EA201390413A1 - Применение миелоидных клеток в качестве биомаркеров в диагностике рака - Google Patents

Применение миелоидных клеток в качестве биомаркеров в диагностике рака

Info

Publication number
EA201390413A1
EA201390413A1 EA201390413A EA201390413A EA201390413A1 EA 201390413 A1 EA201390413 A1 EA 201390413A1 EA 201390413 A EA201390413 A EA 201390413A EA 201390413 A EA201390413 A EA 201390413A EA 201390413 A1 EA201390413 A1 EA 201390413A1
Authority
EA
Eurasian Patent Office
Prior art keywords
biomarkers
myeloid cells
application
cell carcinoma
colorectal cancer
Prior art date
Application number
EA201390413A
Other languages
English (en)
Russian (ru)
Inventor
Харприт Сингх
Штеффен Вальтер
Регина Мендрцик
Винченцо Бронте
Сузанна Мандруццато
Original Assignee
Имматикс Байотекнолоджиз Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Имматикс Байотекнолоджиз Гмбх filed Critical Имматикс Байотекнолоджиз Гмбх
Publication of EA201390413A1 publication Critical patent/EA201390413A1/ru

Links

Classifications

    • G01N33/575
    • G01N33/57535
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047Cells of the immune system
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5751
    • G01N33/57525
    • G01N33/5753

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Hospice & Palliative Care (AREA)
  • Gastroenterology & Hepatology (AREA)
EA201390413A 2010-09-21 2011-09-21 Применение миелоидных клеток в качестве биомаркеров в диагностике рака EA201390413A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38478410P 2010-09-21 2010-09-21
GBGB1015765.9A GB201015765D0 (en) 2010-09-21 2010-09-21 Use of myeloid cell biomarkers for the diagnosis of cancer
PCT/EP2011/066397 WO2012038463A2 (en) 2010-09-21 2011-09-21 Use of myeloid cell biomarkers for the diagnosis of cancer

Publications (1)

Publication Number Publication Date
EA201390413A1 true EA201390413A1 (ru) 2013-07-30

Family

ID=43065538

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201390413A EA201390413A1 (ru) 2010-09-21 2011-09-21 Применение миелоидных клеток в качестве биомаркеров в диагностике рака

Country Status (10)

Country Link
US (1) US9671404B2 (enExample)
EP (1) EP2619585B1 (enExample)
JP (1) JP5970459B2 (enExample)
KR (1) KR20130137635A (enExample)
CN (1) CN103180739B (enExample)
CA (1) CA2811070A1 (enExample)
EA (1) EA201390413A1 (enExample)
GB (1) GB201015765D0 (enExample)
SG (2) SG188543A1 (enExample)
WO (1) WO2012038463A2 (enExample)

