EA201001100A1 - Фармацевтическая композиция на основе гепатопротектора и пребиотика, получение и применение - Google Patents

Фармацевтическая композиция на основе гепатопротектора и пребиотика, получение и применение

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Publication number
EA201001100A1
EA201001100A1 EA201001100A EA201001100A EA201001100A1 EA 201001100 A1 EA201001100 A1 EA 201001100A1 EA 201001100 A EA201001100 A EA 201001100A EA 201001100 A EA201001100 A EA 201001100A EA 201001100 A1 EA201001100 A1 EA 201001100A1
Authority
EA
Eurasian Patent Office
Prior art keywords
hepatoprotector
prebiotic
pharmaceutical composition
composition based
prevention
Prior art date
Application number
EA201001100A
Other languages
English (en)
Other versions
EA019985B1 (ru
Inventor
Александр Владимирович ДИКОВСКИЙ
Борис Анатольевич РУДОЙ
Олег Валентинович ДОРОЖКО
Original Assignee
Александр Владимирович ДИКОВСКИЙ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Александр Владимирович ДИКОВСКИЙ filed Critical Александр Владимирович ДИКОВСКИЙ
Publication of EA201001100A1 publication Critical patent/EA201001100A1/ru
Publication of EA019985B1 publication Critical patent/EA019985B1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016—Disaccharides, e.g. lactose, lactulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Abstract

Изобретение относится к медицине, к гепатологии и фармакологии и может быть использовано для получения и применения фармацевтической композиции на основе гепатопротектора и пребиотика для лечения и профилактики заболеваний печени, обусловленных нарушением липидно-холестеринового обмена, и выбранных из группы: желчно-каменная болезнь преимущественно с холестериновыми камнями, алкогольный и неалкогольный стеатогепатит, билиарный цирроз печени, холестероз желчного пузыря, лекарственное и токсическое поражение печени. Фармацевтическая композиция предназначена для приема внутрь и включает в качестве активного начала гепатопротектор и пребиотик, взятых в терапевтически эффективных дозах. Данное изобретение способствует восстановлению функций печени в кратчайшие сроки и предотвращению рецидивов заболевания за счет восстановления холестеринового обмена и биоценоза кишечника, обусловленных синергидным взаимодействием гепатопректора и пребиотика, что обусловливает, также, предупреждение побочных действий гепатопротектора.
EA201001100A 2008-03-04 2008-03-04 Фармацевтическая композиция на основе гепатопротектора и пребиотика, получение и применение EA019985B1 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/RU2008/000122 WO2009110816A1 (ru) 2008-03-04 2008-03-04 Фармацевтическая композиция на основе гепатопротектора и пребиотика, получение и применение

Publications (2)

Publication Number Publication Date
EA201001100A1 true EA201001100A1 (ru) 2011-02-28
EA019985B1 EA019985B1 (ru) 2014-07-30

Family

ID=41056233

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201001100A EA019985B1 (ru) 2008-03-04 2008-03-04 Фармацевтическая композиция на основе гепатопротектора и пребиотика, получение и применение

Country Status (12)

Country Link
US (2) US9446058B2 (ru)
EP (1) EP2266619B1 (ru)
CN (1) CN102014960A (ru)
BR (1) BRPI0822449A2 (ru)
CY (1) CY1116601T1 (ru)
DK (1) DK2266619T3 (ru)
EA (1) EA019985B1 (ru)
ES (1) ES2545105T3 (ru)
HR (1) HRP20150849T1 (ru)
PL (1) PL2266619T3 (ru)
SI (1) SI2266619T1 (ru)
WO (1) WO2009110816A1 (ru)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104039327B (zh) * 2012-01-06 2017-02-15 大熊制药株式会社 含有牛磺熊去氧胆酸的组合物
WO2016100228A2 (en) 2014-12-15 2016-06-23 Nanosphere Health Sciences, Llc Methods of treating inflammatory disorders and global inflammation with compositions comprising phospholipid nanoparticle encapsulations of nsaids
CN106509889A (zh) * 2016-11-04 2017-03-22 山东维尼莱生物科技股份有限公司 一种对酒精性肝损伤有辅助保护作用的保健品
JP6772773B2 (ja) * 2016-11-14 2020-10-21 ブラザー工業株式会社 通信装置
CN111494333B (zh) * 2020-04-14 2022-06-14 安士制药（中山）有限公司 一种熊去氧胆酸胶囊及其制备方法
EP4147706A1 (en) * 2020-05-05 2023-03-15 Abou Nehmi Filho, Victor Composition for regulating the neuro-immune-endocrine system
CN115040545A (zh) * 2022-06-13 2022-09-13 江南大学 鸡胆粉在制备解酒护肝药物中的用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1283225B1 (it) * 1996-03-11 1998-04-16 Renata Maria Anna Ve Cavaliere Ceppi di batteri, composizione farmaceutica contenente uno o piu' di tali ceppi e uso dei medesimi per la prevenzione e la terapia delle
WO2001056547A2 (en) 2000-02-04 2001-08-09 Seo Hong Yoo Preparation of aqueous clear solution dosage forms with bile acids
JP3908513B2 (ja) 2001-11-19 2007-04-25 日本甜菜製糖株式会社 肝機能改善剤
RU2205637C1 (ru) * 2002-04-24 2003-06-10 Закрытое акционерное общество "Брынцалов-А" Гепатопротекторное средство "карсилин"
BG108250U (en) 2003-10-10 2005-04-30 "Софарма" Ад Probiotic food additive
CZ20033042A3 (cs) * 2003-11-10 2005-06-15 Naturprodukt Cz Spol. S R. O. Potravinový doplněk na bázi silymarinu
HUP0500582A1 (hu) * 2005-06-13 2007-08-28 Csaba Jozsef Dr Jaszberenyi Szinergetikus élettani hatású élelmiszerek, élelmiszer-adalékok és táplálék-kiegészítõk vagy takarmányadalékok
RU2310463C1 (ru) * 2006-05-19 2007-11-20 Закрытое акционерное общество "Партнер" Гепатопротекторный пробиотик

Also Published As

Publication number Publication date
PL2266619T3 (pl) 2015-10-30
EP2266619B1 (de) 2015-05-13
BRPI0822449A2 (pt) 2015-06-16
US9446058B2 (en) 2016-09-20
EP2266619A1 (de) 2010-12-29
ES2545105T3 (es) 2015-09-08
WO2009110816A1 (ru) 2009-09-11
US20160354387A1 (en) 2016-12-08
EA019985B1 (ru) 2014-07-30
SI2266619T1 (sl) 2015-11-30
CY1116601T1 (el) 2017-03-15
EP2266619A4 (de) 2011-07-20
US20110312910A1 (en) 2011-12-22
DK2266619T3 (en) 2015-08-24
CN102014960A (zh) 2011-04-13
HRP20150849T1 (hr) 2015-09-25

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