EA201591693A1 - Новые соединения, модулирующие контроль над дыханием, и способы их применения - Google Patents
Новые соединения, модулирующие контроль над дыханием, и способы их примененияInfo
- Publication number
- EA201591693A1 EA201591693A1 EA201591693A EA201591693A EA201591693A1 EA 201591693 A1 EA201591693 A1 EA 201591693A1 EA 201591693 A EA201591693 A EA 201591693A EA 201591693 A EA201591693 A EA 201591693A EA 201591693 A1 EA201591693 A1 EA 201591693A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- individual
- present
- methods
- application
- new connections
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 230000029058 respiratory gaseous exchange Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000000241 respiratory effect Effects 0.000 abstract 2
- 208000023504 respiratory system disease Diseases 0.000 abstract 2
- 230000001687 destabilization Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- JOZPEVMCAKXSEY-UHFFFAOYSA-N pyrimido[5,4-d]pyrimidine Chemical compound N1=CN=CC2=NC=NC=C21 JOZPEVMCAKXSEY-UHFFFAOYSA-N 0.000 abstract 1
- 230000033764 rhythmic process Effects 0.000 abstract 1
- 230000006641 stabilisation Effects 0.000 abstract 1
- 238000011105 stabilization Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/541—Non-condensed thiazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Otolaryngology (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361792185P | 2013-03-15 | 2013-03-15 | |
| PCT/US2014/025792 WO2014151462A1 (en) | 2013-03-15 | 2014-03-13 | Novel breathing control modulating compounds, and methods of using same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA201591693A1 true EA201591693A1 (ru) | 2016-03-31 |
Family
ID=51580966
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201591693A EA201591693A1 (ru) | 2013-03-15 | 2014-03-13 | Новые соединения, модулирующие контроль над дыханием, и способы их применения |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9643971B2 (enExample) |
| EP (1) | EP2968329A4 (enExample) |
| JP (1) | JP2016516714A (enExample) |
| KR (1) | KR20150143498A (enExample) |
| CN (1) | CN105209041A (enExample) |
| AU (1) | AU2014234095A1 (enExample) |
| BR (1) | BR112015023671A2 (enExample) |
| CA (1) | CA2905950A1 (enExample) |
| EA (1) | EA201591693A1 (enExample) |
| HK (1) | HK1219234A1 (enExample) |
| MX (1) | MX2015013137A (enExample) |
| SG (1) | SG11201507140PA (enExample) |
| WO (1) | WO2014151462A1 (enExample) |
| ZA (1) | ZA201507064B (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105340281B (zh) | 2013-07-05 | 2019-06-28 | 索尼公司 | 发送装置、发送方法、接收装置和接收方法 |
| NO346258B1 (en) * | 2015-06-30 | 2022-05-16 | Neurad Ltd | Novel breathing control modulating compounds, and methods of making and using same |
| US20210244742A1 (en) * | 2015-07-22 | 2021-08-12 | John Hsu | Composition comprising a therapeutic agent and a respiratory stimulant and methods for the use thereof |
| WO2021021236A1 (en) * | 2019-07-26 | 2021-02-04 | Heteron Biotechnologies, Llc | Breath analyzer and urea breath test method |
| KR20260053367A (ko) * | 2023-08-14 | 2026-04-21 | 뉴림 파머슈티칼스(1991) 리미티드 | Gal475 조성물 및 그의 사용 방법 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3031450A (en) * | 1959-04-30 | 1962-04-24 | Thomae Gmbh Dr K | Substituted pyrimido-[5, 4-d]-pyrimidines |
| JPS557430B2 (enExample) | 1972-05-17 | 1980-02-25 | ||
| US4963541A (en) | 1989-02-22 | 1990-10-16 | Abbott Laboratories | Pyrimido-pyrimidine lipoxygenase inhibiting compounds |
| US5075290A (en) * | 1989-06-28 | 1991-12-24 | University Of Virginia Alumni Patents Foundation | Use of adenosine, adenosine analogs or nucleoside uptake blockers, e.g. dipyridamole, as drug treatments for obstructive sleep apnea and snoring |
| US5679650A (en) * | 1993-11-24 | 1997-10-21 | Fukunaga; Atsuo F. | Pharmaceutical compositions including mixtures of an adenosine compound and a catecholamine |
| US6232312B1 (en) * | 1995-06-07 | 2001-05-15 | Cell Pathways, Inc. | Method for treating patient having precancerous lesions with a combination of pyrimidopyrimidine derivatives and esters and amides of substituted indenyl acetic acides |
| DE102004002557A1 (de) * | 2004-01-17 | 2005-08-04 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verwendung von substituierten Pyrimido(5,4-d)pyrimidinen zur Behandlung von Atemwegserkrankungen |
