EA202192053A1 - Химерные промоторы для использования в метаболическом конструировании - Google Patents

Химерные промоторы для использования в метаболическом конструировании

Info

Publication number
EA202192053A1
EA202192053A1 EA202192053A EA202192053A EA202192053A1 EA 202192053 A1 EA202192053 A1 EA 202192053A1 EA 202192053 A EA202192053 A EA 202192053A EA 202192053 A EA202192053 A EA 202192053A EA 202192053 A1 EA202192053 A1 EA 202192053A1
Authority
EA
Eurasian Patent Office
Prior art keywords
chimeric
promotors
recombinant dna
dna fragment
metabolic design
Prior art date
Application number
EA202192053A
Other languages
English (en)
Inventor
Хайко Диц
Магдалена Мертель
Йорг Кларен
Александр Фарвик
Original Assignee
Клариант Продукте (Дойчланд) Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Клариант Продукте (Дойчланд) Гмбх filed Critical Клариант Продукте (Дойчланд) Гмбх
Publication of EA202192053A1 publication Critical patent/EA202192053A1/ru

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90Isomerases (5.)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00Technologies for the production of fuel of non-fossil origin
    • Y02E50/10Biofuels, e.g. bio-diesel

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Настоящее изобретение содержит химерный промотор, который инициирует транскрипцию гена в зависимости от различных условий, таких как источники углерода. Дополнительно, изобретение относится к фрагменту рекомбинантной ДНК, содержащей химерный промотор, экспрессирующей плазмиде, содержащей фрагмент рекомбинантной ДНК, и клетке-хозяину, трансформированной фрагментом рекомбинантной ДНК.
EA202192053A 2019-01-29 2020-01-13 Химерные промоторы для использования в метаболическом конструировании EA202192053A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP19154364.4A EP3690052B1 (en) 2019-01-29 2019-01-29 Chimeric promoter for use in metabolic engineering
PCT/EP2020/050726 WO2020156794A1 (en) 2019-01-29 2020-01-13 Chimeric promoter for use in metabolic engineering

Publications (1)

Publication Number Publication Date
EA202192053A1 true EA202192053A1 (ru) 2021-10-20

Family

ID=65243467

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202192053A EA202192053A1 (ru) 2019-01-29 2020-01-13 Химерные промоторы для использования в метаболическом конструировании

Country Status (17)

Country Link
US (1) US20230159941A1 (ru)
EP (2) EP3690052B1 (ru)
CN (1) CN113302306A (ru)
AR (1) AR117903A1 (ru)
AU (1) AU2020213619A1 (ru)
BR (1) BR112021014923A2 (ru)
CA (1) CA3122190A1 (ru)
DK (1) DK3690052T3 (ru)
EA (1) EA202192053A1 (ru)
ES (1) ES2948239T3 (ru)
FI (1) FI3690052T3 (ru)
HR (1) HRP20230560T1 (ru)
HU (1) HUE062297T2 (ru)
MY (1) MY196151A (ru)
PL (1) PL3690052T3 (ru)
RS (1) RS64248B1 (ru)
WO (1) WO2020156794A1 (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023094429A1 (en) * 2021-11-23 2023-06-01 Kaesler Nutrition Gmbh Artificial yeast promoter regions

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646012A (en) * 1991-04-30 1997-07-08 Rhone-Poulenc Rorer S.A. Yeast promoter and use thereof
FR2676070B1 (fr) * 1991-04-30 1994-09-30 Rhone Poulenc Rorer Sa Promoteur de levure et son utilisation.
US20120003695A1 (en) * 2009-02-25 2012-01-05 Davidson Robert C Metabolic engineering of a galactose assimilation pathway in the glycoengineered yeast pichia pastoris
WO2012045088A2 (en) * 2010-10-01 2012-04-05 The Board Of Trustees Of The University Of Illinois Combinatorial design of highly efficient heterologous pathways
ES2913825T3 (es) * 2011-10-07 2022-06-06 Lonza Ag Promotor regulable
CN104284980A (zh) * 2011-12-30 2015-01-14 布特马斯先进生物燃料有限责任公司 用于丁醇生产的基因开关
CA3109156C (en) * 2014-05-16 2023-08-15 Academia Sinica Recombinant polynucleotide sequence for producing astaxanthin and uses thereof
EP2993230A1 (en) * 2014-09-02 2016-03-09 Clariant Produkte (Deutschland) GmbH Polypeptides having xylanase activity with a high conversion rate of xylose-containing polysaccharides
DK3209677T3 (da) * 2014-10-22 2020-08-03 Lallemand Hungary Liquidity Man Llc Varianter af gal2-transporter og anvendelser deraf
PL3026116T3 (pl) * 2014-11-26 2017-09-29 Clariant International Ltd Sekwencja oligonukleotydowa do stosowania w modyfikacji szlaku
EP3242949B1 (en) * 2015-01-06 2021-11-03 DSM IP Assets B.V. A crispr-cas system for a yeast host cell
US9506097B1 (en) * 2015-07-10 2016-11-29 The United States Of America, As Represented By The Secretary Of Agriculture Synthetic promoter for xylose-regulated gene expression
CN108350447B (zh) * 2015-08-05 2021-08-31 龙沙有限公司 启动子变体

