EA201170873A1 - Безопасное введение десмопрессина - Google Patents
Безопасное введение десмопрессинаInfo
- Publication number
- EA201170873A1 EA201170873A1 EA201170873A EA201170873A EA201170873A1 EA 201170873 A1 EA201170873 A1 EA 201170873A1 EA 201170873 A EA201170873 A EA 201170873A EA 201170873 A EA201170873 A EA 201170873A EA 201170873 A1 EA201170873 A1 EA 201170873A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- desmopressin
- treatment
- desmopressina
- safe
- diuresis
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/08—Inhaling devices inserted into the nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/02—Sprayers or atomisers specially adapted for therapeutic purposes operated by air or other gas pressure applied to the liquid or other product to be sprayed or atomised
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/11—Aldehydes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/095—Oxytocins; Vasopressins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/08—Inhaling devices inserted into the nose
- A61M15/085—Fixing means therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/27—General characteristics of the apparatus preventing use
- A61M2205/276—General characteristics of the apparatus preventing use preventing unwanted use
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Otolaryngology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pulmonology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
Описано семейство интраназальных спреев-дозаторов для введения одинаковых низких доз десмопрессина для достижения безопасного диуреза у пациентов-людей. Дозаторы по изобретению можно использовать при лечении ноктурии, первичного ночного диуреза, недержания, частого мочеиспускания, несахарного диабета или любого заболевания или синдрома, при котором полезно лечение десмопрессином или при котором безопасное временное подавление выработки мочи может привести к благоприятным воздействиям на здоровье или к повышенному удобству при контроле мочеиспускания.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13987108P | 2008-12-22 | 2008-12-22 | |
PCT/US2009/068962 WO2010075266A2 (en) | 2008-12-22 | 2009-12-21 | Safe desmopressin administration |
Publications (2)
Publication Number | Publication Date |
---|---|
EA201170873A1 true EA201170873A1 (ru) | 2012-02-28 |
EA028531B1 EA028531B1 (ru) | 2017-11-30 |
Family
ID=42168193
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201791732A EA201791732A1 (ru) | 2008-12-22 | 2009-12-21 | Безопасное введение десмопрессина |
EA201170873A EA028531B1 (ru) | 2008-12-22 | 2009-12-21 | Безопасный способ введения десмопрессина |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201791732A EA201791732A1 (ru) | 2008-12-22 | 2009-12-21 | Безопасное введение десмопрессина |
Country Status (19)
Country | Link |
---|---|
US (3) | US20120015880A1 (ru) |
EP (2) | EP2381923B2 (ru) |
JP (4) | JP5731396B2 (ru) |
KR (2) | KR101755042B1 (ru) |
CN (2) | CN105963834A (ru) |
AU (1) | AU2009330203B2 (ru) |
BR (1) | BRPI0923557A2 (ru) |
CA (1) | CA2747998C (ru) |
DK (1) | DK2381923T4 (ru) |
EA (2) | EA201791732A1 (ru) |
ES (1) | ES2692345T5 (ru) |
IL (1) | IL213699A (ru) |
MX (1) | MX2011006765A (ru) |
NZ (1) | NZ593613A (ru) |
PL (1) | PL2381923T3 (ru) |
PT (1) | PT2381923T (ru) |
SG (2) | SG172344A1 (ru) |
WO (1) | WO2010075266A2 (ru) |
ZA (1) | ZA201105420B (ru) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009021007A1 (en) * | 2007-08-06 | 2009-02-12 | Serenity Pharmaceuticals Corporation | Methods and devices for desmopressin drug delivery |
CN105963834A (zh) * | 2008-12-22 | 2016-09-28 | 阿勒根公司 | 鼻内去氨加压素给药 |
