EA201001011A1 - Производное 15,16-метилен-17-(1'-пропенил)-17-3'-оксидоэстра-4-ен-3-она, его применение и лекарственное средство, содержащее указанное производное - Google Patents

Производное 15,16-метилен-17-(1'-пропенил)-17-3'-оксидоэстра-4-ен-3-она, его применение и лекарственное средство, содержащее указанное производное

Info

Publication number
EA201001011A1
EA201001011A1 EA201001011A EA201001011A EA201001011A1 EA 201001011 A1 EA201001011 A1 EA 201001011A1 EA 201001011 A EA201001011 A EA 201001011A EA 201001011 A EA201001011 A EA 201001011A EA 201001011 A1 EA201001011 A1 EA 201001011A1
Authority
EA
Eurasian Patent Office
Prior art keywords
derivatives
derivative
propenyl
oxydoestra
methylen
Prior art date
Application number
EA201001011A
Other languages
English (en)
Russian (ru)
Inventor
Ульрих Клар
Йоахим Кунке
Рольф Больманн
Ян Хюбнер
Свен Ринг
Томас Френцель
Фредерик Менгес
Штеффен Борден
Ханс-Петер Мун
Катя Прелле
Original Assignee
Байер Шеринг Фарма Акциенгезельшафт
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40585540&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201001011(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Байер Шеринг Фарма Акциенгезельшафт filed Critical Байер Шеринг Фарма Акциенгезельшафт
Publication of EA201001011A1 publication Critical patent/EA201001011A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C07J53/008—3 membered carbocyclic rings in position 15/16
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/42—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of mineralocorticosteroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
EA201001011A 2007-12-29 2008-12-23 Производное 15,16-метилен-17-(1'-пропенил)-17-3'-оксидоэстра-4-ен-3-она, его применение и лекарственное средство, содержащее указанное производное EA201001011A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102007063496A DE102007063496A1 (de) 2007-12-29 2007-12-29 15,16-Methylen-17-(1'-propenyl)-17-3'-oxidoestra-4-en-3-on-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
PCT/EP2008/011164 WO2009083271A1 (de) 2007-12-29 2008-12-23 15,16-methylen-17-(1'-propenyl)-17,3'-oxidoestra-4-en-3-on-derivat, dessen verwendung und das derivat enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
EA201001011A1 true EA201001011A1 (ru) 2011-02-28

Family

ID=40585540

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201001011A EA201001011A1 (ru) 2007-12-29 2008-12-23 Производное 15,16-метилен-17-(1'-пропенил)-17-3'-оксидоэстра-4-ен-3-она, его применение и лекарственное средство, содержащее указанное производное

Country Status (24)

Country Link
US (1) US8623850B2 (zh)
EP (1) EP2238148B1 (zh)
JP (1) JP5600070B2 (zh)
KR (1) KR20100110348A (zh)
CN (1) CN101918427B (zh)
AR (1) AR069963A1 (zh)
AU (1) AU2008342915A1 (zh)
BR (1) BRPI0821667A2 (zh)
CA (1) CA2710486A1 (zh)
CL (1) CL2008003921A1 (zh)
CO (1) CO6321233A2 (zh)
CR (1) CR11544A (zh)
DE (1) DE102007063496A1 (zh)
DO (1) DOP2010000202A (zh)
EA (1) EA201001011A1 (zh)
EC (1) ECSP10010317A (zh)
ES (1) ES2397970T3 (zh)
IL (1) IL206383A0 (zh)
PA (1) PA8809801A1 (zh)
PE (1) PE20091181A1 (zh)
TW (1) TW200938205A (zh)
UY (1) UY31581A1 (zh)
WO (1) WO2009083271A1 (zh)
ZA (1) ZA201005398B (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012059594A1 (en) 2010-11-04 2012-05-10 Bayer Pharma Aktiengesellschaft Mineralcorticoid receptor antagonists for the treatment of corticoid-induced obesity
TW201350122A (zh) * 2012-04-23 2013-12-16 Bayer Pharma AG １８－甲基－１５β，１６β－亞甲基－１９－降－２０－螺氧－４－烯－３－酮的子宮內用途，包含１８－甲基－１５β，１６β－亞甲基－１９－降－２０－螺氧－４－烯－３－酮的子宮內系統，及其於避孕及婦科治療之用途
CN110452279B (zh) * 2019-05-13 2022-04-08 株洲千金药业股份有限公司 三萜类化合物和其药学上可接受的盐及制备方法和应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1183500B (de) 1962-10-12 1964-12-17 Schering Ag Verfahren zur Herstellung von alpha, beta-Methylenketonen der Steroidreihe
US3705179A (en) 1971-03-15 1972-12-05 American Home Prod Antiandrogenic steroids
NL7701384A (nl) 1977-02-10 1978-08-14 Akzo Nv Werkwijze voor het bereiden van nieuwe steroiden van de oestraanreeks.
DE2922500A1 (de) 1979-05-31 1980-12-04 Schering Ag 6 beta .7 beta
DE3402329A1 (de) 1984-01-20 1985-08-01 Schering AG, 1000 Berlin und 4709 Bergkamen 6,6-ethylen-15,16-methylen-3-oxo-17(alpha)-pregn-4-en-21,17-carbolactone, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate
DE3410880A1 (de) * 1984-03-21 1985-10-03 Schering AG, Berlin und Bergkamen, 1000 Berlin 17-substituierte estradiene und estratriene
FR2598421B1 (fr) 1986-05-06 1988-08-19 Roussel Uclaf Nouveaux produits 19-nor ou 19-nor d-homo steroides substitues en position 11b par un radical phenyle portant un radical alkynyle, leur procede de preparation, leur application comme medicaments et les compositions les renfermant
DE3702383A1 (de) 1987-01-23 1988-08-04 Schering Ag 11ss-alkinylestrene und -estradiene, deren herstellung und diese enthaltende pharmazeutische praeparate
JP2605041B2 (ja) * 1987-05-30 1997-04-30 株式会社リコー 感熱記録材料
DE19651000A1 (de) 1996-12-01 1998-06-04 Schering Ag Oxyiminopregnancarbolactone
DE102004063864A1 (de) 2004-12-30 2006-07-13 Schering Ag 18-Methyl-19-nor-17-pregn-4-en21,17-carbolactone, sowie diese enthaltende pharmazeutische Präparate
DE102006030416A1 (de) 2006-06-29 2008-01-03 Bayer Schering Pharma Ag 18-Methyl-19-nor-androst-4-en-17,17-spiroether (18-Methyl-19-nor-20-spirox-4-en-3-one) sowie diese enthaltende pharmazeutische Präparate

