EA201370078A1 - Ингибиторы вируса гепатита с - Google Patents
Ингибиторы вируса гепатита сInfo
- Publication number
- EA201370078A1 EA201370078A1 EA201370078A EA201370078A EA201370078A1 EA 201370078 A1 EA201370078 A1 EA 201370078A1 EA 201370078 A EA201370078 A EA 201370078A EA 201370078 A EA201370078 A EA 201370078A EA 201370078 A1 EA201370078 A1 EA 201370078A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- hepatitis
- new compounds
- virus inhibitors
- compositions containing
- compounds
- Prior art date
Links
- 241000711549 Hepacivirus C Species 0.000 title abstract 4
- 239000003112 inhibitor Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- 239000000203 mixture Substances 0.000 abstract 2
- 101800001014 Non-structural protein 5A Proteins 0.000 abstract 1
- 239000003443 antiviral agent Substances 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2010/050138 WO2012039717A1 (en) | 2010-09-24 | 2010-09-24 | Hepatitis c virus inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA201370078A1 true EA201370078A1 (ru) | 2013-11-29 |
Family
ID=43037168
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201370078A EA201370078A1 (ru) | 2010-09-24 | 2010-09-24 | Ингибиторы вируса гепатита с |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP2619195A1 (cg-RX-API-DMAC10.html) |
| JP (1) | JP5619289B2 (cg-RX-API-DMAC10.html) |
| CN (1) | CN103249730A (cg-RX-API-DMAC10.html) |
| BR (1) | BR112013008148A2 (cg-RX-API-DMAC10.html) |
| CA (1) | CA2812699A1 (cg-RX-API-DMAC10.html) |
| EA (1) | EA201370078A1 (cg-RX-API-DMAC10.html) |
| MX (1) | MX2013002927A (cg-RX-API-DMAC10.html) |
| WO (1) | WO2012039717A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2853531A3 (en) | 2009-06-11 | 2015-08-12 | AbbVie Bahamas Ltd. | Antiviral compounds |
| US8937150B2 (en) | 2009-06-11 | 2015-01-20 | Abbvie Inc. | Anti-viral compounds |
| US8354419B2 (en) | 2009-07-16 | 2013-01-15 | Vertex Pharmaceuticals Incorporated | Benzimidazole analogues for the treatment or prevention of flavivirus infections |
| WO2011119853A1 (en) | 2010-03-24 | 2011-09-29 | Vertex Pharmaceuticals Incorporated | Analogues for the treatment or prevention of flavivirus infections |
| NZ605440A (en) | 2010-06-10 | 2014-05-30 | Abbvie Bahamas Ltd | Solid compositions comprising an hcv inhibitor |
| BR112013004520A2 (pt) | 2010-08-26 | 2016-06-07 | Univ Emory | inibidores potentes e seletivos do virus da hepatite c |
| US10201584B1 (en) | 2011-05-17 | 2019-02-12 | Abbvie Inc. | Compositions and methods for treating HCV |
| WO2013030750A1 (en) | 2011-09-01 | 2013-03-07 | Lupin Limited | Antiviral compounds |
| US9034832B2 (en) | 2011-12-29 | 2015-05-19 | Abbvie Inc. | Solid compositions |
| US9073943B2 (en) | 2012-02-10 | 2015-07-07 | Lupin Limited | Antiviral compounds with a dibenzooxaheterocycle moiety |
| DK2855453T3 (en) | 2012-06-04 | 2017-02-06 | Actelion Pharmaceuticals Ltd | Benzimidazol-proline derivatives |
| BR112015007516A2 (pt) | 2012-10-10 | 2017-07-04 | Actelion Pharmaceuticals Ltd | antagonistas do receptor de orexina que são derivados de [orto bi-(hetero-)aril]-[2-(meta bi-(hetero-)aril)- pirrolidin-1-il]-metanona |
| CN105051040A (zh) | 2013-03-12 | 2015-11-11 | 埃科特莱茵药品有限公司 | 作为食欲素受体拮抗剂的氮杂环丁烷酰胺衍生物 |
| US11484534B2 (en) | 2013-03-14 | 2022-11-01 | Abbvie Inc. | Methods for treating HCV |
| SI3077391T1 (sl) | 2013-12-04 | 2018-11-30 | Idorsia Pharmaceuticals Ltd | Uporaba benzimidazol-prolinskih derivatov |
| WO2015103490A1 (en) | 2014-01-03 | 2015-07-09 | Abbvie, Inc. | Solid antiviral dosage forms |
| CA3055680A1 (en) | 2017-03-31 | 2018-10-04 | Syngenta Participations Ag | Fungicidal compositions |
| GB201803342D0 (en) | 2018-03-01 | 2018-04-18 | Medimmune Ltd | Methods |
| GB201806022D0 (en) | 2018-04-12 | 2018-05-30 | Medimmune Ltd | Pyrrolobenzodiazepines and conjugates thereof |
| CN113631560B (zh) | 2019-03-15 | 2025-02-18 | 麦迪穆有限责任公司 | 氮杂环丁烷并苯并二氮杂䓬二聚体和用于治疗癌症的包含它们的缀合物 |
