EA200800295A1 - Способы лечения эпилептогенеза - Google Patents
Способы лечения эпилептогенезаInfo
- Publication number
- EA200800295A1 EA200800295A1 EA200800295A EA200800295A EA200800295A1 EA 200800295 A1 EA200800295 A1 EA 200800295A1 EA 200800295 A EA200800295 A EA 200800295A EA 200800295 A EA200800295 A EA 200800295A EA 200800295 A1 EA200800295 A1 EA 200800295A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- group
- groups
- alkyl
- phenyl
- epileptogenesis
- Prior art date
Links
- 230000008579 epileptogenesis Effects 0.000 title abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69862505P | 2005-07-12 | 2005-07-12 | |
| PCT/US2006/026277 WO2007008551A2 (en) | 2005-07-12 | 2006-07-07 | Use of 2-phenyl-l, 2-ethanedi0l-(di) carbamates for treating epileptogenesis and epilepsy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA200800295A1 true EA200800295A1 (ru) | 2008-12-30 |
Family
ID=37637731
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200800295A EA200800295A1 (ru) | 2005-07-12 | 2006-07-07 | Способы лечения эпилептогенеза |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20070021501A1 (https=) |
| EP (1) | EP1906946A2 (https=) |
| JP (1) | JP2009501223A (https=) |
| KR (1) | KR20080028485A (https=) |
| CN (1) | CN101309680A (https=) |
| AR (1) | AR054550A1 (https=) |
| AU (1) | AU2006269462A1 (https=) |
| BR (1) | BRPI0613010A2 (https=) |
| CA (1) | CA2615127A1 (https=) |
| EA (1) | EA200800295A1 (https=) |
| EC (1) | ECSP088172A (https=) |
| IL (1) | IL188728A0 (https=) |
| NO (1) | NO20080739L (https=) |
| TW (1) | TW200744575A (https=) |
| WO (1) | WO2007008551A2 (https=) |
| ZA (1) | ZA200801402B (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102088990A (zh) * | 2008-05-16 | 2011-06-08 | 阿尔伯维塔公司 | 癫痫的治疗 |
| US8609849B1 (en) | 2010-11-30 | 2013-12-17 | Fox Chase Chemical Diversity Center, Inc. | Hydroxylated sulfamides exhibiting neuroprotective action and their method of use |
| EP2968210B1 (en) * | 2013-03-12 | 2024-09-11 | Bio-Pharm Solutions Co., Ltd. | Phenyl carbamate compounds for use in preventing or treating pediatric epilesy |
| US8652527B1 (en) | 2013-03-13 | 2014-02-18 | Upsher-Smith Laboratories, Inc | Extended-release topiramate capsules |
| US9101545B2 (en) | 2013-03-15 | 2015-08-11 | Upsher-Smith Laboratories, Inc. | Extended-release topiramate capsules |
| KR102481631B1 (ko) * | 2015-08-24 | 2022-12-27 | 조게닉스 인터내셔널 리미티드 | 펜플루라민을 사용하여 레녹스-가스토 증후군을 치료하는 방법 |
| ES3059582T3 (en) * | 2016-02-29 | 2026-03-23 | Bio Pharm Solutions Co Ltd | Sulfamate derivative compounds, processes for preparing them and their uses |
| US20190022166A1 (en) * | 2017-07-18 | 2019-01-24 | Creative Bio-Peptides Inc. | Oral anti-inflammatory peptides to treat epilepsy, seizures and cns disorders |
| USRE50630E1 (en) | 2017-10-31 | 2025-10-14 | Creative BioPeptides, Inc. | Use of an all-D-pentapeptide chemokine antagonist to reduce opioid dose in a person with pain |
| CN109920550A (zh) * | 2018-12-25 | 2019-06-21 | 天津大学 | 一种基于dMRI研究青少年肌阵挛性癫痫的方法 |
