ECSP045063A - Formas de dosificacion, dispositivo y procedimientos de tratamiento - Google Patents

Formas de dosificacion, dispositivo y procedimientos de tratamiento

Info

Publication number
ECSP045063A
ECSP045063A EC2004005063A ECSP045063A ECSP045063A EC SP045063 A ECSP045063 A EC SP045063A EC 2004005063 A EC2004005063 A EC 2004005063A EC SP045063 A ECSP045063 A EC SP045063A EC SP045063 A ECSP045063 A EC SP045063A
Authority
EC
Ecuador
Prior art keywords
formulation
rumen
predetermined
quantities
active agent
Prior art date
Application number
EC2004005063A
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=3832213&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP045063(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of ECSP045063A publication Critical patent/ECSP045063A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0068—Rumen, e.g. rumen bolus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Inorganic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Un elemento de dosificación de liberación controlada adaptado para insertarse en y retenerse en el rumen de un animal rumiante, comprendiendo dicho elemento: a) una o más cantidades pequeñas y predeterminadas de al menos una primera formulación que comprende al menos un primer agente activo, estando dicha formulación adaptada para disolverse en los fluidos del rumen a una velocidad tal que la disolución de cada una de dichas una o más cantidades de la primera formulación proporciona un episodio en pulsos de liberación de dicho primer agente activo en el rumen; b) una o más cantidades predeterminadas de al menos una segunda formulación adaptada para disolverse a una velocidad controlada en los fluidos del rumen; en el que dichas una o más cantidades de la primera formulación se proporcionan en una o más localizaciones predeterminadas dentro del elemento respecto de dichas una o más cantidades de la segunda formulación para una o más liberaciones retardadas de al menos dicho primer agente activo en dicho rumen a tiempos predeterminados antes, durante y después, o cualquier combinación del mismo, de un periodo de tiempo extenso predeterminado definido por dicha segunda formulación; y c) opcionalmente, al menos una tercera formulación que se disuelve a una tercera velocidad de disolución en fluidos del rumen.
EC2004005063A 2001-10-19 2004-04-15 Formas de dosificacion, dispositivo y procedimientos de tratamiento ECSP045063A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPR8390A AUPR839001A0 (en) 2001-10-19 2001-10-19 Dosage form, device and methods of treatment

Publications (1)

Publication Number Publication Date
ECSP045063A true ECSP045063A (es) 2004-05-28

Family

ID=3832213

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2004005063A ECSP045063A (es) 2001-10-19 2004-04-15 Formas de dosificacion, dispositivo y procedimientos de tratamiento

Country Status (22)

