ECSP066590A - Nitrooxiderivados de drogas antihipertensivas - Google Patents

Nitrooxiderivados de drogas antihipertensivas

Info

Publication number
ECSP066590A
ECSP066590A EC2006006590A ECSP066590A ECSP066590A EC SP066590 A ECSP066590 A EC SP066590A EC 2006006590 A EC2006006590 A EC 2006006590A EC SP066590 A ECSP066590 A EC SP066590A EC SP066590 A ECSP066590 A EC SP066590A
Authority
EC
Ecuador
Prior art keywords
nitrooxiderivates
antihipertensive
drugs
pharmaceutical
ono2
Prior art date
Application number
EC2006006590A
Other languages
English (en)
Inventor
Soldato Piero Del
Ennio Ongini
Francesca Benedini
Original Assignee
Nicox Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicox Sa filed Critical Nicox Sa
Publication of ECSP066590A publication Critical patent/ECSP066590A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/10—1,2,5-Thiadiazoles; Hydrogenated 1,2,5-thiadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Nitrooxiderivados de bloqueadores b-adrenérgicos de fórmula general (I): A-(Y-ONO2)s y enantiómeros y diastereoisómeros y sales aceptables para uso farmacéutico de los mismos, composiciones farmacéuticas que los contienen y su uso para el tratamiento de hipertensión, enfermedades cardiovasculares, glaucoma, migraña y enfermedades vasculares.
EC2006006590A 2003-12-02 2006-05-29 Nitrooxiderivados de drogas antihipertensivas ECSP066590A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03104485 2003-12-02

Publications (1)

Publication Number Publication Date
ECSP066590A true ECSP066590A (es) 2006-10-17

Family

ID=34639310

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2006006590A ECSP066590A (es) 2003-12-02 2006-05-29 Nitrooxiderivados de drogas antihipertensivas

Country Status (21)

Country Link
US (1) US20070060586A1 (es)
EP (1) EP1748994B1 (es)
JP (1) JP2007513113A (es)
KR (1) KR20060120164A (es)
CN (1) CN1906182A (es)
AP (1) AP2006003622A0 (es)
AR (1) AR047264A1 (es)
AT (1) ATE423107T1 (es)
AU (1) AU2004295105A1 (es)
BR (1) BRPI0417182A (es)
CA (1) CA2548127A1 (es)
DE (1) DE602004019579D1 (es)
EA (1) EA200600891A1 (es)
EC (1) ECSP066590A (es)
ES (1) ES2320002T3 (es)
IL (1) IL176061A0 (es)
MA (1) MA28224A1 (es)
NO (1) NO20062527L (es)
TN (1) TNSN06151A1 (es)
WO (1) WO2005054218A1 (es)
ZA (1) ZA200604463B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004528337A (ja) 2001-05-02 2004-09-16 ニトロメド インコーポレーテッド ニトロソ化およびニトロシル化ネビボロール、ならびにその代謝産物、組成物、および使用方法
JP2009525970A (ja) 2006-02-06 2009-07-16 ニコックス エス エイ α２−アドレナリン受容体アゴニストとしてのアプラクロニジンおよびブリモドニジンのニトロオキシ含有誘導体
WO2007090733A1 (en) * 2006-02-06 2007-08-16 Nicox S.A. Nitrooxy derivatives suitable as alpha2 adrenergic receptor agonists
WO2021195126A1 (en) 2020-03-24 2021-09-30 Burnet Michael W Anti-infective and anti-viral compounds and compositions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3443998A1 (de) * 1984-12-01 1986-06-05 Boehringer Mannheim Gmbh, 6800 Mannheim Amino-propanol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte
ES2065291B1 (es) * 1993-07-30 1995-10-01 Prodesfarma Sa "nitrato esteres de 1-ariloxi-3-alquilamino-2-propanoles, utilizacion y composicion farmaceutica correspondiente"
IT1295694B1 (it) * 1996-11-14 1999-05-27 Nicox Sa Nitrossi derivati per la preparazione di medicamenti ad attivita antitrombinica
IT1311923B1 (it) * 1999-04-13 2002-03-20 Nicox Sa Composti farmaceutici.
IT1314184B1 (it) * 1999-08-12 2002-12-06 Nicox Sa Composizioni farmaceutiche per la terapia di condizioni di stressossidativo

Also Published As

Publication number Publication date
CA2548127A1 (en) 2005-06-16
MA28224A1 (fr) 2006-10-02
JP2007513113A (ja) 2007-05-24
EP1748994A1 (en) 2007-02-07
EP1748994B1 (en) 2009-02-18
ZA200604463B (en) 2007-04-25
EA200600891A1 (ru) 2006-10-27
WO2005054218A1 (en) 2005-06-16
DE602004019579D1 (de) 2009-04-02
AR047264A1 (es) 2006-01-11
BRPI0417182A (pt) 2007-03-06
CN1906182A (zh) 2007-01-31
KR20060120164A (ko) 2006-11-24
NO20062527L (no) 2006-06-30
AU2004295105A1 (en) 2005-06-16
TNSN06151A1 (en) 2007-11-15
IL176061A0 (en) 2006-10-05
AP2006003622A0 (en) 2006-06-30
US20070060586A1 (en) 2007-03-15
ES2320002T3 (es) 2009-05-18
ATE423107T1 (de) 2009-03-15

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