08-26 | Астеллас Фарма Инк. | Антитело к cd73 человека |
| CA3045376C (en) | 2017-01-24 | 2022-08-30 | I-Mab | Anti-cd73 antibodies and uses thereof |
| US20210107989A1 (en) | 2017-04-04 | 2021-04-15 | Corvus Pharmaceuticals, Inc. | Methods for treating cd73hi tumors |
| US11530273B2 (en) | 2017-05-23 | 2022-12-20 | Helmholtz Zentrum München—Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) | Anti-CD73 monoclonal antibody, encoding nucleic acids and method for producing |
| EP3642240A1 (en) | 2017-06-22 | 2020-04-29 | Novartis AG | Antibody molecules to cd73 and uses thereof |
| MY204117A (en) | 2017-06-22 | 2024-08-08 | Novartis Ag | Antibody molecules to cd73 and uses thereof |
| TWI877770B (zh) | 2018-02-27 | 2025-03-21 | 美商英塞特公司 | 作為a2a / a2b抑制劑之咪唑并嘧啶及三唑并嘧啶 |
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| BR112020020826A2 (pt) | 2018-04-12 | 2021-01-19 | Bristol-Myers Squibb Company | Terapia de combinação anticâncer com anticorpo antagonista de cd73 e anticorpo antagonista do eixo pd-1/pd-l1 |
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| CA3174033A1 (en) | 2020-04-09 | 2021-10-14 | Sang Hoon Cha | Monoclonal antibodies and antigen binding fragments thereof for suppressing cd73 immune checkpoint and uses thereof |
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| JP2023532234A (ja) | 2020-06-22 | 2023-07-27 | イノベント バイオロジクス(スーチョウ)カンパニー,リミティド | 抗cd73抗体とその用途 |
| TW202241441A (zh) | 2020-12-29 | 2022-11-01 | 美商英塞特公司 | 包含a2a/a2b抑制劑、pd-1/pd-l1抑制劑及抗cd73抗體之組合療法 |
-
2020
- 2020-12-30 PE PE2022001337A patent/PE20221409A1/es unknown
- 2020-12-30 CN CN202080096659.5A patent/CN115135341A/zh active Pending
- 2020-12-30 AR ARP200103688A patent/AR120936A1/es unknown
- 2020-12-30 KR KR1020227025615A patent/KR20220121850A/ko not_active Withdrawn
- 2020-12-30 CA CA3166533A patent/CA3166533A1/en active Pending
- 2020-12-30 EP EP20848762.9A patent/EP4084825A1/en not_active Withdrawn
- 2020-12-30 JP JP2022540938A patent/JP2023509448A/ja not_active Ceased
- 2020-12-30 PH PH1/2022/551636A patent/PH12022551636A1/en unknown
- 2020-12-30 BR BR112022013236A patent/BR112022013236A2/pt unknown
- 2020-12-30 MX MX2022007575A patent/MX2022007575A/es unknown
- 2020-12-30 AU AU2020417804A patent/AU2020417804A1/en not_active Withdrawn
- 2020-12-30 WO PCT/US2020/067533 patent/WO2021138467A1/en not_active Ceased
- 2020-12-30 TW TW109146785A patent/TWI873265B/zh active
- 2020-12-30 US US17/138,279 patent/US12018089B2/en active Active
- 2020-12-30 IL IL294436A patent/IL294436A/en unknown
- 2020-12-30 CR CR20220317A patent/CR20220317A/es unknown
-
2022
- 2022-06-28 CL CL2022001769A patent/CL2022001769A1/es unknown
- 2022-07-01 CO CONC2022/0009248A patent/CO2022009248A2/es unknown
- 2022-07-01 EC ECSENADI202251701A patent/ECSP22051701A/es unknown
-
2024
- 2024-05-20 US US18/668,914 patent/US20240352143A1/en active Pending
- 2024-07-24 CL CL2024002235A patent/CL2024002235A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CL2024002235A1 (es) | 2024-12-27 |
| BR112022013236A2 (pt) | 2022-09-06 |
| CR20220317A (es) | 2022-09-02 |
| KR20220121850A (ko) | 2022-09-01 |
| JP2023509448A (ja) | 2023-03-08 |
| PE20221409A1 (es) | 2022-09-20 |
| CL2022001769A1 (es) | 2023-01-20 |
| US12018089B2 (en) | 2024-06-25 |
| AU2020417804A1 (en) | 2022-07-21 |
| US20210230293A1 (en) | 2021-07-29 |
| IL294436A (en) | 2022-09-01 |
| AR120936A1 (es) | 2022-03-30 |
| CO2022009248A2 (es) | 2022-08-19 |
| TWI873265B (zh) | 2025-02-21 |
| PH12022551636A1 (en) | 2024-01-08 |
| CN115135341A (zh) | 2022-09-30 |
| MX2022007575A (es) | 2022-09-23 |
| EP4084825A1 (en) | 2022-11-09 |
| WO2021138467A1 (en) | 2021-07-08 |
| US20240352143A1 (en) | 2024-10-24 |
| TW202128768A (zh) | 2021-08-01 |
| CA3166533A1 (en) | 2021-07-08 |
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