EA201790192A1 - СПОСОБ СНИЖЕНИЯ Fc-РЕЦЕПТОРНОГО СВЯЗЫВАНИЯ МОЛЕКУЛ СЫВОРОТОЧНОГО IgG У СУБЪЕКТА - Google Patents

СПОСОБ СНИЖЕНИЯ Fc-РЕЦЕПТОРНОГО СВЯЗЫВАНИЯ МОЛЕКУЛ СЫВОРОТОЧНОГО IgG У СУБЪЕКТА

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EA201790192A1
EA201790192A1 EA201790192A EA201790192A EA201790192A1 EA 201790192 A1 EA201790192 A1 EA 201790192A1 EA 201790192 A EA201790192 A EA 201790192A EA 201790192 A EA201790192 A EA 201790192A EA 201790192 A1 EA201790192 A1 EA 201790192A1
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subject
receptor binding
serum igg
igg molecules
reduce
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EA201790192A
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English (en)
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EA039169B1 (ru
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Кристиан Челльман
София Ярнум
Лена Винстедт
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Ханса Медикал Аб
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    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4873—Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H
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    • C12Y302/01096—Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase (3.2.1.96)
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Abstract

Данное изобретение относится к способу увеличения преимуществ терапии или терапевтического агента для субъекта. Данный способ включает введение субъекту агента, который снижает Fc-рецепторное связывание молекул сывороточного IgG у субъекта; и последующее проведение указанной терапии или введение указанного терапевтического агента субъекту. Данное изобретение также относится к способу уменьшения влияния патогенных аутоантител на субъекта, причем указанный способ включает (а) введение субъекту агента, который снижает Fc-рецепторное связывание молекул сывороточного IgG у субъекта, и, возможно, (b) последующее предоставление субъекту лечения, которое удаляет эндогенные аутоантитела. Данное изобретение также относится к набору для выполнения способа согласно данному изобретению.
EA201790192A 2014-07-25 2015-07-10 СПОСОБ СНИЖЕНИЯ Fc-РЕЦЕПТОРНОГО СВЯЗЫВАНИЯ МОЛЕКУЛ СЫВОРОТОЧНОГО IgG У СУБЪЕКТА EA039169B1 (ru)

Applications Claiming Priority (2)

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GBGB1413240.1A GB201413240D0 (en) 2014-07-25 2014-07-25 Method
PCT/EP2015/065895 WO2016012285A2 (en) 2014-07-25 2015-07-10 Method

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EA201790192A1 true EA201790192A1 (ru) 2017-09-29
EA039169B1 EA039169B1 (ru) 2021-12-13

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US (2) US10973889B2 (ru)
EP (1) EP3171891A2 (ru)
JP (1) JP6708641B2 (ru)
KR (2) KR20230119267A (ru)
CN (2) CN114949187A (ru)
AU (1) AU2015294125B2 (ru)
BR (1) BR112017001420A2 (ru)
CA (1) CA2955704A1 (ru)
CL (1) CL2017000191A1 (ru)
CO (1) CO2017000571A2 (ru)
EA (1) EA039169B1 (ru)
GB (1) GB201413240D0 (ru)
HK (1) HK1232122A1 (ru)
IL (1) IL249981B (ru)
MX (1) MX2017001138A (ru)
MY (1) MY196858A (ru)
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WO (1) WO2016012285A2 (ru)

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BR112017001420A2 (pt) 2017-11-28
CO2017000571A2 (es) 2017-06-20
IL249981A0 (en) 2017-03-30
CA2955704A1 (en) 2016-01-28
JP6708641B2 (ja) 2020-06-10
SG11201700172WA (en) 2017-02-27
WO2016012285A3 (en) 2016-04-14
JP2017522384A (ja) 2017-08-10
KR102565244B1 (ko) 2023-08-10
IL249981B (en) 2022-08-01
GB201413240D0 (en) 2014-09-10
EP3171891A2 (en) 2017-05-31
NZ728265A (en) 2024-03-22
CL2017000191A1 (es) 2017-08-25
CN114949187A (zh) 2022-08-30
AU2015294125B2 (en) 2020-10-15
HK1232122A1 (zh) 2018-01-05
WO2016012285A2 (en) 2016-01-28
MX2017001138A (es) 2017-06-07
AU2015294125A1 (en) 2017-02-02
MY196858A (en) 2023-05-05
CN106714834A (zh) 2017-05-24
US10973889B2 (en) 2021-04-13
US20210260173A1 (en) 2021-08-26
KR20170039243A (ko) 2017-04-10
KR20230119267A (ko) 2023-08-16
EA039169B1 (ru) 2021-12-13
US20170209550A1 (en) 2017-07-27

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