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EP3682896A1 (en) * 2011-04-28 2020-07-22 University of Southern California Human myeloid derived suppressor cell cancer markers
WO2013169913A1 (en) * 2012-05-08 2013-11-14 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Predictors of patient response to interferon-a therapy
US20160030558A1 (en) * 2013-03-13 2016-02-04 Health Research, Inc. Enhancement of vaccines
CN103743907B (zh) * 2013-07-24 2015-04-15 北京大学人民医院 测定造血干细胞移植后患者骨髓微循环环境评测的试剂盒、系统及方法
WO2015048748A1 (en) * 2013-09-30 2015-04-02 Board Of Regents, The University Of Texas System Myeloid-derived suppressor cell-specific peptides for diagnostic and therapeutic use
CN103626846B (zh) * 2013-11-08 2016-06-01 上海交通大学 与MDSCs特异性结合的配体多肽及药物输送系统
EP3012271A1 (en) * 2014-10-24 2016-04-27 Effimune Method and compositions for inducing differentiation of myeloid derived suppressor cell to treat cancer and infectious diseases
WO2016210241A1 (en) * 2015-06-26 2016-12-29 Beth Israel Deaconess Medical Center, Inc. Cancer therapy targeting tetraspanin 33 (tspan33) in myeloid derived suppressor cells
MX2018002640A (es) * 2015-09-02 2018-06-20 Syndax Pharmaceuticals Inc Seleccion de pacientes para la terapia de combinacion.
KR102883915B1 (ko) 2015-12-16 2025-11-18 시애틀 프로젝트 코포레이션 신생항원 동정, 제조, 및 용도
GB201604490D0 (en) 2016-03-16 2016-04-27 Immatics Biotechnologies Gmbh Peptides combination of peptides for use in immunotherapy against cancers
EP4438626A3 (en) 2016-04-14 2024-12-04 OSE Immunotherapeutics New anti-sirpa antibodies and their therapeutic applications
NZ754222A (en) 2016-12-08 2022-02-25 Immatics Biotechnologies Gmbh T cell receptors with improved pairing
DE102016123893A1 (de) 2016-12-08 2018-06-14 Immatics Biotechnologies Gmbh T-Zellrezeptoren mit verbesserter Bindung
CN107102127B (zh) * 2017-04-07 2019-08-06 东北师范大学 一种人体外周血中单核样髓源抑制细胞的检测方法
AU2018269039B2 (en) 2017-05-19 2025-05-15 Syndax Pharmaceuticals, Inc. Combination therapies
WO2018221820A1 (ko) * 2017-06-02 2018-12-06 이종균 대장 직장암 환자와 정상인의 말초혈액 내 면역세포의 분포 차이를 이용하여 면역력을 평가하고 암 발병 유무에 대한 정보를 제공하는 방법 및 이를 이용한 진단키트
JP7227237B2 (ja) 2017-10-10 2023-02-21 グリットストーン バイオ インコーポレイテッド ホットスポットを利用した新生抗原の特定
US11713356B2 (en) 2017-10-13 2023-08-01 Ose Immunotherapeutics Modified bifunctional anti-human signal regulatory protein alpha (SIRPa) antibody and method of use thereof for treating cancer
US11885815B2 (en) 2017-11-22 2024-01-30 Gritstone Bio, Inc. Reducing junction epitope presentation for neoantigens
KR102216725B1 (ko) * 2017-12-29 2021-02-17 연세대학교 산학협력단 면역 항암 요법에 대한 치료 반응 예측 방법
CA3091468A1 (en) 2018-03-13 2019-09-19 Ose Immunotherapeutics Use of anti-human sirpa v1 antibodies and method for producing anti-sirpa v1 antibodies
WO2019217484A1 (en) 2018-05-07 2019-11-14 Syndax Pharmaceuticals, Inc. Selection of patients for combination therapy
CN110501483B (zh) * 2019-07-25 2020-12-29 同济大学 一种中草药活性的检测方法
TR202003833A1 (tr) 2020-03-12 2021-09-21 Hacettepe Ueniversitesi Rektoerluek Mi̇yeloi̇d kökenli̇ baskilayici hücrelere özgü bi̇yobeli̇rteç paneli̇
EP4347653A1 (en) 2021-06-04 2024-04-10 Boehringer Ingelheim International GmbH Anti-sirp-alpha antibodies
CN117054649A (zh) * 2023-08-04 2023-11-14 广州中医药大学第一附属医院 一种慢性萎缩性胃炎向胃癌转化标志物及其应用
CN117030580B (zh) * 2023-09-15 2024-07-16 广州市第一人民医院(广州消化疾病中心、广州医科大学附属市一人民医院、华南理工大学附属第二医院) LDNs在坏死性小肠结肠炎诊断中的应用

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AUPM322393A0 (en) 1993-12-24 1994-01-27 Austin Research Institute, The Mucin carbohydrate compounds and their use in immunotherapy
US20040136973A1 (en) * 2002-11-07 2004-07-15 Eliezer Huberman Human stem cell materials and methods
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Also Published As

Publication number Publication date
CN103180739B (zh) 2016-08-03
CN103180739A (zh) 2013-06-26
SG188543A1 (en) 2013-04-30
JP5970459B2 (ja) 2016-08-17
JP2013539857A (ja) 2013-10-28
US9671404B2 (en) 2017-06-06
WO2012038463A3 (en) 2012-07-26
EP2619585A2 (en) 2013-07-31
GB201015765D0 (en) 2010-10-27
KR20130137635A (ko) 2013-12-17
SG10201510470WA (en) 2016-01-28
WO2012038463A2 (en) 2012-03-29
US20120070461A1 (en) 2012-03-22
CA2811070A1 (en) 2012-03-29
EP2619585B1 (en) 2017-03-01

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