EA202092305A1 - Соединения в качестве модуляторов сигнализации tlr2 - Google Patents

Соединения в качестве модуляторов сигнализации tlr2

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Publication number
EA202092305A1
EA202092305A1 EA202092305A EA202092305A EA202092305A1 EA 202092305 A1 EA202092305 A1 EA 202092305A1 EA 202092305 A EA202092305 A EA 202092305A EA 202092305 A EA202092305 A EA 202092305A EA 202092305 A1 EA202092305 A1 EA 202092305A1
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EA
Eurasian Patent Office
Prior art keywords
tlr2
modulators
alarm
connections
compounds
Prior art date
Application number
EA202092305A
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English (en)
Inventor
Сриниваса Редди Натала
Вольфганг Вразидло
Original Assignee
Нейропор Терапиз, Инк.
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Application filed by Нейропор Терапиз, Инк. filed Critical Нейропор Терапиз, Инк.
Publication of EA202092305A1 publication Critical patent/EA202092305A1/ru

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    • C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/11—Aldehydes
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
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    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Abstract

Настоящее изобретение относится к соединениям, фармацевтическим композициям, содержащим такие соединения, и к применению таких соединений в способах лечения или в лекарственных средствах для лечения воспалительных заболеваний и определенных неврологических расстройств, которые связаны с воспалительными сигнальными процессами, включая без ограничения неправильно свернутые белки.
EA202092305A 2018-03-27 2019-03-27 Соединения в качестве модуляторов сигнализации tlr2 EA202092305A1 (ru)

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AU2019242734A1 (en) 2020-09-24
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