Also Published As

Publication number Publication date
CN101918427B (zh) 2013-07-31
TW200938205A (en) 2009-09-16
CA2710486A1 (en) 2009-07-09
ECSP10010317A (es) 2010-08-31
AR069963A1 (es) 2010-03-03
IL206383A0 (en) 2010-12-30
CL2008003921A1 (es) 2010-02-12
BRPI0821667A2 (pt) 2015-06-16
DE102007063496A1 (de) 2009-07-02
EP2238148B1 (de) 2012-10-24
CR11544A (es) 2010-08-27
CO6321233A2 (es) 2011-09-20
US20110003779A1 (en) 2011-01-06
UY31581A1 (es) 2009-08-03
CN101918427A (zh) 2010-12-15
DOP2010000202A (es) 2010-07-31
PA8809801A1 (es) 2009-07-23
KR20100110348A (ko) 2010-10-12
WO2009083271A1 (de) 2009-07-09
JP5600070B2 (ja) 2014-10-01
JP2011507927A (ja) 2011-03-10
PE20091181A1 (es) 2009-09-03
EP2238148A1 (de) 2010-10-13
AU2008342915A1 (en) 2009-07-09
US8623850B2 (en) 2014-01-07
ES2397970T3 (es) 2013-03-12
ZA201005398B (en) 2012-12-27

Similar Documents

Publication Publication Date Title
TWI262917B (en) 2-Furancarboxylic hydrazides and pharmaceutical compositions containing the same
HK1062677A1 (en) 17Beta-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases
PH12021551257A1 (en) Cyclic pantetheine derivatives and uses thereof
NO20073257L (no) 18-methyl-19-nor-17-pregn-4-en-21,17-carbolactones and pharmaceutical preparations comprising the same
TW200716547A (en) Piperidin-4-yl-amide derivatives
UA102517C2 (ru) Замещенные производные морфолина и тиоморфолина, фармацевтическая композиция на их основе и их применение для производства лекарственного средства для лечения расстройства или заболевания центральной нервной системы
TW200621737A (en) 2-carbamide-4-phenylthiazole derivatives, preparation thereof and therapeutic use thereof
HRP20050103A2 (en) N-aryl piperidine substituted biphenylcarboxamides as inhibitors of apolipoprotein b secretion
TW200626158A (en) Naphthaline derivatives
EA200601194A1 (ru) Новые производные бензофурана, используемые для профилактики или лечения нарушений, связанных с 5-ht-рецептором
TW200736189A (en) Indene derivatives, their preparation and use as medicaments
TW200700069A (en) Benzothiazole, thiazolopyridine, benzooxazole and oxazolopyridine derivatives
ES2193875A1 (es) Derivados de benzoxazinona, su preparacion y su aplicacion como medicamentos.
DE602004008959D1 (de) Benzoäbüä1,4üdioxepinderivate
NO20050903L (no) Nye piperazinyl-pyrazinonderivater for behandling av 5HT-2A reseptorrelaterte forstyrrelser
MX2009012518A (es) Derivados de piperidina 4,4-disubstituidos.
EA201001011A1 (ru) Производное 15,16-метилен-17-(1'-пропенил)-17-3'-оксидоэстра-4-ен-3-она, его применение и лекарственное средство, содержащее указанное производное
MX2009005544A (es) Indoles.
MX2008001608A (es) Piperazinas acetilenicas como antagonistas de receptor de glutamato metabotropico.
MX2009006446A (es) Derivados de espiro-piperidina.
EA201001006A1 (ru) γ-ЛАКТОНОВОЕ ПРОИЗВОДНОЕ СТЕРОИДА 15,16-МЕТИЛЕН-17-ГИДРОКСИ-19-НОР-21-КАРБОНОВОЙ КИСЛОТЫ, ЕГО ПРИМЕНЕНИЕ И ЛЕКАРСТВЕННЫЕ СРЕДСТВА, СОДЕРЖАЩИЕ ПРОИЗВОДНОЕ
ECSP10010318A (es) Derivado de -lactona del esteroide del ácido 17-hidroxi-19-nor-21-carboxílico, su uso y el medicamento que lo contiene
DE602006017855D1 (de) Verwendung von n-(dibenz (b,f)oxepin-10-ylmethyl)-n-methyl-n-prop-2-inylamin (omigapil) zur prophylaxe und/oder behandlung von muskeldystrophie
ECSP10010316A (es) Derivado de 17-(1'-propenil)-17-3'-oxidoestra-4-en-3-ona, su uso y medicamentos que lo contienen
MX2010007967A (es) N-[3-bromo-2-cloro-4-(4,5-dihidro-1h-imidazol-2-ilmetil)-fenil]-m etansulfoamida como agonista parcial alfa-1 a adrenergico para el tratamiento de la incontinencia.