ECSP13012473A - Forma de dosificación resistente a alteración que comprende un polímero aniónico - Google Patents

Forma de dosificación resistente a alteración que comprende un polímero aniónico

Info

Publication number
ECSP13012473A
ECSP13012473A ECSP13012473A ECSP13012473A EC SP13012473 A ECSP13012473 A EC SP13012473A EC SP13012473 A ECSP13012473 A EC SP13012473A EC SP13012473 A ECSP13012473 A EC SP13012473A
Authority
EC
Ecuador
Prior art keywords
dosage form
anionic polymer
form including
resistant dosage
polysaccharide
Prior art date
Application number
Other languages
English (en)
Inventor
Johannes Bartholomäus
Lutz Barnscheid
Sebastian Schwier
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43897069&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP13012473(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of ECSP13012473A publication Critical patent/ECSP13012473A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La invención se refiere a una forma de dosificación farmacéutica que muestra una resistencia a rompimiento de al menos 500 N, dicha forma de dosificación conteniendo un ingrediente farmacológicamente activo (A); un polisacárido aniónico (B) que se obtiene al introducir grupos funcionales aniónicos, en forma protonada o una sal fisiológicamente aceptable del mismo, en un polisacárido; y un óxido de polialquileno (C); en donde el ingrediente farmacológicamente activo (A) está presente en una matriz de liberación controlada comprendiendo el polisacárido aniónico (B) y el óxido de polialquileno (C).
ECSP13012473 2010-09-02 2013-03-01 Forma de dosificación resistente a alteración que comprende un polímero aniónico ECSP13012473A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP10009124 2010-09-02

Publications (1)

Publication Number Publication Date
ECSP13012473A true ECSP13012473A (es) 2013-04-30

Family

ID=43897069

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP13012473 ECSP13012473A (es) 2010-09-02 2013-03-01 Forma de dosificación resistente a alteración que comprende un polímero aniónico

Country Status (22)

Country Link
US (1) US20120059065A1 (es)
EP (1) EP2611428B1 (es)
JP (1) JP5925778B2 (es)
KR (1) KR20130097201A (es)
CN (2) CN107308124A (es)
AR (1) AR082861A1 (es)
AU (1) AU2011297954B2 (es)
BR (1) BR112013005195A2 (es)
CA (1) CA2808988C (es)
CL (1) CL2013000423A1 (es)
CO (1) CO6670598A2 (es)
EC (1) ECSP13012473A (es)
ES (1) ES2534847T3 (es)
HK (1) HK1184389A1 (es)
IL (1) IL224616A (es)
MX (1) MX340427B (es)
NZ (1) NZ607479A (es)
PE (1) PE20131125A1 (es)
PL (1) PL2611428T3 (es)
RU (1) RU2013114411A (es)
TW (1) TWI501788B (es)
WO (1) WO2012028317A1 (es)

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US8075872B2 (en) 2003-08-06 2011-12-13 Gruenenthal Gmbh Abuse-proofed dosage form
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PT2736497T (pt) 2011-07-29 2017-11-30 Gruenenthal Gmbh Comprimido resistente a adulteração proporcionando libertação imediata de fármaco
MX348491B (es) 2011-07-29 2017-06-15 Gruenenthal Gmbh Tableta a prueba de manipulacion que proporciona liberacion inmediata de fármaco.
WO2013127831A1 (en) 2012-02-28 2013-09-06 Grünenthal GmbH Tamper-resistant dosage form comprising pharmacologically active compound and anionic polymer
AU2013248351B2 (en) 2012-04-18 2018-04-26 Grunenthal Gmbh Tamper resistant and dose-dumping resistant pharmaceutical dosage form
US10064945B2 (en) 2012-05-11 2018-09-04 Gruenenthal Gmbh Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
WO2014006004A1 (en) 2012-07-06 2014-01-09 Egalet Ltd. Abuse deterrent pharmaceutical compositions for controlled release
BR112015000320B1 (pt) 2012-07-12 2023-03-07 SpecGx LLC Composições farmacêuticas dissuasivas de abuso e seu processo de preparação
AR096439A1 (es) 2013-05-29 2015-12-30 Gruenenthal Gmbh Forma de dosificación resistente al uso indebido que contiene una o más partículas
US10154966B2 (en) 2013-05-29 2018-12-18 Grünenthal GmbH Tamper-resistant dosage form containing one or more particles
EA032465B1 (ru) 2013-07-12 2019-05-31 Грюненталь Гмбх Защищенная от применения не по назначению пероральная фармацевтическая лекарственная форма, содержащая этиленвинилацетатный полимер, и способ ее изготовления
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Also Published As

Publication number Publication date
EP2611428A1 (en) 2013-07-10
CA2808988C (en) 2018-05-01
BR112013005195A2 (pt) 2016-07-12
CO6670598A2 (es) 2013-05-15
CN103179956A (zh) 2013-06-26
CN107308124A (zh) 2017-11-03
CA2808988A1 (en) 2012-03-08
TWI501788B (zh) 2015-10-01
KR20130097201A (ko) 2013-09-02
MX340427B (es) 2016-07-08
AU2011297954B2 (en) 2014-05-15
EP2611428B1 (en) 2015-01-14
CL2013000423A1 (es) 2013-04-12
IL224616A (en) 2017-06-29
TW201212954A (en) 2012-04-01
ES2534847T3 (es) 2015-04-29
US20120059065A1 (en) 2012-03-08
HK1184389A1 (en) 2014-01-24
AR082861A1 (es) 2013-01-16
JP5925778B2 (ja) 2016-05-25
PE20131125A1 (es) 2013-10-21
PL2611428T3 (pl) 2015-06-30
JP2013536809A (ja) 2013-09-26
RU2013114411A (ru) 2014-10-10
MX2013002120A (es) 2013-04-03
AU2011297954A1 (en) 2013-03-14
NZ607479A (en) 2015-06-26
WO2012028317A1 (en) 2012-03-08

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