EA201892490A1 - Пцр с мультиплексной оптимизированной амплификацией неправильно спаренных оснований (moma) в реальном времени для анализа состояния плода - Google Patents
Пцр с мультиплексной оптимизированной амплификацией неправильно спаренных оснований (moma) в реальном времени для анализа состояния плодаInfo
- Publication number
- EA201892490A1 EA201892490A1 EA201892490A EA201892490A EA201892490A1 EA 201892490 A1 EA201892490 A1 EA 201892490A1 EA 201892490 A EA201892490 A EA 201892490A EA 201892490 A EA201892490 A EA 201892490A EA 201892490 A1 EA201892490 A1 EA 201892490A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- moma
- multiplex
- pcr
- analysis
- real time
- Prior art date
Links
- 241000840267 Moma Species 0.000 title 1
- 230000003321 amplification Effects 0.000 title 1
- 238000004458 analytical method Methods 0.000 title 1
- 230000001605 fetal effect Effects 0.000 title 1
- 238000003199 nucleic acid amplification method Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 210000003754 fetus Anatomy 0.000 abstract 1
- 210000001161 mammalian embryo Anatomy 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6858—Allele-specific amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Computational Biology (AREA)
- Evolutionary Biology (AREA)
- Medical Informatics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Theoretical Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662330044P | 2016-04-29 | 2016-04-29 | |
| PCT/US2017/030292 WO2017190105A1 (en) | 2016-04-29 | 2017-04-29 | Multiplexed optimized mismatch amplification (moma)-real time pcr for assessing fetal well being |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA201892490A1 true EA201892490A1 (ru) | 2019-07-31 |
Family
ID=60161136
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201892490A EA201892490A1 (ru) | 2016-04-29 | 2017-04-29 | Пцр с мультиплексной оптимизированной амплификацией неправильно спаренных оснований (moma) в реальном времени для анализа состояния плода |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20190153525A1 (https=) |
| EP (1) | EP3449018A4 (https=) |
| JP (1) | JP2019514387A (https=) |
| CN (1) | CN109661476A (https=) |
| AU (1) | AU2017258800A1 (https=) |
| BR (1) | BR112018072197A2 (https=) |
| CA (1) | CA3022548A1 (https=) |
| EA (1) | EA201892490A1 (https=) |
| IL (1) | IL262641A (https=) |
| MX (1) | MX2018013261A (https=) |
| WO (1) | WO2017190105A1 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11111543B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US9424392B2 (en) | 2005-11-26 | 2016-08-23 | Natera, Inc. | System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals |
| US11322224B2 (en) | 2010-05-18 | 2022-05-03 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US20190010543A1 (en) | 2010-05-18 | 2019-01-10 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11939634B2 (en) | 2010-05-18 | 2024-03-26 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US10316362B2 (en) | 2010-05-18 | 2019-06-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US12221653B2 (en) | 2010-05-18 | 2025-02-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US9677118B2 (en) | 2014-04-21 | 2017-06-13 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US12152275B2 (en) | 2010-05-18 | 2024-11-26 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| AU2011358564B9 (en) | 2011-02-09 | 2017-07-13 | Natera, Inc | Methods for non-invasive prenatal ploidy calling |
| US20140100126A1 (en) | 2012-08-17 | 2014-04-10 | Natera, Inc. | Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data |
| US20180173845A1 (en) | 2014-06-05 | 2018-06-21 | Natera, Inc. | Systems and Methods for Detection of Aneuploidy |