| US11510961B2 (en) | 2019-12-19 | 2022-11-29 | Creative Bio-Peptides, Inc. | Methods and compositions for use of a chemokine receptor antagonist peptide to treat addiction, substance abuse disorders or symptoms thereof |
| CN115501344A (zh) * | 2022-09-29 | 2022-12-23 | 重庆医科大学 | 一种铁螯合剂的应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3313692A (en) * | 1958-04-21 | 1967-04-11 | Armour Pharma | Method of inducing calming and muscle relaxation with carbamates |
| US3265728A (en) * | 1962-07-18 | 1966-08-09 | Armour Pharma | Substituted phenethyl carbamates |
| US5698588A (en) * | 1996-01-16 | 1997-12-16 | Yukong Limited | Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol |
| AU3304997A (en) * | 1996-05-31 | 1998-01-05 | Southern Illinois University | Methods of modulating aspects of brain neural plasticity by vagus nerve stimulation |
| CA2360258A1 (en) * | 1999-02-09 | 2000-08-17 | Timothy L. Macdonald | Felbamate derived compounds |
| MXPA03007717A (es) * | 2001-02-27 | 2005-11-08 | Johnson & Johnson | Compuestos de carbamato para su uso en la prevencion o tratamiento de trastornos bipolares. |
| PL364640A1 (en) * | 2001-02-27 | 2004-12-13 | Ortho-Mcneil Pharmaceutical, Inc. | Carbamate compounds for use in preventing or treating bipolar disorder |
-
2006
- 2006-07-06 US US11/481,626 patent/US20070021501A1/en not_active Abandoned
- 2006-07-07 CA CA002615127A patent/CA2615127A1/en not_active Abandoned
- 2006-07-07 BR BRPI0613010-0A patent/BRPI0613010A2/pt not_active IP Right Cessation
- 2006-07-07 EA EA200800295A patent/EA200800295A1/ru unknown
- 2006-07-07 EP EP06786434A patent/EP1906946A2/en not_active Withdrawn
- 2006-07-07 JP JP2008521432A patent/JP2009501223A/ja not_active Withdrawn
- 2006-07-07 CN CNA2006800333910A patent/CN101309680A/zh active Pending
- 2006-07-07 AU AU2006269462A patent/AU2006269462A1/en not_active Abandoned
- 2006-07-07 KR KR1020087003269A patent/KR20080028485A/ko not_active Withdrawn
- 2006-07-07 WO PCT/US2006/026277 patent/WO2007008551A2/en not_active Ceased
- 2006-07-11 TW TW095125162A patent/TW200744575A/zh unknown
- 2006-07-11 AR ARP060102976A patent/AR054550A1/es not_active Application Discontinuation
-
2008
- 2008-01-10 IL IL188728A patent/IL188728A0/en unknown
- 2008-02-11 NO NO20080739A patent/NO20080739L/no not_active Application Discontinuation
- 2008-02-11 ZA ZA200801402A patent/ZA200801402B/xx unknown
- 2008-02-12 EC EC2008008172A patent/ECSP088172A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2615127A1 (en) | 2007-01-18 |
| WO2007008551A3 (en) | 2008-06-19 |
| KR20080028485A (ko) | 2008-03-31 |
| BRPI0613010A2 (pt) | 2010-12-14 |
| NO20080739L (no) | 2008-04-10 |
| TW200744575A (en) | 2007-12-16 |
| ZA200801402B (en) | 2009-10-28 |
| EP1906946A2 (en) | 2008-04-09 |
| IL188728A0 (en) | 2008-11-03 |
| CN101309680A (zh) | 2008-11-19 |
| US20070021501A1 (en) | 2007-01-25 |
| JP2009501223A (ja) | 2009-01-15 |
| AR054550A1 (es) | 2007-06-27 |
| ECSP088172A (es) | 2008-03-26 |
| WO2007008551A2 (en) | 2007-01-18 |
| AU2006269462A1 (en) | 2007-01-18 |
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