BR112015023671A2 - novos compostos para modulação controlada de respiração e método de uso dos mesmos. - Google Patents

novos compostos para modulação controlada de respiração e método de uso dos mesmos.

Info

Publication number
BR112015023671A2
BR112015023671A2 BR112015023671A BR112015023671A BR112015023671A2 BR 112015023671 A2 BR112015023671 A2 BR 112015023671A2 BR 112015023671 A BR112015023671 A BR 112015023671A BR 112015023671 A BR112015023671 A BR 112015023671A BR 112015023671 A2 BR112015023671 A2 BR 112015023671A2
Authority
BR
Brazil
Prior art keywords
new compounds
controlled breathing
breathing modulation
modulation
controlled
Prior art date
Application number
BR112015023671A
Other languages
English (en)
Portuguese (pt)
Inventor
Suna Edgars
Joseph Mencel James
Shubin Kirill
Martjuga Marina
Dax Scott
Ozola Vita
Original Assignee
Galleon Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galleon Pharmaceuticals Inc filed Critical Galleon Pharmaceuticals Inc
Publication of BR112015023671A2 publication Critical patent/BR112015023671A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/541Non-condensed thiazines containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891Coated capsules; Multilayered drug free capsule shells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/16Central respiratory analeptics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Otolaryngology (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)
BR112015023671A 2013-03-15 2014-03-13 novos compostos para modulação controlada de respiração e método de uso dos mesmos. BR112015023671A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361792185P 2013-03-15 2013-03-15
PCT/US2014/025792 WO2014151462A1 (en) 2013-03-15 2014-03-13 Novel breathing control modulating compounds, and methods of using same

Publications (1)

Publication Number Publication Date
BR112015023671A2 true BR112015023671A2 (pt) 2017-07-18

Family

ID=51580966

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015023671A BR112015023671A2 (pt) 2013-03-15 2014-03-13 novos compostos para modulação controlada de respiração e método de uso dos mesmos.

Country Status (14)

Country Link
US (1) US9643971B2 (enExample)
EP (1) EP2968329A4 (enExample)
JP (1) JP2016516714A (enExample)
KR (1) KR20150143498A (enExample)
CN (1) CN105209041A (enExample)
AU (1) AU2014234095A1 (enExample)
BR (1) BR112015023671A2 (enExample)
CA (1) CA2905950A1 (enExample)
EA (1) EA201591693A1 (enExample)
HK (1) HK1219234A1 (enExample)
MX (1) MX2015013137A (enExample)
SG (1) SG11201507140PA (enExample)
WO (1) WO2014151462A1 (enExample)
ZA (1) ZA201507064B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105340281B (zh) 2013-07-05 2019-06-28 索尼公司 发送装置、发送方法、接收装置和接收方法
NO346258B1 (en) * 2015-06-30 2022-05-16 Neurad Ltd Novel breathing control modulating compounds, and methods of making and using same
US20210244742A1 (en) * 2015-07-22 2021-08-12 John Hsu Composition comprising a therapeutic agent and a respiratory stimulant and methods for the use thereof
WO2021021236A1 (en) * 2019-07-26 2021-02-04 Heteron Biotechnologies, Llc Breath analyzer and urea breath test method
KR20260053367A (ko) * 2023-08-14 2026-04-21 뉴림 파머슈티칼스(1991) 리미티드 Gal475 조성물 및 그의 사용 방법

