EA201100322A1 - Интерферон и любой агент, индуцирующий ингибирование протеинфосфатазы 2а, например интерлейкин-1 и по выбору рибавирин, для лечения гепатитов b или c - Google Patents
Интерферон и любой агент, индуцирующий ингибирование протеинфосфатазы 2а, например интерлейкин-1 и по выбору рибавирин, для лечения гепатитов b или cInfo
- Publication number
- EA201100322A1 EA201100322A1 EA201100322A EA201100322A EA201100322A1 EA 201100322 A1 EA201100322 A1 EA 201100322A1 EA 201100322 A EA201100322 A EA 201100322A EA 201100322 A EA201100322 A EA 201100322A EA 201100322 A1 EA201100322 A1 EA 201100322A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- interleukin
- factor
- ribavirin
- pharmaceutical composition
- proteinphosphatase
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2006—IL-1
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biotechnology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Настоящее изобретение относится к фармацевтическим комплектам, содержащим интерфероны в первом фармацевтическом составе, средства, вызывающие ингибирование протеинфосфатазы 2А (РР2А) во втором фармацевтическом составе, кроме того, содержащим рибавирин в третьем фармацевтическом составе, при этом средства, вызывающие ингибирование РР2А выбираются из группы, состоящей из инсулина, сенситайзеров инсулина, инсулиноподобного фактора роста-1, эпидермального фактора роста, фактора некроза опухолей, интерлейкина-1, интерлейкина-2, интерлейкина-3, интерлейкина-5, интерлейкина-6, интерлейкина-11, интерлейкина-12, интерлейкина-13, эритропоэтина, тромбопоэтина, гранулоцитарного колониестимулирующего фактора (G-CSF), гормона роста, пролактина, лептина, гранулоцитарно-моноцитарного колониестимулирующего фактора (GM-CSF), цилиарного нейротрофического фактора (CNTF), СТ-1, лейкоз ингибирующего фактора (LIF) и онкостатина М (OSM).
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP2008/059643 WO2010009762A1 (en) | 2008-07-23 | 2008-07-23 | Interferon and an agent inducing inhibition of protein phosphatase 2a such as interleukin- 1 and optionally ribavirin for the treatment of hbv or hcv infection |
Publications (3)
Publication Number | Publication Date |
---|---|
EA201100322A1 true EA201100322A1 (ru) | 2011-10-31 |
EA201100322A8 EA201100322A8 (ru) | 2013-06-28 |
EA022952B1 EA022952B1 (ru) | 2016-03-31 |
Family
ID=40996585
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201100322A EA022952B1 (ru) | 2008-07-23 | 2008-07-23 | Способ лечения вирусных гепатитов b и c |
Country Status (3)
Country | Link |
---|---|
EA (1) | EA022952B1 (ru) |
UA (1) | UA106591C2 (ru) |
WO (1) | WO2010009762A1 (ru) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2468815C1 (ru) * | 2011-08-08 | 2012-12-10 | Федеральное государственное бюджетное учреждение "Научный центр здоровья детей" Российской академии медицинских наук | Способ повышения эффективности интерферонотерапии хронического гепатита с у детей |
CN103071147A (zh) * | 2011-10-26 | 2013-05-01 | 麦德托尼克公司 | 干扰素-α向乙型肝炎感染的患者的连续皮下施用 |
WO2017053990A1 (en) | 2015-09-24 | 2017-03-30 | The Regents Of The University Of California | Synthetic sphingolipid-like molecules, drugs, methods of their synthesis and methods of treatment |
WO2022133494A1 (en) * | 2020-12-17 | 2022-06-23 | The Regents Of The University Of California | Antiviral compounds and applications thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997016204A1 (en) * | 1995-11-02 | 1997-05-09 | Schering Corporation | Continuous low-dose cytokine infusion therapy |
GB9609932D0 (en) * | 1996-05-13 | 1996-07-17 | Hoffmann La Roche | Use of IL-12 and IFN alpha for the treatment of infectious diseases |
EP1446142A1 (en) * | 2001-09-27 | 2004-08-18 | Igor Anatolievich Pomytkin | Potentiating the therapeutic effects of interferons |
WO2005071101A1 (en) * | 2004-01-23 | 2005-08-04 | University Hospital Of Basel | Treatment of hepatitis c infection by increasing stat1 methylation |
WO2006032711A1 (es) * | 2004-08-18 | 2006-03-30 | Instituto Científico Y Tecnológico De Navarra S.A. | Uso del factor de crecimiento semejante a la insulina tipo i y de interferón alfa en el tratamiento de una enfermedad hepática crónica, kit y composiciones que los comprenden |
ES2302402B1 (es) * | 2005-06-16 | 2009-05-08 | Proyecto De Biomedicina Cima, S.L. | Uso de una citoquina de la familia de interleuquina-6 en la preparacion de una composicion para administracion combinada con interferon-alfa. |
-
2008
- 2008-07-23 UA UAA201102255A patent/UA106591C2/ru unknown
- 2008-07-23 WO PCT/EP2008/059643 patent/WO2010009762A1/en active Application Filing
- 2008-07-23 EA EA201100322A patent/EA022952B1/ru not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EA022952B1 (ru) | 2016-03-31 |
EA201100322A8 (ru) | 2013-06-28 |
WO2010009762A1 (en) | 2010-01-28 |
UA106591C2 (ru) | 2014-09-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG MD TJ TM RU |