EA201290790A1 - Биоадгезивные композиции местных анестетиков - Google Patents
Биоадгезивные композиции местных анестетиковInfo
- Publication number
- EA201290790A1 EA201290790A1 EA201290790A EA201290790A EA201290790A1 EA 201290790 A1 EA201290790 A1 EA 201290790A1 EA 201290790 A EA201290790 A EA 201290790A EA 201290790 A EA201290790 A EA 201290790A EA 201290790 A1 EA201290790 A1 EA 201290790A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- local anesthetics
- bioadhesive compositions
- compositions
- bioadhesive
- swelling
- Prior art date
Links
- 239000000227 bioadhesive Substances 0.000 title abstract 2
- 239000003589 local anesthetic agent Substances 0.000 title abstract 2
- 229960005015 local anesthetics Drugs 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 239000012074 organic phase Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000008961 swelling Effects 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
- A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
- A61L2/0023—Heat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Anesthesiology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Biochemistry (AREA)
- Emergency Medicine (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE1050322 | 2010-04-01 | ||
| US32542510P | 2010-04-19 | 2010-04-19 | |
| PCT/EP2011/055025 WO2011121082A1 (en) | 2010-04-01 | 2011-03-31 | Bioadhesive compositions of local anaesthetics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA201290790A1 true EA201290790A1 (ru) | 2013-04-30 |
Family
ID=44278867
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201290790A EA201290790A1 (ru) | 2010-04-01 | 2011-03-31 | Биоадгезивные композиции местных анестетиков |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20130079371A1 (enExample) |
| EP (1) | EP2552409A1 (enExample) |
| JP (1) | JP2013523694A (enExample) |
| KR (1) | KR20130080435A (enExample) |
| CN (1) | CN102869344A (enExample) |
| AU (1) | AU2011234415C1 (enExample) |
| BR (1) | BR112012024885A2 (enExample) |
| CA (1) | CA2794280A1 (enExample) |
| CL (1) | CL2012002705A1 (enExample) |
| EA (1) | EA201290790A1 (enExample) |
| IL (1) | IL222225A0 (enExample) |
| MX (1) | MX2012011261A (enExample) |
| NZ (1) | NZ602540A (enExample) |
| PH (1) | PH12012501887A1 (enExample) |
| SG (1) | SG184072A1 (enExample) |
| WO (1) | WO2011121082A1 (enExample) |
| ZA (1) | ZA201206989B (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9642912B2 (en) | 2006-03-06 | 2017-05-09 | Crescita Therapeutics Inc. | Topical formulations for treating skin conditions |
| US9308181B2 (en) | 2006-03-06 | 2016-04-12 | Nuvo Research Inc. | Topical formulations, systems and methods |
| US20110229565A1 (en) | 2008-09-17 | 2011-09-22 | Karp Jeffrey M | Drug Delivery Composition Comprising a Self-Assembled Gelator |
| JP2013540757A (ja) | 2010-09-24 | 2013-11-07 | ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッド | カプセル化された作用物質の放出を制御する能力を有するナノ構造ゲル |
| US10220093B2 (en) | 2013-02-28 | 2019-03-05 | Mira Pharma Corporation | Long-acting semi-solid lipid formulations |
| EP2961380B1 (en) * | 2013-02-28 | 2020-04-08 | Mira Pharma Corporation | Injectable long-acting local anesthetic semi-solid formulations and its compositions |
| GB201317718D0 (en) | 2013-10-07 | 2013-11-20 | Buzzz Pharmaceuticals Ltd | Novel formulation |
| JP6678946B2 (ja) | 2015-03-25 | 2020-04-15 | テルモ株式会社 | ゲル状局所麻酔剤およびそれを用いたゲル状局所麻酔製剤 |
| EP3375456B1 (en) | 2015-11-12 | 2023-05-03 | Terumo Kabushiki Kaisha | Sustained-release topically administered agent |
| WO2018144991A1 (en) | 2017-02-03 | 2018-08-09 | The Brigham And Women's Hospital, Inc. | Self-assembled gels formed with anti-retroviral drugs, prodrugs thereof, and pharmaceutical uses thereof |
| US10881745B2 (en) * | 2017-05-08 | 2021-01-05 | Alivio Therapeutics, Inc. | Formulation of nanostructured gels for increased agent loading and adhesion |
| US10561606B2 (en) | 2017-12-06 | 2020-02-18 | Mira Pharma Corporation | Injectable long-acting local anesthetic semi-solid gel formulations |
| US11426418B2 (en) | 2017-12-06 | 2022-08-30 | Mira Pharma Corporation | Injectable long-acting semi-solid gel formulations |
| JP7046396B2 (ja) | 2017-12-06 | 2022-04-04 | 湖州惠中濟世生物科技有限公司 | 注射可能な長時間作用性局所麻酔薬半固形製剤 |