| EP2061440A2 (en) * | 2007-04-04 | 2009-05-27 | Sigmoid Pharma Limited | A pharmaceutical composition of tacrolimus |
| EP2646423A4 (en) | 2010-11-29 | 2014-04-30 | Galleon Pharmaceuticals Inc | NOVEL COMPOUNDS AS RESPIRATORY STIMULANTS FOR THE TREATMENT OF RESPIRATORY DISORDERS OR DISEASES |
-
2014
- 2014-03-13 MX MX2015013137A patent/MX2015013137A/es unknown
- 2014-03-13 EA EA201591693A patent/EA201591693A1/ru unknown
- 2014-03-13 JP JP2016501967A patent/JP2016516714A/ja active Pending
- 2014-03-13 SG SG11201507140PA patent/SG11201507140PA/en unknown
- 2014-03-13 US US14/776,391 patent/US9643971B2/en active Active
- 2014-03-13 CN CN201480027978.5A patent/CN105209041A/zh active Pending
- 2014-03-13 CA CA2905950A patent/CA2905950A1/en not_active Abandoned
- 2014-03-13 AU AU2014234095A patent/AU2014234095A1/en not_active Abandoned
- 2014-03-13 BR BR112015023671A patent/BR112015023671A2/pt not_active IP Right Cessation
- 2014-03-13 HK HK16107336.0A patent/HK1219234A1/zh unknown
- 2014-03-13 EP EP14768540.8A patent/EP2968329A4/en not_active Withdrawn
- 2014-03-13 WO PCT/US2014/025792 patent/WO2014151462A1/en not_active Ceased
- 2014-03-13 KR KR1020157029551A patent/KR20150143498A/ko not_active Withdrawn
-
2015
- 2015-09-22 ZA ZA2015/07064A patent/ZA201507064B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX2015013137A (es) | 2016-05-05 |
| US9643971B2 (en) | 2017-05-09 |
| WO2014151462A4 (en) | 2014-11-13 |
| AU2014234095A1 (en) | 2015-10-08 |
| EP2968329A1 (en) | 2016-01-20 |
| SG11201507140PA (en) | 2015-10-29 |
| CA2905950A1 (en) | 2014-09-25 |
| ZA201507064B (en) | 2017-01-25 |
| EP2968329A4 (en) | 2016-09-28 |
| HK1219234A1 (zh) | 2017-03-31 |
| JP2016516714A (ja) | 2016-06-09 |
| KR20150143498A (ko) | 2015-12-23 |
| CN105209041A (zh) | 2015-12-30 |
| WO2014151462A1 (en) | 2014-09-25 |
| BR112015023671A2 (pt) | 2017-07-18 |
| US20160046635A1 (en) | 2016-02-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EA201990665A1 (ru) | Регуляторы hpk1 на основе производных пиразолопиридина и их применение для лечения рака | |
| EA201590933A1 (ru) | Новые перорально биодоступные соединения, модулирующие контроль дыхания, и способы их использования | |
| EA201891374A1 (ru) | Замещенные 2-фенил-3-(пиперазинметил)имидазопиридины и их применение | |
| PH12014500468A1 (en) | Heterocyclic compounds and uses thereof | |
| EA201591290A3 (ru) | Креноланиб для лечения пролиферативных расстройств, связанных с мутацией flt3 | |
| MX2021007268A (es) | Formas solidas de acido {[5-(3-clorofenil)-3-hidroxipiridin-2-carb onil]amino}acetico, composiciones, y usos de las mismas. | |
| MX368781B (es) | Compuesto inhibidor de las actividades de las cinasas btk y/o jak3. | |
| WO2015054619A3 (en) | Use of a pcsk9 inhibitor to treat hyperlipidemia | |
| PH12014501997A1 (en) | Esketamine for the treatment of treatment-refractory or treatment-resistant depression | |
| EA202090043A1 (ru) | Диазабициклические замещенные имидазопиримидины и их применение | |
| MX2015002289A (es) | Anticuerpos humanos para gfr alfa 3 y métodos para su uso. | |
| NZ630367A (en) | Methods of treatment of pediatric solid tumor | |
| BR112015017775A2 (pt) | enzima cistationina beta-sintase para o tratamento de homocistinúria | |
| EA032955B1 (ru) | Применение производного глутаримида для лечения эозинофильных заболеваний | |
| EA202091020A1 (ru) | Замещенные имидазопиридинамиды и их применение | |
| MX2017006938A (es) | Terapia de combinacion para el tratamiento de cancer. | |
| EA201290209A1 (ru) | Новые модуляторы бензопиран киназы | |
| EA201691656A2 (ru) | Терапевтические способы с применением норибогаина и родственных соединений | |
| EA201300131A1 (ru) | Комбинированная фармацевтическая композиция и методы лечения заболеваний или состояний, связанных с респираторными заболеваниями или состояниями | |
| EA201492102A1 (ru) | Антагонисты lingo-2 для лечения заболеваний, в которых участвуют двигательные нейроны | |
| MX2015013137A (es) | Compuestos novedosos de modulación del control de la respiración, y sus métodos de uso. | |
| EA201600318A1 (ru) | Циклические тиеноурацилкарбоксамиды и их применение | |
| MX381932B (es) | Composicion intranasal que comprende betahistina. | |
| MY193963A (en) | Composition for treating joint diseases and kit containing same | |
| WO2013181217A3 (en) | Novel compounds and compositions for treatment of breathing control disorders or diseases |