| WO2024259085A2 (en) * | 2023-06-14 | 2024-12-19 | Alexion Pharmaceuticals, Inc. | Methods for the synthesis of complement factor d inhibitors and intermediates thereof |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY140680A (en) | 2002-05-20 | 2010-01-15 | Bristol Myers Squibb Co | Hepatitis c virus inhibitors |
| AU2003261434A1 (en) | 2002-08-12 | 2004-02-25 | Bristol-Myers Squibb Company | Iminothiazolidinones as inhibitors of hcv replication |
| US7420079B2 (en) | 2002-12-09 | 2008-09-02 | Bristol-Myers Squibb Company | Methods and compounds for producing dipeptidyl peptidase IV inhibitors and intermediates thereof |
| US7135462B2 (en) | 2003-11-20 | 2006-11-14 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| DE102004036971B4 (de) | 2004-07-30 | 2009-07-30 | Advanced Micro Devices, Inc., Sunnyvale | Technik zur Bewertung lokaler elektrischer Eigenschaften in Halbleiterbauelementen |
| US8303944B2 (en) | 2006-08-11 | 2012-11-06 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US8329159B2 (en) * | 2006-08-11 | 2012-12-11 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| JP2010034721A (ja) * | 2008-07-28 | 2010-02-12 | Fujitsu Ltd | パケットキャプチャ装置,パケットキャプチャ方法およびパケットキャプチャプログラム |
| WO2010065668A1 (en) * | 2008-12-03 | 2010-06-10 | Presidio Pharmaceuticals, Inc. | Inhibitors of hcv ns5a |
| US8796466B2 (en) * | 2009-03-30 | 2014-08-05 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US8138215B2 (en) * | 2009-05-29 | 2012-03-20 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
-
2010
- 2010-09-24 MX MX2013002927A patent/MX2013002927A/es not_active Application Discontinuation
- 2010-09-24 CN CN2010800703399A patent/CN103249730A/zh active Pending
- 2010-09-24 BR BR112013008148A patent/BR112013008148A2/pt not_active IP Right Cessation
- 2010-09-24 CA CA2812699A patent/CA2812699A1/en not_active Abandoned
- 2010-09-24 EA EA201370078A patent/EA201370078A1/ru unknown
- 2010-09-24 JP JP2013530121A patent/JP5619289B2/ja not_active Expired - Fee Related
- 2010-09-24 WO PCT/US2010/050138 patent/WO2012039717A1/en not_active Ceased
- 2010-09-24 EP EP10761101.4A patent/EP2619195A1/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP2619195A1 (en) | 2013-07-31 |
| JP5619289B2 (ja) | 2014-11-05 |
| JP2013537905A (ja) | 2013-10-07 |
| WO2012039717A1 (en) | 2012-03-29 |
| CA2812699A1 (en) | 2012-03-29 |
| MX2013002927A (es) | 2013-05-30 |
| BR112013008148A2 (pt) | 2016-08-09 |
| CN103249730A (zh) | 2013-08-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EA201101240A1 (ru) | Ингибиторы вируса гепатита с | |
| EA201171152A1 (ru) | Ингибиторы вируса гепатита c | |
| MX2013002927A (es) | Inhibidores del virus de la hepatitis c. | |
| EA201270555A1 (ru) | Комбинации ингибиторов вируса гепатита с | |
| EA201390155A1 (ru) | Комбинации ингибиторов вируса гепатита с | |
| EA201001275A1 (ru) | Конформационно-ограниченные бифенильные производные для применения в качестве ингибиторов вируса гепатита с | |
| EA201491361A1 (ru) | Ингибиторы вируса гепатита c | |
| EA201270622A1 (ru) | Ингибиторы вируса гепатита с | |
| EA201390190A1 (ru) | Ингибиторы вируса гепатита с | |
| EA200900676A1 (ru) | Ингибиторы вируса гепатита с | |
| EA201270656A1 (ru) | Ингибиторы вируса гепатита с | |
| EA201001273A1 (ru) | Ингибиторы вируса гепатита с | |
| EA201391637A1 (ru) | Ингибиторы вируса гепатита c | |
| EA201390538A1 (ru) | Противовирусные соединения | |
| EA201391152A1 (ru) | Ингибиторы вируса гепатита с | |
| EA201491179A1 (ru) | 2',4'-дифтор-2'-метил замещенные нуклеозидные производные в качестве ингибиторов репликации рнк вируса гепатита с | |
| EA201001274A1 (ru) | Имидазолилбифенильные имидазолы в качестве ингибиторов вируса гепатита с | |
| EA201171208A1 (ru) | Ингибиторы вируса гепатита с | |
| EA201370017A1 (ru) | Ингибиторы вируса гепатита с | |
| EA201171174A1 (ru) | Ингибиторы репликации вируса гепатита c | |
| EA201101082A1 (ru) | Ингибиторы вируса гепатита с | |
| CO6190510A2 (es) | Inhibidores del virus de la hepatitis c | |
| ATE469155T1 (de) | Cyclopropyl-fusionierte indolbenzazepin-hcv-ns5b- hemmer | |
| ATE483712T1 (de) | Hcv-ns5b-inhibitoren | |
| NO20091845L (no) | Macrocykliske peptider som hepatitt C virus-inhibitorer |