EA201592232A1 - Применение денцихина в получении лекарственного средства для лечения тромбоцитопении - Google Patents

Применение денцихина в получении лекарственного средства для лечения тромбоцитопении

Info

Publication number
EA201592232A1
EA201592232A1 EA201592232A EA201592232A EA201592232A1 EA 201592232 A1 EA201592232 A1 EA 201592232A1 EA 201592232 A EA201592232 A EA 201592232A EA 201592232 A EA201592232 A EA 201592232A EA 201592232 A1 EA201592232 A1 EA 201592232A1
Authority
EA
Eurasian Patent Office
Prior art keywords
treatment
thrombocytopenia
drugs
thrombocytopia
dentsikhin
Prior art date
Application number
EA201592232A
Other languages
English (en)
Inventor
Гуйхуа Лань
Фэн Лань
Сяобо Сунь
Original Assignee
Куньмин Шэнхо Фармасьютикал (Груп) Ко., Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Куньмин Шэнхо Фармасьютикал (Груп) Ко., Лтд. filed Critical Куньмин Шэнхо Фармасьютикал (Груп) Ко., Лтд.
Publication of EA201592232A1 publication Critical patent/EA201592232A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Раскрыты применения лекарственных средств для лечения тромбоцитопении, в особенности применение денцихина в получении лекарственных средств для лечения тромбоцитопении. Добавляя фармацевтически приемлемый обычный адъювантный материал, денцихин можно составить в пероральный препарат или препарат для инъекции. Фармакодинамические испытания показывают, что денцихин может эффективно ингибировать тромбоцитопению, вызванную препаратами для химиотерапии, и лечить тромбоцитопеническую пурпуру с очевидным лечебным эффектом и низкими токсическими побочными эффектами.
EA201592232A 2013-05-24 2013-05-24 Применение денцихина в получении лекарственного средства для лечения тромбоцитопении EA201592232A1 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2013/076216 WO2014186982A1 (zh) 2013-05-24 2013-05-24 三七素在制备治疗血小板减少症的药物的应用

Publications (1)

Publication Number Publication Date
EA201592232A1 true EA201592232A1 (ru) 2016-04-29

Family

ID=51932737

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201592232A EA201592232A1 (ru) 2013-05-24 2013-05-24 Применение денцихина в получении лекарственного средства для лечения тромбоцитопении

Country Status (7)

Country Link
US (1) US9526713B2 (ru)
EP (1) EP3006025A4 (ru)
JP (1) JP2016518455A (ru)
KR (1) KR20160012210A (ru)
BR (1) BR112015029280A2 (ru)
EA (1) EA201592232A1 (ru)
WO (1) WO2014186982A1 (ru)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5543044A (en) * 1978-09-23 1980-03-26 Takuo Kosuge Extraction of propionic acid derivative from panax notoginseng e.h. chen, and hemostatic agent and blood platelet increasing agent containing said derivative
JPS57114511A (en) * 1981-08-13 1982-07-16 Takuo Kosuge Hemostatic and platelet-increasing agent comprising propionic acid derivative
JPH06100462A (ja) * 1992-08-05 1994-04-12 Takeda Chem Ind Ltd 血小板増加剤
CN1064049C (zh) * 1995-10-05 2001-04-04 南京大学 血小板生成素制备工艺
CN1122659C (zh) * 2000-08-10 2003-10-01 昆明南国生物资源开发研究所 高效止血药三七素的合成制备方法
CN1292376A (zh) 2000-08-10 2001-04-25 昆明南国生物资源开发研究所 合成制备高效止血药三七素的方法
JP2003024076A (ja) * 2001-07-12 2003-01-28 Kirin Brewery Co Ltd Ｔｐｏ変異体タンパク質
TW200605906A (en) * 2004-05-11 2006-02-16 Chugai Pharmaceutical Co Ltd Remedy for thrombopenia
CN100579542C (zh) * 2007-08-24 2010-01-13 济南市第三人民医院 一种治疗血小板减少的中草药配方
US8362081B2 (en) * 2009-12-31 2013-01-29 Guihua Lan Methods for treating hemorrhagic conditions

Also Published As

Publication number Publication date
US20160089351A1 (en) 2016-03-31
BR112015029280A2 (pt) 2017-07-25
EP3006025A1 (en) 2016-04-13
US9526713B2 (en) 2016-12-27
EP3006025A4 (en) 2016-12-28
JP2016518455A (ja) 2016-06-23
WO2014186982A1 (zh) 2014-11-27
KR20160012210A (ko) 2016-02-02

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EA201592232A1 (ru) Применение денцихина в получении лекарственного средства для лечения тромбоцитопении