Country Link
US (1) US20050064032A1 (es)
EP (1) EP1448151A4 (es)
JP (1) JP2005510485A (es)
KR (1) KR20050037410A (es)
CN (1) CN1571663A (es)
AR (1) AR037116A1 (es)
AU (5) AUPR839001A0 (es)
BR (1) BR0212975A (es)
CA (1) CA2463674A1 (es)
CR (1) CR7312A (es)
EA (1) EA005778B1 (es)
EC (1) ECSP045063A (es)
HR (1) HRP20040231A2 (es)
HU (1) HUP0401808A3 (es)
IL (1) IL160754A0 (es)
MX (1) MXPA04003679A (es)
NO (1) NO20041941L (es)
NZ (1) NZ531672A (es)
PE (1) PE20030519A1 (es)
PL (1) PL368387A1 (es)
WO (1) WO2003033031A1 (es)
ZA (1) ZA200403743B (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRN20030021A1 (it) * 2003-07-21 2005-01-22 Ascor Chimici Srl Composizione di materia comprendente particelle contenenti cloruro di colina da somministrare in forma ruminalmente protetta e post-ruminalmente efficace.
ITMI20041820A1 (it) * 2004-09-24 2004-12-24 Ascor Chimici Srl Composizione in micro-pellets a rilascio controllato di sostanze fisiologicamente attive, procedimento di preparazione e relativo impiego nel settore zootecnico.
US20060246003A1 (en) * 2004-12-27 2006-11-02 Eisai Co. Ltd. Composition containing anti-dementia drug
US20060280789A1 (en) * 2004-12-27 2006-12-14 Eisai Research Institute Sustained release formulations
US20090208579A1 (en) * 2004-12-27 2009-08-20 Eisai R & D Management Co., Ltd. Matrix Type Sustained-Release Preparation Containing Basic Drug or Salt Thereof, and Method for Manufacturing the Same
US8481565B2 (en) * 2004-12-27 2013-07-09 Eisai R&D Management Co., Ltd. Method for stabilizing anti-dementia drug
NZ554260A (en) * 2007-09-30 2010-05-28 Agres Ltd Selenomethionine andor selenocysteine administration to non-human animals to increase selenium content in protein sources
WO2010126857A1 (en) * 2009-04-28 2010-11-04 Wyeth Llc Parasiticidal combinations of macrocyclic lactones and polyether antibiotics
AU2014203209B2 (en) * 2009-07-31 2015-11-26 Boehringer Ingelheim Animal Health USA Inc. Sustained release capsules
ES2752923T3 (es) 2009-07-31 2020-04-06 Boehringer Ingelheim Animal Health Usa Inc Cápsulas de liberación prolongada
AU2010330844B2 (en) * 2009-12-17 2014-11-27 Boehringer Ingelheim Animal Health USA Inc. Compositions comprising macrocyclic lactone compounds and spirodioxepinoindoles
FR2992219B1 (fr) * 2012-06-22 2014-07-11 Aditec Lab Composition pour le traitement de l'hypocalcemie chez les ruminants
AU2015284078B2 (en) 2014-07-03 2020-01-30 SpecGx LLC Abuse deterrent immediate release formulations comprising non-cellulose polysaccharides
US11065246B2 (en) 2016-02-08 2021-07-20 SpecGx LLC Glucomannan containing pharmaceutical compositions with extended release and abuse deterrent properties
IL266377B2 (en) * 2016-12-02 2023-10-01 Clexio Biosciences Ltd Stomach retention system
UY37780A (es) * 2017-06-26 2019-01-31 Merial Inc Composiciones de gránulos parasiticidas con doble principio activo, sus métodos y usos
CA189879S (en) * 2017-08-25 2021-02-18 Argenta Mfg Limited Cap for an intraruminal device
US20220054809A1 (en) * 2018-09-10 2022-02-24 Argenta Innovation Limited Controlled release formulations in delivery devices
WO2020055270A1 (en) * 2018-09-10 2020-03-19 Argenta Innovation Limited Sustained release formulations in delivery devices
EP3856160A4 (en) 2018-09-25 2022-07-06 SpecGx LLC ANTI-ABUSE IMMEDIATE RELEASE CAPSULES DOSAGE FORMS
PL4013348T3 (pl) * 2019-08-14 2024-07-08 Elanco Tiergesundheit Ag Nowy ochraniacz skrzydełek do oskrzydlonej kapsułki i sposób jego stosowania
MX2022009689A (es) * 2020-02-07 2022-11-08 Elanco Animal Health Incorporated Cápsula alada.
WO2021242481A1 (en) * 2020-05-28 2021-12-02 Boehringer Ingelheim Animal Health USA Inc. Bi-modal release intra-ruminal capsule device and methods of use thereof
JP2023553202A (ja) 2020-12-08 2023-12-20 ルミナント バイオテク コーポレーション リミテッド 動物に物質を送達するための装置および方法の改善
CN113398337A (zh) * 2021-06-23 2021-09-17 上海市肺科医院 包含抗结核药物缓释植入人工骨载体的脊柱内固定装置

