CR11544A - Derivado 15,16-metilen-17-(1'-propenil)-17-3'-oxidoestra-4-3-ona, su uso y medicamento que lo contiene - Google Patents

Derivado 15,16-metilen-17-(1'-propenil)-17-3'-oxidoestra-4-3-ona, su uso y medicamento que lo contiene

Info

Publication number
CR11544A
CR11544A CR11544A CR11544A CR11544A CR 11544 A CR11544 A CR 11544A CR 11544 A CR11544 A CR 11544A CR 11544 A CR11544 A CR 11544A CR 11544 A CR11544 A CR 11544A
Authority
CR
Costa Rica
Prior art keywords
oxidoestra
propenyl
methylen
ona
derivative
Prior art date
Application number
CR11544A
Other languages
English (en)
Inventor
Ulrich Klar
Joachim Kuhnke
Rolf Bohlmann
Jan Hubner
Sven Ring
Thomas Frenzel
Frederik Menges
Steffen Borden
Hans-Peter Muhn
Katja Prelle
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40585540&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR11544(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Publication of CR11544A publication Critical patent/CR11544A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C07J53/008—3 membered carbocyclic rings in position 15/16
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/42—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of mineralocorticosteroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

La invencion se refiere a derivados de 15,16-metilen-17-(1'-propenil)-17-3'-oxidoestra-4-en-3-ona que tienen la formula quimica general I, donde Z, R4, R6a, R6b, R7 y R18 tienen los significados indicados en la reinvindicacion 1 y sus solvatos, hidratos y sales.
CR11544A 2007-12-29 2010-06-29 Derivado 15,16-metilen-17-(1'-propenil)-17-3'-oxidoestra-4-3-ona, su uso y medicamento que lo contiene CR11544A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102007063496A DE102007063496A1 (de) 2007-12-29 2007-12-29 15,16-Methylen-17-(1'-propenyl)-17-3'-oxidoestra-4-en-3-on-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
CR11544A true CR11544A (es) 2010-08-27

Family

ID=40585540

Family Applications (1)

Application Number Title Priority Date Filing Date
CR11544A CR11544A (es) 2007-12-29 2010-06-29 Derivado 15,16-metilen-17-(1'-propenil)-17-3'-oxidoestra-4-3-ona, su uso y medicamento que lo contiene

Country Status (24)

Country Link
US (1) US8623850B2 (es)
EP (1) EP2238148B1 (es)
JP (1) JP5600070B2 (es)
KR (1) KR20100110348A (es)
CN (1) CN101918427B (es)
AR (1) AR069963A1 (es)
AU (1) AU2008342915A1 (es)
BR (1) BRPI0821667A2 (es)
CA (1) CA2710486A1 (es)
CL (1) CL2008003921A1 (es)
CO (1) CO6321233A2 (es)
CR (1) CR11544A (es)
DE (1) DE102007063496A1 (es)
DO (1) DOP2010000202A (es)
EA (1) EA201001011A1 (es)
EC (1) ECSP10010317A (es)
ES (1) ES2397970T3 (es)
IL (1) IL206383A0 (es)
PA (1) PA8809801A1 (es)
PE (1) PE20091181A1 (es)
TW (1) TW200938205A (es)
UY (1) UY31581A1 (es)
WO (1) WO2009083271A1 (es)
ZA (1) ZA201005398B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012059594A1 (en) 2010-11-04 2012-05-10 Bayer Pharma Aktiengesellschaft Mineralcorticoid receptor antagonists for the treatment of corticoid-induced obesity
TW201350122A (zh) * 2012-04-23 2013-12-16 Bayer Pharma AG １８－甲基－１５β，１６β－亞甲基－１９－降－２０－螺氧－４－烯－３－酮的子宮內用途，包含１８－甲基－１５β，１６β－亞甲基－１９－降－２０－螺氧－４－烯－３－酮的子宮內系統，及其於避孕及婦科治療之用途
CN110452279B (zh) * 2019-05-13 2022-04-08 株洲千金药业股份有限公司 三萜类化合物和其药学上可接受的盐及制备方法和应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1183500B (de) 1962-10-12 1964-12-17 Schering Ag Verfahren zur Herstellung von alpha, beta-Methylenketonen der Steroidreihe
US3705179A (en) 1971-03-15 1972-12-05 American Home Prod Antiandrogenic steroids
NL7701384A (nl) 1977-02-10 1978-08-14 Akzo Nv Werkwijze voor het bereiden van nieuwe steroiden van de oestraanreeks.
DE2922500A1 (de) 1979-05-31 1980-12-04 Schering Ag 6 beta .7 beta
DE3402329A1 (de) 1984-01-20 1985-08-01 Schering AG, 1000 Berlin und 4709 Bergkamen 6,6-ethylen-15,16-methylen-3-oxo-17(alpha)-pregn-4-en-21,17-carbolactone, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate
DE3410880A1 (de) * 1984-03-21 1985-10-03 Schering AG, Berlin und Bergkamen, 1000 Berlin 17-substituierte estradiene und estratriene
FR2598421B1 (fr) 1986-05-06 1988-08-19 Roussel Uclaf Nouveaux produits 19-nor ou 19-nor d-homo steroides substitues en position 11b par un radical phenyle portant un radical alkynyle, leur procede de preparation, leur application comme medicaments et les compositions les renfermant
DE3702383A1 (de) 1987-01-23 1988-08-04 Schering Ag 11ss-alkinylestrene und -estradiene, deren herstellung und diese enthaltende pharmazeutische praeparate
JP2605041B2 (ja) * 1987-05-30 1997-04-30 株式会社リコー 感熱記録材料
DE19651000A1 (de) 1996-12-01 1998-06-04 Schering Ag Oxyiminopregnancarbolactone
DE102004063864A1 (de) 2004-12-30 2006-07-13 Schering Ag 18-Methyl-19-nor-17-pregn-4-en21,17-carbolactone, sowie diese enthaltende pharmazeutische Präparate
DE102006030416A1 (de) 2006-06-29 2008-01-03 Bayer Schering Pharma Ag 18-Methyl-19-nor-androst-4-en-17,17-spiroether (18-Methyl-19-nor-20-spirox-4-en-3-one) sowie diese enthaltende pharmazeutische Präparate

Also Published As

Publication number Publication date
CN101918427B (zh) 2013-07-31
TW200938205A (en) 2009-09-16
CA2710486A1 (en) 2009-07-09
ECSP10010317A (es) 2010-08-31
AR069963A1 (es) 2010-03-03
IL206383A0 (en) 2010-12-30
CL2008003921A1 (es) 2010-02-12
BRPI0821667A2 (pt) 2015-06-16
DE102007063496A1 (de) 2009-07-02
EP2238148B1 (de) 2012-10-24
CO6321233A2 (es) 2011-09-20
US20110003779A1 (en) 2011-01-06
UY31581A1 (es) 2009-08-03
CN101918427A (zh) 2010-12-15
DOP2010000202A (es) 2010-07-31
PA8809801A1 (es) 2009-07-23
KR20100110348A (ko) 2010-10-12
WO2009083271A1 (de) 2009-07-09
EA201001011A1 (ru) 2011-02-28
JP5600070B2 (ja) 2014-10-01
JP2011507927A (ja) 2011-03-10
PE20091181A1 (es) 2009-09-03
EP2238148A1 (de) 2010-10-13
AU2008342915A1 (en) 2009-07-09
US8623850B2 (en) 2014-01-07
ES2397970T3 (es) 2013-03-12
ZA201005398B (en) 2012-12-27

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Legal Events

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