ECSP045012A - 17alfa-hidroxi-14beta-esteroides con efecto hormonal - Google Patents

17alfa-hidroxi-14beta-esteroides con efecto hormonal

Info

Publication number
ECSP045012A
ECSP045012A EC2004005012A ECSP045012A ECSP045012A EC SP045012 A ECSP045012 A EC SP045012A EC 2004005012 A EC2004005012 A EC 2004005012A EC SP045012 A ECSP045012 A EC SP045012A EC SP045012 A ECSP045012 A EC SP045012A
Authority
EC
Ecuador
Prior art keywords
17alfa
14beta
hydroxi
steroids
hormonal effect
Prior art date
Application number
EC2004005012A
Other languages
English (en)
Inventor
Der Louw Jaap Van
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8180920&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP045012(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of ECSP045012A publication Critical patent/ECSP045012A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0062—Estrane derivatives substituted in position 17 alfa not substituted in position 17 beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se refiere a compuestos esteroidales de la fórmula (I), en donde R1 es O, (H,H), (H,OH), NOH, de los cuales OH puede ser opcionalmente eterificado o esterificado; R2 y R3 son independientemente hidrógeno o (C1-4)alquilo y por lo menos uno de R2 y R3 es (C1-4)alquilo; R4 es hidrógeno o (C1-15)acilo para uso en tratamientos relacionados con andrógenos, tales como la insuficiencia de andrógenos y la anticoncepción masculina o femenina.
EC2004005012A 2001-09-12 2004-03-10 17alfa-hidroxi-14beta-esteroides con efecto hormonal ECSP045012A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01203455 2001-09-12

Publications (1)

Publication Number Publication Date
ECSP045012A true ECSP045012A (es) 2004-09-27

Family

ID=8180920

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2004005012A ECSP045012A (es) 2001-09-12 2004-03-10 17alfa-hidroxi-14beta-esteroides con efecto hormonal

Country Status (29)

Country Link
US (1) US7169769B2 (es)
EP (1) EP1427748B1 (es)
JP (1) JP4471653B2 (es)
KR (1) KR100940054B1 (es)
CN (1) CN1257913C (es)
AR (1) AR036462A1 (es)
AT (1) ATE395352T1 (es)
AU (1) AU2002339536B2 (es)
BR (1) BR0212409A (es)
CA (1) CA2505575C (es)
CY (1) CY1108152T1 (es)
DE (1) DE60226623D1 (es)
DK (1) DK1427748T3 (es)
EC (1) ECSP045012A (es)
ES (1) ES2305306T3 (es)
HK (1) HK1063637A1 (es)
HR (1) HRP20040193A2 (es)
HU (1) HUP0402139A3 (es)
IL (2) IL160451A0 (es)
IS (1) IS2555B (es)
MX (1) MXPA04002418A (es)
NO (1) NO326624B1 (es)
NZ (1) NZ531487A (es)
PL (1) PL207493B1 (es)
PT (1) PT1427748E (es)
RU (1) RU2294332C2 (es)
TW (1) TWI221154B (es)
WO (1) WO2003022864A1 (es)
ZA (1) ZA200401992B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI221154B (en) 2001-09-12 2004-09-21 Akzo Nobel Nv 17alpha-hydroxy-14beta-steroids with hormonal effect

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3338925A (en) * 1965-10-25 1967-08-29 Syntex Corp 17-substituted 14beta-estr-4-enes
WO2000053619A1 (en) * 1999-03-08 2000-09-14 Akzo Nobel N.V. 14.beta., 17-alpha-hydroxymethylandrostane derivatives as androgens
WO2001064227A2 (en) * 2000-02-29 2001-09-07 The National University Of Singapore Androgenic activity of eucommia ulmoides extracts
US6391868B2 (en) * 2000-05-10 2002-05-21 Lpt Research, Inc. Use of 5-alpha-androst-1-en-3,17-dione to increase the level of the anabolic/androgenic hormone 17-beta-hydroxy-5-alpha-androst-1-en-3-one in humans
TWI221154B (en) 2001-09-12 2004-09-21 Akzo Nobel Nv 17alpha-hydroxy-14beta-steroids with hormonal effect

Also Published As

Publication number Publication date
EP1427748B1 (en) 2008-05-14
BR0212409A (pt) 2004-08-03
ES2305306T3 (es) 2008-11-01
AR036462A1 (es) 2004-09-08
HK1063637A1 (en) 2005-01-07
ATE395352T1 (de) 2008-05-15
IL160451A (en) 2009-11-18
PL207493B1 (pl) 2010-12-31
CA2505575A1 (en) 2003-03-20
US20040259849A1 (en) 2004-12-23
WO2003022864A1 (en) 2003-03-20
NO20041010L (no) 2004-03-10
RU2004110934A (ru) 2005-08-20
TWI221154B (en) 2004-09-21
HUP0402139A3 (en) 2012-12-28
CA2505575C (en) 2010-01-26
JP2005505566A (ja) 2005-02-24
JP4471653B2 (ja) 2010-06-02
PT1427748E (pt) 2008-08-27
DK1427748T3 (da) 2008-09-08
NZ531487A (en) 2005-08-26
IL160451A0 (en) 2004-07-25
US7169769B2 (en) 2007-01-30
ZA200401992B (en) 2005-04-21
CN1257913C (zh) 2006-05-31
HRP20040193A2 (en) 2004-08-31
RU2294332C2 (ru) 2007-02-27
KR100940054B1 (ko) 2010-02-04
NO326624B1 (no) 2009-01-19
KR20040039346A (ko) 2004-05-10
HUP0402139A2 (hu) 2005-02-28
PL368727A1 (en) 2005-04-04
AU2002339536B2 (en) 2008-04-24
EP1427748A1 (en) 2004-06-16
IS7165A (is) 2004-02-26
MXPA04002418A (es) 2004-07-30
CN1553917A (zh) 2004-12-08
IS2555B (is) 2009-10-15
CY1108152T1 (el) 2014-02-12
DE60226623D1 (de) 2008-06-26

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