ECSP088635A - Formulaciones orales que comprenden tigeciclina - Google Patents
Formulaciones orales que comprenden tigeciclinaInfo
- Publication number
- ECSP088635A ECSP088635A EC2008008635A ECSP088635A ECSP088635A EC SP088635 A ECSP088635 A EC SP088635A EC 2008008635 A EC2008008635 A EC 2008008635A EC SP088635 A ECSP088635 A EC SP088635A EC SP088635 A ECSP088635 A EC SP088635A
- Authority
- EC
- Ecuador
- Prior art keywords
- tigecicline
- oral formulations
- tigecyclines
- composition
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Se describen en la presente composiciones farmacéuticas que comprenden tigeciclinas para la administración oral. La composición puede comprender tigeciclina que tiene por lo menos un revestimiento entérico.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US75303505P | 2005-12-22 | 2005-12-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP088635A true ECSP088635A (es) | 2008-08-29 |
Family
ID=37964562
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EC2008008635A ECSP088635A (es) | 2005-12-22 | 2008-07-18 | Formulaciones orales que comprenden tigeciclina |
Country Status (14)
Country | Link |
---|---|
US (1) | US20080014256A1 (es) |
EP (1) | EP1965770A2 (es) |
KR (1) | KR20080080205A (es) |
CN (1) | CN101340895A (es) |
AU (1) | AU2006331688A1 (es) |
BR (1) | BRPI0620646A2 (es) |
CA (1) | CA2632213A1 (es) |
CR (1) | CR10124A (es) |
EC (1) | ECSP088635A (es) |
GT (1) | GT200800107A (es) |
IL (1) | IL191789A0 (es) |
NO (1) | NO20082547L (es) |
RU (1) | RU2008120672A (es) |
WO (1) | WO2007075794A2 (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006084058A2 (en) | 2005-02-03 | 2006-08-10 | The General Hospital Corporation | Method for treating gefitinib resistant cancer |
WO2007056118A1 (en) | 2005-11-04 | 2007-05-18 | Wyeth | Antineoplastic combinations with mtor inhibitor, herceptin, and/or hki-272 |
US8022216B2 (en) | 2007-10-17 | 2011-09-20 | Wyeth Llc | Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof |
US9107929B2 (en) | 2008-05-01 | 2015-08-18 | Ranbaxy Laboratories Limited | Stable parenteral formulations of tigecycline |
EP2915532B1 (en) | 2008-06-17 | 2016-10-19 | Wyeth LLC | Antineoplastic combinations containing hki-272 and vinorelbine |
ES2614912T3 (es) | 2008-08-04 | 2017-06-02 | Wyeth Llc | Combinaciones antineoplásicas de 4-anilino-3-cianoquinolinas y capecitabina |
EP3000467B1 (en) | 2009-04-06 | 2023-03-01 | Wyeth LLC | Treatment regimen utilizing neratinib for breast cancer |
CN102724962B (zh) | 2009-11-09 | 2017-05-17 | 惠氏有限责任公司 | 包衣药物球状体及其用于消除或减少病症比如呕吐和腹泻的用途 |
DK2568987T3 (en) | 2010-05-12 | 2017-02-20 | Rempex Pharmaceuticals Inc | Tetracycline COMPOSITIONS |
US9833411B2 (en) * | 2015-01-12 | 2017-12-05 | Enteris Biopharma, Inc. | Solid oral dosage forms |
US20210161918A1 (en) * | 2018-01-10 | 2021-06-03 | The University Of North Carolina At Chapel Hill | Tigecycline for topical treatment of root canal space |
CN111166729A (zh) * | 2020-03-19 | 2020-05-19 | 珠海赛隆药业股份有限公司 | 一种口服的替加环素肠溶微球及其制备方法 |
CN112577917A (zh) * | 2020-12-28 | 2021-03-30 | 瀚晖制药有限公司 | 注射用替加环素中有色杂质的检测方法 |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3026248A (en) * | 1959-09-11 | 1962-03-20 | Pfizer & Co C | Thioglycerol and formaldehyde sulfoxylate stabilized tetracycline antibiotics in polyhydric alcohol solvents |
US3219529A (en) * | 1962-10-04 | 1965-11-23 | American Cyanamid Co | Stable tetracycline solutions |
US4837030A (en) * | 1987-10-06 | 1989-06-06 | American Cyanamid Company | Novel controlled release formulations of tetracycline compounds |
US5494903A (en) * | 1991-10-04 | 1996-02-27 | American Cyanamid Company | 7-substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines |
US5281628A (en) * | 1991-10-04 | 1994-01-25 | American Cyanamid Company | 9-amino-7-(substituted)-6-demethyl-6-deoxytetracyclines |
US5167964A (en) * | 1992-02-14 | 1992-12-01 | Warner-Lambert Company | Semi-enteric drug delivery systems and methods for preparing same |
US5420272A (en) * | 1992-08-13 | 1995-05-30 | American Cyanamid Company | 7-(substituted)-8-(substituted)-9-](substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines |
SG47520A1 (en) * | 1992-08-13 | 1998-04-17 | American Cyanamid Co | New method for the production of 9-amino-6-demethyl-6-deoxytetracycline |
US5328902A (en) * | 1992-08-13 | 1994-07-12 | American Cyanamid Co. | 7-(substituted)-9-[(substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines |
MX9603508A (es) * | 1994-02-17 | 1997-03-29 | Pfizer | Analogos de la doxiciclina. |