| WO2016183106A1 (en) | 2015-05-11 | 2016-11-17 | Natera, Inc. | Methods and compositions for determining ploidy |
| WO2017181202A2 (en) | 2016-04-15 | 2017-10-19 | Natera, Inc. | Methods for lung cancer detection |
| GB201618485D0 (en) | 2016-11-02 | 2016-12-14 | Ucl Business Plc | Method of detecting tumour recurrence |
| CN110114477A (zh) * | 2016-11-02 | 2019-08-09 | 威斯康星州立大学医学院 | 用于使用总的和特异性无细胞dna评估风险的方法 |
| CA3042722A1 (en) * | 2016-11-02 | 2018-05-11 | The Medical College Of Wisconsin, Inc. | Methods for assessing risk using mismatch amplification and statistical methods |
| AU2018288832B2 (en) | 2017-06-20 | 2025-03-06 | The Medical College Of Wisconsin, Inc. | Assessing transplant complication risk with total cell-free DNA |
| JP2021506342A (ja) | 2017-12-14 | 2021-02-22 | ティーエーアイ ダイアグノスティックス インコーポレイテッドＴａｉ Ｄｉａｇｎｏｓｔｉｃｓ，Ｉｎｃ． | 移植のための移植片適合性の評価 |
| CA3090426A1 (en) | 2018-04-14 | 2019-10-17 | Natera, Inc. | Methods for cancer detection and monitoring by means of personalized detection of circulating tumor dna |
| US12234509B2 (en) | 2018-07-03 | 2025-02-25 | Natera, Inc. | Methods for detection of donor-derived cell-free DNA |
| US11931674B2 (en) | 2019-04-04 | 2024-03-19 | Natera, Inc. | Materials and methods for processing blood samples |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004078999A1 (en) * | 2003-03-05 | 2004-09-16 | Genetic Technologies Limited | Identification of fetal dna and fetal cell markers in maternal plasma or serum |
| EP2351858B1 (en) * | 2006-02-28 | 2014-12-31 | University of Louisville Research Foundation | Detecting fetal chromosomal abnormalities using tandem single nucleotide polymorphisms |
| BR112014014664B1 (pt) * | 2011-12-16 | 2023-02-28 | Basf Agrochemical Products, B.V | Método para analisar um gene ahasl de planta e kit para analisar um gene ahasl de planta |
| WO2014143989A1 (en) * | 2013-03-15 | 2014-09-18 | Medical College Of Wisconsin, Inc. | Fetal well being surveillance using fetal specific cell free dna |
| WO2015178978A2 (en) * | 2014-02-14 | 2015-11-26 | The Board Of Regents Of The University Of Texas System | Strand exchange hairpin primers that give high allelic discrimination |
| US20180142296A1 (en) * | 2015-04-30 | 2018-05-24 | Medical College Of Wisconsin, Inc. | Multiplexed optimized mismatch amplification (moma)-real time pcr for assessing cell-free dna |
-
2017
- 2017-04-29 EP EP17790614.6A patent/EP3449018A4/en not_active Withdrawn
- 2017-04-29 BR BR112018072197A patent/BR112018072197A2/pt not_active IP Right Cessation
- 2017-04-29 US US16/097,422 patent/US20190153525A1/en not_active Abandoned
- 2017-04-29 WO PCT/US2017/030292 patent/WO2017190105A1/en not_active Ceased
- 2017-04-29 AU AU2017258800A patent/AU2017258800A1/en not_active Abandoned
- 2017-04-29 EA EA201892490A patent/EA201892490A1/ru unknown
- 2017-04-29 JP JP2018556973A patent/JP2019514387A/ja active Pending
- 2017-04-29 MX MX2018013261A patent/MX2018013261A/es unknown
- 2017-04-29 CN CN201780040662.3A patent/CN109661476A/zh active Pending
- 2017-04-29 CA CA3022548A patent/CA3022548A1/en not_active Abandoned
-
2018
- 2018-10-28 IL IL262641A patent/IL262641A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20190153525A1 (en) | 2019-05-23 |
| MX2018013261A (es) | 2019-04-22 |
| BR112018072197A2 (pt) | 2019-02-12 |
| CN109661476A (zh) | 2019-04-19 |
| AU2017258800A1 (en) | 2018-12-20 |
| CA3022548A1 (en) | 2017-11-02 |
| WO2017190105A1 (en) | 2017-11-02 |
| EP3449018A1 (en) | 2019-03-06 |
| EP3449018A4 (en) | 2019-11-06 |
| IL262641A (en) | 2018-12-31 |
| JP2019514387A (ja) | 2019-06-06 |
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