| US11839605B2 (en) | 2018-10-11 | 2023-12-12 | Alivio Therapeutics, Inc. | Non-injectable hydrogel formulations for smart release |
| EP4284272A4 (en) * | 2021-01-29 | 2024-12-25 | Insitu Biologics, Inc. | COMPOSITIONS AND METHODS OF SUSTAINED TREATMENT OF PAIN |
| CN118697692B (zh) * | 2024-06-27 | 2024-11-26 | 山东中医药大学附属医院 | 一种防苦麻醉胶浆剂、方法及应用 |
| CN119587525B (zh) * | 2024-11-07 | 2025-09-05 | 海南三帝制药有限公司 | 一种二甲卡因复合制剂及其制备方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5045553A (en) * | 1987-06-24 | 1991-09-03 | Fujisawa Pharmaceutical Company, Ltd. | Pharmaceutical composition for percutaneous drug absorption and percutaneous drug absorption promoter |
| WO1995026715A2 (en) * | 1994-03-30 | 1995-10-12 | Dumex-Alpharma A/S | Use of fatty acid esters as bioadhesive substances |
| SE9601421D0 (sv) | 1996-04-12 | 1996-04-12 | Astra Ab | New composition |
| ATE214599T1 (de) * | 1996-10-14 | 2002-04-15 | Kowa Co | Lokalanästhetikum zur aüsserlichen anwendung |
| US20040001889A1 (en) * | 2002-06-25 | 2004-01-01 | Guohua Chen | Short duration depot formulations |
| WO2004071398A2 (en) * | 2003-02-17 | 2004-08-26 | Cipla Ltd | Pharmaceutical patch |
| US20050084508A1 (en) | 2003-07-22 | 2005-04-21 | Vancaillie Thierry G. | Topical anesthesia formulation for bodily cavities |
| EP1848403B8 (en) * | 2005-01-14 | 2010-05-19 | Camurus Ab | Topical bioadhesive formulations |
| JP4931369B2 (ja) | 2005-05-31 | 2012-05-16 | ポーラ化成工業株式会社 | リポソームおよびそれを含む処置用の組成物 |
| CA2623561C (en) * | 2005-09-27 | 2015-04-28 | Efrat Biopolymers Ltd. | Gelling hydrophobic injectable polymer compositions |
| GB0524958D0 (en) * | 2005-12-07 | 2006-01-18 | Pharmakodex Ltd | Transdermal administration of active agents |
| US20070280972A1 (en) * | 2006-04-25 | 2007-12-06 | Zars, Inc. | Adhesive solid gel-forming formulations for dermal drug delivery |
| US20070269386A1 (en) * | 2006-05-16 | 2007-11-22 | Per Steen | New product and use and manufacture thereof |
| JP5181320B2 (ja) * | 2006-10-18 | 2013-04-10 | ニチバン株式会社 | 皮膚刺激の少ない経皮吸収型製剤 |
| US9918934B2 (en) | 2006-12-12 | 2018-03-20 | Edgar Joel Acosta-Zara | Linker-based lecithin microemulsion delivery vehicles |
| US20090247494A1 (en) | 2008-04-01 | 2009-10-01 | Phillip Mark Kofsky | Omega-3 essential fatty acid composition and method for treatment of anal and colon-rectal disorders |
-
2011
- 2011-03-31 SG SG2012068250A patent/SG184072A1/en unknown
- 2011-03-31 CA CA2794280A patent/CA2794280A1/en not_active Abandoned
- 2011-03-31 PH PH1/2012/501887A patent/PH12012501887A1/en unknown
- 2011-03-31 JP JP2013501854A patent/JP2013523694A/ja active Pending
- 2011-03-31 CN CN2011800166567A patent/CN102869344A/zh active Pending
- 2011-03-31 BR BR112012024885A patent/BR112012024885A2/pt not_active IP Right Cessation
- 2011-03-31 NZ NZ602540A patent/NZ602540A/en not_active IP Right Cessation
- 2011-03-31 EP EP11711566A patent/EP2552409A1/en not_active Withdrawn
- 2011-03-31 KR KR1020127028642A patent/KR20130080435A/ko not_active Withdrawn
- 2011-03-31 EA EA201290790A patent/EA201290790A1/ru unknown
- 2011-03-31 US US13/638,519 patent/US20130079371A1/en not_active Abandoned
- 2011-03-31 MX MX2012011261A patent/MX2012011261A/es not_active Application Discontinuation
- 2011-03-31 AU AU2011234415A patent/AU2011234415C1/en not_active Ceased
- 2011-03-31 WO PCT/EP2011/055025 patent/WO2011121082A1/en not_active Ceased
-
2012
- 2012-09-18 ZA ZA2012/06989A patent/ZA201206989B/en unknown
- 2012-09-27 IL IL222225A patent/IL222225A0/en unknown
- 2012-09-27 CL CL2012002705A patent/CL2012002705A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20130079371A1 (en) | 2013-03-28 |
| SG184072A1 (en) | 2012-10-30 |
| JP2013523694A (ja) | 2013-06-17 |
| AU2011234415A1 (en) | 2012-10-18 |
| CA2794280A1 (en) | 2011-10-06 |
| MX2012011261A (es) | 2012-12-05 |
| WO2011121082A1 (en) | 2011-10-06 |
| EP2552409A1 (en) | 2013-02-06 |
| AU2011234415B2 (en) | 2014-04-10 |
| CN102869344A (zh) | 2013-01-09 |
| CL2012002705A1 (es) | 2013-02-01 |
| AU2011234415C1 (en) | 2014-07-10 |
| NZ602540A (en) | 2014-05-30 |
| PH12012501887A1 (en) | 2012-12-17 |
| BR112012024885A2 (pt) | 2016-06-21 |
| KR20130080435A (ko) | 2013-07-12 |
| IL222225A0 (en) | 2012-12-31 |
| ZA201206989B (en) | 2014-04-30 |
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