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3031450A (en) * 1959-04-30 1962-04-24 Thomae Gmbh Dr K Substituted pyrimido-[5, 4-d]-pyrimidines
JPS557430B2 (enExample) 1972-05-17 1980-02-25
US4963541A (en) 1989-02-22 1990-10-16 Abbott Laboratories Pyrimido-pyrimidine lipoxygenase inhibiting compounds
US5075290A (en) * 1989-06-28 1991-12-24 University Of Virginia Alumni Patents Foundation Use of adenosine, adenosine analogs or nucleoside uptake blockers, e.g. dipyridamole, as drug treatments for obstructive sleep apnea and snoring
US5679650A (en) * 1993-11-24 1997-10-21 Fukunaga; Atsuo F. Pharmaceutical compositions including mixtures of an adenosine compound and a catecholamine
US6232312B1 (en) * 1995-06-07 2001-05-15 Cell Pathways, Inc. Method for treating patient having precancerous lesions with a combination of pyrimidopyrimidine derivatives and esters and amides of substituted indenyl acetic acides
DE102004002557A1 (de) * 2004-01-17 2005-08-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verwendung von substituierten Pyrimido(5,4-d)pyrimidinen zur Behandlung von Atemwegserkrankungen
EP2061440A2 (en) * 2007-04-04 2009-05-27 Sigmoid Pharma Limited A pharmaceutical composition of tacrolimus
EP2646423A4 (en) 2010-11-29 2014-04-30 Galleon Pharmaceuticals Inc NOVEL COMPOUNDS AS RESPIRATORY STIMULANTS FOR THE TREATMENT OF RESPIRATORY DISORDERS OR DISEASES

Also Published As

Publication number Publication date
EA201591693A1 (ru) 2016-03-31
MX2015013137A (es) 2016-05-05
US9643971B2 (en) 2017-05-09
WO2014151462A4 (en) 2014-11-13
AU2014234095A1 (en) 2015-10-08
EP2968329A1 (en) 2016-01-20
SG11201507140PA (en) 2015-10-29
CA2905950A1 (en) 2014-09-25
ZA201507064B (en) 2017-01-25
EP2968329A4 (en) 2016-09-28
HK1219234A1 (zh) 2017-03-31
JP2016516714A (ja) 2016-06-09
KR20150143498A (ko) 2015-12-23
CN105209041A (zh) 2015-12-30
WO2014151462A1 (en) 2014-09-25
US20160046635A1 (en) 2016-02-18

Similar Documents

Publication Publication Date Title
IL281549A (en) Compositions and methods for growth factor modulation
IL270943A (en) Biomarkers and methods of treating pd-1 and pd-l1 related conditions
BR112014023162A2 (pt) compostos e métodos para modulação quinase e indicações dos mesmos
IL256291B (en) Novel breathing control modulating compounds, and methods of making and using same
CL2016001080A1 (es) Benzamidas sustituidas para tratamiento de artrópodos.
IL244682B (en) Systems and methods of treatment using intervention and tasking determination
BR112016008193A2 (pt) Método para remoção de sox de gás com o uso de solução de complexo álcool-amina
CL2016000685A1 (es) Material para protección balística, su método de preparación y uso.
BR112016000489A2 (pt) composto, composição farmacêutica que o compreende, uso da composição e métodos para fabricar compostos
HUE053282T2 (hu) Vegyületek és eljárások epilepsziás rendellenesség kezelésére
PT3166937T (pt) Compostos antiproliferativos e métodos de uso dos mesmos
BR112015002868A2 (pt) dispositivos, sistemas e métodos para se engajar tecido
PL3012012T3 (pl) Urządzenie filtracyjne, zastosowanie takiego urządzenia filtracyjnego, oraz sposób pracy takiego urządzenia filtracyjnego
PL3804863T5 (pl) Sposób aplikacji i system aplikacji
BR112015026975A2 (pt) dispositivos, conjuntos e métodos para remoção de material ósseo
PT3036247T (pt) Método e sistema para tratar lenhina
BR112015002968A2 (pt) dispositivo para vestir e método para fabricar o mesmo
DK3054976T3 (da) Anvendelse af semaphorin-4d-bindende molekyler til behandling af aterosklerose
PL2997284T3 (pl) Sposób eksploatacji układu napędowego oraz układ napędowy
BR112015021732A2 (pt) dispositivo para uso terapêutico
DK3038654T3 (da) Ny anvendelse
PT3200906T (pt) Método de operação de um misturador descontínuo e misturador descontínuo para implementação do método
PT2951866T (pt) Dispositivo optoeletrónico e método para produzir o mesmo
BR112015022347A2 (pt) composição para vacinação, método para produzir uma composição para vacinação e uso de composição
CL2016001369A1 (es) Procedimiento para la preparación de un emulsionado de aceite en agua

Legal Events

Date Code Title Description
B08F Application fees: dismissal - article 86 of industrial property law
B08K Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87)