EA201890614A1 - Комбинированная антибактериальная композиция и короткий курс антибактериальной терапии - Google Patents

Комбинированная антибактериальная композиция и короткий курс антибактериальной терапии

Info

Publication number
EA201890614A1
EA201890614A1 EA201890614A EA201890614A EA201890614A1 EA 201890614 A1 EA201890614 A1 EA 201890614A1 EA 201890614 A EA201890614 A EA 201890614A EA 201890614 A EA201890614 A EA 201890614A EA 201890614 A1 EA201890614 A1 EA 201890614A1
Authority
EA
Eurasian Patent Office
Prior art keywords
antibacterial
combined
short course
therapy
composition
Prior art date
Application number
EA201890614A
Other languages
English (en)
Russian (ru)
Inventor
Кхисимузи Джр. Мдлули
Кэри М. Мэндел
Эрик Нюрмбергер
Original Assignee
Зе Глобал Эллайенс Фо Тб Драг Девелопмент, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=58518568&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201890614(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Зе Глобал Эллайенс Фо Тб Драг Девелопмент, Инк. filed Critical Зе Глобал Эллайенс Фо Тб Драг Девелопмент, Инк.
Publication of EA201890614A1 publication Critical patent/EA201890614A1/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965Non-condensed pyrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5365Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/227Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18Oxygen atoms
    • C07D263/20Oxygen atoms attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EA201890614A 2015-10-14 2016-10-05 Комбинированная антибактериальная композиция и короткий курс антибактериальной терапии EA201890614A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562241280P 2015-10-14 2015-10-14
PCT/US2016/055414 WO2017066053A1 (en) 2015-10-14 2016-10-05 Combination antibacterial composition and short-course antibacterial regimen

Publications (1)

Publication Number Publication Date
EA201890614A1 true EA201890614A1 (ru) 2019-02-28

Family

ID=58518568

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201890614A EA201890614A1 (ru) 2015-10-14 2016-10-05 Комбинированная антибактериальная композиция и короткий курс антибактериальной терапии

Country Status (15)

Country Link
US (3) US20180280401A1 (OSRAM)
EP (2) EP3362068B1 (OSRAM)
JP (5) JP6845233B2 (OSRAM)
KR (2) KR20240137128A (OSRAM)
CN (2) CN108495631A (OSRAM)
AU (3) AU2016338637A1 (OSRAM)
BR (1) BR112018007625A2 (OSRAM)
CA (1) CA3001309C (OSRAM)
EA (1) EA201890614A1 (OSRAM)
ES (1) ES2972618T3 (OSRAM)
HK (1) HK1254620A1 (OSRAM)
HR (1) HRP20240309T1 (OSRAM)
PL (1) PL3362068T3 (OSRAM)
WO (1) WO2017066053A1 (OSRAM)
ZA (1) ZA201802236B (OSRAM)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HK1254620A1 (zh) * 2015-10-14 2019-07-26 结核病药物开发全球联盟公司 联合抗菌组合物以及短疗程抗菌方案
RS65207B1 (sr) 2017-07-14 2024-03-29 Janssen Pharmaceutica Nv Formulacije bedakvilina sa dugim delovanjem
CN109387594B (zh) * 2017-08-08 2021-01-19 武汉武药科技有限公司 一种分离和分析贝达喹啉光学异构体的方法
WO2021016012A1 (en) * 2019-07-19 2021-01-28 The Global Alliance For Tb Drug Development, Inc. Pretomanid compositions
WO2021257461A1 (en) * 2020-06-15 2021-12-23 Mylan Laboratories Limited Combination antibacterial composition and method for antibacterial therapy
WO2021257466A1 (en) * 2020-06-15 2021-12-23 The Global Alliance For Tb Drug Development, Inc. Combination antibacterial composition and method for antibacterial therapy
GB202009684D0 (en) * 2020-06-26 2020-08-12 Viiv Healthcare Co Formulations
EP4271679A4 (en) * 2021-02-01 2024-09-11 The Global Alliance for TB Drug Development, Inc. AMORPHOUS FORM OF PRETOMANIDES
WO2025017047A1 (en) 2023-07-18 2025-01-23 Janssen Pharmaceutica Nv Combination products of at least three antibiotics comprising bedaquiline, pretomanid or delamanid, and a cytochrome bc1 inhibitor, and their use in the treatment of mycobacterial infections
CN117137918A (zh) * 2023-09-28 2023-12-01 深圳国家感染性疾病临床医学研究中心 一种药物组合物及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7889101B2 (en) * 2008-04-14 2011-02-15 Alpine Electronics, Inc Method and apparatus for generating location based reminder message for navigation system
NZ591169A (en) 2008-09-03 2012-12-21 Pfizer Combination therapy for tuberculosis
WO2011139832A2 (en) * 2010-04-28 2011-11-10 Rib-X Pharmaceuticals, Inc. Method for treating mycobacterial infections
HK1254620A1 (zh) 2015-10-14 2019-07-26 结核病药物开发全球联盟公司 联合抗菌组合物以及短疗程抗菌方案

Also Published As

Publication number Publication date
KR20180063318A (ko) 2018-06-11
CA3001309A1 (en) 2017-04-20
EP3362068B1 (en) 2023-12-20
CN108495631A (zh) 2018-09-04
US20200237770A1 (en) 2020-07-30
WO2017066053A1 (en) 2017-04-20
HRP20240309T1 (hr) 2024-05-10
JP7221922B2 (ja) 2023-02-14
EP4324824A2 (en) 2024-02-21
BR112018007625A2 (pt) 2018-10-30
KR102706436B1 (ko) 2024-09-12
US20180280401A1 (en) 2018-10-04
JP2024053045A (ja) 2024-04-12
ES2972618T3 (es) 2024-06-13
AU2021258039A1 (en) 2021-11-25
HK1254620A1 (zh) 2019-07-26
US20230414625A1 (en) 2023-12-28
ZA201802236B (en) 2022-07-27
CN114796231A (zh) 2022-07-29
EP4324824A3 (en) 2024-05-08
CA3001309C (en) 2023-12-19
EP3362068C0 (en) 2023-12-20
JP2021038257A (ja) 2021-03-11
EP3362068A4 (en) 2019-06-19
AU2021258039B2 (en) 2024-02-08
JP2018530578A (ja) 2018-10-18
AU2024203012B2 (en) 2025-07-10
KR20240137128A (ko) 2024-09-19
AU2024203012A1 (en) 2024-05-23
JP2024167369A (ja) 2024-12-03
AU2016338637A1 (en) 2018-04-26
PL3362068T3 (pl) 2024-06-24
JP6845233B2 (ja) 2021-03-17
JP2022082753A (ja) 2022-06-02
EP3362068A1 (en) 2018-08-22

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