EA202092832A1 - Полимеры на основе бифункциональных модифицированных биополимеров и гидрогели, получаемые из таких полимеров на основе бифункциональных модифицированных биополимеров - Google Patents

Полимеры на основе бифункциональных модифицированных биополимеров и гидрогели, получаемые из таких полимеров на основе бифункциональных модифицированных биополимеров

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Publication number
EA202092832A1
EA202092832A1 EA202092832A EA202092832A EA202092832A1 EA 202092832 A1 EA202092832 A1 EA 202092832A1 EA 202092832 A EA202092832 A EA 202092832A EA 202092832 A EA202092832 A EA 202092832A EA 202092832 A1 EA202092832 A1 EA 202092832A1
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EA
Eurasian Patent Office
Prior art keywords
bifunctional modified
polymers based
bifunctional
modified biopolymers
functional groups
Prior art date
Application number
EA202092832A
Other languages
English (en)
Inventor
Яспер Ван Хорик
Сандра Ван Влирбергхе
Original Assignee
Университейт Гент
Врейе Университейт Брюссель
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Application filed by Университейт Гент, Врейе Университейт Брюссель filed Critical Университейт Гент
Publication of EA202092832A1 publication Critical patent/EA202092832A1/ru

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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00—Macromolecular products derived from proteins
    • C08H1/06—Macromolecular products derived from proteins derived from horn, hoofs, hair, skin or leather
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028—Polypeptides; Proteins; Degradation products thereof
    • A61L26/0033—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028—Polypeptides; Proteins; Degradation products thereof
    • A61L26/0038—Gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/008—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/222—Gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
    • C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
    • C08J3/075—Macromolecular gels
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
    • C08L89/04—Products derived from waste materials, e.g. horn, hoof or hair
    • C08L89/06—Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin, e.g. gelatin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2389/00—Characterised by the use of proteins; Derivatives thereof
    • C08J2389/04—Products derived from waste materials, e.g. horn, hoof or hair
    • C08J2389/06—Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Materials Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Materials For Medical Uses (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Macromonomer-Based Addition Polymer (AREA)

Abstract

Настоящее изобретение относится к полимеру на основе бифункционального модифицированного биополимера, содержащему по меньшей мере одну полимерную цепь, содержащую n функциональных групп первого типа и m функциональных групп второго типа. Функциональные группы первого типа включают группы, способные к сшиванию по радикальному механизму после свободнорадикальной полимеризации с ростом цепи. Функциональные группы второго типа включают группы, способные к тиоленовому сшиванию. Предпочтительные полимеры на основе бифункциональных модифицированных биополимеров включают бифункциональный модифицированный желатин и бифункциональный модифицированный коллаген. Настоящее изобретение дополнительно относится к способу получения такого полимера на основе бифункционального модифицированного биополимера и к способу получения гидрогеля из такого полимера на основе бифункционального модифицированного биополимера. Кроме того, настоящее изобретение относится к гидрогелям, получаемым из таких полимеров на основе бифункциональных модифицированных биополимеров, и к применению таких гидрогелей.
EA202092832A 2018-05-31 2019-05-29 Полимеры на основе бифункциональных модифицированных биополимеров и гидрогели, получаемые из таких полимеров на основе бифункциональных модифицированных биополимеров EA202092832A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18175368 2018-05-31
PCT/EP2019/063995 WO2019229140A1 (en) 2018-05-31 2019-05-29 Bifunctional modified biopolymer based polymers and hydrogels obtainable from such bifunctional modified biopolymer based polymers

Publications (1)

Publication Number Publication Date
EA202092832A1 true EA202092832A1 (ru) 2021-03-01

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EA202092832A EA202092832A1 (ru) 2018-05-31 2019-05-29 Полимеры на основе бифункциональных модифицированных биополимеров и гидрогели, получаемые из таких полимеров на основе бифункциональных модифицированных биополимеров

Country Status (10)

Country Link
US (1) US20210198433A1 (ru)
EP (1) EP3802703A1 (ru)
JP (1) JP7204154B2 (ru)
KR (2) KR102592759B1 (ru)
CN (1) CN112543791B (ru)
AU (2) AU2019276160B2 (ru)
BR (1) BR112020024128A2 (ru)
CA (1) CA3101402C (ru)
EA (1) EA202092832A1 (ru)
WO (1) WO2019229140A1 (ru)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3185350A1 (en) * 2020-06-19 2021-12-23 Universiteit Gent Swellable gelatin compositions
CN111743857A (zh) * 2020-07-30 2020-10-09 瑞希(重庆)生物科技有限公司 一种壳聚糖水凝胶及其制备方法

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WO2003031483A1 (en) * 2001-10-10 2003-04-17 The Regents Of The University Of Colorado Degradable thiol-ene polymers
EP1796602A4 (en) * 2004-09-17 2016-10-19 Angiotech Pharm Inc MULTIFUNCTIONAL COMPOUNDS FOR PRODUCING NETWORKED BIOMATERIALS AND MANUFACTURING AND USE METHOD THEREFOR
ITMI20061726A1 (it) * 2006-09-11 2008-03-12 Fidia Farmaceutici Derivati crosslinkati a base di acido ialuronico reticolato via click chemistry
KR20100125187A (ko) * 2009-05-20 2010-11-30 히다치 가세고교 가부시끼가이샤 카르복실기 함유 (메타)아크릴산에스테르 및 그 제조방법
WO2011088213A1 (en) * 2010-01-15 2011-07-21 University Of Utah Research Foundation Crosslinked hydrogels and methods of making and using thereof
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US20210198433A1 (en) 2021-07-01
CN112543791B (zh) 2023-06-30
EP3802703A1 (en) 2021-04-14
AU2019276160A1 (en) 2021-01-14
JP2021525305A (ja) 2021-09-24
AU2022211848B2 (en) 2024-05-30
JP7204154B2 (ja) 2023-01-16
WO2019229140A1 (en) 2019-12-05
CN112543791A (zh) 2021-03-23
CA3101402A1 (en) 2019-12-05
CA3101402C (en) 2023-09-12
AU2019276160B2 (en) 2022-08-18
BR112020024128A2 (pt) 2021-02-17
KR102592759B1 (ko) 2023-10-20
KR20210030903A (ko) 2021-03-18
AU2022211848A1 (en) 2022-08-25
KR20230013155A (ko) 2023-01-26

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