US5567693A (en) * | 1994-12-13 | 1996-10-22 | American Cyanamid Company | Method for inhibiting angiogenesis, proliferation of endothelial or tumor cells and tumor growth |
US6063775A (en) * | 1997-04-29 | 2000-05-16 | Berman; Charles L. | Retardation of metalloproteinase incidental to HIV and/or AIDS |
US5908838A (en) * | 1998-02-19 | 1999-06-01 | Medics Pharmaceutical Corporation | Method for the treatment of acne |
US6015803A (en) * | 1998-05-04 | 2000-01-18 | Wirostko; Emil | Antibiotic treatment of age-related macular degeneration |
US6015804A (en) * | 1998-09-11 | 2000-01-18 | The Research Foundation Of State University Of New York | Method of using tetracycline compounds to enhance interleukin-10 production |
US5998390A (en) * | 1998-09-28 | 1999-12-07 | The Research Foundation Of State University Of New York | Combination of bisphosphonate and tetracycline |
US6506740B1 (en) * | 1998-11-18 | 2003-01-14 | Robert A. Ashley | 4-dedimethylaminotetracycline derivatives |
US20040131628A1 (en) * | 2000-03-08 | 2004-07-08 | Bratzler Robert L. | Nucleic acids for the treatment of disorders associated with microorganisms |
BR0109725A (pt) * | 2000-03-31 | 2003-02-04 | Tufts College | Composto de tetraciclina substituìdo, método para tratar um estado responsivo a tetraciclina em um mamìfero, composição farmacêutica, método para sintetizar um composto de tetraciclina 7- ou 9-substituìdo, e, intermediário reativo |
WO2002004406A2 (en) * | 2000-07-07 | 2002-01-17 | Trustees Of Tufts College | 9-substituted minocycline compounds |
HUP0301163A3 (en) * | 2000-07-07 | 2008-08-28 | Tufts College | 7-substituted tetracycline dervatives, pharmaceutical compositions containing them and their use |
CZ20032780A3 (cs) * | 2001-03-13 | 2004-01-14 | Paratek Pharmaceuticals, Inc. | 7,9- Substituované tetracyklinové sloučeniny |
CA2457234A1 (en) * | 2001-03-14 | 2002-09-19 | Mark L. Nelson | Substituted tetracycline compounds as antifungal agents |
WO2003005971A2 (en) * | 2001-07-13 | 2003-01-23 | Paratek Pharmaceuticals, Inc. | Tetracycline compounds having target therapeutic activities |
EP2322501B1 (en) * | 2002-01-08 | 2015-08-05 | Paratek Pharmaceuticals, Inc. | 4-dedimethylamino tetracycline compounds |
US6958161B2 (en) * | 2002-04-12 | 2005-10-25 | F H Faulding & Co Limited | Modified release coated drug preparation |
KR101089429B1 (ko) * | 2002-07-12 | 2011-12-07 | 파라테크 파마슈티컬스, 인크. | 3, 10, 및 12a 치환된 테트라시클린 화합물 |
WO2004017925A2 (en) * | 2002-08-23 | 2004-03-04 | Genome Therapeutics Corporation | Methods and reagents for preventing bacteremias |
EP1545453B1 (en) * | 2002-08-29 | 2009-11-18 | ActivBiotics Pharma LLC | Rifalazil for treating infections of clostridium difficile |
US20050148553A1 (en) * | 2003-09-05 | 2005-07-07 | Testa Raymond T. | Use of tigecycline, alone, or in combination with rifampin to treat osteomyelitis and/or septic arthritis |
GB2414668B (en) * | 2004-06-03 | 2009-07-29 | Dexcel Ltd | Tetracycline modified release delivery system |
-
2006
- 2006-12-20 WO PCT/US2006/048621 patent/WO2007075794A2/en active Application Filing
- 2006-12-20 RU RU2008120672/15A patent/RU2008120672A/ru not_active Application Discontinuation
- 2006-12-20 AU AU2006331688A patent/AU2006331688A1/en not_active Abandoned
- 2006-12-20 EP EP06847833A patent/EP1965770A2/en not_active Withdrawn
- 2006-12-20 BR BRPI0620646-8A patent/BRPI0620646A2/pt not_active Application Discontinuation
- 2006-12-20 CN CNA2006800482101A patent/CN101340895A/zh active Pending
- 2006-12-20 KR KR1020087017661A patent/KR20080080205A/ko not_active Application Discontinuation
- 2006-12-20 CA CA002632213A patent/CA2632213A1/en not_active Abandoned
- 2006-12-21 US US11/642,509 patent/US20080014256A1/en not_active Abandoned
-
2008
- 2008-05-28 IL IL191789A patent/IL191789A0/en unknown
- 2008-05-30 NO NO20082547A patent/NO20082547L/no unknown
- 2008-06-17 GT GT200800107A patent/GT200800107A/es unknown
- 2008-06-27 CR CR10124A patent/CR10124A/es not_active Application Discontinuation
- 2008-07-18 EC EC2008008635A patent/ECSP088635A/es unknown
Also Published As
Publication number | Publication date |
---|---|
US20080014256A1 (en) | 2008-01-17 |
CA2632213A1 (en) | 2007-07-05 |
GT200800107A (es) | 2008-11-19 |
RU2008120672A (ru) | 2010-01-27 |
WO2007075794A2 (en) | 2007-07-05 |
EP1965770A2 (en) | 2008-09-10 |
NO20082547L (no) | 2008-09-22 |
AU2006331688A1 (en) | 2007-07-05 |
CN101340895A (zh) | 2009-01-07 |
IL191789A0 (en) | 2008-12-29 |
CR10124A (es) | 2008-09-23 |
BRPI0620646A2 (pt) | 2011-11-22 |
KR20080080205A (ko) | 2008-09-02 |
WO2007075794A3 (en) | 2007-08-16 |
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