EA201790696A1 - Способы и композиции для диагностики и прогнозирования повреждения почек и почечной недостаточности - Google Patents
Способы и композиции для диагностики и прогнозирования повреждения почек и почечной недостаточностиInfo
- Publication number
- EA201790696A1 EA201790696A1 EA201790696A EA201790696A EA201790696A1 EA 201790696 A1 EA201790696 A1 EA 201790696A1 EA 201790696 A EA201790696 A EA 201790696A EA 201790696 A EA201790696 A EA 201790696A EA 201790696 A1 EA201790696 A1 EA 201790696A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- kidney damage
- compositions
- methods
- prediction
- diagnosis
- Prior art date
Links
- 210000003734 kidney Anatomy 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 208000001647 Renal Insufficiency Diseases 0.000 title 1
- 238000003745 diagnosis Methods 0.000 title 1
- 201000006370 kidney failure Diseases 0.000 title 1
- 102000001902 CC Chemokines Human genes 0.000 abstract 1
- 108010040471 CC Chemokines Proteins 0.000 abstract 1
- 101150064697 CXCL16 gene Proteins 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 108010023337 axl receptor tyrosine kinase Proteins 0.000 abstract 1
- 239000000104 diagnostic biomarker Substances 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 239000000092 prognostic biomarker Substances 0.000 abstract 1
- 102000027426 receptor tyrosine kinases Human genes 0.000 abstract 1
- 238000011269 treatment regimen Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
- G01N2333/521—Chemokines
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/71—Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/34—Genitourinary disorders
- G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462066316P | 2014-10-20 | 2014-10-20 | |
| US201462066313P | 2014-10-20 | 2014-10-20 | |
| US201462066310P | 2014-10-20 | 2014-10-20 | |
| PCT/US2015/056462 WO2016064877A2 (en) | 2014-10-20 | 2015-10-20 | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA201790696A1 true EA201790696A1 (ru) | 2017-10-31 |
Family
ID=55761743
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201790696A EA201790696A1 (ru) | 2014-10-20 | 2015-10-20 | Способы и композиции для диагностики и прогнозирования повреждения почек и почечной недостаточности |
Country Status (13)
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA201790696A1 (ru) | 2014-10-20 | 2017-10-31 | Астьют Медикал, Инк. | Способы и композиции для диагностики и прогнозирования повреждения почек и почечной недостаточности |
| US11353465B2 (en) | 2017-01-12 | 2022-06-07 | Astute Medical, Inc. | Methods and compositions for evaluation and treatment of renal injury and renal failure based on C—C motif chemokine ligand 14 measurement |
| CN110431422A (zh) | 2017-02-06 | 2019-11-08 | 机敏医药股份有限公司 | 用于肾损伤和肾衰竭的诊断和预后的方法和组合物 |
| WO2019133902A2 (en) | 2017-12-28 | 2019-07-04 | Astute Medical, Inc. | Antibodies and assays for ccl14 |
| CA3094993A1 (en) * | 2018-04-02 | 2019-10-10 | Potrero Medical, Inc. | Systems, devices and methods for draining and analyzing bodily fluids and assessing health |
| US12114978B2 (en) | 2018-04-02 | 2024-10-15 | Potrero Medical, Inc. | Systems, devices and methods for draining and analyzing bodily fluids and assessing health |
| CN114207436A (zh) * | 2019-05-24 | 2022-03-18 | 机敏医药股份有限公司 | 基于c-c基序趋化因子配体14测量而评估和治疗肾损伤的方法 |
| US20230290457A1 (en) * | 2020-03-23 | 2023-09-14 | Biocogniv Inc. | Artificial intelligence medical device |
| GB2596142B (en) * | 2020-06-19 | 2023-11-29 | Secr Defence | Methods and associated uses, kits and systems for assessing sepsis |
| AU2021381364A1 (en) * | 2020-11-18 | 2023-06-22 | Astute Medical, Inc. | Methods and compositions for treatment of renal injury and renal failure |
| JP7902180B2 (ja) * | 2020-12-16 | 2026-08-07 | ジュノー セラピューティクス インコーポレイテッド | フローサイトメトリー方法のための閾値ゲーティング |
| EP4487114A4 (en) * | 2022-03-03 | 2026-03-25 | Astute Medical Inc | METHODS AND COMPOSITIONS FOR EVALUATING AND TREATING PERSISTENT ACUTE RENAL INJURY BASED ON A C-C MOTIFYING CHEMOKIN LIGAND MEASUREMENT 14 |
| JP2024039982A (ja) * | 2022-09-12 | 2024-03-25 | 栄研化学株式会社 | 急性腎障害の発症リスクの評価方法 |