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU520409B2 (en) * 1977-05-25 1982-01-28 Commonwealth Scientific And Industrial Research Organisation Controlled release composition
GB2077586A (en) * 1980-06-12 1981-12-23 Standard Telephones Cables Ltd Sustained-release device
NZ197543A (en) * 1980-07-02 1984-12-14 Commw Scient Ind Res Org Controlled release compositions for inclusion in intraruminal devices
US4416659A (en) * 1981-11-09 1983-11-22 Eli Lilly And Company Sustained release capsule for ruminants
NZ203203A (en) * 1982-02-16 1985-09-13 Commw Scient Ind Res Org Controlled release device:gas diffusion limited
IE54171B1 (en) * 1982-06-22 1989-07-05 Univ Glasgow Device for introducing nutrients and/or therapeutic materials into ruminant animals
GB8328916D0 (en) * 1983-10-28 1983-11-30 Castex Prod Pharmaceutical pellet
US4777049A (en) * 1983-12-01 1988-10-11 Alza Corporation Constant release system with pulsed release
NZ212100A (en) * 1984-06-02 1988-07-28 Castex Prod Rumen bolus; outer casing sheds in segments
US4723958A (en) * 1986-05-23 1988-02-09 Merck & Co., Inc. Pulsatile drug delivery system
US4867980A (en) * 1986-10-10 1989-09-19 Coopers Animal Health Australia Limited Heavy density depot
US5391381A (en) * 1987-06-25 1995-02-21 Alza Corporation Dispenser capable of delivering plurality of drug units
US5938654A (en) * 1987-06-25 1999-08-17 Alza Corporation Osmotic device for delayed delivery of agent
US4957494A (en) * 1987-06-25 1990-09-18 Alza Corporation Multi-layer delivery system
US5023088A (en) * 1987-06-25 1991-06-11 Alza Corporation Multi-unit delivery system
US4874388A (en) * 1987-06-25 1989-10-17 Alza Corporation Multi-layer delivery system
US5110597A (en) * 1987-06-25 1992-05-05 Alza Corporation Multi-unit delivery system
US4915949A (en) * 1987-07-13 1990-04-10 Alza Corporation Dispenser with movable matrix comprising a plurality of tiny pills
GB8829089D0 (en) * 1988-12-13 1989-01-25 Coopers Animal Health Intra ruminal device
ES2044246T3 (es) * 1989-02-11 1994-01-01 Bayer Ag Medicamentos con liberacion controlada del producto activo.
US5110598A (en) * 1989-06-30 1992-05-05 Smithkline Beecham Corp. Intermittent release dosage form
US5126142A (en) * 1989-07-18 1992-06-30 Alza Corporation Dispenser comprising ionophore
US5017381A (en) * 1990-05-02 1991-05-21 Alza Corporation Multi-unit pulsatile delivery system
MX9200339A (es) * 1991-01-28 1992-08-01 Hoechst Ag Preparado para la liberacion controlada de sustancias activas, que son apropiadas como terapeuticos o para mejorar el crecimiento y el aprovechamiento de los piensos en rumiantes
US5417682A (en) * 1991-01-30 1995-05-23 Alza Corporation Device for administering active agent to biological environment
AU650113B2 (en) * 1991-04-05 1994-06-09 Eli Lilly And Company Sustained release capsule and formulations
US5240713A (en) * 1991-09-27 1993-08-31 Alza Corporation Dual rate agent delivery device
US5221278A (en) * 1992-03-12 1993-06-22 Alza Corporation Osmotically driven delivery device with expandable orifice for pulsatile delivery effect
AU697144B2 (en) * 1994-01-20 1998-10-01 Agresearch Limited Device for administration of beneficial materials to ruminants
AUPM897594A0 (en) * 1994-10-25 1994-11-17 Daratech Pty Ltd Controlled release container
CA2653839A1 (en) * 1998-11-02 2000-05-11 John G. Devane Multiparticulate modified release composition
US6569857B1 (en) * 1999-05-03 2003-05-27 Drugtech Corporation Dietary supplement
DE19956486A1 (de) * 1999-11-24 2001-06-21 Lohmann Therapie Syst Lts Mehrschichtige Zubereitung zur gesteuerten, pulsartigen Abgabe von Wirkstoffen
WO2001049311A1 (en) * 1999-12-31 2001-07-12 Rutgers, The State University Pharmaceutical formulation composed of a polymer blend and an active compound for time-controlled release
WO2001064191A1 (de) * 2000-02-28 2001-09-07 Akzo Nobel N.V. Körper für die kontrollierte abgabe von wirkstoffen

Also Published As

Publication number Publication date
EP1448151A1 (en) 2004-08-25
AUPR839001A0 (en) 2001-11-15
AU2004210542B2 (en) 2005-07-28
PE20030519A1 (es) 2003-06-13
HUP0401808A2 (hu) 2005-01-28
NZ531672A (en) 2006-08-31
AU2002332975B2 (en) 2005-02-03
CN1571663A (zh) 2005-01-26
AU2005227413A1 (en) 2005-11-17
AU2004210542B9 (en) 2005-09-01
AU2004210542A1 (en) 2004-09-30
EA005778B1 (ru) 2005-06-30
EA200400557A1 (ru) 2005-02-24
KR20050037410A (ko) 2005-04-21
MXPA04003679A (es) 2004-07-23
US20050064032A1 (en) 2005-03-24
IL160754A0 (en) 2004-08-31
WO2003033031A1 (en) 2003-04-24
PL368387A1 (en) 2005-03-21
BR0212975A (pt) 2004-10-13
ZA200403743B (en) 2005-05-16
HRP20040231A2 (en) 2004-08-31
AU2002332975C1 (en) 2009-01-29
NO20041941L (no) 2004-05-10
HUP0401808A3 (en) 2005-11-28
AU2009250987A1 (en) 2010-01-14
CA2463674A1 (en) 2003-04-24
AR037116A1 (es) 2004-10-20
JP2005510485A (ja) 2005-04-21
EP1448151A4 (en) 2010-01-13
CR7312A (es) 2004-10-27
AU2002332975B9 (en) 2005-03-17
AU2004210542C1 (en) 2009-01-08

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