PT2442821T (pt) * | 2009-06-18 | 2017-09-29 | Allergan Inc | Administração segura de desmopressina |
DK3024474T3 (da) | 2013-07-23 | 2022-03-28 | Serenity Pharmaceuticals Llc | Sammensætninger omfattende desmopressin i kombination med en beta-3-adrenoreceptor-agonist |
US9925232B2 (en) * | 2013-07-23 | 2018-03-27 | Serenity Pharmaceuticals, Llc | Methods and compositions comprising desmopressin in combination with a 5-alpha reductase inhibitor |
CN106999538A (zh) | 2014-11-20 | 2017-08-01 | 阿勒根公司 | 包含去氨加压素与α‑肾上腺素能受体拮抗剂组合的方法和组合物 |
Family Cites Families (38)
Publication number | Priority date | Publication date | Assignee | Title |
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CS171787B1 (ru) | 1973-11-09 | 1976-11-29 | ||
US4148787A (en) | 1976-05-24 | 1979-04-10 | Ferring Ab | Antidiuretically effective polypeptide and a process for preparing the same |
US4771769A (en) | 1982-12-20 | 1988-09-20 | Schering Corporation | Hand held metered spray dispenser |
US4746508A (en) | 1983-06-06 | 1988-05-24 | Beth Israel Hospital Assn. | Drug administration |
US4548922A (en) | 1983-06-06 | 1985-10-22 | Beth Israel Hospital | Drug administration |
US5731303A (en) | 1985-12-04 | 1998-03-24 | Conrex Pharmaceutical Corporation | Transdermal and trans-membrane delivery compositions |
US5023252A (en) | 1985-12-04 | 1991-06-11 | Conrex Pharmaceutical Corporation | Transdermal and trans-membrane delivery of drugs |
US5112804A (en) | 1987-04-01 | 1992-05-12 | Temple University Of The Commonwealth System Of Higher Education | Pharmaceutical composition and method of intranasal administration |
US4944429A (en) | 1987-08-28 | 1990-07-31 | Schering Corporation | Manually-operable spray dispenser with locking mechanism |
US5154122A (en) | 1989-10-20 | 1992-10-13 | Sol Goldschmidt | Shipping device for suspended piece goods |
CN1060980A (zh) * | 1990-10-26 | 1992-05-13 | 蔡东林 | 多用电控自控微型喷雾器 |
US5314694A (en) | 1990-10-29 | 1994-05-24 | Alza Corporation | Transdermal formulations, methods and devices |
US5122383A (en) | 1991-05-17 | 1992-06-16 | Theratech, Inc. | Sorbitan esters as skin permeation enhancers |
US5212199A (en) | 1991-05-17 | 1993-05-18 | Theratech, Inc. | Sorbitan esters as skin permeation enhancers |
US5227169A (en) | 1991-05-17 | 1993-07-13 | Theratech, Inc. | Sorbitan esters as skin permeation enhancers |
IT1255895B (it) | 1992-10-20 | 1995-11-17 | Laura Chiodini | Composizioni farmaceutiche contenenti una calcitonina |
CA2166312C (en) * | 1993-06-29 | 2002-04-23 | Alan Harris | Compositions for nasal administration of desmopressin |
JPH11500646A (ja) * | 1995-06-07 | 1999-01-19 | オニール,アレクサンダー・ジョージ・ブライアン | 患者により制御される薬剤供給装置 |
US5763398A (en) * | 1996-06-20 | 1998-06-09 | Ferring B.V. | Nasal administration of desmopressin |
DE19723133A1 (de) | 1997-06-03 | 1998-12-10 | Caideil M P Teoranta Tourmakea | Austragvorrichtung für Medien |
US7335186B2 (en) | 1998-03-13 | 2008-02-26 | Alexander George Brian O'Neil | Patient controlled drug delivery device |
AU3421600A (en) | 1999-02-14 | 2000-08-29 | Ing. Erich Pfeiffer Gmbh | Dispenser for flowable media |
DE19938798A1 (de) | 1999-08-16 | 2001-03-01 | Pfeiffer Erich Gmbh & Co Kg | Spender für Flüssigkeiten oder für zähflüssige oder versprühbare Produkte |
DE19940236A1 (de) | 1999-08-25 | 2001-03-08 | Pfeiffer Erich Gmbh & Co Kg | Spender mit manuell betätigbarer Ausbringeinrichtung |
DE10110742A1 (de) | 2001-02-28 | 2002-09-05 | Pfeiffer Erich Gmbh & Co Kg | Spender für Medien |
US7244703B2 (en) * | 2001-06-22 | 2007-07-17 | Bentley Pharmaceuticals, Inc. | Pharmaceutical compositions and methods for peptide treatment |