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| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US5939272A (en) | 1989-01-10 | 1999-08-17 | Biosite Diagnostics Incorporated | Non-competitive threshold ligand-receptor assays |
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| US5922615A (en) | 1990-03-12 | 1999-07-13 | Biosite Diagnostics Incorporated | Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network |
| CA2072758A1 (en) | 1990-09-14 | 1992-03-15 | Kenneth Francis Buechler | Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays |
| US5955377A (en) | 1991-02-11 | 1999-09-21 | Biostar, Inc. | Methods and kits for the amplification of thin film based assays |
| AU1772992A (en) | 1991-04-10 | 1992-11-17 | Biosite Diagnostics Incorporated | Crosstalk inhibitors and their uses |
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| WO2007013919A2 (en) | 2005-07-21 | 2007-02-01 | The Johns Hopkins University | Methods of detecting and treating acute kidney injury |
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| EA201290195A1 (ru) * | 2009-11-07 | 2012-12-28 | Астьют Медикал, Инк. | Способы и композиции для диагностики и прогнозирования повреждений почек и почечной недостаточности |
| MX340078B (es) * | 2009-11-07 | 2016-06-24 | Astute Medical Inc | Metodos y composiciones para el diagnostico y pronostico de daño renal y falla renal. |
| US20120156701A1 (en) * | 2009-12-20 | 2012-06-21 | Joseph Anderberg | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| MX342967B (es) | 2009-12-20 | 2016-10-19 | Astute Medical Inc | Metodos y composiciones para la diagnosis y prognosis de lesion renal y falla renal. |
| CN102791885B (zh) * | 2010-02-05 | 2015-09-09 | 阿斯图特医药公司 | 用于肾损伤和肾衰竭的诊断及预后的方法和组合物 |
| NZ605698A (en) * | 2010-06-23 | 2015-03-27 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| IN2012MN02812A (cg-RX-API-DMAC10.html) * | 2010-06-23 | 2015-05-22 | Astute Medical Inc | |
| CN105137085A (zh) * | 2010-06-23 | 2015-12-09 | 阿斯图特医药公司 | 用于肾损伤和肾衰竭的诊断及预后的方法和组合物 |
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| CA2846602A1 (en) * | 2011-08-26 | 2013-03-28 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| EP3540440B1 (en) | 2011-12-08 | 2022-09-28 | Astute Medical, Inc. | Methods and uses for evaluating renal injury and renal status |
| WO2013096740A1 (en) * | 2011-12-21 | 2013-06-27 | Alere San Diego Inc. | Methods and compositions for assigning likelihood of chronic kidney disease progression |
| EP2962109A4 (en) | 2013-02-26 | 2016-12-07 | Astute Medical Inc | METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE |
| EA201790696A1 (ru) | 2014-10-20 | 2017-10-31 | Астьют Медикал, Инк. | Способы и композиции для диагностики и прогнозирования повреждения почек и почечной недостаточности |
-
2015
- 2015-10-20 EA EA201790696A patent/EA201790696A1/ru unknown
- 2015-10-20 EP EP15853584.9A patent/EP3210018B1/en active Active
- 2015-10-20 EP EP21186630.6A patent/EP3968022A1/en active Pending
- 2015-10-20 CN CN201580068922.9A patent/CN107003301B/zh active Active
- 2015-10-20 CN CN201910986041.5A patent/CN110702921B/zh active Active
- 2015-10-20 JP JP2017521231A patent/JP6792553B2/ja active Active
- 2015-10-20 KR KR1020177013539A patent/KR102431003B1/ko active Active
- 2015-10-20 PT PT15853584T patent/PT3210018T/pt unknown
- 2015-10-20 WO PCT/US2015/056462 patent/WO2016064877A2/en not_active Ceased
- 2015-10-20 MX MX2017005126A patent/MX388231B/es unknown
- 2015-10-20 US US15/520,817 patent/US11333671B2/en active Active
- 2015-10-20 AU AU2015336069A patent/AU2015336069B2/en active Active
- 2015-10-20 ES ES15853584T patent/ES2907551T3/es active Active
- 2015-10-20 CA CA2965153A patent/CA2965153C/en active Active
- 2015-10-20 BR BR112017008218A patent/BR112017008218A2/pt not_active Application Discontinuation
-
2020
- 2020-11-06 JP JP2020185705A patent/JP7002623B2/ja active Active
-
2021
- 2021-12-27 JP JP2021211779A patent/JP7217796B2/ja active Active
-
2022
- 2022-02-21 AU AU2022201130A patent/AU2022201130B2/en active Active
- 2022-03-31 US US17/710,832 patent/US12099067B2/en active Active
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2023
- 2023-01-24 JP JP2023008480A patent/JP2023052587A/ja active Pending
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