Also Published As

Publication number Publication date
DK3690052T3 (da) 2023-06-19
WO2020156794A1 (en) 2020-08-06
CN113302306A (zh) 2021-08-24
EP3690052A1 (en) 2020-08-05
ES2948239T3 (es) 2023-09-06
MY196151A (en) 2023-03-17
BR112021014923A2 (pt) 2021-09-28
HRP20230560T1 (hr) 2023-08-18
AR117903A1 (es) 2021-09-01
US20230159941A1 (en) 2023-05-25
EP3918079A1 (en) 2021-12-08
PL3690052T3 (pl) 2023-08-14
EP3690052B1 (en) 2023-04-19
AU2020213619A1 (en) 2021-06-17
FI3690052T3 (fi) 2023-06-19
RS64248B1 (sr) 2023-06-30
CA3122190A1 (en) 2020-08-06
HUE062297T2 (hu) 2023-10-28

Similar Documents

Publication Publication Date Title
PH12017501942A1 (en) Oncolytic adenovirus encoding a b7 protein
MY202029A (en) T-cell modulatory multimeric polypeptides and methods of use thereof
MX2018012376A (es) Sistemas de replicón de arterivirus recombinantes y usos de estos.
MX2016010649A (es) Vector de virus adeno-asociado.
MY187559A (en) Modified hepatitis post-transcriptional regulatory elements
MX2020005282A (es) Vector para la produccion de particulas aav.
PE20090125A1 (es) Un microorganismo que produce un amino acido de la familia de acidos l-glutamico y el metodo que permite producir el amino acido
MX2018007485A (es) Variantes de enzimas y polinucleotidos que las codifican.
MX2019009316A (es) Promotor corto y potente para la expresion de genes heterologos.
PH12020551134A1 (en) Fc variants with enhanced binding to fcrn and prolonged half-life
BR112012016808A2 (pt) cepa hospedeira bacteriana expressando dsbc recombinante e tendo atividade tsp reduzida
IN2014DN10111A (ru)
BR112018001121A2 (pt) vetor recombinante do vírus orf (orfv), célula, composição, uso de um vetor recombinante de orfv, e, molécula de ácido nucleico
MX2017001824A (es) Mutaciones en proteinas del grupo hierro-azufre que mejoran la utilizacion de xilosa.
EA202192053A1 (ru) Химерные промоторы для использования в метаболическом конструировании
BR112021012240A2 (pt) Terapia de gene-célula-tronco hematopoiética para síndrome wiskott-aldrich
MY195997A (en) Recombinant Gene
MX2021009154A (es) Selectividad eficaz de proteinas recombinantes.
EA201791156A1 (ru) Последовательности олигонуклеотидов для применения в конструировании путей
WO2018013705A8 (en) Use of glucocorticoid analogs to enhance recombinant adeno-associated virus yield
PH12017500430A1 (en) Solubilized enzyme and uses thereof
MX2021008649A (es) Peptido alfa de la beta-galactosidasa como marcador de seleccion no antibiotico y usos de este.
EA201991797A1 (ru) Высокоактивный и короткий промотор, предназначенный для экспрессии гетерологичных генов
RU2012116425A (ru) РЕКОМБИНАНТНАЯ ДНК, КОДИРУЮЩАЯ ЛИЗОСТАФИН (LSS), И РЕКОМБИНАНТНАЯ ПЛАЗМИДА pLS26, ОБЕСПЕЧИВАЮЩАЯ СИНТЕЗ LSS В КЛЕТКАХ Escherichiacoli
Kmiecik et al. Erratum to: One-Dimensional Structural Properties of Proteins in the Coarse-Grained CABS Model