JP4210215B2 (ja) | 2001-09-21 | 2009-01-14 | インジ エリッヒ プファイファ ゲーエムベーハ | 媒体リザーバを備えた投与装置とこれのためのポンプ装置 |
WO2003053400A1 (en) | 2001-12-19 | 2003-07-03 | Alza Corporation | Formulation & dosage form for the controlled delivery of therapeutic agents |
GB0210397D0 (en) * | 2002-05-07 | 2002-06-12 | Ferring Bv | Pharmaceutical formulations |
ITMI20021684A1 (it) * | 2002-07-29 | 2004-01-29 | Therapicon Srl | Composizione farmaceutica di peptide nasale |
US7186692B2 (en) * | 2002-12-17 | 2007-03-06 | Nastech Pharmaceutical Company Inc. | Compositions and methods for enhanced mucosal delivery and non-infused administration of Y2 receptor-binding peptides and methods for treating and preventing obesity |
EP1689419A4 (en) * | 2003-11-10 | 2009-01-14 | Reprise Biopharmaceutics Llc | PHARMACEUTICAL COMPOSITIONS WITH LOW DOSES OF DESMOPRESSIN |
ES2348303T3 (es) | 2003-12-08 | 2010-12-02 | Cpex Pharmaceuticals, Inc. | Composiciones farmacauticas y procedimientos de tratamiento con insulina. |
WO2007022345A2 (en) * | 2005-08-17 | 2007-02-22 | Fleming And Company, Pharmaceuticals | Vitamin b12 nasal spray and method of use |
CN1785448A (zh) * | 2005-11-11 | 2006-06-14 | 广东工业大学 | 医用防染式药雾吸入喷嘴 |
JP2009539856A (ja) * | 2006-06-08 | 2009-11-19 | シーペックス ファーマシューティカルズ インコーポレイテッド | インシュリン組成物 |
CN105963834A (zh) * | 2008-12-22 | 2016-09-28 | 阿勒根公司 | 鼻内去氨加压素给药 |
PT2442821T (pt) * | 2009-06-18 | 2017-09-29 | Allergan Inc | Administração segura de desmopressina |
-
2009
- 2009-12-21 CN CN201610282630.1A patent/CN105963834A/zh active Pending
- 2009-12-21 KR KR1020117017070A patent/KR101755042B1/ko not_active Application Discontinuation
- 2009-12-21 EP EP09796558.6A patent/EP2381923B2/en active Active
- 2009-12-21 EA EA201791732A patent/EA201791732A1/ru unknown
- 2009-12-21 SG SG2011046117A patent/SG172344A1/en unknown
- 2009-12-21 EA EA201170873A patent/EA028531B1/ru not_active IP Right Cessation
- 2009-12-21 MX MX2011006765A patent/MX2011006765A/es active IP Right Grant
- 2009-12-21 EP EP18174439.2A patent/EP3437633A1/en active Pending
- 2009-12-21 JP JP2011542539A patent/JP5731396B2/ja active Active
- 2009-12-21 BR BRPI0923557A patent/BRPI0923557A2/pt not_active Application Discontinuation
- 2009-12-21 KR KR1020177017968A patent/KR20170081711A/ko not_active Application Discontinuation
- 2009-12-21 NZ NZ593613A patent/NZ593613A/xx unknown
- 2009-12-21 CA CA2747998A patent/CA2747998C/en active Active
- 2009-12-21 AU AU2009330203A patent/AU2009330203B2/en active Active
- 2009-12-21 CN CN2009801560968A patent/CN102355888A/zh active Pending
- 2009-12-21 DK DK09796558.6T patent/DK2381923T4/da active
- 2009-12-21 PL PL09796558T patent/PL2381923T3/pl unknown
- 2009-12-21 WO PCT/US2009/068962 patent/WO2010075266A2/en active Application Filing
- 2009-12-21 PT PT09796558T patent/PT2381923T/pt unknown
- 2009-12-21 ES ES09796558T patent/ES2692345T5/es active Active
- 2009-12-21 US US13/141,590 patent/US20120015880A1/en not_active Abandoned
- 2009-12-21 SG SG10201509152VA patent/SG10201509152VA/en unknown
-
2011
- 2011-06-21 IL IL213699A patent/IL213699A/en active IP Right Grant
- 2011-07-22 ZA ZA2011/05420A patent/ZA201105420B/en unknown
-
2015
- 2015-04-09 JP JP2015080138A patent/JP5959076B2/ja active Active
-
2016
- 2016-06-17 JP JP2016120760A patent/JP6389209B2/ja active Active
-
2018
- 2018-06-14 JP JP2018113951A patent/JP2018184407A/ja active Pending
-
2019
- 2019-06-11 US US16/438,040 patent/US20200078542A1/en not_active Abandoned
-
2021
- 2021-05-26 US US17/330,798 patent/US20220126039A1/en not_active Abandoned
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